Browsing by Author "Bulan, K."

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How Appropriate Are the Lengths of Syringe Needles Used for Subcutaneous Injections To the Children at School Age
(Univ West indies Faculty Medical Sciences, 2021) Kaba, S.; Dogan, M.; Bulan, K.; Yavuz, A.; Bora, A.; Didin, M.; Kocaman, S.
Objectives: To define the normal ranges of the thicknesses of the skin and subcutaneous tissues via ultrasonography, and determine whether the current syringe needle-lengths used for the subcutaneous injections were appropriate. Methods: The thicknesses of the skin and subcutaneous tissues of 2244 students were measured at the left arm using ultrasonography. The patients were divided into three groups based on their age: 6-8, 9-12 and 13-17 years. Results: The thicknesses of the skin, subcutaneous tissue and skin-subcutaneous tissue were found to be positively correlated with their age, body mass index (BMI) and body surface area. All these were observed to be gender related. There was the possibility to make intramuscular injections for 50%, 25% and 25% of boys within the age groups of 6-8, 9-12 and 13-17 years, respectively. For girls, the risk of intramuscular injection was 25% for all the age groups. Conclusion: The study showed that the skin and skin-subcutaneous tissue thicknesses varied as a function of the patients' age, gender, BMIs and body surface areas.
Oxidant/Antioxidant System Markers and Trace Element Levels in Children With Nutritional Rickets
(2012) Doǧan, M.; Cesur, Y.; Doǧan, S.Z.; Kaba, S.; Bulan, K.; Cemek, M.
Objective: To determine the oxidative stress and trace element levels in vivo in patients with nutritional rachitism associated with vitamin D deficiency. Materials and method: A total of 30 patients, 18 males and 12 females, were included in the study. Age, sex, medical history, vital, and physical examination findings of each patient documented at presentation were recorded. Serum calcium, phosphorus, alkaline phosphatase, parathormone, and 25-OH vitamin D levels, as well as oxidant and antioxidant system parameters and trace element levels were studied. After being diagnosed with rachitism, the patients were administered a single dose of 300,000 IU vitamin D by intramuscular injection. The same analyses were repeated post-treatment. Thirty children with normal anthropometric measurements were included as the control group. The analyses described above were performed only once for the control group. Results: Serum calcium, phosphorus, alkaline phosphatase, parathormone, and 25-OH vitamin D levels were different between the controls and children in the patient group (p <0.001). Analysis of trace element levels demonstrated markedly lower pretreatment zinc levels for the patient group compared to the controls, with a statistically significant difference (p =0.001). Comparison of pretreatment oxidant and antioxidant system markers between the patient and control groups demonstrated higher values for vitamin C, β-carotene, reduced glutathione, and superoxide dismutase in the control group, whereas MDA was higher in the patient group. Conclusion: The present study demonstrated increased oxidative stress, reduced antioxidant defence system in patients with nutritional rachitism, with reduced oxidative stress and a pronounced improvement in the antioxidant system with vitamin D treatment.
Pierre Robin Sequence With H-Type Tracheoesophageal Fistula and Congenital Heart Disease
(2013) Demir, N.; Peker, E.; Tuncer, O.; Üstyol, L.; Bulan, K.
Pierre Robin sequence (PRs) is a congenital disease characterized by micrognathia, cleft palate, glossoptosis and a wide range of other anomalies. The treatment of patients with PRs may be problematic due to the varying anomalies and high mortality rate. In this case report, a 1-day-old newborn with micrognathia, cleft lip and palate, glossoptosis, a membranous ventricular septal defect and an H-type tracheoesophageal fistula has been evaluated and discussed considering the current literature. To the best of our knowledge, the coexistence of PRs with a membranous ventricular septal defect and H-type tracheoesophageal fistula has not been previously described. © 2013 Elsevier Ireland Ltd.
A Study on the Effects of Pica and Iron-Deficiency Anemia on Oxidative Stress, Antioxidant Capacity and Trace Elements
(Sage Publications Ltd, 2013) Bay, A.; Dogan, M.; Bulan, K.; Kaba, S.; Demir, N.; Oner, A. F.
Pica is defined as developmentally inappropriate consumption of nonnutritive substances for at least 1 month. There are a few studies on serum trace element levels of patients with pica. The literature contains contracting data on the levels of oxidative stress and antioxidant levels in patients with iron-deficiency anemia (IDA). The effect of pica on oxidative stress and antioxidant capacity has not been investigated yet. The present study evaluated the effects of pica and IDA on oxidative stress and antioxidant capacity as well as on the levels of trace elements including serum zinc and selenium in 47 children with IDA plus pica, 22 children with IDA only and 21 nonanemic children as controls. The results demonstrated significantly lower levels of serum selenium and zinc in pica and IDA groups compared to the control group. Total oxidant levels were highest in the pica group and consistently, the lowest total antioxidant capacity was observed again in the pica group. Comparison of pica and IDA groups yielded significantly lower levels of total antioxidant levels and significantly higher oxidative stress index in the pica group. Consequently, it is thought that the detrimental effects of pica within the organism were mediated by adverse impacts on antioxidant capacity and oxidative stress. These effects should be kept in mind while managing patients with pica.
Supernumerary Nipples, Congenital Scoliosis, Spina Bifida Occulta, Tethered Cord and Diastematomyelia
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Dogan, M.; Kaba, S.; Bora, A.; Bulan, K.; Kocaman, S.
A 3-months old girl who presented to our clinic with accessory breast and had signs of supernumerary nipples, congenital scoliosis and diastematomyelia was presented as she didn’t correspond to any known syndrome. © 2015 Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Two Novel Associations in a Case With Walker Warburg Syndrome; Enophthalmia, Interhemispheric Cyst and Cerebral Hematoma
(Yuzuncu Yil Universitesi Tip Fakultesi, 2017) Kaba, S.; Doğan, M.; Bulut, M.D.; Bulan, K.; Demir, N.; Üstyol, L.; Ceylan, N.
There were severe brain malformations, hydrocephaly, myopathy and congenital cataract in a 5-month old girl presented with seizure. Walker Warburg syndrome is the most severe form of congenital muscular dystrophy accompanied by brain and eye anomalies. The findings in this case fulfilling diagnostic criteria of Walker Warburg syndrome other than type 2 lissencephaly suggest an intermediate form between Walker Warburg syndrome and muscle-eye-brain disease. In this manuscript, we intended to present this case presenting features (enophthalmia, interhemispheric cyst and cerebral hematoma) not reported previously in the spectrum of congenital muscular dystrophy-dystroglycanopathy with brain and eye anomalies. © 2017, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.