Browsing by Author "Bulut, M.D."

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Acute Mountain Sickness Occurring With Corpus Callosum, Globus Pallidus and Cerebellar Peduncle Involvement: Mri Findings
(2010) Avcu, S.; Arslan, H.; Göktaş, U.; Bulut, M.D.; Ünal, Ö.
Acute mountain sickness (AMS) is a pathological reaction, occurring as a result of failure to adapt to altitude. The main symptoms reported are headache, nausea, vomiting and fatigue. However, high altitude cerebral and pulmonary edema, occurring in AMS, cause potentially fatal consequences. In our 31-year-old case, who is the group leader and activity organizer among nine mountaineers, who climbed Mt. Aĝri{dotless} for winter climbing, nausea, vomiting, unconsciousness, lack of appetite and severe headache have occurred in connection with high altitude at 4200 m. Brain MRI of the patient revealed wide-spread hyperintense lesions at subcortical white matter, corpus callosum, globus pallidi, and bilateral cerebellar peduncles on T2 and FLAIR series. The patient was referred to anesthesia-intensive care unit of our hospital. Since the appearances are demonstrative, MRI findings are presented. © 2010 Elsevier Ireland Ltd.
Computed Tomography: Are We Aware of Radiation Risks in Computed Tomography
(Yuzuncu Yil Universitesi Tip Fakultesi, 2014) Bora, A.; Açıkgöz, G.; Yavuz, A.; Bulut, M.D.
People are constantly exposed to varying radiation and almost all of this exposure is due to diagnostic procedures. Although radiation has been proven to have adverse biological effects on living organisms, radiological examinations have an indispensable role in the diagnosis. Particularly, Computed Tomography (CT) is valuable imaging tool and plays an important role in the evaluation of many diseases. Radiation doses from CT scans ought to be kept to the ALARA (as low as reasonably achievable) and it shouldn’t be forget that procedures are important in patient safety during imaging in the diagnostic radiology departments. The purpose of this review article is to support that no radiation doses can be considered completely safe and all efforts must be made to reduce both the radiation dose and damage. © 2014, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Dyke-Davidoff Syndrome With Cerebral Hypometabolism and Unique Crossed Cerebellar Diaschisis in 18f-Fdg Pet/Ct
(2015) Demir, Y.; Sürücü, E.; Çilingir, V.; Bulut, M.D.; Tombul, T.
A 23-year-old man with Dyke-Davidoff-Masson syndrome (DDMS) was admitted to the hospital with increasing frequency of epileptic seizures. Physical examination revealed mental retardation, left facial asymmetry, and left-sided spastic hemiparesis. Dysdiadochokinesia on the left upper limb was detected, and there was no dysmetria. MRI confirmed the well-known radiological features of DDMS. PET/CT demonstrated cerebral and contralateral cerebellar hypometabolism. We present DDMS with crossed cerebellar diaschisis, which was demonstrated by PET/CT.
Giant Aneurysmal Bone Cyst of the Rib
(TIP ARASTIRMALARI DERNEGI, 2012) Avcu, S.; Toprak, N.; Bulut, M.D.; Ünal, O.
Aneurysmal bone cyst (ABC), especially in the ribs, is a rare disease, considering to be a benign lesion which occurs mostly in children and young adults. This case, however, concerns a 46-year-old female patient, with complaints of pain and palpable mass in the right thoracic wall, who was diagnosed to have ABC originating from the rib demonstrated by radiological examinations, aspiration biopsy, and histopathological verification. Surgical resection was performed to the lesion.
Is Immunohistochemical Sex Hormone Binding Globulin Expression Important in the Differential Diagnosis of Adenocarcinomas
(Asian Pacific Organization for Cancer Prevention, 2016) Bulut, G.; Kosem, M.; Bulut, M.D.; Erten, R.; Bayram, I.
