Browsing by Author "Ceylan, A."

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An Analysis of Corrosive Substance Ingestion of Children in Eastern Turkey
(2008) Melek, M.; Edirne, Y.; Çobanoǧlu, U.; Ceylan, A.; Can, M.
In this study, we aimed at describing corrosive substance ingestion and related problems in Eastern Turkey. This type of injury is still a serious problem to be given a careful attention in our country like the other developing countries. The charts of children managed in our hospital with corrosive substance ingestion in the period of 1996- 2008 were evaluated retrospectively. Gender, age, ingested substance and the volume, symptoms, morbidity of caustic injury were considered in the analysis of the charts. We had 40 male and 35 female cases. 82% of children were under 5 years old. Mean age was determined as approximately 3.5 years. Bleach was the most common corrosive substance received and it was followed by hydrochloric acid. The volume of the ingested substance varied between 1-100 ml. The volume could not be estimated in 36 children. It was determined that 54% of ingested corrosive substance was in its original package. Twenty-five cases ingested the substance from food or drink containers that was stored somewhere in the kitchen. Five children had developed esophageal strictures. They were included in esophageal dilatation program. In our country the morbidity of caustic esophageal burn is still a problem that should be involved. Attention to the storage conditions and secured bottle cap seems to be the easiest and simplest way to prevent corrosive substance ingestion.
Baller-Gerold Syndrome Associated With Dextrocardia
(Medecine Et Hygiene, 2011) Ceylan, A.; Peker, E.; Dogan, M.; Tuncer, O.; Kirimi, E.
Baller-Gerold syndrome associated with dextrocardia: Baller-Gerold Syndrome (BGS) is a rare autosomal recessive disorder that is apparent at birth. The disorder is characterized by distinctive malformations of the skull and facial area and bones of the forearms and hands. We report a 4 year old boy in whom the clinical features of craniosynostosis and bilateral absent thumbs and radii led to a diagnosis of Baller-Gerold syndrome. Physical examination revealed that the heart was localized to the right side. Echocardiography confirmed dextrocardia. Dextrocardia has not previously been reported with Baller-Gerold syndrome. To the best of our knowledge, this is the first reported case of Baller-Gerold syndrome associated with dextrocardia.
Budd-Chiari Syndrome in a Patient Heterozygous for Both Factor V Leiden and the G20210a Mutation on the Prothrombin Gene
(Schattauer GmbH, 1999) Oner, A.F.; Arslan, S.; Caksen, H.; Ceylan, A.
Childhood Brucellosis: a Retrospective Study of 103 Cases
(1999) Arslan, S.; Oner, A.F.; Caksen, H.; Cesur, Y.; Ceylan, A.; Atas, B.; Abuhandan, M.
In this study, the clinical and laboratory findings of 103 patients who were followed in our hospital with the diagnosis of brucellosis in our hospital were reviewed retrospectively. Our purpose was to determine the initial drug combination used in its treatment, and to stress the importance of this disease as a public health problem in Turkey, particularly in the Van region. Of the 103 patients, 52 were female and 51 were male. The patients' ages ranged from 20 months to 16 years (mean 8.31 ± 3.58 years). The most observed symptoms were fever (55.3%), arthralgia (53.3%), malaise (41.7%) and loss of appetite (30%). The most observed signs were hepatosplenomegaly (22.5%), hepatomegaly (20.5%), arthritis (17.4%) and splenomegaly (15.5%). Anemia was present in 18 (17.4%) patients, leukopenia in eight (7.7%), and leukocytosis in 15 (14.5%). Erythrocyte sedimentation rate was studied in 84 (81.5%) patients; it was higher than 20 mm/hour in 52 (61.9%) patients. Liver function tests were studied in 55 (53.3%) patients; AST (aspartate aminotransferase) and ALT (alanine amino transferase) were abnormal in 31 (56.3%) and in 55 (53.3%) patients respectively. Brucella agglutination test was 1/160 or higher in all patients; it was ≥1/320 in most patients (83.5%). In the treatment, 12 types of drug combination used, primarily rifampin + co- trimoxazole, rifampin + tetracycline and streptomycin + co-trimoxazole. All except seven patients were successfully treated with the initial drug combination used. For the these seven patients, the initial drugs were changed for different drug regimens. There was no difference between the drug combination and recovery ratio (p>0.05). No relaps were noted.
Chondrodysplasia Punctata Associated With Tetralogy of Fallot in a Newborn Infant
(Medecine Et Hygiene, 2010) Akgun, C.; Akbayram, S.; Tuncer, O.; Taskin, G.; Ceylan, A.
Comparison of Various Treatments in Childhood Brucellosis
(2006) Yuca, S.A.; Ceylan, A.; Çaksen, H.; Kirimi, E.; Yilmaz, C.; Bay, A.
The aim of this study was to evaluate the effectiveness of different drug combinations for treatment of brucellosis in children. Sixty children (mean age 9.2 ± 3.1 years, range 10 months to 15 years) were treated with four different drug combinations. The diagnosis of brucellosis was established by positive serum agglutination titer, and/or the isolation of Brucella species from blood cultures. The most frequent findings were fever and arthritis in 12 (20%) and 13 (21.6%) patients respectively. The children under 8 years old comprised Group 1 and 2, and older than 8 years comprised Group 3 and 4 according to treatment regimens. Nine patients (Group 1) were treated with trimethoprim-sulfamethoxazole (TMP-SMZ) for 45 days plus ceftriaxone for 5 days and, rest nine patients (Group 2) were managed with TMP-SMZ for 45 days plus gentamicin for 5 days. Twenty-one patients (Group 3) were managed with doxycycline for 45 days and ceftriaxone for 5 days and, other 21 (Group 4) patients were managed with doxycycline for 45 days and gentamicin for 5 days. All patients recovered. Relapse and improvement rates were similar for all groups (P >0.05). Each regimen was effective in the treatment of childhood brucellosis. Using cheaper drugs such as doxycycline and gentamicin in children 8 years of age and older, and TMP-SMZ and gentamicin in children 7 years of age or younger for the treatment of brucellosis in children is a practical and useful approach in our region and in the developing countries. © 2006 - IOS Press and the authors.
