Browsing by Author "Cinar, Vedat"

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The Acute Effects of Simulated Hypoxic Training at Different Altitudes on Oxidative Stress and Muscle Damage in Elite Long-Distance Runners
(Peerj inc, 2025) Sarikaya, Muecahit; Oge, Beyza; Embiyaoglu, Nuri Mert; Selcuk, Muzaffer; Cinar, Vedat; Oner, Salih; Batrakoulis, Alexios
Background Understanding the impact of altitude on muscle damage and oxidative stress is essential for optimizing training and recovery strategies for athletes exposed to high-altitude conditions. Therefore, this study aimed to investigate the effects of acute exercise at different altitudes on oxidative stress and muscle damage. Methods A total of twelve elite long-distance runners (mean age: 20.3 +/- 1.5 years) from different branches participated in the study. The exercise protocol was the Bruce submaximal treadmill exercise test, which was conducted under three simulated hypoxic conditions (at 1,700 m, 2,450 m, and 3,200 m) and one normoxic condition (sea level). All measurements took place at the same time of the day. After the exercise protocol, 5 ml venous blood samples were taken from the participants, while heart rate and oxygen saturation were monitored at the 3rd, 6th, 9th, and 12th minutes during the exercise. Results Significant altitude-dependent variations were observed in oxidative stress markers, with total oxidant status (TOS) (p = 0.017) and malondialdehyde (MDA) (p < 0.001) levels increasing at higher altitudes, while total antioxidant status (TAS) (p < 0.001) exhibited an elevation and oxidative stress index (OSI) (p < 0.001) demonstrated a decline as altitude increased. However, no significant difference was found in creatine kinase (CK, p = 0.059) levels. Additionally, there were significant differences in the oxygen saturation measurement taken at the 3rd (p < 0.001), 6th (p < 0.001), 9th (p < 0.001), and 12th (p < 0.001), minutes following the exercise session. There was no difference in the pulse measurement taken at the 3rd and 12th minutes, but a difference was observed at the 6th and 9th minutes post-exercise (p < 0.01). Conclusions In conclusion, the study determined that endurance exercises performed under simulated normobaric hypoxia at different altitudes increased TAS and reduced OSI in elite long-distance runners. The increase in TAS and the reduction in OSI were more pronounced at higher altitudes, particularly at 2,450 m and 3,200 m, compared to sea level. These findings highlight the need for altitude-specific training and recovery strategies to minimize oxidative stress and muscle damage in athletes.
The Effect of 6-Week Zinc Supplement and Weight Training on the Blood Lipids of the Sedentaries and Athletes
(C M B Assoc, 2018) Cinar, Vedat; Akbulut, Taner; Kilic, Yakup; Ozdal, Mustafa; Sarikaya, Mucahit
In this study, we aimed to investigate the effect of 6 weeks of zinc supplementation and weight training on blood lipids of sedentary and athletes. Research group consists of total 40 males; 20 athletes who do regularly physical exercises and 20 sedentary volunteers. The volunteers were divided into four groups. These groups were constituted in that way: the first group is a natural sedentary group which called control group as well (S); the second group is another sedentary group which is supplied with only zinc (Z+S); the third group is training group which composing of athletes and is supplied with zinc (Z+T); the fourth group is the natural training group or athletes (T). From the beginning of the study to the end of 6-weeks of training, the participants gave blood samples before and after every application order to measure the total cholesterol, LDL cholesterol and HDL cholesterol and the levels of Triglyceride. This study identifies that the values of the total cholesterol, LDL cholesterol and Triglyceride of the groups which were supplied with zinc supplement decreased, whereas the levels of HDL cholesterol increased in these groups. Consequently, this work demonstrates that the 6-weeks zinc supplement and training can make a significant contribution to the performance by changing positively the levels of blood lipid.
Strength Development, Muscle and Tissue Damage in Different Training Models
(Sciencedomain int, 2021) Akbulut, Taner; Cinar, Vedat; Oner, Salih; Erdogan, Ramazan
Purpose: The aim of this study was to determine the effects of during six weeks core and weight lifting trainings on strength development, muscle and tissue damage which may occur. Method: The research group consisted of sixteen volunteers who participated in the same age group. Participants were divided into two groups, core training group (n: 8) and weight lifting training group (n: 8). Participants continued to the program for the group to which the belonged lasted for three days a week for six weeks. Participant's performance measures (Back and leg strength, hand grip strength, vertical jump) were taken and blood samples were taken twice at rest before and at the end of the training sessions. AST, ALT, LDH, CK and CK-MB levels were determined in the blood samples taken. SPSS 22 package program was used in the analysis of the obtained data. Paired samples t test was used for intra-group comparisons. Results: When intra-group analyses are made; there were significant differences in the leg strength, vertical jump, CK and CK-MB values of the weight lifting training group, it was determined that only differences in back and leg strength values occurred in the core training group(p<0,05). Conclusion: As a result, both core and weight lifting training have led to some improvement in strength parameters. It can be said that especially weight lifting training also causes muscle damage as well as strength development.