Browsing by Author "Baskin, Dilges"

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Cytotoxicity and Antibacterial Activity of Polyhedral Oligomeric Silsesquioxane Modified Ti3c2tx Mxene Films
(Nature Portfolio, 2025) Akinay, Yuksel; Karatas, Erkan; Ruzgar, Damla; Akbari, Ali; Baskin, Dilges; Cetin, Tayfun; Topuz, Mehmet
Bioactive antimicrobial films play important roles in various fields, such as biodegradable interfaces, tissue regeneration, and biomedical applications where preventing infection, biocompatibility, and immune rejection are important. In the present study, bioactive POSS-doped Ti3C2Tx MXene filled PLA composite film was prepared using the solution casting method for biomedical applications. The contact angle tests were investigated to reveal the usability of the thin films in biomedical applications. The angle decreased from 85.92 degrees degrees in pure PLA thin films to 72.23 degrees on POSS-doped Ti3C2Tx MXene films. The antibacterial performance, cytotoxicity and cell viability assessments of the prepared films have also been thoroughly investigated. Antibacterial tests revealed that the POSS-doped Ti3C2Tx MXene films effectively inhibited the growth of E. coli and S. aureus by 65.93% and 80.63%, respectively, within 4 h. These inhibition rates were observed as 58.32% and 54.97% for E. coli and S. aureus, respectively, after 24 h. Cytotoxicity assessments demonstrated that PMPs consistently showed higher cell viability due to the combination of POSS and Ti3C2Tx MXene. The obtained results suggest that the POSS-doped Ti3C2Tx MXene film is a promising candidate in cases where bacterial inhibition and high biocompatibility are of critical importance.
Preconcentration and Determination of Copper(Ii) in Water and Tea Infusion Samples Using Hierarchical Mnsb2o6@fe3o4 Nanoparticles and Magnetic Solid Phase Extraction-Faas
(Amer Chemical Soc, 2025) Baskin, Dilges
Heavy metal pollution poses a significant threat to living organisms and requires continuous monitoring of the environmental samples. In this study, novel hierarchical MnSb2O6@Fe3O4 nanoparticles were synthesized and used as adsorbents in magnetic solid-phase extraction (MSPE) of Cu(II). The strong magnetic properties of these nanoparticles enabled rapid and efficient separation from complex matrices, simplifying preconcentration and ensuring high adsorption efficiency. By integration of MSPE with flame atomic absorption spectrometry (FAAS), matrix effects were reduced, detection limits improved, and the cost-effectiveness and simplicity of FAAS were leveraged for Cu(II) analysis in complex samples. The optimized parameters for the MSPE-FAAS method included pH, stirring time and type, eluent volume and type, and adsorbent amount, achieving a correlation coefficient of 0.9991, a limit of detection of 2.1 ngmL-1 and a linear range of 10.0-200 ngmL-1. The developed method enhanced FAAS sensitivity by 48-fold and was successfully applied to wastewater, tap water, and apple tea samples, achieving recoveries of 93-102%. The Cu(II) adsorption capacity of MnSb2O6@Fe3O4 was determined to be 15.2 mgg-1, demonstrating its high efficiency for heavy metal removal. This methodology highlights a robust and efficient approach for preconcentrating trace metals from diverse and complex matrices, combining the advantages of MSPE and FAAS in a practical, cost-effective system.
Spinel ZnFe2O4 Nanoparticles Doped with Ba2 + for High-Performance Cu(II) Extraction via d-SPE-FAAS
(Amer Chemical Soc, 2025) Baskin, Dilges
In this study, a dispersive solid-phase extraction (d-SPE) method was developed and characterized using Ba-doped ZnFe2O4 spinel nanoparticles for the selective preconcentration and determination of Cu(II) ions in environmental- and food-based matrices. The structural features of the nanosorbent were thoroughly investigated using SEM, SEM-EDX, XRD, and FTIR techniques. The integration of Ba2 + into the spinel lattice structure enhanced the adsorbent's surface reactivity, and the material is therefore presented as a high-surface-area spinel sorbent, which contributed to the efficient and selective retention of Cu(II) ions. Following the optimization of extraction parameters (pH 9.0, 40 mg of sorbent, 0.3 mL of HNO3, 60 s vortex for adsorption, and ultrasonic mixing for desorption), quantification was carried out using flame atomic absorption spectrometry (FAAS). The method exhibited excellent analytical performance, achieving a limit of detection (LOD) of 0.67 ng mL- 1, a wide linear dynamic range of 5.0-300 ng mL- 1, and a correlation coefficient (R 2) of 0.9992. The developed d-SPE-FAAS method achieved an LOD improvement factor of 62, along with an enhancement factor of 29 and a classical preconcentration factor of 30. In addition, a Langmuir isotherm study at pH 9.0 indicated a maximum adsorption capacity of 104.2 mg g- 1, confirming the affinity of the Ba-doped ZnFe2O4 sorbent for Cu(II). Applicability of the method was evaluated using real samples, including green tea infusions, tap water, and domestic wastewater obtained from the General Directorate of VASKI (Van Water and Sewerage Administration). Quantitative recoveries ranging from 94% to 106% were obtained in real matrices, demonstrating the method's accuracy and reliability in complex sample compositions. The developed d-SPE-FAAS protocol provides a simple, sensitive, and cost-effective approach for determining trace levels of Cu(II), exhibiting strong potential for routine copper monitoring in both environmental and food-derived samples.