Browsing by Author "Ceylan, E."

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Antioxidant Vitamins and Microminerals in Cows With Foot-And Disease
(Agricultural Research Communication Centre, 2014) Yoruk, I. H.; Tanritanir, P.; Dede, S.; Ceylan, E.; Ragbetli, C.
Foot and-mouth disease (FMD) is an acute, highly contagious inflammatory viral disease of domestic and wild animals which causes decrease in productivity and lead to mortality. This study was conducted to investigate the levels of copper, zinc, magnesium and iron, alpha-tocopherol, vitamin D-3, vitamin C and lipid peroxidation in cow with foot-and-mouth disease. Sixty native black cows infected by foot-and-mouth disease and twenty healthy controls were selected for the study after clinical and serological examination. In the diseased animals, the malondialdehyde (p<0.00) and-copper (p<0.001) levels were increased while the vitamin C, alpha-tocopherol (p<0.001), vitamin D3 (p<0.05) magnesium (p<0.001) and iron (p<0.005) levels were decreased relative to controls. Although the zinc level was not changed, the Cu/Zn ratio was elevated in the diseased group. The obsereved changes may be the result of secondary infections due to suppressed immune system and losses of tissue and mucosa associated with foot-and-mouth disease.
The Effect of Draxxin Treatment on Blood Gases Levels of Montofon Calves With Pneumonia
(2010) Tanritanir, P.; Raǧbeth, C.; Deǧer, Y.; Ceylan, E.
The purpose of this study was to investigate examine changes in venous blood gases of Brown Swiss calves with pneumonia. For this purpose, 30 calves exhibiting having clinical sings of pneumonia and 20 healthy calves were used. Venous blood samples were collected from the healthy and diseased calves before and after treatment with Draxxin (tulathromycin-Pfizer) in order to determine pH, pCO2, pO2, tCO2 and HCO3 levels by Blood Gas Analyzer. Compared to the controls group, in the diseased animals, there was a significant increase of pCO2 and HCO3 levels, together with a significant decrease of pH and pO2 levels (p<0.05). One week after treatment, pH, pCO2 and HCO3 levels were significantly changed. Despite this change, these levels were still similar with other groups. Also, the venous blood pO2 level went back increased to be statistically the same as the healthy animals. The tCO2 level was not found statistically different among the three groups. It is concluded that pneumonia in calves impairs gas exchange, but that gas exchange improves rapidly after treatment. © 2010 Academic Journals Inc.
Effect of Streptozotocin on Biochemical Parameters in Rats
(Chemical Publishing Co., 2010) Ragbetli, C.; Ceylan, E.
This study was carried out to investigate whether streptozotocin induced diabetic rats could effect some of serum biochemical parameters. Twenty Sprague-Dawley albino rats were divided into two experimental: Control (50 mg/kg SF) and streptozocin (60 mg/kg), Control rats were given only physiological saline (50 mg/kg). Serum glucose, AST, ALT and cholesterol levels of rats were determined after treatment of 1, 3 and 6 h, while the level of glucose, aspartate amino transferase (AST) and alanine amino transferase (ALT) were increased and cholesterol level was decreased. It is concluded from the experimental study that streptozocin (60 mg/kg) may increase of serum glucose, AST, ALT levels and cause diabet in rats.
The Effect of Tulathromycin Treatment on Biochemical Parameters in Montofon Calves With Pneumonia
(Academic Journals inc, 2010) Ragbetli, C.; Ceylan, E.; Tanritanir, P.
The purpose of this study is to examine changes in some biochemical parameters of treatment with tulathromycin in Montofon calves with pneumonia. For this purpose, 30 claves exhibiting clinical sings of pneumonia with fever, cough, lack of appetite, nasal flaring, mandibular lymph node enlargement dyspnea and nasal discharge were studied. A control group of 20 healthy calves was also studied. Blood samples were collected from the healthy and diseased calves before and after treatment with Draxxin (Tluthromycin-Pfizer). Compared to the control group Ca, K, total bilirubin, albumin, urea levels were affected (p<0.001) and Na (p<0.05) in the diseased animals and total protein, ALP, Glucose, Creatin levels were not affected in the diseased animals (p>0.05). Single dose tulathromycin therapy was characterized by significantly fewer treatment days, a higher response rate, significantly better reduction of pyrexia and fever and other pneumonia symptoms in calves requiring treatment.
Effects of Onion Juice Administration on Electrocardiogram in Dogs
(2009) Ceylan, E.; Aytekin, I.; Keles, I.; Altug, N.
