Browsing by Author "Celik, Murat"

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Inadvertent Removal of Fully Deployed Stent During Retrieval of Another Dislodged Stent
(Elsevier Ireland Ltd, 2012) Iyisoy, Atila; Celik, Murat; Celik, Turgay; Yuksel, Uygar Cagdas
The Relationship Between L-arginine/Adma Ratio and Coronary Collateral Development in Patients With Low Glomerular Filtration Rate
(Via Medica, 2012) Celik, Murat; Iyisoy, Atila; Celik, Turgay; Yilmaz, Mahmut Ilker; Yuksel, Uygar Cagdas; Yaman, Halil
Background: It is yet to be established which factors are responsible for differences among patients with the same degree of coronary artery disease in terms of coronary collateral development (CCD). Methods: Patients who had a greater than or equal to 95% stenosis in at least one epicardial coronary artery were classified into two groups according to their glomerular filtration rate (GFR) level. Afterwards, the degree of CCD was evaluated according to their plasma concentration of asymmetric dimethylarginine (ADMA) and GFR levels. Results: Rentrop grade 2-3 was found more frequently in patients with GFR > 60 mL/min than in patients with GFR < 60 mL/min (68.6% vs 41.4%, p = 0.032). Then we divided patients into four groups according to their GFR levels and Rentrop grades; whereas we did not find any significant difference for L-arginine or ADMA levels (respectively p = 0.629 and p = 0.076), we did find a statistically significant difference between groups for L-arginine/ADMA ratio (p = 0.003) and this statistically significant difference was evident between patients with GFR < 60 mL/min and Rentrop 0-1 and patients with GFR > 60 mL/min and Rentrop 2-3 (1.23 vs 1.69, p < 0.001). Multivariate logistic regression analysis revealed that L-arginine/ADMA ratio was the only variable which had a significant effect on CCD (OR = 95% CI 1.001-1.031, Wald = 4.565; p = 0.033). Conclusions: These results showed that CCD was Poor in patients with GFR < 60 mL/min, presumably because of the adverse effect of decreased L-arginine/ADMA ratio on endothelial cells and angiogenesis. (Cardiol J 2012; 19, 1: 29-35)
The Role of Intravascular Ultrasound Guidance in the Treatment of Intramural Hematoma Probably Caused by Spontaneous Coronary Artery Dissection in a Young Woman With Acute Anterior Myocardial Infarction
(Via Medica, 2012) Iyisoy, Atila; Celik, Murat; Celik, Turgay; Yuksel, Uygar Cagdas
Spontaneous coronary artery dissection (SCAD) is known to be a rare but fatal cause of acute coronary syndromes. It is more frequent in young women, particularly in the peripartum period. Intravascular ultrasound (NUS) has an important role in the diagnosis and management of SCAD. Intramural hematoma that occurs between adventitial and media layer of the vessel wall may occlude the true lumen. IVUS can identify intimal tears, the extension of intramural hematoma and show the adequate compression of intramural hematoma after percutaneous coronary intervention. We present a case of intramural hematoma caused by SCAD in a young woman presenting with acute anterior myocardial infarction, and the role of IVUS in the diagnosis and management of SCAD. (Cardiol J 2012; 19, 5: 532-535)
Scimitar Syndrome and Azygos Continuation of the Inferior Vena Cava Diagnosed in an Adult-An Unusual Association
(Wiley, 2012) Celik, Murat; Celik, Turgay; Iyisoy, Atila; Ayten, Omer
Anormal drainage of the pulmonary veins into the inferior vena cava is known as scimitar syndrome. Scimitar syndrome often presents during infancy and rarely during adulthood, and the adult patients are mostly asymptomatic. It is usually in association with dextrocardia, hypoplasia of right lung, and congenital heart defects. However, interruption of inferior vena cava with azygous continuation is rarely associated with this syndrome.
