Browsing by Author "Cinal, Adnan"

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Assessment of Corneal Endothelial Cell Density in Patients With Keratoconus Not Using Contact Lenses
(Elsevier Science Bv, 2013) Timucin, Ozgur Bulent; Karadag, Mehmet Fatih; Cinal, Adnan; Asker, Muntecep; Asker, Selvi; Timucin, Damla
Purpose: To assess the corneal endothelial cell density (ECD) in keratoconus patients with no history of contact lens use. Setting: Yuzuncu Yil University, School of Medicine and Van Training and Research Hospital, Department of Ophthalmology, Van, Turkey. Design: Cross-sectional controlled study. Methods: The eyes of 65 patients with the diagnosis of keratoconus with no history of contact lens wear and the eyes of 40 healthy controls were prospectively examined using the Heidelberg Retinal Tomography Rostock Cornea Module (HRT3/RCM). The average ECD from the two groups were then compared. Results: Of the cases with keratoconus, 44(67.7%) were men and 21 (32.3%) were women. The mean age was 20.9 +/- 6.8 (range =10-41) years. Of the controls, 28 (70%) were men and 12(30%) were women. The mean age was 23.9 +/- 5.8 (range = 14-35) years. Of the 65 eyes with keratoconus, 19(29.2%) had mild keratoconus, 21 (32.3%) had moderate keratoconus, and 25 (38.5%) had severe keratoconus. The mean ECD was 2731.6 +/- 303.2 cells/mm(2) in cases with keratoconus and 2664.9 +/- 319.5 cells/mm(2) in controls. There was no difference between the densities (unpaired t-test, P=0.4). No significant relationships were found between the ECD data and central corneal thickness or steepest keratometric. Conclusions: Endothelial cell density was unaltered in keratoconic patients without a history of contact lens use when compared with healthy controls. Change in ECD is independent from the central corneal thickness and the stage of keratoconus. (C) 2012 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.
Assessment of Keratocyte Density in Patients With Keratoconus Not Using Contact Lenses
(Lippincott Williams & Wilkins, 2011) Timucin, Ozgur Bulent; Karadag, Mehmet Fatih; Cinal, Adnan
Purpose: To assess the keratocyte density (KD) in the cornea of patients with keratoconus not using contact lenses. Method: In this pilot study, the eyes (n = 68) of 35 patients with the diagnosis of keratoconus, who did not use contact lenses and the eyes (n = 70) of 35 healthy controls were prospectively examined using the Heidelberg Retinal Tomography Rostock cornea module (HRT3/RCM). The cases with keratoconus and controls were compared with regard to KD in the anteroposterior stromal layers. Results: Of the cases with keratoconus, 15 (42.9%) were men and 20 (57.1%) were women. The mean age was 21.1 +/- 11.1 (range = 14-41) years. Of the controls, 26 (73.9%) were men and 9 (26.1%) were women. The mean age was 23.9 +/- 12.9 (range = 14-35) years. Of the 68 eyes with keratoconus, 22 (28.2%) had mild keratoconus, 23 (35.9%) had moderate keratoconus, and 23 (35.9%) had severe keratoconus. The mean anterior stromal KD was 651.4 +/- 89 cells per square millimeter in cases with keratoconus and 879.4 +/- 75 cells per square millimeter in controls (P < 0.05). The mean anterior stromal KD decreased by 25.9% in corneas with keratoconus. The mean posterior stromal KD was found to be 363.6 +/- 74 cells per square millimeter in cases with keratoconus and 469.7 +/- 56 cells per square millimeter in controls (P < 0.01). The mean posterior stromal KD decreased by 22.6% in corneas with keratoconus. The anterior stromal KD was higher than the posterior stromal KD (P < 0.001). No significant relationships were found between the stromal KD data and central corneal thickness or steepest keratometric. Conclusions: The KD in the anterior and posterior corneal stroma was decreased in patients with keratoconus, but without the use of contact lens, compared with healthy controls. This density difference was independent from the central corneal thickness and the stage of keratoconus.
