Browsing by Author "Aydin, Yener"

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Comparison of Conventional Magnetic Resonance Imaging, Cine-Magnetic Resonance Imaging, and Operation Findings in Invasion Assessment of Esophageal Cancer
(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2017) Ozgokce, Mesut; Alper, Fatih; Sade, Recep; Yavuz, Alpaslan; Ogul, Hayri; Aydin, Yener; Eroglu, Atilla
Background: This study aims to compare the conventional magneticresonance imaging and cine-magnetic resonance imaging findings with the operation results in terms of invasion existence in esophageal cancer. Methods: This prospective study included a total of 37 suspected cases (21 males, 16 females; mean age 63.3 years; range 28 to 81 years) with respect to whether or not invasion in esophageal masses between January 2012 and February 2016. Initially, conventional magnetic resonance imaging (T-1-weighted, T-2-weighted, short tau inversion recovery), lesion characteristics and invasion areas were evaluated in all cases. The cases with invasion were re-evaluated according to dynamic moving features of the lesion and adjacent tissue by cine-magnetic resonance imaging in three planes. The relative motion of the mass with adjacent tissues, fatty planes, and invasion status were evaluated according to size and structure. Results: The presence of invasion was detected by conventional magnetic resonance imaging in all of the cases. Invasion was not detected in 28 of 37 cases, while it was observed in nine cases by cine-magnetic resonance imaging. Twenty of 28 non-invasion cases were operated and results were compatible with the cine-magnetic resonance imaging results. The remaining eight cases were not operated due to severe comorbidities and the refusal of operation. Conclusion: Cine-magnetic resonance imaging may contribute to detect invasion accurately in esophagus cancer which is adjacent to moving tissues such as heart and main vascular structures. Based on our study results, cine-magnetic resonance imaging appears to be superior to conventional magnetic resonance imaging.
Doubling Time in Pulmonary and Hepatic Hydatid Cysts
(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2024) Aydin, Yener; Ozgokce, Mesut; Ulas, Ali Bilal; Durmaz, Fatma; Kasali, Kamber; Eren, Suat; Eroglu, Atilla
Background: This study aims to investigate whether the concept of doubling time in hydatid cysts differs according to different parameters such as age, sex, and whether the cyst is located in the lung or liver. Methods: Between January 2012 and August 2023, a total of 138 hydatid cysts were retrospectively analyzed. There were 55 pulmonary (32 males, 23 females; mean age: 25.6 +/- 23.8 years; range, 2 to 77 years) and 83 hepatic hydatid cyst patients (32 males, 51 females; mean age: 31.1 +/- 22.8 years; range, 3 to 75 years). Results: The mean doubling times for pulmonary and hepatic hydatid cysts were 73.4 +/- 41.8 and 172.6 +/- 108.8 days, respectively (p<0.001). When children (<= 18 years old) and adult cases were compared for pulmonary hydatid cysts, the mean doubling times were 61.1 +/- 17.6 and 87.1 +/- 55.3 days, respectively (p=0.119), and for hepatic hydatid cysts, 110.6 +/- 48.4 and 215.6 +/- 118.3 days, respectively (p<0.001). While comparing male and female cases, the mean doubling time for pulmonary hydatid cysts was 77.6 +/- 32.2 and 67.6 +/- 52.6 days, respectively (p=0.018), while for hepatic hydatid cysts, it was 192.0 +/- 111.7 and 160.4 +/- 106.2 days, respectively (p=0.250). Conclusion: The doubling time seems to be approximately 10 weeks in the lung and approximately 25 weeks in the liver. Hydatid cysts grow faster in children than adults in both the lungs and liver.
The Efficiency of Diffusion-Weighted Magnetic Resonance Imaging in the Differentiation of Malign and Benign Cavitary Lung Lesions
(Lippincott Williams & Wilkins, 2023) Durmaz, Fatma; Ozgokce, Mesut; Aydin, Yener; Yildiz, Hanifi; Ozkacmaz, Sercan; Dundar, Ilyas; Goya, Cemil
Purpose:The present study investigates the diagnostic efficiency of apparent diffusion coefficient (ADC) values in differentiating between malignant and benign cavitary lesions on diffusion-weighted magnetic resonance imaging (DWI). Materials and Methods:This prospective study included 45 consecutive patients identified with a cavitary lung lesion with a wall thickness of >= 5 mm on thoracic computed tomography in our clinic between 2020 and 2022, and who underwent thoracic DWI within 1 week of their original computed tomography. ADC measurements were made on DWI by drawing a region of interest manually from the cavity wall, away from the lung parenchyma in the axial section where the lesion was best demonstrated. The patients were then classified into benign and malignant groups based on the pathology or clinico-radiologic follow-up. Results:The sample included 29 (64.4%) male and 16 (35.6%) female patients, with a mean age of 59.06 +/- 17.3 years. Included in the study were 1 patient with 3 and 3 patients with 2 cavitary lesions each, with a total for the sample of 50 cavitary lesions. There were 23 (46%) malignant and 27 (54%) benign cavitary lung lesions. The mean ADC value (x10(-3) mm(2)/s) of the malignant and benign cavitary lesions was 0.977 +/- 0.522 (0.511 to 2.872) and 1.383 +/- 0.370 (0.930 to 2.213), respectively. The findings were statistically significant using an independent samples t test (P=0.002). The mean wall thickness of the malignant and benign lesions was 12.47 +/- 5.51 mm (5 to 25 mm) and 10.11 +/- 4.65 mm (5 to 22 mm), respectively. Although malignant cavities had a higher mean wall thickness than benign cavities, the difference was statistically insignificant (P=0.104). Conclusion:A significant difference was identified between the ADC values measured in DWI of the malignant and benign cavitary lung lesions. DWI, a noninvasive and rapid imaging method, can provide useful information for the differential diagnosis of cavitary lesions and can minimize unnecessary biopsies.
