Browsing by Author "Besiroglu, Luetfullah"

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Assessment of Hierarchical Factor Structure, Reliability and Validity of Penn State Worry Questionnaire Turkish Version
(Kure Iletisim Grubu A S, 2008) Boysan, Murat; Keskin, Siddik; Besiroglu, Luetfullah
Objective: Excessive, pervasive, and uncontrollable worry are included in the diagnostic criteria of generalized anxiety disorder. Pathological worry is thought to be the cognitive component of anxiety and to be used as a moladaptive defense mechanism However, negative outcomes of pervasive and uncontrollable worry are not restricted to anxiety disorders alone, A growing number of studies point out that pathological worry is associated with panic disorder, obsessive compulsive disorder, depression, sleep disorders and psychotic disorders, Also pervasive and uncontrollable worry is significantly correlated with medical problems such as heart diseases, diabetes and cancer. In order to assess levels of worry several instruments were developed; for example The Worry Domains Questionnaire (Tallis et at 19921, The Anxious Thoughts Inventory (Wells 1994), The Meta Worry Questionnaire (Wells 1995), The Meta Cognitions Questionnaire -30 (Wells, Cartwright-Hatton, 2004). However, Penn State Worry Questionnaire (PSWQ) is the most commonly utilized measure on assessing pathological worry, This self-report measure has been translated into many languages. The measure has shown excellent psychometric properties in studies among non-clinical and clinical populations. The aim of this study was to translate the instrument into Turkish and to assess the factor structure of the instrument in a Turkish sample. Method: Sample of the study comprised of 651 undergraduates of the Yuzuncu Yil University. Factor structures were obtained by using principal components analysis The Penn State Worry Scale, The Beck Depression Inventory, The Beck Anxiety Inventory, The Rosenberg Self-Esteem Scale, and General Self Efficacy Scale were administered. Model fitness of the factor structure was evaluated by using structural equation technique The Schmid-Leimon transformation was performed to provide higher order factor loadings. PSWQ total and sub-scale scores were correlated with depression, anxiety, self-esteem, and self-efficacy in order to assess convergent validity of the measure, Comparisons between correlations were carried out using the Z test. Results: Convergent validity between PSWQ total scores and other psychological variables was compatible with previous studies. Correlation between PSWQ total scores and Beck Depression Inventory was r = 0.45. PSWQ significantly correlated with Beck Anxiety Inventory r = 0.46. Correlation between PSWQ and Rosenberg Self Esteem Scale was r = -0.36. Inner consistency of the measure was 0.88. It was found that PSWQ consisted of General Worry, Excessive/Uncontrollable Worry, and Absence of Worry factors, a three factor hierarchical structure. Discussion: PSWQ is a valid and reliable measure in assessing pathological worry in a Turkish sample. Results have shown that factor structure of the measure obtained in a Turkish sample is consistent with international samples Translation of the measure into Turkish may contribute to assessing possible outcomes of pathological worry, which is thought to play an important role in the onset of psychopathology, among Turkish sample.