Bilateral Optic Atrophy Related To Juvenile Nasopharyngeal Angiofibroma
(Taylor & Francis As, 2008) Caglar, Cagatay; Cinal, Adnan; Avcu, Serhat
Juvenile nasopharyngeal angiofibroma (JNA) is one of the most common benign nasal cavity tumors of adolescence. This tumor has the capacity to locally expand. It can cause ocular manifestations such as proptosis, decreased visual acuity, and visual field deficits. In our case, JNA caused visual loss in both eyes. Our case showed that despite the fact that the tumor is benign, it can cause serious complications, such as blindness. Therefore, early diagnosis and treatment is crucial for this type of tumor and an ophthalmologist should be most alert for symptoms of JNA.
Brucellosis and Uveitis
(Amer Soc Contemporary Medicine Surgery & Ophthalmology, 2008) Karahocagil, Mustafa Kasim; Demirok, Ahmet; Kilic, Adil; Cinal, Adnan; Caksen, Hueseyin; Yasar, Tekin
A 30-year-old-lady, (Case 1) was found to have brucella uveitis in her left eye. Serum agglutination (SAT) and SAT/Coombs titers were positive at 1:320 and 1:160, respectively. In Case 2, a 12-year-old-girl diagnosis of left brucellosis uveitis was made. Both SAT and SAT/Coombs titers were positive at 1:1280. This report confirms that Brucellae organisms as a cause of uveitis.
Causes of Visual Impairment in the Van City Area According To the Health Committee's Reports
(Turkish Ophthalmological Soc, 2012) Ceyhan, Dogan; Yasar, Tekin; Demirok, Ahmet; Cinal, Adnan; Esmer, Oktay; Batur, Muhammed
Purpose: In this study, disability reports of the Health Committee of the Hospital of the Yiiziincii Yil University School of Medicine will be evaluated. The demographic characteristics, causes and degree of visual loss, visual system impairment rating and whole body impairment rating of the people with visual impairment will be determined. Material and Method: Health committee disability reports of our hospital, between September 2006 and August 2010, were evaluated. Relevant variables of each patient were recorded and evaluated. Results: 415 health committee reports for visual impairment were found to be prepared during the period of the study. One hundred fifty three (36,9%) of the cases were female and 262 (63.1%) were male and the mean age was 41.8 +/- 22.4 years. The most frequent causes of visual impairment were macular diseases, evisceration and phitisis, amblyopia, optic nerve diseases, degenerative myopia, acquired corneal and hereditary retinal diseases. The patients who had a disability report had a mean of 41.69 +/- 25.92% visual system impairment rating and 60,76 +/- 24,67% whole body impairment rating. Discussion: This research was planned for contributing to the epidemiologic information about visual impairment in our country. This data may serve to compute the cost of visual disability reports. The information is also expected to contribute to determine the causes and measures for the prevention of diseases and conditions leading to visual disability.
Comparing Biometry in Normal Eyes of Children With Unilateral Cataract/Corneal Disease To Age-Matched Controls
(Nepal Ophthalmic Soc, 2015) Gul, Adem; Cinal, Adnan; Caglar, Cagatay; Yasar, Tekin; Kilic, Adil
Objective: To compare ocular biometry and central corneal thickness of unaffected healthy eyes of pediatric patients with monocular cataracts/corneal opacities and age-matched controls. Materials and methods: We studied 329 eyes of 329 children who were between 1 and 12 years old. The study group (n: 164) consisted of healthy fellow eyes of children operated for unilateral congenital/traumatic cataract and corneal laceration. Axial length, anterior chamber depth, lens thickness, vitreous chamber depth, and central corneal thickness were measured by ultrasound biometry/pachymetry. Results: Axial length was 22.16 mm in the study group and 21.99 mm in the control group. Anterior chamber depth, lens thickness, and vitreous chamber depth results were 3.35; 3.64 and 15.20 in the treatment group and 3.20; 3.63, and 15.15 mm in the control group, respectively. The axial length and all the components, i.e. anterior chamber depth, lens thickness, and vitreous chamber depth are higher in the unaffected healthy eyes of the pediatric patients than that of the control group but only the difference in the anterior chamber depth was statistically significant. The central corneal thickness was 548 microns and 559 microns in the study and the control groups, respectively, and the difference was found to be significant. Conclusion: Greater anterior chamber depth was chiefly responsible for the overall increase in the axial length in the study group. The central corneal thickness was significantly thinner in the study group than that of the control group.
