Browsing by Author "Besalti, Ö"

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Comparative Study of Discolysis and Disc Fenestration in Dogs
(Scientific Technical Research Council Turkey, 1999) Besalti, Ö; Özak, A; Akin, F; Gülbahar, MY; Bumin, A
Postoperative clinical, histopathological and radiological findings were evaluated for disc fenestration, open discolysis (chymopapain) and percutan discolysis which had been performed on three groups of dogs, each group containing 6 healthy mongrels of different ages, sexes and breeds. The degrees of intervertebral space narrowing were classified as mild, medium and severe according to postoperative radiological examinations. Sections which were prepared from intervertebral areas which had been operated on, were investigated histopathologically, It was considered that discolysis might be cost effective on type-2 disc diseases, cases without advanced paralysis and cases requiring prophylactic disc fenestration, According to clinical examination results neurological disorders were not observed in the groups with disc fenestration or discolysis. Radiological and hisyopathological findings with respect to disc fenestration were more uniform than in the group which had undergone discolysis.
Splenic Hemangiosarcoma With Abdominal Dissemination in a Dog
(Scientific Technical Research Council Turkey, 1998) Gülbahar, MY; Güvenç, T; Besalti, Ö
A case of spontaneosly ruptured splenic hemangiosarcoma with abdominal dissemination in a 12-year-old male German shepherd dog is described. At necropsy, a ruptured tumor mass was seen in the ventral region of the Visceral surface of the spleen, and disseminated tumor masses were seen throughout the peritoneal cavity. Histologically, in both the primary tumor mass and disseminated tumor masses, atypical endothelial cells lining vascular spaces as small clefts or as cavernous channels were observed. Some immunological properties of tumor cells were determined for endothelial cell markers (factor VII-related antigen=von Willebrand's factor [vWf] and CD31 antigen), mesenchymal tissue marker (vimentin) and pericyte-smooth muscle marker (a-smooth muscle actin [alpha-SMA]). Tumor cells were positive for CD31, vimentin and a-SMA, whereas they were negative for vWf. According to morphological and immunohistochemical results, this case was diagnosed as hemangiosarcoma arising from the spleen with abdominal dissemination.