Browsing by Author "Besiroglu, L"

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The Assessment of Obsessive-Compulsive Symptoms
(Turkiye Sinir ve Ruh Sagligi dernegi, 2005) Besiroglu, L; Agargün, MY; Boysan, M; Eryonucu, B; Gülec, M; Selvi, Y
Objective: We examined the reliability and validity of the 60-and 41-item versions of the Padua Inventory (PI and PI-R) which were developed to assess the frequency and severity of obsessive-compulsive symptoms, in a Turkish population. Method: The sample consisted of 43 OCD patients, 30 non-OCD patients with other anxiety disorders, 30 nonobsessional depressed patients, 76 healthy adults, and 181 undergraduate students. We investigated internal consistency, test-retest reliability, and factor structure, concurrent and discriminant validity. Results: Psychometric analyses showed that both the original PI and PI-R had a high internal consistency and test-retest reliability. While principal factor analysis of the 41 items revealed six factors that are consistent with the PI-R, the factor structure of the original scale was not confirmed. All the subcales and total scores for both instruments were significantly correlated with the Yale-Brown scores except for the impulses subscale. There were significant differences between OCD patients and nonclinical samples in all total and subscale scores for both instruments. OCD patients scored significantly higher on the total, contamination/washing and checking subscales for both instruments than nonobsessional anxious, and depressed patients. While OCD patients scored significantly higher on the PI-R rumination scale than nonobsessional anxious patients, their PI impaired control subscale score was not different from that of the other clinical groups. Conclusions: The Turkish version of the PI has appropriate reliability and validity for assessing the frequency and severity of obsessive-compulsive symptoms.
A Discrimination Based on Autogenous Versus Reactive Obsessions in Obsessive-Compulsive Disorder and Related Clinical Manifestations
(M B L Communications, inc, 2006) Besiroglu, L; Agargun, MY; Ozbebit, Z; Aydin, A
Introduction: Although putative subtypes of obsessive-compulsive disorder (OCD) have been gradually more recognized, there is no generally accepted subtype discrimination. It has been suggested that autogenous and reactive obsessions stem from different cognitive process. This study aimed to assess existence of gender, age at onset of illness, and comorbidity differences in OCD patients suffering from autogenous and reactive obsessions. Methods: The medical records of 177 OCD patients were evaluated retrospectively for gender, age at onset, comorbid diagnoses, and predisposing life events. Obsessions and compulsions were coded according to theYale-Brown Obsessive-Compulsive Scale. All patients were grouped as the patients with autogenous (autogenous group [AG] n=32), reactive (reactive group [RG] n=77) and mixed obsessions (mixed group [MG] n=68). Results: AG patients were significantly more likely to be male, compared with the RG and MG patients. They also had significantly later onset of illness. Dissociative disorders were less common among AG patients compared with the other groups. Conclusion: Results suggest that the discrimination between autogenous and reactive obsessions are not only based on their development and maintenance mechanism through different cognitive process but that there also clinical manifestations of this discrimination.
Nightmares and Terminal Insomnia in Depressed Patients With and Without Melancholic Features
(Elsevier Ireland Ltd, 2005) Besiroglu, L; Agargun, MY; Inci, R
To investigate the relationship between nightmares and melancholic features (MF) in depression, we compared depressed patients with and without MF (n=82 and n=75, respectively) regarding the presence of nightmares. Nightmares were significantly more frequent in patients with ME Depressed mood in the morning may be related to negative dream content. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
The Predictors of Health Care Seeking Behavior in Obsessive-Compulsive Disorder
(W B Saunders Co-elsevier inc, 2004) Besiroglu, L; Çilli, AS; Askin, R
A majority of individuals with obsessive-compulsive disorder (OCD) do not seek health care. To better understand why not, health care-seekers (HCS) with OCD (n = 25) were compared with non-health care-seekers (NHCS) with OCD (n = 23) regarding their sociodemographic variables, symptom severity, types of obsessions and compulsions, 'insight degree, comorbid diagnosis, and quality-of-life (QOL) level. There was no significant difference for sociodemographic characteristics between the groups. NHCS scored significantly lower on a measure of illness severity than HCS. The NHCS group had significantly poorer insight degree than the HCS group. Aggressive and religious obsessions were significantly less identified in the NHCS group compared to the HCS group. NHCS were significantly less likely to have comorbid diagnosis than HCS. The NHCS group reported significantly worse levels of QOL in psychological health and level of independence domains. To identify the predictors of health care seeking behavior, probable variables were entered in a logistic regression model. Insight degree and level of independence emerged as the predictors of health care seeking. Our results suggest that health care seeking behavior in OCD is associated with the individuals' ability to recognize their symptoms as a disorder and subjective interpretation regarding the impact of OCD on their level of independence. Results of the present study extend findings of two recent studies that have investigated factors related to health care seeking in OCD. (C) 2004 Elsevier Inc. All rights reserved.
Serum Lipid Levels, Suicidality, and Panic Disorder
(W B Saunders Co, 2004) Özer, ÖA; Kutanis, R; Agargun, MY; Besiroglu, L; Bal, AC; Selvi, Y; Kara, H
Although the effects of serum total cholesterol and other lipids have been implicated as a predictor of suicidal behavior in major depression, the role of cholesterol level on suicide risk for panic disorder patients is not considered as a biological marker in the literature. In this study, we examined the relationship of suicidality with serum cholesterol concentration in panic disorder. The subjects of the study were 10 suicidal panic disorder patients, 19 nonsuicidal panic disorder patients, and 15 normal control subjects. The suicidal patients with panic disorder had lower serum total cholesterol and low-density lipoprotein (LDL) levels than normal control subjects. These findings suggest that there may be an association between suicidality and low serum cholesterol levels in panic disorder. We also discuss the possible role of serotonin in the brain in the relationship of suicidal behavior or ideation with low cholesterol concentration in panic disorder patients, and 15 normal control subjects. Thesuicidal patients with panic disorder had lower serum total cholesterol and low-density lipoprotein (LDL) levels than normal control subjects. These findings suggest that there may be an association between suicidality and low serum cholesterol levels in panic disorder. We also discuss the possible role of serotonin in the brain in the relationship of suicidal behavior or ideation with low cholesterol concentration in panic disorder. (C) 2004 Elsevier Inc. All rights reserved.
Sleep and Suicidality
(Oxford Univ Press inc, 2005) Agargun, MY; Besiroglu, L