Adenocarcinomas (AC) are the most frequently encountered carcinomas. It may be quite challenging to detect the primary origin when those carcinomas metastasize and the first finding is a metastatic tumor. This study evaluated the role of sex hormone binding globulin (SHBG) positivity in tumor cells in the subclassification and detection of the original organ of adenocarcinomas. Between 1994 and 2008, 64 sections of normal tissue belonging to ten organs, and 116 cases diagnosed as adenoid cystic carcinoma and mucoepidermoid carcinoma of the salivary gland, lung adenocarcinoma, invasive ductal carcinoma of the breast, adenocarcinoma of stomach, colon, gallbladder, pancreas and prostate, endometrial adenocarcinoma and serous adenocarcinoma and mucinous adenocarcinoma of the ovary, were sent to the laboratory at the Department of Pathology at the Yuzuncu Yil University School of Medicine, where they were stained immunohistochemically, using antibodies against SHBG. The SHBG immunoreactivity in both the tumor cells and normal cells, together with the type, diffuseness and intensity of the staining were then evaluated. In the differential diagnosis of the adenocarcinomas of the organs, including the glandular structures, impressively valuable results are encountered in the tumor cells, whether the SHBG immunopositivity is evaluated alone or together with other IHC markers. Further extensive research with a larger number of cases, including instances of cholangiocarcinoma and cervix uteri AC [which we could not include in the study for technical reasons] should be performed, in order to appropriately evaluate the role of SHBG in the differential diagnosis of AC.
Magnetic Resonance Imaging Findings in Cerebral Venous Thrombosis Due To Behcet's Disease and the Importance of Susceptibility-Weighted Imaging: Case Report
(Turkish Society of Cerebrovascular Diseases, 2015) Bulut, M.D.; Yavuz, A.; Milanlioglu, A.; Bora, A.; Gülsen, I.
Cerebral venous thrombosis (CVT) is an uncommon disorder that can lead to an unfavorable prognosis and even be fatal in some cases. CVT is seen mainly in females, especially those between the ages of 20 and 35 years. The disorder has many etiologic factors. This report presents the case of a 34-year-old male patient with Behçet's disease admitted with complaints of headache and vomiting. The major venous vascular structures that were visible in cranial magnetic resonance imaging (MRI) and MR venography were found to be filled with thrombosis. The patient's susceptibilityweighted imaging (SWI) revealed marked hypointensities consistent with thrombosis in the transverse sinus, sigmoid sinus, and in the venous vascular structures of the posterior fossa. Thus, it was found that cerebral venous thrombosis due to Behçet disease could clearly be determined by the SWI sequence; in addition, thrombosis by the venous vascularity in veins of the posterior fossa were more visible than via the other MR sequences. The conclusion was made that SWI can promptly demonstrate cerebral venous thrombosis, contribute to the diagnosis, and provide useful additional information.
Mixed Type Adrenal Cyst: a Case Report
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Bulut, G.; Bulut, M.D.; Yilmaz, D.; Celik, S.; Toprak, N.
Adrenal cysts are rare lesions that usually progress asymptomatically. They are often determined postmortem. Our case was a 50-year old-male who had presented to our clinic with upper right quadrant pain. The computed tomography demonstrated a cystic mass in the adrenal gland. No abnormalities were determined in the laboratory tests. According to the histopathological and immunohistochemical examination, the cyst was evaluated as a mixed-type adrenal cyst, the wall of which was covered with endothelium, mesothelium and cubic epithelium. We believed that the case was worth presenting, since it was the first diagnosed mixed-type adrenal cyst in the literature. © 2015, Yuzuncu Yil Universitesi Tip Fakultesi, Universitas Indonesia. All rights reserved.
Psychotic Attacks Due To Toxic Neurobrucellosis in Two Adolescent Patients
(Yerkure Tanitim ve Yayincilik, 2014) Ozdemir, O.; Baran, A.I.; Cilingir, V.; Bulut, M.D.; Ozdemir, P.G.; Yilmaz, E.
Brucellosis is a multisystem disease which can present with a broad spectrum of clinical manifestations and complications and affect the central nervous system directly or indirectly. Immunopathologic mechanisms like T-cell mediated cytotoxicity and microglia activation are suggested to play a role in neurobrucellosis. The diagnosis of toxic neurobrucellosis is confirmed by isolation of Brucella organism from blood cultures and/or positive Coombs Wright test and the Standard agglutination test (SAT) in serum when there are no cerebrospinal fluid (CSF) findings. The magnetic resonance imaging (MRI) of brain in patients with neurobrusellosis may show different findings mimicking such neurological diseases as inflammation, white matter changes and vascular involvements and other infectious and inflammatory conditions. Different clinical manifestations of neurobrucellosis have been described including meningitis, meningoencephalitis, myelitis, and psychiatric disorders. It has been indicated in case studies that neurobrucellosis may lead to psychotic disorders. In this study, we present two adolescents who presented with psychotic symptoms due to toxic neurobrucellosis.