Associations Between the Levels of Depression and the Sense of Limitedness: a Psychometric Analysis
(Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2008) Boysan, Murat; Besiroglu, Luetfullah; Kara, Hayrettin; Kayri, Murat; Keskin, Siddik
Objective: The sense of limitedness is a cognitive orientation that represents individuals' limited, fixed, and interdependent attributions about interpersonal relations and life opportunities, which are sources for growth and motivation. The cognition is thought as a risk factor for onset of depression. The aim of this study was to assess the relationship between the sense of limitedness, depression, and other risk factors for depression in the study. Methods: The Limitedness Schemas Questionnaire was developed to assess the level of limitedness orientation as a cognitive style. Data were collected from 767 university students and 142 adult subjects via the Limitedness Schemas Questionnaire, the Beck Depression Inventory, the Beck Depression Inventory, the Rosenberg Self-Esteem Scale, and the Learned Helplessness Scale. Subscales of the Limitedness Schemas Questionnaire were obtained by using principle components analysis. Correlations between psychological variables and sense of limitedness were used for evaluation of convergent validity. Results: The Limitedness Schemas Questionnaire had an inner consistency of 0.89. A four-factor structure was obtained for the 30-item Limitedness Schemas Questionnaire. Total and subscale scores of Limitedness Schemas Questionnaire were significantly correlated with depression, anxiety, self esteem, and learned helplessness. Discussion: Results have shown that the Limitedness Schemas Questionnaire is a reliable and valid construct. Results also revealed that sense of limitedness may be a cognitive vulnerability factor for both depression and for other types of psychopathology. (Anatolian Journal of Psychiatry 2008; 9: 191-196)
Associations of Dysfunctional Interpersonal Schemas With Obsessive-Compulsive and Dissociative Symptoms in University Students
(Galenos Yayincilik, 2010) Boysan, Murat; Besiroglu, Luetfullah; Kalafat, Temel; Kagan, Muecahit; Ates, Can
Objective: The aim of the study was to explore associations between obsessive-compulsive symptoms, dissociation, and dysfunctional limitedness schemas. Methods: Data were collected from 322 undergraduates. The sample was composed of 159 females (49.38%) and 163 males (50.62%). The Dissociative Experiences Scale (DES), the Padua Inventory (PI), the Clark-Beck Obsessive-Compulsive Inventory (CBOCI), the Limitedness Schemas Questionnaire (LSQ), the Beck Anxiety Inventory (BAI), and the Beck Depression Inventory (BDI) were administered to the subjects. Hierarchical regression analyses were performed after controlling for age, gender, anxiety and depression. Results: Interpersonal limitedness schemas significantly predicted higher scores on dissociation and obsessive-compulsive symptoms after controlling for age, gender, anxiety and depression. Perceived interconnectedness was also associated with obsessive impulses and checking behavior as well. Conclusion: Interpersonal negativistic schemas, as a cognitive vulnerability factor, may be important in the emergence and maintenance of obsessive-compulsive symptoms and dissociation. Results are discussed under the theoretical approaches concerning dissociation and obsessive-compulsive symptoms. (Archives of Neuropsychiatry 2010; 47: 9-14)
Childhood Traumatic Experiences, Dissociation and Obsessive-Compulsive Symptoms in Non-Clinical Samples
(Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2008) Celikel, Hatice; Besiroglu, Luetfullah
Objective: The childhood traumatic experiences may have a triggering role in the beginning of obsessive-compulsive symptoms. Besides, dissociation that is related to the childhood traumatic experiences may also be influential on obsessive-compulsive symptoms. This study has been carried out to determine the relation between childhood traumatic experiences, dissociative experiences and obsessive-compulsive symptoms among university students. Methods: The sample of the study is consisted of 277 representative university students, 139 of whom are female and 138 of whom are male. In order to collect the data, the participants were applied Dissociative Experiences Scale (DES), Childhood Trauma Questionnaire (CTQ-53), Padua Inventory (PI) and White Bear Suppression Inventory (WBSI). Results: When the correlational coefficients found between OC symptoms and childhood traumatic experiences are generally considered, they are found lower than dissociations and OC symptoms. As the result of regression analyses, both traumatic and pathological dissociation points are found tohave less relational to OC symptoms, whereas non-pathological dissociation (absorption) appeared to be in more meaningful relation with OC symptoms. Discussion: These results indicate that non-pathological dissociation has more relationship to OC symptoms than childhood traumatic experiences and pathological dissociation which is an expected result of the trauma.
