Browsing by Author "Canbaz, Yasin"

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Bipediküllü Fibular Flep ile Tibia Rekonstrüksiyonu
(2016) Tekin, Hakan; Sultanoğlu, Yılmaz; Yüce, Serdar; Kahraman, Ahmet Nedim; Canbaz, Yasin
Tibia kemik kayıpları konjenital, enfeksiyon, tümöral oluşumlar ve travmalara bağlı olarak gelişebilir. Ekstremite kaybını önlemek için tibial kemiğin rekonstrüksiyonu şarttır. Rekonstrüksiyon için, distraksiyon osteogenezis, otojen kemik greftleri veya kemik flepleri kullanılabilir. Tibia yerine geçebilecek büyüklükte ve dayanıklılıkta otojen bir kemik bulmak oldukça zordur. Özellikle büyük tibia defektlerinde fibula kemik flebi rekonstrüksiyonda sıklıkla kullanılır. En büyük dezavantajı kalınlığının yeterli olmaması sebebi ile stres kırıklarına maruz kalabilmesidir. Burada sunulan olguda 22 yaşında sağ tibiada Gustilo tip III yaralanması olan hastanın 15 cm boyutundaki tibial kemik ve cilt-yumuşak doku defekti vardı. Aynı bacaktan hazırlanan bipediküllü fibula filebi ile onarım yapıldı. Cilt defekti örtümü için serbest anterolateral uyluk flebi (ALT) ile kapatıldı. Fibula flebi başarılı oldu. ALT flebi ise 72. saatte kullanıldı. Fibula üzeri ikinci seans uygulama ile kısmi kalınlıkta cilt grefti ile kapatıldı. Hastanın 12 aylık düzenli takibinde fibulaya kontrollü yük uygulandı. X-ray görünümünde fibula tamamen tibiaya adapte olmuş ve kalibrasyonu orijinal tibia çapının ¾ seviyesine ulaşmış olduğu görüldü. Her iki ekstremite boyu eşitti. Hasta desteksiz şekilde ayakta durabiliyor ve yürüyebiliyordu. Cerrahinin süresinin kısa olması, güvenilir ve dönor alan morbiditesinin düşük olması tekniğin avantajı iken kalibrasyon zayıflığına bağlı stres kırıklarına karşı dayanıksız olması dezavantajıdır
Comparison of the Effectiveness of Thymoquinone, St. John Wort Oil and Silver Sulfadiazine in Experimental Burn Wounds
(Oxford Univ Press, 2024) Canbaz, Yasin; Karakol, Percin; Erten, Remzi; Mercantepe, Tolga; Alp, Hamit Hakan; Canbaz, Esra Turan; Yuce, Serdar
We aimed to compare the effectiveness of thymoquinone (TQ), the most important bioactive component of black cumin, St. John wort (SJW) oil, a traditional medicinal plant used in burns, and silver sulfadiazine (AgSD), a well-known antiinflammatory agent used in modern medicine, in an experimental burn rat-model. Sixty-three Wistar-Albino rats were randomly divided into 9 groups (n = 7). TQ and SJW were administered topically and systemically but AgSD was applied topically. Epithelialization, inflammatory cell response, granulation tissue, vascularization, and fibrosis were evaluated. Malondialdehyde (MDA), total antioxidant status (TAS), total oxidant status (TOS), vitamin E, 8-hydroxy-deoxyguanosine (8-OHdG), coenzyme Q10 (CoQ10) were analyzed in serum. Topical TQ accelerated the epithelialization, enabled granulation, vascularization, and fibrosis in wounds (P = .001). Topical and systemic TQ increased Vitamin E levels (P = .003) but reduced TOS and 8-OHdG levels (P = .001). Topical SJW reduced granulation and vascularization. Topical and systemic SJW decreased TOS, MDA, and 8-OHdG levels (P = .001) but increased TAS (P = .001) and Vitamin E levels (P = .003). Topical AgSD reduced TOS, 8-OHdG, and MDA levels (P = .001). Topical and systemic TQ demonstrated significant advantages in accelerating the wound healing process while also enhancing antioxidant defenses and reducing oxidative damage. SJW oil, particularly in topical application, improved epithelialization, and antioxidant status but showed less efficacy in systemic use. AgSD, while effective in reducing oxidative stress, was less successful in promoting wound healing and appeared to delay granulation and fibrosis. Thymoquinone offers superior protective and healing benefits, SJW is effective locally but less so systemically, and AgSD should be used cautiously, potentially combined with antioxidants to mitigate its negative impact on wound healing.
