Browsing by Author "Baskin, Dilges"

Now showing 1 - 2 of 2

Cytotoxicity and Antibacterial Activity of Polyhedral Oligomeric Silsesquioxane Modified Ti3c2tx Mxene Films
(Nature Portfolio, 2025) Akinay, Yuksel; Karatas, Erkan; Ruzgar, Damla; Akbari, Ali; Baskin, Dilges; Cetin, Tayfun; Topuz, Mehmet
Bioactive antimicrobial films play important roles in various fields, such as biodegradable interfaces, tissue regeneration, and biomedical applications where preventing infection, biocompatibility, and immune rejection are important. In the present study, bioactive POSS-doped Ti3C2Tx MXene filled PLA composite film was prepared using the solution casting method for biomedical applications. The contact angle tests were investigated to reveal the usability of the thin films in biomedical applications. The angle decreased from 85.92 degrees degrees in pure PLA thin films to 72.23 degrees on POSS-doped Ti3C2Tx MXene films. The antibacterial performance, cytotoxicity and cell viability assessments of the prepared films have also been thoroughly investigated. Antibacterial tests revealed that the POSS-doped Ti3C2Tx MXene films effectively inhibited the growth of E. coli and S. aureus by 65.93% and 80.63%, respectively, within 4 h. These inhibition rates were observed as 58.32% and 54.97% for E. coli and S. aureus, respectively, after 24 h. Cytotoxicity assessments demonstrated that PMPs consistently showed higher cell viability due to the combination of POSS and Ti3C2Tx MXene. The obtained results suggest that the POSS-doped Ti3C2Tx MXene film is a promising candidate in cases where bacterial inhibition and high biocompatibility are of critical importance.
Preconcentration and Determination of Copper(Ii) in Water and Tea Infusion Samples Using Hierarchical Mnsb2o6@fe3o4 Nanoparticles and Magnetic Solid Phase Extraction-Faas
(Amer Chemical Soc, 2025) Baskin, Dilges
Heavy metal pollution poses a significant threat to living organisms and requires continuous monitoring of the environmental samples. In this study, novel hierarchical MnSb2O6@Fe3O4 nanoparticles were synthesized and used as adsorbents in magnetic solid-phase extraction (MSPE) of Cu(II). The strong magnetic properties of these nanoparticles enabled rapid and efficient separation from complex matrices, simplifying preconcentration and ensuring high adsorption efficiency. By integration of MSPE with flame atomic absorption spectrometry (FAAS), matrix effects were reduced, detection limits improved, and the cost-effectiveness and simplicity of FAAS were leveraged for Cu(II) analysis in complex samples. The optimized parameters for the MSPE-FAAS method included pH, stirring time and type, eluent volume and type, and adsorbent amount, achieving a correlation coefficient of 0.9991, a limit of detection of 2.1 ngmL-1 and a linear range of 10.0-200 ngmL-1. The developed method enhanced FAAS sensitivity by 48-fold and was successfully applied to wastewater, tap water, and apple tea samples, achieving recoveries of 93-102%. The Cu(II) adsorption capacity of MnSb2O6@Fe3O4 was determined to be 15.2 mgg-1, demonstrating its high efficiency for heavy metal removal. This methodology highlights a robust and efficient approach for preconcentrating trace metals from diverse and complex matrices, combining the advantages of MSPE and FAAS in a practical, cost-effective system.