Comparison of Argon Laser Photocoagulation-Induced Cutaneous Inflammation and Skin Pathergy Test in Behcet's Disease
(Springer, 2010) Sayarlioglu, Mehmet; Calka, Omer; Cinal, Adnan; Sayarlioglu, Hayriye; Akdeniz, Necmeddin; Topcu, Nazan; Gul, Ahmet
Nonspecific increased inflammatory response is an important feature of Behcet's disease (BD). The skin pathergy reaction (SPR) which tests this hyperreactivity in the skin is frequently used as a diagnostic tool. This study aims to investigate the argon laser photocoagulation (ALP)-induced cutaneous inflammation in BD patients and controls and also to compare the results with the skin pathergy test (SPT). The study group consisted of 35 patients with BD and 28 healthy volunteers. The ALP was applied to the left forearms of all cases from 20-cm distance (2,000 mW, 100 A mu m) with exposure times ranging from 0.2 to 0.7 s with 0.1-s increments. Also, a SPT with three prics was performed to both forearms of all cases. The ALP-induced cutaneous inflammation and SPT were evaluated and scored with the same method at 48 h, and the SPR scores of 2+ and above was accepted as positive. Positive results as defined above were found in eight cases (23%) with the ALP and in nine (26%) with the SPT in patients with BD. There was no clear correlation between the ALP and SPT results and also between the exposure time to laser beam and SPR scores. The preliminary results of this study reveal that ALP can induce a skin hyperreactivity similar to the needle prick-induced SPR in patients with BD. We, herein, showed that ALP can induce skin inflammation with its thermal effect and without any inoculation of antigen in BD. This method would help to develop another experimental method to investigate the cutaneous inflammation in BD.
Conjunctival Myxoma: a Clinicopathologic Report
(Slack inc, 2008) Kilic, Adil; Kosem, Mustafa; Demirok, Ahmet; Cinal, Adnan; Yasar, Tekin
A conjunctival myxoma was identified in a specimen obtained from a 45-year-old woman via excisional biopsy. The patient presented with a slowly growing painless epibulbar mass. The paucicellular tumor included stellate and spindle-shaped cells, mast cells, and dilated lymphatic channels embedded in a loose collagenous matrix. The differential diagnosis of conjunctival myxoma should include tumors that have myxoid patterns and richly myxoid malignant neoplasms. [Ophthalmic Surg Lasers Imaging 2008;39:514-516.]
Epidemiology of Adult Open Globe Injury
(Lippincott Williams & Wilkins, 2016) Batur, Muhammed; Seven, Erbil; Esmer, Oktay; Akaltun, Mahmut Nedim; Yasar, Tekin; Cinal, Adnan
Objective:The aim of this study was to evaluate the epidemiology and outcomes of adult open globe injuries (OGI) in the eastern part of Turkey.Methods:The retrospective study included all the patients who were diagnosed with OGI (436 eyes in 425 patients) at our clinic between 1997 and 2015. The OGI patients aged over 16 years were included into the study. Open globe injuries were classified according to the Ocular Trauma Classification. Age, gender, medical history, time between trauma and hospital admission, and mechanism of injury were recorded for each patient.Results:The incidence of OGI in adults was found to be 3.40/100,000, with 5.00/100,000 in males and 1.67/100,000 in females. Open globe injuries were mostly seen in the age group of 17 to 29 years and in October and November. The patients included 79.5% males and 20.5% females. Intraocular foreign body was detected in 99 (22.7%) eyes. A strong, linear, negative correlation was found between the Ocular Trauma Classification values and final visual LogMAR (r(p) = -0.602, P = 0.0001). The most common mechanism of injury was occupational accident (38.4%).Conclusion:Open globe injuries remain a serious public health problem, resulting in significant vision loss. Open globe injuries are mostly seen in the young, middle-aged, and male working population. Additional preventive measures should be taken for the individuals in these groups.