Comparison of the Fistula Risk Associated With Rotation Palatoplasty and Conventional Palatoplasty for Cleft Palate Repair
(Lippincott Williams & Wilkins, 2014) Kahraman, Ahmet; Yuce, Serdar; Kocak, Omer Faruk; Canbaz, Yasin; Guner, Sukriye Ilkay; Atik, Bekir; Isik, Daghan
The aims of the cleft palate repair techniques are to reduce the velopharyngeal insufficiency risk and oronasal fistula development to minimal levels without affecting the maxillofacial development. In this article, we present a retrospective study comparing the conventional palatoplasty techniques with the new technique of rotation palatoplasty for the risk of development of oronasal fistula. Materials and Methods: Of the 100 patients who were operated on because of cleft palate between the years 2002 and 2008, 12 patients had Furlow palatoplasty, and 88 patients received the Veau-Wardill-Kilner (V-Y pushback) operation (group C). A total of 67 patients who were operated on between 2008 and 2011 had rotation palatoplasty (group R). Results: One hundred patients were men, and 67 were women. Among all the patient groups, 22.8% were classified as Veau 1, 24.6% were classified as Veau 2, 37.1% were classified as Veau 3, and 15.6% were classified as Veau 4. The rate of fistula was found to be 17.7% in all patients. Fistula development was found in 6% of the patients in group R (4/67) and in 18% of the patients in group C (18/100). The difference between group R and group C regarding the number of patients who developed fistula was statistically significant (P = 0.011). Conclusions: The Veau classification of the cleft palate affects the risk of fistula development, and the risk for fistula after rotation palatoplasty is lower than that associated with the V-Y pushback technique.
Congenital Lateral Cleft Palate of Unknown Etiology
(Lippincott Williams & Wilkins, 2015) Kahraman, Ahmet; Yuce, Serdar; Kocak, Omer Faruk; Canbaz, Yasin; Isik, Daghan
The term cleft palate (CP) refers to midline defects extending from the prealveolar ark to the uvula, and these defects present with varying degrees. CP may be complete, incomplete, unilateral, bilateral, or submucosal. It is often observed with cleft lip (CL). In various studies, the incidence of isolated CP has been reported as 1.3 to 25.3 per 1000 births. 1,2 As a result of deterioration of the anatomical structure of the palate, illnesses such as regurgitation, respiratory tract infections, otitis, and speech disorders may occur. These defects are often observed in the midline and are rarely laterally localized. Cleft palates with lateral localization are outside the natural midline cleft closure line and cause clinical complaints similar to other types of CP. Two cases of laterally localized CP have previously been published in the literature. 3,4 The case presented here is the third known case to be reported.
