Browsing by Author "Cetinkaya, Erdogan"

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Lung Cancer in Patients With Pulmonary Fibrosis: Characteristics Features and Prognosis
(Mattioli 1885, 2024) Kara, Sibel; Mo, Nesrin; Kirkil, Gamze; Cetinkaya, Erdogan; Ozbudak, Omer; Kilic, Talat; Unat, Omer Selim
Background and aim: Lung cancer is one of the significant comorbidities seen in patients with Idiopathic Pulmonary Fibrosis (IPF). However, there is limited data on non-IPF Pulmonary Fibrosis (PF) patients with lung cancer (LC). The present study aims to compare the characteristics and survival outcomes of patients diagnosed with LC in IPF and non-IPF PF. Methods: The multicenter data records of IPF and non-IPF PF patients diagnosed with lung cancer between 2010-2022 were analyzed in this descriptive, cross-sectional, and retrospective study. Results: Of the 251 patients involved in this study [164 IPF-LC, 87 non-IPF PF-LC], 89.6% were male, the mean age was 69 +/- 7.9 years and the smoking rate was 85.7%. Honeycomb pattern was more frequently observed in IPF-LC patients [62.8%,37.9%p<0.001], whereas ground-glass opacity [33.5%,59.8%p<0.001] and emphysema [37.8%,59.8%p<0.001] were more frequently seen in non-IPF PF-LC patients. The most commonly seen histological type was squamous cell carcinoma [42.7%,33.9%], followed by adenocarcinoma [28.2%; 32.2%]. [46.4%;47.2%] and their 5-year mortality rates were high [64.6%, 63.2%]. The median survival for both groups was 2 +/- 0.22 years [median 95% CI (1.55-2.44)]. The shortest survival time was observed in non-IPF PF-LC subIPF and non-IPF PF LC patients were male, elderly, and had a high smoking rate. Squamous cell carcinoma was the most frequently seen histological type and they had short survival periods and high mortality rates. The survival period of unclassified non-IPF PF-LC patients was found to be the shortest.
Research Burden of Interstitial Lung Diseases in Turkey-Rbild
(Mattioli 1885, 2022) Aycicek, Olcay; Cetinkaya, Erdogan; Ucsular, Fatma Demirci; Bayram, Nazan; Senyigit, Abdurrahman; Aksel, Nimet; Ozlu, Tevfik
Introduction:The aim of our study is to investigate the etiological distribution of ILD in Turkey by stratifying the epidemiological characteristics of ILD cases, and the direct cost of initial diagnosis of the diag-nosed patients. Material-Method: The study was conducted as a multicenter, prospective, cross-sectional, clinical observation study. Patients over the age of 18 and who accepted to participate to the study were included and evaluated as considered to be ILD. The findings of diagnosis, examination and treatment carried out by the cent-ers in accordance with routine diagnostic procedures were recorded observationally. Results: In total,1070 patients were included in this study. 567 (53%) of the patients were male and 503 (47%) were female. The most frequently diagnosed disease was IPF (30.5%). Dyspnea (75.9%) was the highest incidence among the presenting symptoms. Physical examination found bibasilar inspiratory crackles in 56.2 % and radiological findings included reticular opacities and interlobular septal thickenings in 55.9 % of the cases. It was observed that clinical and radiological findings were used most frequently (74.9%) as a diagnostic tool. While the most common treatment approaches were the use of systemic steroids and antifibrotic drugs with a rate of 30.7% and 85.6%, respectively. The total me-dian cost from the patient's admission to diagnosis was 540 Turkish Lira. Conclusion: We believe that our findings compared with data from other countries will be useful in showing the current situation of ILD in our country to discuss this problem and making plans for a solution.
Summary of Consensus Report on Preoperative Evaluation
(Bilimsel Tip Publishing House, 2015) Ozkan, Metin; Kirkil, Gamze; Dilektasli, Asli Gorek; Sogut, Ayhan; Sertogullarindan, Bunyamin; Cetinkaya, Erdogan; Kovan, Tezay