Browsing by Author "Binici, I."

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Case Report: Two Plasmodium Vivax Malaria Cases in the Van Province
(2009) Karahocagil, M.K.; Baran, A.I.; Yaman, G.; Ciçek, M.; Bilici, A.; Binici, I.; Akdeniz, H.
Malaria is an important parasitic infection which is endemic in the Eastern Mediterranean and Southeastern Anatolia regions and sporadic in other regions of Turkey, while Plasmodium vivax is the most common cause. Two patients who were admitted to our hospital in October with complaints of high fever, chills, nausea-vomiting, generalized body pain and fatigue and diagnosed as P. Vivax malaria are presented, because they were two brothers with no history of travel outside of Van city.
A Comparative Perspective on Brucellar, Pyogenic, and Tuberculous Spondylodiscitis
(Verduci Editore s.r.l, 2024) Baran, A.I.; Celik, M.; Arslan, Y.; Incecik, S.; Binici, I.; Toprak, M.; Sunnetcioglu, M.
OBJECTIVE: Non-specific features of spondylodiscitis lead to a delay and challenge in the diagnosis/differential diagnosis/treatment processes, and thus, serious complications may arise. This study aims to compare brucellar, pyogenic, and tuberculous types of spondylodiscitis, considering their demographic, clinical, and laboratory differences. This may provide more rapid management and good outcomes. PATIENTS AND METHODS: A total of 131 patients with infectious spondylodiscitis were included in the study. The patients were divided into brucellar (n=63), pyogenic (n=53), and tuberculous (n=15) types of spondylodiscitis and compared for demographic, clinical, laboratory, and imaging features. RESULTS: Tuberculous spondylodiscitis had higher scores for weight loss, painless palpation, thoracic spine involvement, and psoas abscess formation than other spondylodiscitis. Also, tuberculous spondylodiscitis had higher rates of neurologic deficit and lower rates of lumbar involvement than brucellar spondylodiscitis. Pyogenic spondylodiscitis is more likely to occur in patients who have a history of spine surgery compared to other forms of spondylodiscitis. Also, pyogenic spondylodiscitis had higher rates of fever, erythema, paraspinal abscess, white blood cell (WBC), and erythrocyte sedimentation rate (ESR) than brucellar spondylodiscitis. On the other hand, brucellar spondylodiscitis had higher rates of rural living and sweating than pyogenic spondylodiscitis. CONCLUSIONS: Weight loss, painless palpation, involved thoracic spine, psoas abscess, and neurologic deficit are symptoms favoring tuberculous spondylodiscitis. History of spine surgery, high fever, skin erythema, and paraspinal abscess are findings in favor of pyogenic spondylodiscitis. Rural living, sweating, and involved lumbar spine are symptoms that indicate brucellar spondylodiscitis. These symptoms can be used to distinguish the types of spondylodiscitis. © 2024 Verduci Editore s.r.l. All rights reserved.
Essential Trace Element Levels in Patients With Cutaneous Anthrax
(Yuzuncu Yil Universitesi Tip Fakultesi, 2023) Binici, I.; Parlak, M.; Sunnetcioglu, M.; Baran, A.I.; Ceylan, M.R.; Kul, A.R.; Huyut, Z.
The causative microorganism in anthrax is Bacillus anthracis and this disease is more common in some regions of Türkiye. Changes in trace elements other than iron in anthrax infection have not been studied. In this study, iron, copper, lead, zi nc, manganese, magnesium, cadmium and cobalt levels were investigated in cases with cutaneous anthrax. Fifteen patients with cutaneous anthrax and 15 healthy individuals wereincluded in the study. The groups were similar to each other in terms of age and gender. Anthrax was diagnosed according to contact status with animals, symptoms, examination, and microbiological results. We performed our study with Atomic Absorption Spectrophotometer (UNICAM-929 spectrophotometer). Serum iron, lead, and cadmium levels were significantly higher in the patients than in the control subjects (p<0.05). Serum magnesium, manganese, zinc, copper, and cobalt levels were significantly lower in the patients than in the control subjects (p<0.05). The copper/zinc molar ratio was not significantly increased in the patients with cutaneous anthrax than in the control subjects. It has been reported that iron, cadmium, and lead levels are low and copper level is high in infectious diseases. But we determined the opposite situation in the patients with cutaneous anthrax. As a result, it can be said that the detection of high lead and cadmium levels in the cell in anthrax disease suppresses the immune system. Also, zinc can be used as a marker for this disease. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Investigation of the Predictive Value of Amino Acids for Tuberculous Meningitis, Aseptic Meningitis and Bacterial Meningitis
(Yuzuncu Yil Universitesi Tip Fakultesi, 2023) Binici, I.; Huyut, Z.; Alp, H.H.; Akbay, H.I.; Karsen, H.; Parlak, M.; Akmeşe, Ş.
In our study, we aimed to detect amino acid changes, if any, by comparing the levels of amino acids in cerebrospinal fluid (CSF) samples of patients with aseptic, bacterial, and tuberculous meningitis and control groups. Patients diagnosed with aseptic meningitis (n=41), tuberculous meningitis (n=21), bacterial meningitis (n=41) and a control group consisting of 64 individuals with similar gender and age characteristics were included in the study. 2 mL of cerebrospinal fluid specimens were obtained from all patients and control group and sto red at-80 °C until the study day. The amino acid measurements were performed using commercially available liquid chromatography-tandem mass spectrometry method (LC-MS / MS) kits. When we investigated amino acids levels in all groups, the levels of 1-methyl histidine, alanine, asparagine, histidine, isoleucine, lysine, methionine, norvaline, ornithine, phenylalanine, proline, sarcosine, threonine, tyrosine, valine in the aseptic, tuberculosis and bacterial meningitis groups were statistically higher than t hose of the control group. The levels of all amino acids except cystine, glutamic acid, homo-citrulline, and taurine in the patients with aseptic meningitis were statistically significantly higher than in the control group. The levels of all amino acids ex cept homocitrulline, and tryptophan were statistically significantly higher in the patient group with tuberculous meningitis than in the control group. The levels of all amino acids except glutamic acid were statistically significantly higher in the patient group with bacterial meningitis than in the control group. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.