Browsing by Author "Ceyhan, Dogan"

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Causes of Visual Impairment in the Van City Area According To the Health Committee's Reports
(Turkish Ophthalmological Soc, 2012) Ceyhan, Dogan; Yasar, Tekin; Demirok, Ahmet; Cinal, Adnan; Esmer, Oktay; Batur, Muhammed
Purpose: In this study, disability reports of the Health Committee of the Hospital of the Yiiziincii Yil University School of Medicine will be evaluated. The demographic characteristics, causes and degree of visual loss, visual system impairment rating and whole body impairment rating of the people with visual impairment will be determined. Material and Method: Health committee disability reports of our hospital, between September 2006 and August 2010, were evaluated. Relevant variables of each patient were recorded and evaluated. Results: 415 health committee reports for visual impairment were found to be prepared during the period of the study. One hundred fifty three (36,9%) of the cases were female and 262 (63.1%) were male and the mean age was 41.8 +/- 22.4 years. The most frequent causes of visual impairment were macular diseases, evisceration and phitisis, amblyopia, optic nerve diseases, degenerative myopia, acquired corneal and hereditary retinal diseases. The patients who had a disability report had a mean of 41.69 +/- 25.92% visual system impairment rating and 60,76 +/- 24,67% whole body impairment rating. Discussion: This research was planned for contributing to the epidemiologic information about visual impairment in our country. This data may serve to compute the cost of visual disability reports. The information is also expected to contribute to determine the causes and measures for the prevention of diseases and conditions leading to visual disability.
Color Vision and Health Committee Procedures
(Turkish Ophthalmological Soc, 2011) Ceyhan, Dogan; Yasar, Tekin
Besides the diagnosis, follow-up and treatment of some ophthalmic pathologies, color vision examination is used to determine the eligibility for certain professions. Color vision is affected by factors, such as genetic structure of the person, characteristics of the eye and some mental processes, which have not been elucidated exactly yet. Therefore, there is no test which can be easily applied and can evaluate in details and "measure" the color vision ability. Screening tests like Ishihara, which are common in Turkey, do not range the exact color vision ability of the people. In health committees of the hospitals, the necessity to determine conditions like "color blindness/dyschromatopsia" with these tests, makes color vision evaluation harder. When supported by some other color vision tests, the Ishihara test becomes more useful in assessing color vision. Including the terminology, the standards for examination and evaluation of color vision can be further improved in Turkey; thus, the examinations for eligibility for occupation and driving license can be more appropriate for the conditions of the country. This review was intended to make proposals for improvement of color vision examinations and practices for eligibility for some occupations.
Could Visual Impairment in the Pediatric Age Group Be Reduced
(Turkish Ophthalmological Soc, 2013) Ceyhan, Dogan; Yasar, Tekin; Caglar, Cagatay
Pediatric age is the most important period for preventive eye care services and research. Vision loss in this period could cause a long life without sight and also significant financial and moral losses, in terms of people and society. Rational screening programs may reduce vision loss in childhood and this issue increases the value of the subject. Retinopathy of prematurity, congenital/infantile cataracts and glaucoma, optic nerve and retinal pathologies, refractive errors, amblyopia, and strabismus are the major clinical pictures causing visual loss in childhood. Using the epidemiological data, it could be estimated that every year approximately two to three thousand children suffer an ophthalmologic disease that causes significant visual loss. Regarding the refractive errors and amblyopia, it could be estimated that hundreds of thousands of children need ophthalmological follow-up in the country. For the timely treatment of these pathologies, a couple of short eye examination programs seem more realistic. Childhood vision loss in the country could be reduced, by informing pediatricians and family physicians and by proper guiding of the public opinion. Effective eye screening could be achieved with the implementation of simple methods like red reflex/Bruckner test with ophthalmoscopy, or simultaneous ( binocular) retinoscopy and ophthalmoscopy of both eyes. Screening programs could be spread throughout the country by appropriate training of the physicians in the health institutions of the country. Screening programs will contribute to reduce the rate of visual disability by disseminating ophthalmologic practices throughout the country.
