Browsing by Author "Bulut, Mustafa Orhan"

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Characteristics and Transcatheter Closure of Patent Ductus Arteriosus in Patients Living at Moderate To High Altitude in Eastern Anatolia
(Turkish Soc Cardiology, 2019) Epcacan, Serdar; Bulut, Mustafa Orhan; Kaya, Yuksel; Yucel, Ilker Kemal; Cakir, Cayan; Sisli, Emrah; Celebi, Ahmet
Objective: The incidence of patent ductus arteriosus (PDA) is greater among patients living at high altitude. In this population, the ductal diameter is often larger and pulmonary hypertension is more frequent. The aim of this study was to evaluate the hemodynamic and morphological features of PDA and transcatheter closure procedures performed with various devices in a group of patients living at high altitude in Turkey. Methods: The data of 327 patients who lived at an altitude of at least 1600 m above sea level and who had undergone cardiac catheterization for isolated PDA between May 2010 and July 2018 were retrospectively analyzed. Results: The mean age was 7.33 +/- 7.67 years, and 62.4% of the patients were female. The mean ductal diameter was 3.74 +/- 2.14 mm. Pulmonary hypertension was present in 57.8%. Transcatheter closure was performed in 322 patients, with a 97.3% success rate. The Amplatzer duct occluder I (ADO I) was used most often, as well as off-label use of the Amplatzer vascular plug II (AVP) and the Amplatzer muscular ventricular septal defect occluder (AMVSDO). Pulmonary artery pressure decreased immediately in the vast majority after percutaneous closure. Transient left ventricular systolic dysfunction after ductal closure was seen only rarely. Follow-up was uneventful. Conclusion: Transcatheter PDA closure can be performed with high success rate in highlanders. Off-label devices may be required for these procedures. Pulmonary hypertension is frequent but regresses after ductal closure. Transient left ventricular dysfunction after transcatheter closure is rarely seen in these patients and resolves without any medication.
Percutaneous Closure of Secundum Atrial Septal Defects in Pediatric and Adult Patients: Short-, and Mid-Term Follow-Up Results
(Kare Publ, 2013) Kaya, Yuksel; Yurtdas, Mustafa; Ceylan, Yemlihan; Bulut, Mustafa Orhan; Soylemez, Nihat; Guvenc, Tolga Sinan; Ozkan, Mehmet
Objectives: We aimed to evaluate the shortand mid-term results of patients with atrial septal defect (ASD) who were treated with percutaneous closure. Study design: Seventy-nine patients with a diagnosis of secundum ASD (54 female and 25 male; mean age 26.2+/-17.2; range 3 to 71] years) were included in this study. All patients were evaluated by transthoracic (TTE) and/or transesophageal echocardiography (TEE). Amplatzer septal occluder (ASO) was used for percutaneous closure in all patients. In 76 patients, the procedure was performed under local anesthesia with TTE, while in the other 3 patients, it was performed with general anesthesia under the guidance of TEE. Patients were followed up at the 1st, 3rd, 6th and 12th months and annually thereafter. Mean followup period was 13.6+/-6.6 months. Results: Mean diameter of ASDs was 18.2+/-7.5 mm and stretched diameter was 20.7+/-8.04 mm during balloon dilatation, and mean diameter of implanted devices was 22.7+/-8.5 mm. Procedural time was 40.2+/-12.6, and fluoroscopy time was 10.9+/-4.1 minutes. The procedure was successfully performed in all patients (100%). One patient with cardiac tamponade died seven days after cardiac surgery. In two patients, the implanted devices embolized to the pulmonary circulation. Residual flow was found in three patients immediately after the procedure, without residual shunts one month after closure. Mild pericardial effusion in one patient and significant residual shunt due to device malposition in another were discovered at 1 and 6 months of the postprocedural follow- up period, respectively. Conclusion: Our findings showed that percutaneous closure of ASDs is successful in most patients with a low complication rate, and demonstrated that residual shunts do not develop in the majority of patients in the shortand mid- term.