Statins and Coronary Microvascular Dysfunction in Patients With Acute St Segment Elevation Myocardial Infarction
(Elsevier Ireland Ltd, 2012) Celik, Turgay; Demirkol, Sait; Celik, Murat; Yuksel, U. Cagdas; Iyisoy, Atila
Successful Retrieval of a Broken Intravascular Ultrasound Catheter Tip From a Coronary Artery
(Elsevier inc, 2012) Iyisoy, Atila; Celik, Murat; Celik, Turgay; Yuksel, Uygar Cagdas; Samedli, Samed
The fracture of IVUS catheter tip in the coronary artery is a very rare complication. It should be removed as soon as possible. Although it seems to be easy at first glance, percutaneous retrieval of broken IVUS catheter tip has some challenges. We hereby present a case report of successful percutaneous retrieval of broken IVUS catheter, probably caused by calcific left main stenosis, from the left circumflex artery using loop snare technique. (C) 2012 Elsevier Inc. All rights reserved.
Transient Cortical Blindness Can Also Be Seen in the Absence of Contrast Enhancement at Computed Tomography Scan After Coronary Angiography
(Professional Medical Publications, 2012) Tuncer, Mustafa; Celik, Murat; Milanlioglu, Aysel; Akil, Mehmet Ata
Transient cortical blindness after coronary angiography or angioplasty is a rare complication. Patients with aortocoronary bypass grafts such as internal mammary artery have a seperate risk factor probably because of the direct contrast injection to the vertebral artery during the catheterisation of the internal mammary artery ostium. In most cases, computed tomography scan revealed typical, symmetrical contrast enhancement in both occipital lobes Nevertheless, transient cortical blindness can be seen after coronary angiography without contrast enhancement at computed tomography scan.
Vascular Inflammation and Aortic Stiffness Relate To Early Left Ventricular Diastolic Dysfunction in Prehypertension
(Taylor & Francis Ltd, 2013) Celik, Turgay; Yuksel, U. Cagdas; Fici, Francesco; Celik, Murat; Yaman, Halil; Kilic, Selim; Mancia, Giuseppe
Prehypertension is characterized by an increased cardiovascular risk and by an increased prevalence of target organ damage compared with the pure normotensive state. The present study was designed to assess in prehypertensive subjects the possible relationships between early left ventricular dysfunction, vascular inflammation and aortic stiffness. The study population consisted of 31 untreated prehypertensive subjects (age: 34 +/- 6 years, mean +/- SD) and 31 age-matched pure normotensive controls. Left ventricular function was assessed by echocardiography, aortic distensibility parameters were derived from aortic diameters measured by ultrasonography, and high-sensitivity C-reactive protein was assessed by latex-enhanced reagent. Prehypertensive subjects displayed a significantly lower E/A ratio and a significantly greater deceleration time and isovolumetric relaxation time compared with normotensive controls. They also displayed aortic systolic diameter, diastolic diameter and mean aortic stiffness index beta significantly increased while systo-diastolic diameter change, mean aortic distensibility and aortic strain were significantly reduced compared with controls. Values of inflammatory markers were increased. At multiple regression analysis, E/A ratio was significantly related to high-sensitivity C-reactive protein and aortic stiffness index beta, after correction for age, left ventricular mass index and mean blood pressure (beta coefficient = -0.49, overall r(2) = 0.24, p = 0.01 and beta coefficient = -0.46, overall r(2) = 0.21, p = 0.02, respectively). Thus, in prehypertension, left ventricular dysfunction is significantly related to vascular inflammation and aortic stiffness, suggesting that early cardiac and vascular alterations may have an increased inflammatory process as a common pathophysiological link.
Wellens' Syndrome With Segmental Wall-Motion Abnormalities
(Dove Medical Press Ltd, 2010) Celik, Turgay; Bugan, Baris; Firtina, Serdar; Celik, Murat; Demirkol, Sait; Iyisoy, Atila
Wellens' syndrome is a pattern of electrocardiographic T-wave changes associated with critical, proximal left anterior descending (LAD) artery stenosis. We herein report 2 cases of Wellens' syndrome with segmental wall-motion abnormalities The first case is a 50-year-old man admitted to the emergency department with typical chest pain. Admission ECG showed biphasic T waves in leads V-1-V-3 with inverted T waves in leads V-4-V-6, and cardiac enzymes were in normal limits. The second case is a 62-year-old woman admitted to the emergency department with chest pain on rest. Admission ECG showed deeply inverted T waves in leads V-1-V-4, and troponin T was minimally elevated. The critical lesions in the proximal segment LAD were successfully opened with stent deployments. Wall-motion abnormalities returned to normal after intervention.