A Novel Heterozygous Deletion Within the 3′ Region of the Pax6 Gene Causing Isolated Aniridia in a Large Family Group
(Elsevier Sci Ltd, 2009) Bayrakli, Fatih; Guney, Ilter; Bayri, Yasar; Ercan-Sencicek, Adife Gulhan; Ceyhan, Dogan; Cankaya, Tufan; Gunel, Murat
Paired box gene 6 (PAX6) is the causative gene of aniridia. it is a dominantly inherited eye abnormality characterized by partial or complete absence of the iris. The PAX6 gene is located on chromosome 11 p13 and contains 14 exons. It is expressed mainly in the developing eye and central nervous system. Submicroscopic copy number variations are common in the human genome. Submicroscopic deletions may cause several human diseases, either by disrupting coding sequences or by eliminating regulatory elements essential for expression of the gene in question. Over the past several years, array-based comparative genomic hybridization has become an increasingly useful too] for both identifying normal cytogenetic variations and characterizing chromosomal abnormalities associated with developmental delays and cancer. Our results support the notion that assessing copy number variation of the PAX6 gene itself and also of flanking regions, may contribute to the molecular diagnosis of aniridia. (C) 2009 Elsevier Ltd. All rights reserved.
Ophthalmologic Screening in a School for the Hearing Impaired in Turkey
(Ortadogu Ad Pres & Publ Co, 2011) Ceyhan, Dogan; Idil, Aysun; Ozdemir, Oya; Caliskan, Deniz
Objective: The aim of this study was to screen the ophthalmic disorders in a school for the hearing impaired and to draw the attention to the necessity of early educational and career modifications of children with Usher syndrome. Material and Methods: The study population was 208 of 214 students in a school for hearing impaired in Ankara; ages ranged from 7 to 19 years. All students underwent an ophthalmologic examination, including uncorrected and corrected visual acuity measurement, assessment of manifest refraction, slit lamp biomicroscopy and fundoscopy. Cover/uncover test was done to detect a tropia of more than 10 prism diopters. Students with an ophthalmic pathology were invited for a detailed eye examination. Chi square test and binary logistic regression analysis were used for statistical analysis. Results: Of the 208 students, 72 (34.6%) had an ocular abnormality. One hundred eighty four (88.5%) children presented with normal fundus findings. Of the 24 patients with an ophthalmoscopic finding, twelve (5.8%) were diagnosed with retinitis pigmentosa, three with Waardenburg syndrome and four with atypical retinal pigmentary changes. Female gender (p<0.05) and the presence of a refractive error (p<0.0001) were significandy correlated with the existence of ophthalmoscopic findings. Conclusion: Early referral to an ophthalmic examination is mandatory for the hearing impaired children. In previous studies, higher frequency of ophthalmic disorders in the hearing impaired population had been reported; present study also emphasizes the necessity of educational and career modifications in hearing impaired children with retina pathologies. Detection and early intervention of ophthalmologic abnormalities is important for the normal development of cognitive and social skills and also for education and career modifications.
Results of Different Refractive Error Measurement Methods
(Turkish Ophthalmological Soc, 2011) Ceyhan, Dogan; Bozca, Tarik; Konca, Reyhan; Keskin, Siddik
Purpose: The aim of this study was to compare the reliability of different methods of objective refractive error measurement. Material and Method: Cycloplegic refractive errors of sixty-seven eyes of thirty-six male patients were measured. Subjects were chosen between the patients who had refractive errors more than 2.00 diopters of myopia, hyperopia or astigmatism. Spherical and cylindrical errors as well as spherical equivalents were measured with two different autorefractors and a retinoscope. Repeated measures analysis of variance and Tukey's multiple comparison test were used for the statistical analysis of refractive error measurements. Results: The mean and standard deviation values of spherical refractive error were 6.94+/-3.43 with retinoscopy, 7.21+/-3.29 for autorefractor 1, and 7.94+/-3.44 for autorefractor 2. The spherical equivalents were 7.50+/-3.43 for retinoscopy, 7.93+/-3.38 for autorefractor 1, and 8.83+/-3.64 for autorefractor 2. These values show that statistically and clinically significant differences existed between autorefractors 1 and 2 as well as between autorefractor 1 and retinoscope (p< 0.05). Discussion: The results of this study demonstrate that different measurement methods and instruments may yield different values of refractive errors, which may cause wrong decisions about the value of objective refraction. Standardization of measurement methods should be established to obtain valid, accurate and reliable results and, especially for occupational requirements, subjective refraction should gain wider acceptance as " gold standard" method.
Topiramate Induced Bilateral Angle-Closure Glaucoma: Low Dosage in a Short Time
(Mary Ann Liebert inc, 2012) Caglar, Cagatay; Yasar, Tekin; Ceyhan, Dogan
Purpose: The aim of this article is to create awareness among medical colleagues regarding the severe ophthalmic side effects associated with topiramate use. Methods: A case of severe acute bilateral angle closure glaucoma with visual blurring after oral topiramate therapy. Results: This case was successfully managed by discontinuing topiramate and by starting anti-glaucoma medication. Intraocular pressure, acute transient myopia, and anterior chamber depth were normalized. Conclusions: It is important for clinicians to recognize these conditions and educate patients about these serious adverse effects when prescribing topiramate.