A Family With Congenital Cataract From Grandfather Throughout Grandchildren
(Turkish Ophthalmological Soc, 2009) Yener, Halil Ibrahim; Gul, Adem; Yasar, Tekin; Cinal, Adnan
Purpose: To report cataract cases along three generation in a large family. Introduce: Hereditary cataracts can be divided into two groups as congenital or developmental. Congenital cataracts can be seen with systemic diseases or as isolated in one third. Congenital cataract is still one of the most important treatable causes of blindness in childhood period. The proportion of blindness is 5-15/10 000 in developing countries and 1-4/10 000 in developed countries. The ratio of blindness related to cataract is 1-4/10 000 in developing versus 0,1-0,4/10 000 in developed countries. Case: A grandfather, his 10 children and five grandchildren were examined. Patients who have cataract were operated. All subjects were investigated in terms of systemic disases. Grandfather who was aphakic visited clinic for getting new glasses. Patient had operated in childhood period. He said that his two children were also operated in both eyes. We called other family members for ophthalmologic examination. We found posterior subcapsular cataract in four children and two grandchildren. None of these patients had systemic disases. conclusion: In cases of congenital or developmental cataracts, the relatives also must be examined and if needed intervention may be needed.
Intravitreal Bevacizumab for Treatment of Serous Macular Detachment in Central Retinal Vein Occlusion
(Springer, 2011) Cinal, Adnan; Ziemssen, Focke; Bartz-Schmidt, Karl U.; Gelisken, Faik
Purpose To report the long-term effect of intravitreal bevacizumab on serous macular detachment (SMD) in central retinal vein occlusion (CRVO). Methods Retrospective, interventional, noncomparative case series. Nineteen consecutive patients (19 eyes) with SMD secondary to CRVO were included. Primary outcomes were the change of the best-corrected visual acuity (BCVA) and the central foveal thickness (CFT) at final visit. Secondary outcome was the resolution of the SMD. Results The mean patient age was 65.6 years, and the mean follow-up time 21.6 months. Of the 19 eyes, 15 eyes were non-ischemic. The average number of bevacizumab injections was 5.9 from baseline to the final visit. Mean logMAR BCVA improved from 1.20 +/- 0.45 (20/317) to 0.90 +/- 0.54(20/160)P = 0.003 and mean CFT decreased from 918 +/- 280 mu m to 432 +/- 281P = 0.0001 at the final visit. The SMD resolved in 16 of the 19 eyes completely. No local or systemic complication was observed. Conclusion In this retrospective case series, a significant improvement of the vision and resolution of the SMD was found after bevacizumab treatment for CRVO with SMD. Large case series are necessary to evaluate the role of the intravitreal bevacizumab treatment for CRVO associated with SMD.
Nd:yag Laser Posterior Capsulotomy After Pediatric and Adult Cataract Surgery
(Humana Press inc, 2007) Cinal, Adnan; Demirok, Ahmet; Yasar, Tekin; Yazicioglu, Atilla; Yener, H. Ibrahim; Kilic, Adil
We evaluated neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy procedure with or without anesthesia in 35 pediatric eyes and 51 adult eyes. We concluded that Nd:YAG laser posterior capsulotomies in children are similar to adults in general aspects and that Nd:YAG laser capsulotomy can be performed safely and effectively in children under topical or no anesthesia.
Neurofibromatosis Type 1 With Subcutaneous Mass in Occipital Region, Bilateral Lisch Nodules of Iris and Cafe-Au Spots
(Modestum Ltd, 2005) Yuca, Koksal; Yilmaz, Nebi; Cinal, Adnan; Etlik, Omer; Kiris, Muzaffer
Ocular Biometry and Central Corneal Thickness in Children: a Hospital-Based Study
(Consel Brasil oftalmologia, 2014) Gul, Adem; Caglar, Cagatay; Cinal, Adnan; Yasar, Tekin; Kilic, Adil
Purpose: To investigate the distribution of axial length, anterior chamber depth, lens thickness, vitreous chamber depth, and central corneal thickness in children at different age groups. Methods: We studied 364 eyes in 182 children with ages between 1 and 12 years. Axial length, anterior chamber depth, lens thickness, and vitreous chamber depth were measured by ultrasound biometry. Central corneal thickness was measured by ultrasound pachymetry in all children. Results: The mean age was 6.54 +/- 3.42 years. The axial length was 20.95 mm in 1-2 years old and 22.95 mm in 11-12 years old. The central corneal thickness was 556 mu m in 1-2 years old and 555 mu m in 11-12 years old. The mean anterior chamber depth and vitreous chamber depth increased with age (3.06 mm to 3.44 mm in anterior chamber depth, 13.75 mm to 15.99 mm in vitreous chamber depth), and the lens thickness decreased as age increased (3.67-3.51 mm). Conclusion: The axial length increased with age and reached adult levels by the age of 9-10 years. The lens thickness gradually decreased until 12 years. The central corneal thickness measurements did not yield a linear algorithm.