Effects of Ozone Pretreatment on Viability of Random Pattern Skin Flaps in Rats
(Taylor & Francis Ltd, 2015) Oksuz, Mustafa; Yuce, Serdar; Kocak, Omer Faruk; Canbaz, Yasin; Ragbetli, Murat Cetin; Mercantepe, Tolga
Background: Medical ozone is a chemical agent that consists of three oxygen atoms and has antioxidant, angiogenic and vasodilator effects. This study evaluated the effects of medical ozone pre-treatment on flap survival. Materials and methods: Rats were divided into four groups of 10 rats each and a 9 x 3 cm McFarlane flap was used. Sham group: Neither surgical nor ozone pretreatment was used. Control group: No pretreatment was used after surgery. Preoperative ozone group: Preoperative 1 mg/kg ozone was given intraperitoneally for 7 days. No pretreatment was used after surgery. Postoperative ozone Group: Postoperative 1 mg/kg ozone was given intraperitoneally for 7 days. After postoperative 1 week, all groups were evaluated by surface area measurement, histopathology and electron microscopy. Results: With the experimental McFarlane flap model, the experimental groups had better surface area measurements, along with histopathological and electron microscopic results when compared with the control group. Conclusion: Medical ozone had positive effects on flap survival due to its antioxidant, angiogenic and vasodilator qualities.
The Effects on Complications and Myopathy of Different Voltages in Electrical Injuries
(Turkish Assoc Trauma Emergency Surgery, 2011) Karadas, Sevdegul; Gonullu, Hayriye; Oncu, Mehmet Resit; Isik, Daghan; Canbaz, Yasin
BACKGROUND The purpose of this study was to investigate the demographic and clinical characteristics of electrical injuries, laboratory findings, complications, and mortality and morbidity rates of these injuries. METHODS Patients with electrical injuries admitted to the emergency department between January 2006-2010 were retrospectively analyzed. The cases were evaluated by age, gender, source of electrical power (low-high voltage), seasonal distribution, ECG changes, laboratory findings, clinical care units, complications, and mortality rate. RESULTS Eighty-four (57.1%) of the cases were exposed to low-voltage electricity (Group I), while 63 (42.9%) of the cases were exposed to high-voltage electricity (Group II). The majority of cases with electrical injuries were aged 26-45 years. Thirty of the women (85.7%) were wounded by low-voltage while 58 of the men (51.8%) were wounded by high-voltage electricity. Alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, creatine kinase, and CK-MB levels were higher and the level of calcium was lower in Group II. Complications (pathologies due to fall from high levels, cardiac dysrhythmias, compartment syndrome) and the mortality rate were higher in Group II. CONCLUSION In cases with high-voltage electrical injuries, cardiac complications, complications due to fall from high levels and the mortality rate increase in conjunction with the degree of the muscle damage.
Evaluation of Effect of Thymoquinone, St. John Wort, and Silver Sulfadiazine on Experimental Burn Wound
(2014) Canbaz, Yasin; Yüce, Serdar
Amaç: Yara iyileşmesi, insanlığın var olmasından beri göz önünde olup en bilinen fizyolojik olaylardan biri olmasına karşın halen tam olarak anlaşılamamış, karmaşık, multisistemik bir süreçtir. Tam anlaşılamamış olması, birçok yeniliğe ve araştırmaya açık olması sonucunu ortaya çıkarmıştır. Bu çalışmada, antioksidan, antiinflamatuar, antitümöral, antihistaminik ve antibakteriyel özellikleri olan Timokinon, dünyanın birçok tarafında yüzyıllardır yanık ve yara tedavisinde kullanılan Kantaron yağı ve yaygın kullanım alanı olan Gümüş Sülfadiazin'in yanık yarası üzerine etkilerinin karşılaştırılması planlandı. Materyal ve Metod: Çalışmada ağırlıkları 200-250 gram arası olan 63 adet Wistar-Albino cinsi sıçan kullanıldı. Her grupta 7 sıçan olacak şekilde 9 gruba ayrıldı. 