Mental Health Literacy Concerning Categories of Obsessive-Compulsive Symptoms
(Turkish Neuropsychiatry Assoc-turk Noropsikiyatri dernegi, 2010) Besiroglu, Luetfullah; Akman, Nevzat; Selvi, Yavuz; Aydin, Adem; Boysan, Murat; Ozbebit, Ozguer
Objective: Despite the considerable distress and disability, many obsessive-compulsive disorder (OCD) sufferers usually are not inclined to seek health care due to their poor mental health literacy. The concept of "mental health literacy" is defined as the knowledge, beliefs, and attitudes related to the recognition, management, and prevention of psychiatric disorders. We aimed to investigate mental health literacy concerning different obsessive-compulsive symptoms in a community sample. Methods: The sample consisted of 376 healthy subjects. They were given vignettes describing four cases with different symptom categories of obsessive-compulsive disorders (aggressive obsessions and related compulsions, contamination obsessions and related compulsions, religious obsessions and related compulsions, and ordering-arranging-counting obsessions and related compulsions), based on factor analytic studies. Each vignette was followed by 17 questions about problem recognition, causes, care alternatives and stigma-shame. Results: When comparing the different categories, the participants were significantly more likely to rate the aggressive category as an abnormal condition and to associate it with stressful life events; to rate the aggressive and contamination categories as signs of mental disorder and to associate them with medical causes; and to rate religious category as a religious problem, and seeing a religious healer was the preferred care-seeking behavior. Significantly more participants noted that they would hide aggressive and religious category symptoms from their family members and co-workers, and would feel shame. Participants were more likely to hold stigmatizing attitudes towards persons with symptoms of contamination category. Conclusion: These findings suggest that the presence of different phenomenological characteristics of OCD may influence health care-seeking behavior in complex ways, due to mental health literacy. While social environment provides a bearable, acceptable or suitable atmosphere for a number of psychiatric problems, some problems might be less tolerated in the sociocultural context. (Archives of Neuropsychiatry 2010; 47: 133-8)
Psychopharmacological Treatment and Quality of Life in Obsessive Compulsive Disorder
(Turkiye Sinir ve Ruh Sagligi dernegi, 2008) Besiroglu, Luetfullah; Uguz, Faruk; Yilmaz, Ertan; Agarun, Mehmet Yucel; Askin, Ruestem; Aydin, Adem
Objective: Obsessive compulsive disorder (OCD) is on illness that considerably influences the family, academic, occupational and social functioning of patients. In this study, we aimed to investigate the impact of psychopharmacological treatment on quality of life in patients with OCD. Method: Using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Hamilton Depression Rating Scale (HDRS) and the World Health Organization Quality of Life Measurement Instrument Short Form, Turkish Version (WHOQOL-Bref TR) we assessed 53 patients who met the DSM-IV criteria for OCD to establish baseline values. The patients were consecutively assigned to receive either sertraline (100-200 mg/day), fluvoxamine (200-300 mg/day) or paroxetine (40-80 mg/day). We reassessed 36 (68%) of the initial group after 12 weeks. Results: The scores of obsession, compulsion and depression severity at follow-up were significantly lower than those of baseline scores. There is no significant difference between the pre and post-treatment quality of life domain scores. While psychological health scores at follow-up was significantly associated with baseline HDRS scores (r=-0.35, p<0.05), social relationship scores at follow-up was significantly associated with baseline social relationship scores (r=0.63, p<0.001) and compulsion scores (r=-0.37, p<0.05). Regression analyses revealed that social relationship scores at follow-up was associated with baseline compulsion severity whereas other follow-up quality of life domain scores were not predicted by any baseline variable. Conclusions: Clinical viewpoint and objective evaluations should be essential in the evaluation of treatment outcome, and quality of life researches may be important complement to clinical researches.
Therapeutic Response To Plasmapheresis in Four Cases With Obsessive-Compulsive Disorder and Tic Disorder Triggered by Streptococcal Infections
(Turkiye Sinir ve Ruh Sagligi dernegi, 2007) Besiroglu, Luetfullah; Agargun, Mehemet Yuecel; Oezbebit, Oezguer; Soezen, Mehmet; Dilek, Imdat; Guelec, Mustafa
The acronym PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) has been assigned to a subgroup of patients experiencing pediatric onset obsessive-compulsive symptoms and tics as a result of autoimmune response to group A B-hemolytic streptococcal infection. It has been hypothesized that an immune process initiated by infection affects the basal ganglia and causes neuropsychiatric symptoms. In cases with severe neuropsychiatric symptoms, the use of treatment strategies that interrupt the autoimmune process responsible for the pathogenesis of PANDAS, such as therapeutic plasmapheresis or intravenous immunoglobulin, has been proposed. In this paper we discuss the effect of plasmapheresis treatment in 4 adult cases of obsessive-compulsive disorder and tic disorder triggered by streptococcal infections.