The purpose of this study, was to investigate the effects of Onion Juice Administration (OJA) on Electrocardiogram (ECG) in dogs. Five clinically healthy street dogs were used in this study. Onion juice was given through oro-gastric tube of 400 g onion kg-1 body weight dose in 500 mL water. Blood samples were collected at just before and after (6, 12 and 24th h) Onion Juice Application (OJA). PCV, heart beats counts and electrocardiograms of the animals in the same time were determined. PCV values gradually, decreased and these decreases were significant at 6th (p<0.01), 12th (p<0.01) and 24th (p<0.001) h after OJA. Bradicardia was observed at 6th (p<0.05) and 12th (p<0.001) h after OJA whereas tachycardia was observed at 24th h (p<0.001). Before and 6th h after OJA heart rates were within normal limits in this study. First degree heart block occurred 12th h after OJA and aritmia was obvious at this time. P-Q interval also increased. Bradicardia developed in some derivations. The mean heart rate was approximately 60 beats min-1. Twenty-four hours after OJA tachycardia developed and the mean heart rate was 130 beats mm-1. In summary, OJA caused the anemia (reduction in the PCV values,) 1st degree heart block, tachycardia in dogs. Further studies on this issue, might be helpful for determining the effects of OJA on ECG in different species. © Medwell Journals, 2009.
The Efficacy of Moxidectin Against Gastrointestinal Nematode Infections in Goats
(2009) Ragbetli, C.; Ceylan, E.; Tanritanir, P.
The aim of this study was to examine the efficacy of rnoxidectin treatment on goats naturally infected with gastrointestinal nematodes in Van region, Turkey. Two hundred and forty goats infected with gasterointestinal parasites were treated with 0.2 rug kg-1 moxidectin (Cydectin, Abfar), subcutaneously. Ten randomly selected goats were not treated and allocated as a control group. Faecal samples were examined for gastrointestinal parasites qualitatively and quantitatively (EPG) in 0th, 7th and 14th days of treatment Larvae of the parasite species of Ostertagia, Haemonchus, Nematodirus and Trichostrongylus were detected in the coprocultures of the infected animals performed before treatment. It was observed that moxidectin was 100% effective against the gastrointestinal nematodes. © 2009 Academic Journals Inc.
Enhancement of the Glucose Metabolism and the Reverse Cholesterol Transport by a Peroxisome Proliferator Receptor Α (Pparα) Agonist Included in the Fasciolosis Treatment in Naturally Infested Sheep
(Ecole Nationale veterinaire Toulouse, 2013) Yuksek, N.; Altug, N.; Denizhan, V.; Ceylan, E.; Agaoglu, Z.
The purpose of this study was to investigate the effects of PPAR alpha agonist on metabolic parameters in naturally Fasciola-infected sheep. Twenty sheep with fasciolosis were allotted in 2 equal groups according to the received treatment (triclabendazole/levamisole in the group I and triclabendazole/levamisole + PPAR alpha agonist (2-methyl-2-phenoxy-propionic acid) in the group II) and the haematological and biochemical parameters were assessed before the treatment and 7, 14 and 28 days after and were compared to control values determined from 10 healthy sheep. As expected, fasciolosis has induced an anaemia evidenced by low haematocrit and low haemoglobinemia coupled to eosinophilia and to a moderate lymphopenia, severe liver damage characterised by hepatocyte degenerescence (significant increases in serum AST and GDH activities) and bile duct obstruction (significant increases in serum GGT activity and in serum bile acid concentrations) leading to impairement in liver metabolic functions (hypoalbuminemia, marked decreases in serum glucose concentrations and in LDL associated cholesterol concentrations). All the heamatological and biochemical alterations were at least partially alleviated by the antihelminthic treatment except the serum triglyceride concentrations which have continued to decrease during the post-treatment period and the total cholesterol and HDL associated cholesterol concentrations which have markedly increased, particularly when sheep were also treated with the PPAR alpha agonist. These results clearly demonstrated the severe metabolic liver impairment occurring during fasciolosis in sheep and the beneficial effects of the PPAR alpha agonist on the correction of the negative energy balance, particularly by promoting the reverse cholesterol transport.
Evaluating the Effect of the Treatment of Doramectin on Some Biochemical Parameters in Goats Naturally Infected With Gastrointestinal Nematodes
(Academic Journals inc, 2010) Ceylan, E.; Ragbetli, C.; Tanritanir, P.