1. Grup (sham) her hangi bir işlem uygulanmadı, 2. Grup (kontrol) yanık yarası oluşturuldu, tedavi verilmedi, 3. Grup (topikal timokinon) topikal 2 mg/kg Timokinon uygulandı, 4. Grup (topikal Kantaron yağı) topikal 0.75 cc Kantaron Yağı uygulandı, 5. Grup (gümüş sülfadiazin) topikal gümüş sülfadiazin uygulandı, 6. Grup (sistemik Timokinon) intraperitoneal 2 mg/kg Timokinon uygulandı, 7. Grup (sistemik Kantaron yağı) intraperitoneal 0.75 cc Kantaron Yağı uygulandı, 8. Grup (topikal+sistemik Timokinon) topikal 2 mg/kg ve intraperitoneal 2 mg/kg Timokinon uygulandı, 9. Grup (topikal+sistemik Kantaron Yağı) topikal 0.75 cc ve intraperitoneal 0.75 cc Kantaron Yağı uygulandı. Çalışma sonunda kan ve doku örnekleri alınıp histopatolojik, biyokimyasal ve elektron mikroskobik değerlendirme yapıldı. Bulgular: Histopatolojik olarak Timokinon grupları daha fazla epitelize oldu ve granulasyon dokusu daha fazla gelişti. Biyokimyasal olarak, TOS düzeyi azalmış, Vitamin E artmış, 8OHdG ve MDA azalmış olarak saptandı. Elektron mikroskopisinde Timokinon gruplarında mitokondri bütünlükleri korunmuş olarak gözlendi. Kantaron yağı gruplarında epitelizasyonun arttığı, inflamasyonun azaldığı, granulasyonun ve vaskülarizasyonun geri kaldığı, TAS ve vitamin E düzeyinin arttığı, TOS, MDA ve 8OHdG'nın azaldığı ve elektron mikroskopisi olarak mitokondri yapısının kontrol grubundan iyi olmakla beraber Timokinon gruplarından biraz kötü olduğu gözlendi. Gümüş sülfadiazinde ise epitelizasyon ve antienflamatuar etki kontrolden daha iyi saptandı. Granulasyon dokusu gelişimi, neovaskülarizasyon ve fibrozis açısından ise daha kötü olduğu gözlendi. TOS, MDA, 8-OHdG düzeylerini azalttığı, TAS, Vitamin E ve KoenzimQ10 düzeylerini artıramadığı gözlendi. Elektron mikroskopisinde mitokondriyal yapıların korunduğu gözlendi. Sonuç: Timokinon' nun yara iyileşmesini artırıcı ve koruyucu antioksidan etkileri mevcuttur. Kantaron yağı Timokinon' un bir miktar gerisinde kalmakla birlikte, yara iyileşmesini artırıcı ve koruyucu antioksidan etkilere sahiptir. Gümüş sülfadiazin ise yara iyileşmesini geciktirmekle birlikte oksidan ajanları nötralize etmektedir. Anahtar Kelimeler: Timokinon (Thymoquinone/ TQ), Kantaron yağı, gümüş sülfadiazin, deneysel yanık yarası.
The Forehead Flap With Subdermal Pedicle
(Medknow Publications & Media Pvt Ltd, 2012) Isik, Daghan; Sarici, Murat; Garca, M. Fatih; Canbaz, Yasin; Atik, Bekir
Objective: Although the forehead flap is an axial flap, in contrary to the other axial flaps, its use as an island flap is not popular. The aim of this study is to present the patients in whom the forehead flaps with subdermal pedicle were used. Methods: The forehead flap with subdermal pedicle was used for 7 patients aged between 45 and 65 years. All patients were operated with the diagnosis of skin cancer. Four and two of the lesions were in the nasal and medial canthal regions, respectively. The lesion was involved nasal dorsum and medial chantal region together in one patient. The forehead flap was used with subdermal pedicle in all patients. The second session in which the flap was divided was performed 3 weeks after the first session. Results: Flap loss was not observed in any patients and basal cell skin cancer was diagnosed in the histopathological examination of all lesions. In five patients, within 3 months, reduced or completely dissolved depression was noted in the donor area of the flaps. Conclusion: The use of forehead flap as an island flap does not affect flap vascularity and provide less scar formation in the donor area.
