Browsing by Author "Atli, M."

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Biochemical and Histochemical Study on the Hypothalamus at Some Periods of Starvation and Refeeding After Starvation
(Asian Journal of Chemistry, 2007) Temur, A.; Atli, M.; Karadag, H.; Donmez, H. H.; Askerov, F.
This study was carried out to determine biochemical and histochemical alterations in the lateral (feeding centre) and ventro-medial (satiety centre) nuclei of hypothalamus in rats starved and refed after some periods of starvation. 180 Wistar albino rats were used in the investigation. The rats were starved for a periods of 1, 3, 5 and 7 d. The rats starved 5 d were refed for a periods of 5, 10, 15 and 30 d. The activity of the neutral peptide hydrolase was biochemically determined in the hypothalamus. In addition, histochemical investigation was made in the feeding and satiety centres. It was observed that the activity of the neutral peptide hydrolase became closer to the levels of the control group at 30th d of refeeding after 5 d starvation. It was concluded that the feeding centre was more sensitive to starvation than the satiety centre and the satiety centre was restored earlier than the feeding centre.
Serum Paraoxonase Activity and Lipid Hydroperoxide Levels in Adult Football Players After Three Days Football Tournament
(Makerere Univ, Fac Med, 2013) Atli, M.
Background: It has been suggested that physical activity is an important factor in the prevention and treatment of cardiovascular diseases. Low serum paraoxononase-1 (PON1) activity is with an associated risk of atherosclerotic disease. Objectives: In this study, we aimed to investigate serum PON1 activity and lipid hydroperoxide (LOOH) levels in adult football players after three days football tournament. Methods: Twenty-three adult male football players and 23 sedentary male subjects after three days football tournament were enrolled. Serum paraoxonase, arylesterase activities and LOOH levels were determined. Results: Serum paraoxonase and arylesterase activities were signiucantly higher in football players than sedentary subjects (all, p<0.05), while LOOH levels were significantly lower (p<0.05). Serum LOOH levels were inversely correlated with paraoxonase and arylesterase activities (r=-0.552, p<0.001; r=-0.812, p<0.001; respectively) in adult football players. Conclusion: Our data show, for the first time, that physical activity is associated with increased PON1 activity and decreased oxidative stress after three days football tournament. In addition, physical activity for a healthy life is important in increasing serum PON1 activity, and this may play a role in the prevention of atherosclerosis.