Browsing by Author "Bektas, M. Selcuk"

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Burkitt's Lymphoma Causing Acute Pancreatitis in a Child
(Elsevier Science Bv, 2013) Akil, Muhammed; Kaya, Avni; Bektas, M. Selcuk; Aktar, Fesih; Akbayram, Sinan; Bilici, Salim; Beyazal, Mehmet
A 8-year-old boy admitted with abdominal pain, fever and vomiting for the previous 10 days. Sensitivity was detected in the epigastric area. There was not defense and rebond. Aspartate aminotransferase was 106 U/L, alanine aminotransferase 25 U/L, alkaline phosphatase 311 U/L, blood amylase level 748 U/L, blood lipase level 391 U/L. In thoracic CT, soft tissue with smooth contours measuring 32 mmx28 mm was identified in the posterior mediastinum. Bone marrow aspiration biopsy was normal. A mass specimen obtained from the duodenum endoscopic biopsy. This specimen was diffuse staining by leukocyte common antigen, CD10 and CD20. The patient was diagnosed with acute pancreatitis associated with stage 3 duodenal Burkitt's lymphoma. Modified LMB-98 was initiated. Burkitt's lymphoma may rarely cause acute pancreatitis.
A Case of Acute Disseminated Encephalomyelitis Presented With Transvers Myelitis
(Turkish Pediatrics Assoc, 2010) Kaya, Avni; Ozkan, Mustafa; Bektas, M. Selcuk; Acikgoz, Mehmet; Temel, Hayrettin; Sal, Ertan; Caksen, Huseyin
Acute disseminated encephalomyelitis is an inflammatory and demyelinating disorder of central nervous system. A 9-year-old male was admitted with unable to walk, non-sensation of legs, urinary incontinence and encopresis for 2 days. On physical examination, muscle strength was 5/5 on upper extremities and 1/5 on lower extremities. Loss of pain, temperature and touch sensation was present on both lower extremities, reaches to T8 level. On spinal magnetic resonance imaging, diffuse hyperintensity from C3 to conus medullaris was detected. While electromyography was consistent with polyradiculoneuritis, magnetic resonance imaging findings were concordant with acute disseminated encephalomyelitis. On account of this case, we would like to emphasize that acute disseminated encephalomyelitis should be considered in patients presented with transverse myelitis; therefore, in addition to spinal magnetic resonance imaging, cranial magnetic resonance imaging should be examined in these patients. (Turk Arch Ped 2010; 45: 299-302)
Clinical Findings in Children With Cutaneous Anthrax in Eastern Turkey
(Wiley, 2010) Akbayram, Sinan; Dogan, Murat; Akgun, Cihangir; Peker, Erdal; Bektas, M. Selcuk; Kaya, Avni; Oner, Ahmet Faiko
Anthrax is a zoonosis produced by Bacillus anthracis. The aim of this study was to evaluate the clinical findings, therapy, and outcome in children with cutaneous anthrax (CA). Data on age, gender, occupation, clinical symptoms and findings, location and type of lesions, clinical history, laboratory findings, treatment, and outcome were recorded from patients' medical records, retrospectively. The study included 65 patients between 1 month and 18 years old (9.0 +/- 4.0 years), 37 patients (56.9%) were male and 28 (43.1%) were female. Most of the patients (89.1%) were admitted in summer and autumn (p < 0.001). Of the 65 patients, 20 patients (30.8%) had received antibiotherapy before admission to our hospital. All patients except one had a contact history with infected animals. A 1-month-old patient had a contact history with his mother who had CA. On clinical examination, anthrax edema was noted in 36 (55.3%) patients, anthrax pustule in 27 (41.5%), and anthrax edema and anthrax pustule in two (3%) patients. Gram staining and culture was positive for B. anthracis in 35 (53.8%) patients, and only Gram staining was positive in 10 (15.4%) patients. In the remaining 20 (30.8%) patients, the diagnosis was made by clinical findings. Because the anthrax outbreak in Turkey was associated with slaughtering or milking of ill cows, sheep, or goats, and handling raw meat without taking any protective measures, persons in the community must be educated about using personal protective equipment during slaughtering of animals and handling of meat and skins.
Dyspnea Associated With Vocal Cord Paralysis and Type-2 Chiari Malformation
(Modestum Ltd, 2013) Ceylan, Abdullah; Aktar, Fesih; Karaman, Kamuran; Bektas, M. Selcuk; Kaya, Avni; Caken, Hueyin
The etiology of vocal cord paralysis is highly variable. Neurological, birth trauma, surgical procedure and idiopathic are notable causes. Clinical findings are different according to type of paralysis. Vocal cord paralysis can be seen unilateral or bilateral. Bilateral vocal cord paralysis are more severe clinical findings than according to unilateral paralysis. We report a 9-month child. He was admitted to hospital with stridor and cyanosis He was diagnosed Chiari malformation type 2 and bilateral vocal cord paralysis. Chiari malformation type 2 related vocal cord paralysis can severely respiratory failure.
Infantile Masturbation in Monozygotic Twins
(Wiley-blackwell, 2012) Kaya, Avni; Taskin, Gokmen A.; Okur, Mesut; Bektas, M. Selcuk; Caksen, Huseyin
The Spectrum of Mefv Gene Mutations and Genotypes in Van Province, the Eastern Region of Turkey, and Report of a Novel Mutation (R361t)
(Elsevier, 2015) Coskun, Salih; Ustyol, Lokman; Bayram, Yasemin; Bektas, M. Selcuk; Gulsen, Suleyman; Cim, Abdullah; Savas, Didem
Familial Mediterranean fever (FMF) is the most common hereditary inflammatory periodic disease, characterized by recurrent episodes of fever and abdominal pain, synovitis, and pleuritis. The aim of this study was to determine the frequency and distribution of Mediterranean fever (MEFV) gene mutations in Van province of Eastern Anatolia and to compare them with the other studies from various regions of Turkey. Therefore, we retrospectively evaluated MEFV gene mutations in 1058 pediatric patients with suspected FMF. The MEW gene mutations were investigated using Sanger sequencing and the multiplex minisequencing technique. We identified 37 different genotypes and 16 different mutations. The four most common mutations and allelic frequencies were M694V (36.50%), E148Q (32.77%), V726A (14.09%), and M694I (4.41%). M694V was the most common mutation, and the M694I frequency was found to be higher compared to studies from other regions of Turkey. In addition, we identified a novel missense mutation (R361T, c.1082G>C) in exon 3 of the MEW gene in a 12-year-old boy, who had a typical FMF phenotype. In conclusion, this study evaluated the distribution of MEFV gene mutations in children with FMF as the first study conducted in Van province, Eastern Anatolia. (C) 2015 Elsevier B.V. All rights reserved.