Gestational Gigantomastia After the Breast Reduction Surgery: a Case Report
(Medknow Publications & Media Pvt Ltd, 2011) Isik, Daghan; Kurdoglu, Zehra; Canbaz, Yasin; Tekin, Hakan; Atik, Bekir
Gestational gigantomastia is a rare and complex disorder characterized by massive enlargement of breasts during pregnancy and resulting in tissue necrosis, ulceration, infection. In most cases, gigantomastia is caused by an excess of circulating hormones or by the hypersensitivity of mammary tissue to normal hormone stimulation. Medical therapies to treat gestational gigantomastia are unpredictable in outcome. Breast reduction or mastectomy with delayed reconstruction is the preferred surgical procedure. If the mother is considering future pregnancies, mastectomy offers the lowest risk of recurrence. The present case with gestational gigantomastia is a patient who was underwent breast reduction using with free nipple reduction technique after the previous pregnancy.
Kutlay Technique for Hypospadias Repair
(Springer, 2012) Gecit, Ilhan; Isik, Daghan; Pirincci, Necip; Bilici, Salim; Gunes, Mustafa; Canbaz, Yasin; Kocak, O. Faruk
Although many techniques have been described, new techniques with a wide range of therapeutic options are needed. The Kutlay technique is a novel technique that is based on the reconstruction of the neourethra with two horizontal meatal-based skin flaps. In the present study, the data of 31 patients who underwent surgery with the Kutlay technique are presented. Thirty-one patients with hypospadias with an average age of 5.6 years who did not have previous hypospadias repair were operated on with the Kutlay technique. Ten patients had chordee. Among those patients, three patients were circumcised. The patients were followed up for 4-13 months (average, 9.3 months). During the follow-up period, a fistula was observed in only one patient. None of the patients developed neourethral dehiscence, meatal stenosis, urethral stricture, wound infection, penile torsion, hematoma, or persistent or recurrent chordee. On uroflowmetry studies, the maximum flow rate of the patients was approximately 10.5 ml/s (range, 6-17 ml/s). The patients were observed to void with a single straight urinary stream in a forward direction. The Kutlay technique is a technique that is easily applied in patients with chordee and that provides a low risk of fistulas and acceptable functional and esthetic results. The factors that reduce the risk of fistula are the lack of the superposition of the suture lines of the skin and the urethra, the reconstruction of the urethra with well-vascularized flaps, and the replacement of the neourethra in its appropriate location through the tunnel created in the glans.
Pregnancy and Trauma: Analysis of 139 Cases
(Galenos Yayincilik, 2012) Karadas, Sevdegul; Gonullu, Hayriye; Oncu, Mehmet Resit; Kurdoglu, Zehra; Canbaz, Yasin
Objective: The aim of this study was to examine the diagnoses and treatment methods and demographical and clinical characteristics of pregnant women who were exposed to trauma and in additon, review of the literature was carried out in this regard. Material and Methods: One hundred thirty-nine pregnant women who presented at the Yuzuncu Yil University between January 2006 and September 2009 with local or general body trauma complaints were analysed retrospectively. Results: The average age of the cases was 26.72 +/- 6.29 years and the age group ranging from 21-34 composed the majority. When they were studied according to their etiologies, falls during daily activities formed 43.9%. When they were analyzed in terms of their gestational weeks, 64.46% were in the 3rd trimester. Pregnant cases with trauma resulted in maternal (3 cases) and fetal (9 cases) loss. It was found that 19 cases who had imaging techniques involving radiation and whose gestation was continuing had a problem-free gestation period and healthy children. Conclusion: It is mandatory to evaluate both mother and fetus together when trauma exposure is in question, the general well-being of the fetus should be provided and the mother should be informed about the presence of advanced trauma life support.