Sleep Apnea and Fatty Liver Are Coupled Via Energy Metabolism
(International Scientific Literature Inc., 2016) Arısoy, A.; Sertoğullarından, B.; Ekin, S.; Özgökçe, M.; Bulut, M.D.; Huyut, M.T.; Turan, M.
Background: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder characterized by intermittent hypoxia. Non-alcoholic fatty liver disease is the most common cause of chronic liver disease worldwide. We aimed to evaluate the relationship between OSA and fatty liver. Material/Methods: We enrolled 176 subjects to this study who underwent polysomnography (PSG) for suspected OSA. The control group included 42 simple snoring subjects. PSG, biochemical tests, and ultrasonographic examination were performed all subjects. Results: The simple snoring and mild, moderate, and severe OSA groups included 18/42 (42.86%), 33/52 (63.5%), 27/34 (79.4%), and 28/48 (79.2%) subjects with hepatosteatosis, respectively. There were significant differences in hepatosteatosis and hepatosteatosis grade between the simple snoring and the moderate and severe OSA groups. Logistic regression analysis showed that BMI and average desaturation were independently and significantly related to hepatic steatosis. Conclusions: Our study shows that BMI and the average desaturation contribute to non-alcoholic fatty liver in subjects with OSA. In this regard, sleep apnea may trigger metabolic mitochondrial energy associated processes thereby altering lipid metabolism and obesity as well. © Med Sci Monit, 2016.
T-Cell Lymphoblastic Leukemia as a Rare Cause of Bilateral Nephromegaly
(2012) Akbayram, S.; Akgun, C.; Peker, E.; Bulut, M.D.; Aktar, F.; Oner, A.F.
Two Novel Associations in a Case With Walker Warburg Syndrome; Enophthalmia, Interhemispheric Cyst and Cerebral Hematoma
(Yuzuncu Yil Universitesi Tip Fakultesi, 2017) Kaba, S.; Doğan, M.; Bulut, M.D.; Bulan, K.; Demir, N.; Üstyol, L.; Ceylan, N.
There were severe brain malformations, hydrocephaly, myopathy and congenital cataract in a 5-month old girl presented with seizure. Walker Warburg syndrome is the most severe form of congenital muscular dystrophy accompanied by brain and eye anomalies. The findings in this case fulfilling diagnostic criteria of Walker Warburg syndrome other than type 2 lissencephaly suggest an intermediate form between Walker Warburg syndrome and muscle-eye-brain disease. In this manuscript, we intended to present this case presenting features (enophthalmia, interhemispheric cyst and cerebral hematoma) not reported previously in the spectrum of congenital muscular dystrophy-dystroglycanopathy with brain and eye anomalies. © 2017, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Ultrasound-Guided Percutaneous Treatment of Abscess Foci in Different Localizations of the Body: Results of Three Year-Experience
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Bulut, M.D.; Yavuz, A.; Bora, A.; Batur, A.; Beyazal, M.; Avcu, S.
In this study, we evaluated abscess foci which are found in different localizations of the body, diagnosed with US, CT and MRI and performed US-guided percutaneus drainage. We evaluated the effectiveness of treatment, etiologic factors, organs and localizations of abscess in the cases who underwent drainage. A total of 63 patients diagnosed with abscess in different tissues and organs, had US-guided percutaneous drainage performed (34 male, 29 female aged between 1-75 years), and 68 abscess foci were analysed. Abscess size varied between 2.5-21 cm and the mean diameter was detected as 8 cm. Diagnosis of abscess was made with US in 45 cases, CT in 23 cases and MRI in 6 cases. While 48 out of 68 abscess foci were simple, 20 were multilocular and contained septations. Air was observed in 19 of all abscess foci. Clinical findings of abscess completely resolved in 60 out of 63 patients who underwent abscess drainage (95.2%). In 3 abscess, the abscess cavity did not shrink as desired due to multiloculation, dense content, adhesions and fistulization. A drainage catheter had also been inserted, so a decision of surgical therapy was made. Secondary drainage was applied due to recurrence in 2 patients. Thirty two abscess foci (47%) developed postoperatively. Complications were not observed in any of the cases. The duration of catheter was calculated as 5-23 days (mean 10.5 days). US-guided percutaneous drainage should be the primarily preferred method in treatment of abscess and collections as it is easily applicable, does not require general anesthesia, is well tolerated, and has high success and low complication rates. © 2015, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.