The Outcomes of Lacrimal Massage or Probing Treatments at Early and Late Ages for Congenital Nasolacrimal Duct Obstruction
(Aves, 2010) Caglar, Cagatay; Batur, Muhammed; Yasar, Tekin; Cinal, Adnan
Aim: To determine the success rates of lacrimal massage and probing according to age groups for congenital nasolacrimal duct obstruction (CNDO) and emphasize the outcomes of these treatments at early and late ages. Material and Method: Between April 2000 and March 2009, two hundred and ninety-four eyes of 203 patients diagnosed with congenital nasolacrimal duct obstruction were retrospectively examined. According to symptoms and age, patients were treated with lacrimal massage and antibiotic therapy or probing and irrigation under general anesthesia. The cases were divided into two groups: Group 1 (lacrimal massage and antibiotic treatment) and Group 2 (probing and irrigation treatment). Results: In group 1, the cases were 1-42 months of age (mean 16.6 +/- 10.4 months) and were followed-up 2-32 months (mean 9.5 +/- 8.4 months). Proportions of eyes treated successfully were 53.7% overall, 96% for the 25 eyes in children 0 to 6 months old, 51.3% for the 37 eyes in children 7 to 12 months, 53.3% for the 30 eyes in children 13 to 18 months, and 39.7% for the 68 eyes in children 19 to 36 months. In group 2, the cases were 9-84 months of age (mean 24.5 +/- 13.1 months) and were followed-up 2-38 months (mean 11.1 +/- 10.6 months). Proportions of eyes treated successfully were 86.5% overall, 94.1% for the 17 eyes in children 9 to 12 months old, 93.1% for the 44 eyes in children 13 to 18 months, 93.7% for the 32 eyes in children 19 to 24 months, 84% for the 25 eyes in children 25 to 36 months, 71.4% for the 7 eyes in children 37 to 48 months, and 66.6% for the 9 eyes in children 49 to 84 months. Conclusions: In the 0-1 age group, lacrimal massage and antibiotic treatment are the first therapeutic option. Early probing before 12 months of age should be refrained from unless symptoms such as dacryocystitis or severe blepharitis are presented. We consider that delay in probing is a viable option with mild symptoms up to the age of 18 months, or later if the parents wish it. Probing is successful in the older age group and can be performed up to the age of 5 years, but the success rates decrease with increasing ages of cases. (Turk Arch Ped 2010; 45: 359-65)
Posttraumatic Oculorrhea From the Eyelid
(Lippincott Williams & Wilkins, 2018) Batur, Muhammed; Seven, Erbil; Aycan, Abdurrahman; Cinal, Adnan; Yasar, Tekin
We report a 21-month-old boy with a sutured laceration of the left upper eyelid with drainage of cerebrospinal fluid. Careful evaluation, including computerized tomography, revealed a penetrating injury of the left orbital wall and a linear bone fracture. The wound was resutured carefully. There was no cerebrospinal fluid leakage in the postoperative follow-up period.
