Browsing by Author "Cifci, Adem"

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Coexistence of the Poems Syndrome With Hepatitis B: a Rare Case Report
(Springer Wien, 2016) Celik, Yilmaz; Aslan, Mehmet; Sayin, Refah; Cifci, Adem; Canbaz, Esra Turan; Kucukoglu, Mehmet Emin; Dulger, Ahmet Cumhur
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) is a rare multisystemic disease of unknown pathogenesis. Proinflammatory and proangiogenic cytokines play important roles in its pathogenesis. POEMS syndrome is a rare cause of ascites. Until now, the coexistence of POEMS syndrome and hepatitis B has not been reported. In this case report, we present a 48-year-old male patient who presented with malaise, fatigue, diarrhea, and abdominal swelling. Organomegaly, endocrinopathy, ascites, skin changes, and polyneuropathy were identified, and we arrived at a diagnosis of POEMS syndrome. The patient was administered methylprednisolone 64 mg/day, lamivudine 100 mg/day, calcium 1.5 g/day, and calcitriol 0.5 A mu g/day. The patient's clinical manifestations had moderately resolved at the follow-up visits. At the end of 6 months of follow-up, his ascites was minimally reduced, and his neurologic manifestations had not lessened. The present case shows that accurate diagnosis is required for the management of patients with coexisting POEMS syndrome and hepatitis B.
Hashimoto's Thyroiditis Associated With Idiopathic Portal Hypertension
(Medycyna Praktyczna, 2013) Dulger, Ahmet C.; Aslan, Mehmet; Olmez, Sehmus; Yavuz, Alpaslan; Cifci, Adem; Kalkan, Nurhan O.; Demirkiran, Davut
Liver Hepatotoxicity Associated With Pantoprazole: a Rare Case Report
(Springer Wien, 2014) Aslan, Mehmet; Celik, Yilmaz; Karadas, Sevdegul; Olmez, Sehmus; Cifci, Adem
Hepatotoxicity may occasionally develop over the course of treatment with proton pump inhibitors (PPIs). Although skin reactions, interstitial nephritis, pancytopenia, anaphylaxis, and generalized edema have been reported to be associated with PPIs, hepatotoxicity associated with oral pantoprazole is very rare. In this report, we present a case of hepatotoxicity in a 35-year-old man who received pantoprazole (40 mg/day) for acute gastritis. One week after discontinuation of pantoprazole, his liver function began to improve, and the patient gradually fully recovered. Although this toxicity occurs only infrequently, pantoprazole should be considered as a rare hepatotoxic agent in the literature.