The aim of this study was to investigate the therapeutic effect of doramectin applied once in an optimum dose on stomach-intestine nematodes on goats naturally infected with gastrointestinal nematodes. Alto to study the effect of the doramectin application on the clinically important biochemical parameters, electrolytes, minerals, vitamin B-12 levels and enzyme activities of goats were affected or not after anthelmentic drug application. For this purpose, the stools in 45 goals between 1-3 year were chosen in Van province and subjected to Fulleborn saturated salt solution method. Thirty goats with gastrointestinal nematodes constituted treatment group and they were doramectin applied (group I). Other 15 goats with gastrointestinal nematodes chose as control group (group II) was not Doramectine applied. Taking stool samples goats with Doramectin treatment and from control group on the 0, 7 and 14 days of application in gram stools, the number of eggs (EPG) were analyzed by modified McMaster method and treatment efficiency was a investigated. After coprocultures, goats were determined to be infected with Trichostrongylus sp., Nematodirus sp., Ostertagia sp., Marshallagia sp., Haemonchus sp. and Oesphagostomum sp. The results demonstrated that Fe, Albumin and hemoglobin levels statistically increased in treatment group in comparison with control group (p<0.05); a significant change in IBP, Ferritin, ALT, AST, total protein, P, Ca, Na and K levels was not observed and minor increases along with the treatment related to time in vitamine B-12, ALP and Mg levels occurred. It was concluded that in goats, one dose of 0.2 mg kg(-1) of subcutaneous doramectin was efficient 100% and no side-effect was observed.
Evaluation of Analgesic and Anti Inflammatory Activity of Pimpinella Anisum Fixed Oil Extract
(indian veterinary Journal, 2006) Tas, A.; Ozbek, H.; Atasoy, N.; Altug, M. Enes; Ceylan, E.
Pimpinella anisum is a member of the Umbelliferae and is found in the northeastern Anatolia (Zeybek, 1960). In Turkish folk medicine, Pimpinella species have several uses such. as analgesic, anti-inflammatory, appetizing, hypnotic, antispasmodic, expectorant,. antibacterial and hepato-protective. Seeds of P. anisum contains 1.5 - 2.0 % essential oil, 10-20 % fixed oil, 18 % protein. No reports are available on the evaluation of this plant for possible anti-inflammatory and analgesic activity: In this study, fixed oil of P. anisum was investigated for anti-inflammatory activity using carrageenan-induced rat paw oedema test (Winter et al., 1962) and analgesic activity with a tail-flick apparatus using a method initially described by D'amour and Smith (1941).
Investigation of the Effects of Carrying Heavy Load on Prooxidation/Antioxidant Status and Vitamin D3 in Healthy Horses
(Academic Journals inc, 2009) Ceylan, E.; Dede, S.; Deger, Y.; Yoeruek, I.
The aim of the study was to investigate the effect of carrying heavy load for a long time on lipid peroxidation (MDA: malondialdehyde), NO2 (nitrite), NO3 (nitrate), antioxidants (GSH: reduced glutathione, retinol, alpha-tocopherol) and vitamin D-3 in healthy horses. Blood samples from seventeen native 3-5 years age and 450-500 kg live weight Anatolian horses carried a load which comprised at least 30% of their body weight and for 4 h on mountainous terrain (hard working) were evaluated. Blood samples were collected in the morning before the animals started to carrying load and immediately after they finished carrying (working). It is observed that the level of MDA, NO2 and NO3 increased significantly (p<0.05) after working. While GSH concentration, increased after working; levels of retinol, alpha-tocopherol and vitamin D-3 levels decreased significantly (p<0.05). On the other hand, the vitamin D-3 levels were affected by hard working as other lipid soluble vitamins. There were a correlation between the physiological response to hard-working and some oxidant markers in healthy-hard working horses. These observations provide evidence that hard-working increases oxygen consumption and cause a disturbance of intracellular prooxidant-antioxidant homeostasis.
Prevalence of Chronic Bronchitis-Asthma Symptoms in Biomass Fuel Exposed Females
(Japanese Society for Hygiene, 2003) Uzun, K.; Özbay, B.; Ceylan, E.; Gencer, M.; Zehir, I.
