Browsing by Author "Baran, A.I."

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Case Report: Two Plasmodium Vivax Malaria Cases in the Van Province
(2009) Karahocagil, M.K.; Baran, A.I.; Yaman, G.; Ciçek, M.; Bilici, A.; Binici, I.; Akdeniz, H.
Malaria is an important parasitic infection which is endemic in the Eastern Mediterranean and Southeastern Anatolia regions and sporadic in other regions of Turkey, while Plasmodium vivax is the most common cause. Two patients who were admitted to our hospital in October with complaints of high fever, chills, nausea-vomiting, generalized body pain and fatigue and diagnosed as P. Vivax malaria are presented, because they were two brothers with no history of travel outside of Van city.
A Comparative Perspective on Brucellar, Pyogenic, and Tuberculous Spondylodiscitis
(Verduci Editore s.r.l, 2024) Baran, A.I.; Celik, M.; Arslan, Y.; Incecik, S.; Binici, I.; Toprak, M.; Sunnetcioglu, M.
OBJECTIVE: Non-specific features of spondylodiscitis lead to a delay and challenge in the diagnosis/differential diagnosis/treatment processes, and thus, serious complications may arise. This study aims to compare brucellar, pyogenic, and tuberculous types of spondylodiscitis, considering their demographic, clinical, and laboratory differences. This may provide more rapid management and good outcomes. PATIENTS AND METHODS: A total of 131 patients with infectious spondylodiscitis were included in the study. The patients were divided into brucellar (n=63), pyogenic (n=53), and tuberculous (n=15) types of spondylodiscitis and compared for demographic, clinical, laboratory, and imaging features. RESULTS: Tuberculous spondylodiscitis had higher scores for weight loss, painless palpation, thoracic spine involvement, and psoas abscess formation than other spondylodiscitis. Also, tuberculous spondylodiscitis had higher rates of neurologic deficit and lower rates of lumbar involvement than brucellar spondylodiscitis. Pyogenic spondylodiscitis is more likely to occur in patients who have a history of spine surgery compared to other forms of spondylodiscitis. Also, pyogenic spondylodiscitis had higher rates of fever, erythema, paraspinal abscess, white blood cell (WBC), and erythrocyte sedimentation rate (ESR) than brucellar spondylodiscitis. On the other hand, brucellar spondylodiscitis had higher rates of rural living and sweating than pyogenic spondylodiscitis. CONCLUSIONS: Weight loss, painless palpation, involved thoracic spine, psoas abscess, and neurologic deficit are symptoms favoring tuberculous spondylodiscitis. History of spine surgery, high fever, skin erythema, and paraspinal abscess are findings in favor of pyogenic spondylodiscitis. Rural living, sweating, and involved lumbar spine are symptoms that indicate brucellar spondylodiscitis. These symptoms can be used to distinguish the types of spondylodiscitis. © 2024 Verduci Editore s.r.l. All rights reserved.
Comparison of Carbapenem Resistance Detected by the Bd Phoenix Automated System in Enterobacteriaceae Isolates With E-Test Method
(Modestum LTD, 2022) Celik, M.; Sunnetcioglu, M.; Guducuoglu, H.; Arslan, Y.; Akyuz, S.; Baran, A.I.
Objective: Automatic identification and antimicrobial susceptibility systems are frequently used to identify clinical isolates in hospitalized patients, but mistakes in these systems can lead to potentially devastating treatment failures for patients. Therefore, the ‘‘Centers for Disease Control and Prevention (CDC)’’ recommends confirming all Carbapenem-resistant and low-susceptibility isolates with a different method. The aim of this study is to compare the Carbapenem susceptibility results of isolates reported as Carbapenem-resistant Enterobacteriaceae according to the BD Phoenix 100 automated system with the E-test method. Materials and Methods: The study included 70 strains of Carbapenem-resistant Enterobacteriaceae members which were isolated and grown from several types of clinical samples in the Medical Microbiology Laboratory. Conventional methods (Gram stain, negative oxidase test) and the BD Phoenix 100 automated system were used to identify the isolates. The susceptibility of all strains to imipenem, ertapenem and meropenem was investigated by E-test method. Automated system results and E-test results were compared. Results: The frequency distribution of all isolated bacterial strains comprised K. pneumoniae in 56 (80%) of the samples included in the study. The automated system test results were correlated with the results of the E-test at a rate of 96.1 % for the imipenem-resistant strains, 84.3% for the meropenem-resistant strains, 84.1% for the ertapenem-resistant strains Conclusions: Automated systems are frequently used in microbiology laboratories to identify isolates. However, automated systems can show a high error rate against some antimicrobials. For this reason, comparing the results of automated system test results with tests such as E-test is very important to prevent both treatment failures and inappropriate antibiotic use that may occur on a patient basis. © 2022 by Author/s and Licensed by Modestum.
Complete Recovery From Clinical Rabies: Case Report
(Turkiye Klinikleri, 2013) Karahocagil, M.K.; Akdeniz, H.; Aylan, O.; Sünnetçioǧlu, M.; Ün, H.; Yapici, K.; Baran, A.I.
A 17-year-old male had been bitten by his dog. He was given one dose of rabies vaccine after being bitten. Twenty days after vaccination, he developed complaints of itching and paresthesia at the bite area on his forearm. He was transferred to our department with the preliminary diagnosis of rabies due to his complaints of fever, abdominal pain, dysphagia and difficulty of breathing after 3-5 days. Rabies viral nucleic acid was positive by reverse transcriptase polymeraze chain reaction in the cerebrospinal fluid and saliva samples, and corneal smear was found positive with fluorescence antibody method. Patient's complaints markedly subsided after hospitalization and he was discharged on 66th day with complete recovery. In the literature, complete recovery in patients with clinical rabies is limited to a few cases. In this paper, we present the first case recovering from human clinical rabies, whose diagnosis was confirmed by direct diagnostic methods. © 2013 by Türkiye Klinikleri.