Profile of Uveitis in Van and Surrounding Provinces (Agn, Mus, Hakkari, Igdir, Bitlis)
(Turkish Ophthalmological Soc, 2010) Gul, Adem; Kilic, Adil; Yener, Halil Ibrahim; Demirok, Ahmet; Cinal, Adnan
Purpose: The aim of this study was, by analyzing data from uveitis patients living in Van province or referred from the surrounding provinces (i.e. Agri, Mus, Hakkari, Igdir and Bitlis), to reveal the profile of uveitis in that district. Material and Method: In this study, we retrospectively investigated 855 eyes of 678 uveitis patients who were examined and followed in Yuzuncu Yil University, Ophthalmology Department between 1996 and 2008. Results: The mean age of the patients was 29.86 +/- 16.01 (range 1-79) years. 403 (59.4%) were male and 275 (40.6%) patients were female. Monocular involvement was present in 501 (73.9%), while binocular involvement was observed in 177 (26.1%) patients. According to the involved area, 395 (58.3%) patients had anterior, 85 (12.5%) intermediate, 33 (4.9%) posterior and 165 (24.3%) patients had panuveitis. No accompanying findings were detected in 406 (59.9%) patients. The most frequent accompanying disease was Behcet's disease seen in 109 (16.1%) patients. Discussion: In this study, the profile of uveitis of Van and the surrounding provinces was revealed. We think that this study is important, because it reflects the profile of uveitis of the Eastern part and together with data obtained from the other parts of Turkey, it will contribute to the development of uveitis map of the country.
Reconstruction of Lower Eyelid Defects Using a Cross Upper Eyelid Flap Composited With Ear Cartilage
(Blackwell Publishing, 2007) Atik, Bekir; Tan, Onder; Bekerecioglu, Mehmet; Cinal, Adnan; Tekes, Lutfi
Backgrounds Basal cell carcinomas (BCC) most frequently involve the lower eyelid and are treated with total excision. Various techniques have been proposed for reconstruction of the excised eyelid. Objective Because most flaps used in such techniques are bulky, thinner, and aesthetically more favorable, flaps have been sought recently. Methods Defects of the lower lid have been closed with a combination of cross-flaps and choncal cartilage prepared from the upper eyelid. Results Eleven lower lids from 10 patients operated for BCC were reconstructed. All flaps survived. The duration of follow-up was 10 months, and no complications such as relapse, ectropion, or lagophthalmus occurred. Conclusions The upper eyelid flap was found to be an appropriate cover for both the skin and the conjunctiva due to its hairless and smooth structure. The outcome in patients followed up for a mean of 10 months was successful, cosmetically and functionally.
The Risk Factors of Pterygium Development: a Hospital-Based Study
(Amer Soc Contemporary Medicine Surgery & Ophthalmology, 2008) Demirok, Ahmet; Cinal, Adnan; Yener, H. Ibrahim; Yasar, Tekin; Kilic, Adil
We evaluated the risk factors for pterygium development in Eastern Turkey. Mean protrusion value of all eyes with pterygium (all eyes in bilateral pterygium subgroups and only eyes with pterygium in unilateral pterygium subgroup, n = 130) was 16.76 +/- 2.69 mm. In all cases pterygium occurred in the eye that had greater protrusion value suggesting greater protrusion degree might be a risk factor.
Ultrasonic Elastography Evaluation in Optic Neuritis
(Taylor & Francis inc, 2018) Batur, Muhammed; Batur, Abdussamet; Cilingir, Vedat; Seven, Erbil; Cinal, Adnan; Bora, Aydin; Yasar, Tekin
Purpose: In the present study, we attempted to determine whether ultrasonic elastography (USE) evaluation can be used in a diagnosis of optic neuritis (ON). Materials and Methods: Thirteen patients who each had one normal eye and one eye with a diagnosis of ON were included in the study. Ultrasonography (US) and USE examinations were performed on the affected and non-affected eyes of all participants. Optic nerve and adjacent fat tissue regions at the same depth were selected, and USE measurements were obtained. The optic nerve diameter was measured in both normal and affected eyes. Results: The mean USE values for the optic nerve were 2.58 +/- 0.50 m/s in ON eyes and 1.91 +/- 0.39 m/s in normal eyes (p = 0.001). The mean USE values for the optic-nerve adjacent tissue were 2.26 +/- 0.45 m/s in ON eyes and 1.77 +/- 0.22 m/s in normal eyes (p = 0.001). The mean optic-nerve diameter was 3.80 +/- 1.09 mm in ON eyes and 3.28 +/- 0.98 mm in normal eyes (p = 0.005). Conclusions: USE may be considered an accessible, safe technique for the detection of significant optic-nerve tissue stiffness in ON and may be used an adjunctive tool for confirming this diagnosis.