Objectives: We investigated whether exposure to biomass fuel is a potential risk factor for chronic bronchitis and asthma among females in rural area in Van (east Turkey). Methods: The effect of indoor pollution producing various respiratory symptoms was studied in 177 females. Of these, 90 were those who used biomass fuel and 87 were nonusers of biomass fuel. A part of the European Community Respiratory Health Survey quastionnaire and British Medical Research Council questionnaire were used. Results: Asthma related symptoms (AS) (wheezing, and combination of wheezing without a cold and wheezing with breathlessness) were reported in 63.3% of those who used biomass fuel, and in 12.9% of nonusers (p<0.0001). The use of asthma medication was reported as 3.3% of biomass fuel users, and in 2.7% of nonuser (p>0.05). Long term cough and/or morning cough together with sputum (chronic bronchitis symptoms (BS) was reported as 58.9% in the user group, and 29.4% in the nonuser group (p<0.0001). Significant differences in AS and BS were found between biomass fuel user and nonuser groups in the rural area. Conclusions: The results of this study showed a significant association between symptoms of chronic bronchitis-asthma and biomass fuel usage in females living in a rural area.
Pseudopericarditis in a Cow Caused by Theileriosis - a Case Report
(2003) Keleş, I.; Alptekin, I.; Atasoy, N.; Çinar, A.; Dönmez, N.; Ceylan, E.
Pseudopericarditis has been used to describe jugular engorgement and oedema of the brisket and ventral abdominal wall. Similar symptoms can be seen in cattle with traumatic pericarditis. Pressure caused by tumours, abscesses, Echinococcus cysts, swollen lymph nodes resulting from tuberculosis and leukosis, one-sided pleuritis and diaphragmatic hernia to the base of cranial and caudal vena cava returning blood to the heart have been reported to cause pseudopericarditis in cattle. These mediastinal lymph nodes may also be swollen due to theileriosis and cause pressure on the v. cava. This study aims to describe the clinical, haematological and electrocardiographical findings of a pseudopericarditis case in a cow caused by theileriosis, and to add the disease into the aetiology of pseudopericarditis.
Pumice-Supported Ruthenium Nanoparticles as Highly Effective and Recyclable Catalyst in the Hydrolysis of Methylamine Borane
(Elsevier Ltd, 2024) Dayan, O.; Kilicer, A.; Bulut, A.; Ceylan, E.; Tayfun, U.; Uzun, O.; Yurderi, M.
Pumice-supported Ruthenium nanoparticles were prepared by the impregnation-reduction method and investigated for hydrogen production in the methylamine borane (MeAB) hydrolysis reaction. The catalytic properties of this highly active Ru/Pumice catalyst were analyzed in terms of temperature (from 298 K to 328 K), substrate ([MeAB]) amount, metal loadings ([Ru]), and recyclability. In addition, the characterization of the obtained catalyst was investigated by inductively-coupled plasma optical emission spectroscopy (ICP-OES), powder X-ray diffraction (P-XRD), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS) imaging/spectroscopic techniques. The Ru/Pumice catalyst showed a superior initial TOF value (83.15 min−1 or 4989.30 h−1) in the MeAB hydrolysis reaction, and also the activation parameters (Ea, ΔH#, and ΔS#) from the Arrhenius and Eyring-Polonyi equations were found to be 42.4 kJ/mol, 39.8 kJ/mol, and −110.07 J/mol.K, respectively. © 2022 Hydrogen Energy Publications LLC
The Seroprevalence of Canine Brucellosis in Shepherd Dogs
(KAFKAS UNIVERSITY, 2009) Tanritanir, P.; Ceylan, E.; Berktaş, M.
Serum Biochemical Profile and Protein Fractions in Cattle With Theileriosis
(Ecole Nationale veterinaire Toulouse, 2014) Dede, S.; Altug, N.; Deger, Y.; Ozdal, N.; Ceylan, E.
Theileriosis encountered frequently in Van region and causes huge economic losses in cattle, sheep and goats. This study was carried out to examine the serum biochemical profile and serum protein fractions, determined before and 7 days after buparvaquone treatment, in 28 cattle, diagnosed to be infected with T. annulata and in 15 healthy control animals from the same region. The ALT (alanine amino transferase) and ALP (alkaline phosphatase) activities and the concentrations of bilirubin and urea were markedly increased in sera from infected animals whereas the concentrations of glucose, minerals (Na, K and Ca), total proteins, albumin and of a-globulins and the albumin/globulin (A/G) ratios were significantly depressed compared to the controls. In addition, buparvaquone treatment succeeded in alleviating the serum biochemical anomalies. These results show that liver and kidney failures occur during theileriosis leading to a global protein deficiency and that serum biochemistry and serum protein analysis may allow biochemical evaluation of treatment.