Browsing by Author "Celebi, Sezgin"

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Changes in Serum Igf-1 and Igfbp-3 Levels and Growth in Children Following Adenoidectomy, Tonsillectomy or Adenotonsillectomy
(Elsevier Ireland Ltd, 2010) Kiris, Muzaffer; Muderris, Togay; Celebi, Sezgin; Cankaya, Hakan; Bercin, Sami
Objective: The aim of this study is to determine the effect of adenoidectomy, tonsillectomy or adenotonsillectomy on growth. For this purpose, we prospectively reviewed the postoperative changes in serum levels of insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3), weight and height in children that underwent adenoidectomy, tonsillectomy or adenotonsillectomy. Methods: Ninety-six children with symptoms of sleep disordered breathing (SDB) or recurrent adenotonsillitis were enrolled to study. Blood samples were taken preoperatively and repeated at 6 months following operation to determine the changes in serum IGF-1 and IGFBP-3 levels, pre- and postoperative values of weight and height were recorded for each operation. Results: Thirty-six patients underwent adenoidectomy, 52 patients underwent adenotonsillectomy and 8 patients underwent tonsillectomy. Seventy of the operations were performed for SDB and 26 were performed for recurrent adenotonsillitis. The mean serum levels of IGF-1 increased by 26%, from 126.74 +/- 112.13 ng/ml to 159.82 +/- 122.91 ng/ml (p < 0.001) and IGFBP-3 levels increased by 7%, from 3.34 +/- 1.17 mu g/l to 3.57 +/- 1.16 mu g/l (p < 0.05) 6 months after operation. The increase was independent from the preoperative diagnosis. There was a significant increase both in patients with SDB and in children with recurrent infections (p < 0.001 for IGF-1, p < 0.05 for IGFBP-3). Their Z scores (standard deviation scores) for body weights (mean Z score from -0.06 +/- 0.98 to 0.118 +/- 1.18, p < 0.001) and heights (mean Z score from 0.30 +/- 0.98 to 0.42 +/- 0.88, p < 0.001) were significantly higher 6 months after the operation compared to preoperative period. Conclusions: We found a significant increase in weight, height, and IGF-1 and IGFBP-3 levels of children with SDB or recurrent infections postoperatively. These results suggest that upper airway obstruction may not be the only mechanism that causes retardation on growth in children. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
Treatment Modalities in Maxillofacial Fractures: Retrospective Analysis
(Ortadogu Ad Pres & Publ Co, 2009) Kiris, Muzaffer; Yuca, Koeksal; Celebi, Sezgin; Kiroglu, Faruk; Cankaya, Hakan
Objective: Our aim was to analyze patients treated for maxillofacial fractures due to trauma retrospectively and to discuss the results. Material and Methods: The study comprised 138 patients [aged between 2-76 years, (mean age 29.12 +/- 14.79) 102 men, 36 women] who had attended the Department of Otorhinolaryngology, Yuzuncu Yil University Medical Faculty during February 1995-October 2006, with maxillofacial fractures due to trauma. The patients were evaluated retrospectively for etiology, localization, treatment modalities and complications, and results were compared with other studies. Results: Traffic accidents were the most common cause of maxillofacial fractures (34%), followed by falls from high (21%). Distribution of maxillofacial fractures due to trauma were as follows; mandibular fractures in 64.6% and maxillary fractures in 20.2%. Among mandibular fractures, parasymphyseal fractures were the most common by 31.5% and coronoid fractures were the least common with 0.6%. The techniques used for treatment were miniplaque application, arch-bar Gillie's method and condilectomy; miniplaque technique being the most frequently used (67.7%). The most common complication was infection. Seven patients required tracheotomy in the emergency room for respiratory distress was. Conclusion: In this study, techniques and equipments used in the treatment process changed parallel to technological developments. While wire fixation and arch-bar procedures were more frequent in the earlier cases, titanium mini-plaques and microplaques had results that were more favorable with better outcomes and less complications.