Browsing by Author "Cemek, M."

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Irradiation, Radioprotection and Nigella Sativa
(Cabi Publishing-c A B int, 2008) Cemek, M.; Buyukokuroglu, M. E.; Bayiroglu, F.; Koc, M.
Major and Minor Bio-Element Status in Children With Febrile Seizure
(Comenius Univ, 2012) Akbayram, S.; Cemek, M.; Buyukben, A.; Aymelek, F.; Karaman, S.; Yilmaz, F.; Caksen, H.
Febrile seizures (FS) are the most common cause of seizures in children. The exact etiopathogenesis is unknown but involves factors like genetic predisposition and alterations in the levels of neurotransmitters and some trace elements. The study includes 48 consecutive children with FS, and 55 healthy age matched control subjects. Calcium, magnesium and potassium concentrations in the febrile study group were lower than in the control group (p<0.05). Iron and Gallium levels in the study group were lower than in the control group (p<0.01). Serum Selenium (p<0.001), Zinc (p<0.001) and Strontium (p<0.05) levels were significantly decreased in the study group when compared to the control group. There was no significant difference between the control and study groups in Serum Barium, Beryllium and Copper levels (p>0.05). The aim of the present prospective analytical case-control study was to determine whether there was any change in element levels in children with FS (Ref. 33). Full Text in PDF www.elis.sk.
Oxidant/Antioxidant System Markers and Trace Element Levels in Children With Nutritional Rickets
(2012) Doǧan, M.; Cesur, Y.; Doǧan, S.Z.; Kaba, S.; Bulan, K.; Cemek, M.
Objective: To determine the oxidative stress and trace element levels in vivo in patients with nutritional rachitism associated with vitamin D deficiency. Materials and method: A total of 30 patients, 18 males and 12 females, were included in the study. Age, sex, medical history, vital, and physical examination findings of each patient documented at presentation were recorded. Serum calcium, phosphorus, alkaline phosphatase, parathormone, and 25-OH vitamin D levels, as well as oxidant and antioxidant system parameters and trace element levels were studied. After being diagnosed with rachitism, the patients were administered a single dose of 300,000 IU vitamin D by intramuscular injection. The same analyses were repeated post-treatment. Thirty children with normal anthropometric measurements were included as the control group. The analyses described above were performed only once for the control group. Results: Serum calcium, phosphorus, alkaline phosphatase, parathormone, and 25-OH vitamin D levels were different between the controls and children in the patient group (p <0.001). Analysis of trace element levels demonstrated markedly lower pretreatment zinc levels for the patient group compared to the controls, with a statistically significant difference (p =0.001). Comparison of pretreatment oxidant and antioxidant system markers between the patient and control groups demonstrated higher values for vitamin C, β-carotene, reduced glutathione, and superoxide dismutase in the control group, whereas MDA was higher in the patient group. Conclusion: The present study demonstrated increased oxidative stress, reduced antioxidant defence system in patients with nutritional rachitism, with reduced oxidative stress and a pronounced improvement in the antioxidant system with vitamin D treatment.
Scurvy Is an Important Problem in the East of Anatolia, Turkiye: Three Cases Report
(2010) Ari Yuca, S.; Yilmaz, C.; Cemek, M.; Cesur, Y.; Çaksen, H.
Scurvy is a multisystemic nutritional disorder which synthesis of collagen is destructed due to deficiency of vitamin C and its characteristic findings on hematological system and bone. Scurvy may occur at any age, frequently in infants aged 6-24 months. It is usually affected in children with severely developmental problems and suffered from malnutrition. Causes of inadequate ascorbic acid in infancy are usually starting weaning late, giving limited fresh fruits and vegetables, and mistakes in preparing foods. There is general tenderness, frog position at legs, edematous swelling along the shafts of legs, subperiosteal hemorrhage at the knees joints in with scurvy patients. Petechial hemorrhages may occur in skin and mucous membranes. The diagnosis of scurvy is usually based on the characteristic clinical picture, the roentgenographic changes in the long bones, and history of inadequate intake of ascorbic acid in infancy. We described here, three children with suffered from scurvy who had markedly vitamin C deficient in their diets. We wish to emphasize that, it is still a problem among malnutrition children in our country. Copyright © 2010 by Türkiye Klinikleri.