Congenital Myasthenic Syndrome: a Case Report
(Medecine Et Hygiene, 2011) Ceylan, A.; Tuncer, O.; Sayin, R.; Peker, E.; Caksen, H.; Sari, S.
Congenital myasthenic syndrome: a case report: Congenital myasthenic syndromes (CMS) are diseases of the neuromuscular junction. They usually belong to the disease groups that begin in the infantile or childhood period and carry genetic characteristics. The following is important in establishing the diagnosis of this disease: clinical findings, electromyography, genetic tests, determination of serum acetylcholine receptor antibodies. Acetylcholine esterase inhibitor drugs are used in treatment of CMS. A seven-month old male patient was brought to our department with the complaints of difficult breathing, falling of the eyelids and swallowing difficulty. With clinical and laboratory findings, he was diagnosed with congenital myasthenia and treatment was started. CMS should be suspected in patients with no pathological findings on the physical examination, and normal chest X-rays.
Drug Allergy
(1999) Ceylan, A.; Cesur, Y.; Rastgeldi, L.
The numbers of drugs used for therapy are increasing every day and the risk of allergy is rising. Medicines which have different chemical structure cause a lot of reactions. Allergic symptoms related to the drugs change from simple to fatality. Especially, peniciline allergy may be fatal. The drug allergies is reviewed summarize in this article.
Food-Borne Botulism Cases in Van Region in Eastern Turkey: Importance of Electromyography in the Diagnosis
(2003) Anlar, O.; Irmak, H.; Tombul, T.; Akdeniz, H.; Caksen, H.; Kose, D.; Ceylan, A.
Objectives: Food-borne botulism is an acute form of poisoning that results from ingestion of a toxin produced by Clostridium botulinum. Botulism toxin causes its major effect by blocking neuromuscular transmission in autonomic and motor nerve terminals. Methods: In this study, we present the features of eleven cases of food-borne botulism admitted to our hospital in 2001. All of the cases were caused by home-prepared foods; green beans. In these cases, the main symptoms and signs were generalized muscular weakness, dry mouth, dysphagia, dispnea and diplopia. Electrophysiological studies were performed on four patients. Results: Motor conduction studies showed that compound muscle action potentials were decreased with normal latencies and conduction velocities. The needle electromyography showed signs of denervation potentials like fibrillation and positive waves in four patients. Repetitive nerve stimulation with high frequency (20 Hz) induced an increment close to 100% in the amplitudes in 2 of 4 patients. Conclusion: Although toxin could not be detected in the patients, the electromyographic findings supported our diagnosis. We concluded that electromyography has an important role in diagnosis of botulism, especially in the condition that serologic tests are negative or cannot be performed.
Giant Cavernous Hemangioma in Two Neonates With Kasabach-Merritt Syndrome: Successful Management With Interferon Alpha and Prednisolone
(Blackwell Publishing, 2008) Kirimi, E.; Tuncer, O.; Akgun, C.; Ceylan, A.
Joubert Syndrome Associated With Patent Ductus Arteriosus in a Newborn Infant
(Medecine Et Hygiene, 2009) Peker, E.; Kirimi, E.; Sal, E.; Ceylan, A.; Ustyol, L.; Caksen, H.
Rubella Seroprevalence in Adolescent Girls in the Eastern Region of Turkey
(2002) Çaksen, H.; Ceylan, A.; Ceylan, N.; Arslan, S.; Öner, A.F.; Kirimi, E.; Gölbasi, C.
Thanatophoric Dysplasia Type I: Case Report
(Blackwell Publishing, 2008) Kirimi, E.; Bektas, S.; Ceylan, A.; Gulmehmet, F.
Tibial Osteomyelitis Following Intraosseous Infusion: a Case Report
(2004) Dogan, A.; Irmak, H.; Harman, M.; Ceylan, A.; Akpinar, F.; Tosun, N.
Fluids, medications, and blood products can be rapidly administered via intraosseous infusion under emergency conditions, particularly to pediatric patients aged from 0 to 2 years. A five-month-old infant who had been hospitalized with a diagnosis of sepsis developed swelling and hyperemia at the infusion site 10 days after an intraosseous infusion in the right proximal tibia. Physical examination showed a serous discharge from a fistula on the anteromedial side of the right proximal cruris. Plain radiographs demonstrated periosteal reaction in the right tibia and osteolytic areas in the proximal metaphysis. With a diagnosis of acute osteomyelitis, drainage and medullary irrigation were performed and parenteral antibiotic treatment was initiated. Cultures from the surgical site yielded Candida albicans, upon which fluconazole (8 mg/kg) treatment was administered for four weeks. A complete clinical and radiographic improvement was observed at the end of a 12-month follow-up.
Use of Intravenous Megadose Corticosteroid in a Child With Thrombocytopenic Purpura Due To Mumps
(2001) Öner, A.F.; Çaksen, H.; Arslan, Ş.; Odabas, D.; Özer, R.; Ceylan, A.