Reconstruction of the Tibia With a Bipedicle Fibular Flap
(Medknow Publications & Media Pvt Ltd, 2016) Kahraman, Ahmet; Yuce, Serdar; Tekin, Hakan; Canbaz, Yasin; Sultanoglu, Yilmaz
Tibial defects can be caused by trauma, congenital, osteomyelitis, or cancers. The tibia is the main bone for bearing the body. It is a big bone, and the difficulty of the reconstruction of tibia is importance to repair it. The fibular bone is a good provider for repairing the tibia defects. Generally, the repair was planned be a free vascularized flap. The most important disadvantage is the low calibration. In early age in particular, the original thickness of the tibia is reached after the surgery with a good follow-up process and rehabilitation. In this case; a 22-year-old female patient had a multi-part post-traumatic fracture of the left tibia and was administered to our plastic surgery inpatient clinic. The bone defect was reconstructed with a bipedicle fibular flap taken from the same leg. The fibula was embedded into the medulla with a screw plate, and fixation was applied with an external fixator. Wherefore the loss of skin, skin flap of fibula bottomed of perforators was not used. A vascularized anterolateral thigh flap, which was obtained from the other leg, was used to reconstruct the skin defect. One year after surgery, the bone viability was perfect. The integrity of the skeleton was created without shortening the leg. The rehabilitation of the patient was continued for repowering and resizing the fibula up to tibia. In this case report, we wanted to share our experience for repairing the tibia defect with using a bipedicle fibular flap.
Upper Extremity Injuries Due To Threshing Machine
(Turkish Assoc Trauma Emergency Surgery, 2012) Isik, Daghan; Ceylan, M. Fethi; Tekin, Hakan; Karadas, Sevdegul; Guner, Savas; Canbaz, Yasin
BACKGROUND The aim of this study was to report the patients who were admitted to our hospital with upper extremity injuries due to threshing machine, to determine the most appropriate classification, to estimate the treatment modalities, and to discuss the prevention methods. METHODS Twenty-five patients who had suffered injuries sustained by a threshing machine were retrospectively investigated. The patients were analyzed with respect to age, gender, admission month, hospitalization period, the type of injured tissue, and the treatment modality. RESULTS Twenty-four of the patients were male and one was female, and the mean age of the patients was 19.4 (2-51) years; 60% of the patients were under the age of 15. The patients were admitted most commonly in the month of August. CONCLUSION We believe that shielding the rotating components of farming machinery that cause injuries, informing and educating farming families (by physicians), forbidding the entrance of children to areas with agricultural machines, providing information to children in schools (in those regions with developing agriculture) about agricultural accidents and,. their prevention methods, and adjusting the working hours of farming personnel, especially in the hottest Months of the year, may be beneficial in preventing accidents due to farming machinery.
Use of Dorsal Intercostal Artery Perforator Flap in the Repair of Back Defects
(Taylor & Francis Ltd, 2016) Durgun, Mustafa; Bas, Soysal; Aslan, Cem; Canbaz, Yasin; Isik, Daghan
Background: The dorsal intercostal artery perforator (DICAP) flap is a well-vascularised flap that is elevated above the dorsal branch of the vertebral segments of the posterior intercostal artery. The aim of this study was to repair back defects using DICAP flaps. Materials and methods: Eight patients who had undergone reconstruction with DICAP flaps for defects located on the back of the torso due to conditions of various aetiologies between 2011-2014 were included in this study. Patient age and gender, aetiology of the condition, dimensions of the defect and the flap, site of the defect, and postoperative complications were recorded. Results: Three females and five males were included in this study. The age of the patients ranged between 19-71 years (mean = 53.6 years). The aetiology was skin tumour in five patients and pressure wound, gunshot injury, and plate screw exposition subsequent to spinal surgery in one patient each. The sites of the defects were successfully closed in all patients, and no flap loss was observed in any patient. Conclusions: DICAP flaps have some advantages compared to conventional muscle and muscle skin flaps, such as greater protection of muscle functions, less invasiveness, and lower donor site morbidity. This flap has a high mobilisation capacity due to its elevation above nine bilateral perforator arteries. Therefore, the DICAP flap is useful for the repair of median and paramedian back defects. Based on its advantages, it is suggested that the DICAP flap should be considered as a useful option for the repair of back defects.