Essential Trace Element Levels in Patients With Cutaneous Anthrax
(Yuzuncu Yil Universitesi Tip Fakultesi, 2023) Binici, I.; Parlak, M.; Sunnetcioglu, M.; Baran, A.I.; Ceylan, M.R.; Kul, A.R.; Huyut, Z.
The causative microorganism in anthrax is Bacillus anthracis and this disease is more common in some regions of Türkiye. Changes in trace elements other than iron in anthrax infection have not been studied. In this study, iron, copper, lead, zi nc, manganese, magnesium, cadmium and cobalt levels were investigated in cases with cutaneous anthrax. Fifteen patients with cutaneous anthrax and 15 healthy individuals wereincluded in the study. The groups were similar to each other in terms of age and gender. Anthrax was diagnosed according to contact status with animals, symptoms, examination, and microbiological results. We performed our study with Atomic Absorption Spectrophotometer (UNICAM-929 spectrophotometer). Serum iron, lead, and cadmium levels were significantly higher in the patients than in the control subjects (p<0.05). Serum magnesium, manganese, zinc, copper, and cobalt levels were significantly lower in the patients than in the control subjects (p<0.05). The copper/zinc molar ratio was not significantly increased in the patients with cutaneous anthrax than in the control subjects. It has been reported that iron, cadmium, and lead levels are low and copper level is high in infectious diseases. But we determined the opposite situation in the patients with cutaneous anthrax. As a result, it can be said that the detection of high lead and cadmium levels in the cell in anthrax disease suppresses the immune system. Also, zinc can be used as a marker for this disease. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Evaluation of Peritonitis Attacks in Patients Applying Peritoneal Dialysis
(Yuzuncu Yil Universitesi Tip Fakultesi, 2023) Baran, A.I.; Karahocagil, M.K.; Soyoral, Y.U.; Mülayim, G.
Peritoneal dialysis is one of the renal replacement therapies used to treat patients with end-stage renal disease. Peritonitis is a common complication of peritoneal dialysis. Although the incidence of peritonitis has decreased, it is still a problem and the most important determinant of hospitalization, mortality, and morbidity. The aim of this study was to evaluate the incidence of peritonitis in peritoneal dialysis patients, compare culture methods, and determine the causative microorganisms and antibiotic susceptibility. Patients who were on the peritoneal dialysis treatment program and developed peritonitis were included in the study. Demographic, clinical, and laboratory data of the cases were recorded. The growth rates of pathogens in the peritoneal fluid, causative microorganisms, and antibiotic susceptibility results were evaluated in the peritonitis cases. During the study, 47 episodes of peritonitis occurred in 28 patients. The mean incidence of peritonitis was 0.57 attacks/patient-year. Growth rates in the blood culture system and solid media were 51% and 46.1%, respectively, and there was no significant difference between them. According to the culture results, 75% were Gram-positive microorganism and the most common pathogens were coagulase-negative staphylococci. In our study, no significant difference was found between inoculation of peritoneal fluid into blood culture bottles and solid media. The most common pathogens were coagulase-negative staphylococci. As methicillin-resistant staphylococci are common, treatment with vancomycin seems appropriate. It was thought that ceftazidime, which is used for gram-negative bacteria, may not be sufficient due to resistance, and studies with more gram-negative cases are needed to evaluate this. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Psychotic Attacks Due To Toxic Neurobrucellosis in Two Adolescent Patients
(Yerkure Tanitim ve Yayincilik, 2014) Ozdemir, O.; Baran, A.I.; Cilingir, V.; Bulut, M.D.; Ozdemir, P.G.; Yilmaz, E.
Brucellosis is a multisystem disease which can present with a broad spectrum of clinical manifestations and complications and affect the central nervous system directly or indirectly. Immunopathologic mechanisms like T-cell mediated cytotoxicity and microglia activation are suggested to play a role in neurobrucellosis. The diagnosis of toxic neurobrucellosis is confirmed by isolation of Brucella organism from blood cultures and/or positive Coombs Wright test and the Standard agglutination test (SAT) in serum when there are no cerebrospinal fluid (CSF) findings. The magnetic resonance imaging (MRI) of brain in patients with neurobrusellosis may show different findings mimicking such neurological diseases as inflammation, white matter changes and vascular involvements and other infectious and inflammatory conditions. Different clinical manifestations of neurobrucellosis have been described including meningitis, meningoencephalitis, myelitis, and psychiatric disorders. It has been indicated in case studies that neurobrucellosis may lead to psychotic disorders. In this study, we present two adolescents who presented with psychotic symptoms due to toxic neurobrucellosis.
Salmonella Ovarian Abscess in a Patient With Systemic Lupus Erythematosus Presented as Acute Abdomen: a Case Report and Review of the Literature
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Baran, A.I.; Sunnetcioglu, M.; Yakan, U.; Batur, A.; Karagoz, E.; Karahocagil, M.K.
A Salmonella ovarian abscess is a rare entity, and is similarly uncommon in cases with Systemic Lupus Erythematosus. To the best of our knowledge, thirty four cases of Salmonella ovarian abscess have been published in the literature, and only four of them were related to Systemic Lupus Eritematosus. Our aim is to review this clinical entity using information from our own experience as well as that from published cases. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.