Giant Lung and Liver Hydatid Cyst in a 3-Year Child
(Soc Brasileira Medicina Tropical, 2022) Ozgokce, Mesut; Ayengin, Kemal; Aydin, Yener
A Life-Threatening Complication of Hydatid Cyst: Tension Pneumothorax
(Soc Brasileira Medicina Tropical, 2024) Aydin, Yener; Ozgokce, Mesut; Durmaz, Fatma
Özofagus Kanserinde İnvazyonun Değerlendirilmesinde Konvansiyonel Manyetik Rezonans Görüntüleme, Sine-manyetik Rezonans Görüntüleme ve Ameliyat Bulgularının Karşılaştırılması
(2017) Eroğlu, Atila; Aydin, Yener; Yavuz, Alpaslan; Batur, Abdussamed; Alper, Fatih; Oğul, Hayri; Ozgokce, Mesut
Amaç: Bu çalışmada özofagus kanserinde konvansiyonel manyetik rezonans görüntüleme ve sine- manyetik rezonans görüntüleme ile invazyon varlığı açısından ortaya çıkan bulgular ameliyat sonuçları ile karşılaştırıldı.Çalışma planı: Bu prospektif çalışmaya Ocak 2012 - Şubat 2016 tarihleri arasında özofagusta tespit edilen kitlelerde invazyon varlığı ya da yokluğu açısından şüpheli toplam 37 olgu (21 erkek, 16 kadın; ort. yaş 63.3 yıl; dağılım 28-81 yıl) alındı. Tüm olgularda öncelikle konvansiyonel manyetik rezonans görüntüleme (T1- ağırlıklı, T2-ağırlıklı, short tau inversion recovery) ile lezyon özellikleri ve invazyon alanları araştırıldı. İnvazyonlu olgular, lezyonun dinamik özellikleri ve komşu dokular üç planda sine -manyetik rezonans görüntüleme alınarak tekrar değerlendirildi. Kitlenin komşu dokular ile olan bağıl hareketi, yağlı düzlemler ve invazyon durumu, boyut ve yapıya göre değerlendirildi.Bulgular: Olguların tümünde konvansiyonel manyetik rezonans görüntüleme ile invazyon varlığı saptandı. Otuz yedi olgudan 28’inde sine-manyetik rezonans görüntüleme ile invazyon saptanmaz iken, dokuz olguda tespit edildi. İnvazyon tespit edilmeyen 28 olgunun 20’si ameliyat edildi ve sonuçlar sine -manyetik rezonans görüntüleme bulguları ile uyumlu idi. Kalan sekiz olgu ise, ciddi komorbiditeler ve ameliyatı reddetme nedeni ile ameliyat edilemedi.Sonuç: Kalp ve ana vasküler yapılar gibi hareketli dokulara yakın komşulukta olan özofagus kanserinde invazyonun doğru tespit edilmesinde sine-manyetik rezonans görüntüleme katkı sağlayabilir. Çalışma sonuçlarımıza göre, sine-manyetik rezonans görüntüleme, konvansiyonel manyetik rezonans görüntülemeden üstün görünmektedir.
Usability of Transthoracic Shear Wave Elastography in Differentiation of Subpleural Solid Masses
(Lippincott Williams & Wilkins, 2018) Ozgokce, Mesut; Yavuz, Alpaslan; Akbudak, Ibrahim; Durmaz, Fatma; Uney, Ibrahim; Aydin, Yener; Dundar, Ilyas
In this study, the effectiveness of transthoracic ultrasound elastography in the benign and malign distinction of subpleural/pleural solid lesions was investigated.Between July 2015 and December 2016, 33 consecutive patients with subpleural solid lesions detected via computed tomography (CT) of the thorax were identified and prospectively included in this study. The average for each lesion's shear wave velocity (SWV) value was detected, and benign and malignant lesions' SWV values are statistically compared. The CT and pathology results were used as a reference to compare these values. A receiver operating characteristic analysis was used to determine the cutoff value for benign/malignant neoplasms.The 33 patients (10 female, 23 male) included in the study had a mean age of 56.2 +/- 15.40 years (range, 17-84 years), and the mean SWV value of the lesions in 13 (39%) cases evaluated benign after a CT scan, histopathological examination, or both 2.18 +/- 0.49 m/s. The mean SWV value of the lesions which were histopathologically diagnosed as malign in 23 (61%) cases was 3.50 +/- 0.69 m/s. (P < 0.001). When the cutoff value was set as 2.47 m/s for the SVW value, sensitivity and specificity were determined to be 97.7%.The present study has shown that transthoracic ultrasound shear wave elastography can be an effective radiological examination method in the benign and malign differentiation of subpleural lesions and has the potential for use in the routine clinical application of transthoracic ultrasound elastography, a noninvasive method for evaluating the malignancy potentials of such lesions.