Browsing by Author "Coskuner, I"

Now showing 1 - 2 of 2

Comparison of Propofol and Sevoflurane for Laryngeal Mask Airway Insertion
(Tohoku Univ Medical Press, 2003) Kati, I; Demirel, CB; Huseyinoglu, UA; Silay, E; Yagmur, C; Coskuner, I
In this study, we compared haemodynamic changes, laryngeal mask airway (LMA) insertion time, and complications in patients anesthetized by inhalation of sevoflurane with those of intravenous induction with propofol. One hundred patients, aged between 20-40 years were enrolled in this study. Group I received propofol (2.5 mg/kg IV) and group 2 received sevoflurane (6% + 50% N2O + 50% O-2) by inhalation using the tidal volume technique. LMA insertion time was found to be significantly longer in sevoflurane group than in propofol group. Mean arterial blood pressure was significantly lower within each group after induction in comparison to before induction values. In both groups, the LMA was successfully inserted in all patients. The quality of anaesthesia according to patients was significantly higher in the propofol group (80%) than in sevoflurane group (30%). Odor perception was significantly higher in sevoflurane group (84%) than in propofol group (38%). Apnoea was significantly higher in propofol group (40%) than in sevoflurane group (0%). Sevoflurane is an alternative to propofol for induction of anaesthesia and has a lower incidence of apnoea. Other complication rates are not higher than which propofol but the longer duration of induction time is a disadvantage. (C) 2003 Tohoku University Medical Press.
Comparison of the Effects of Desflurane and Sevoflurane on the Qtc Interval and Qt Dispersion
(Taylor & Francis Ltd, 2005) Silay, E; Kati, I; Tekin, M; Guler, N; Huseyinoglu, UA; Coskuner, I; Yagmur, C
Objective -The effects of desflurane and sevoflurane on QT interval and QT dispersion have been investigated in a prospective, double-blind, randomized study of patients undergoing noncardiac surgery. Interventions - Sixty American Society of Anaesthesiologists physical status I-II adult patients were randomly assigned to two groups. Anaesthesia was induced with inhalation of desflurane (desflurane group) or sevoflurane (sevoflurane group) in increasing concentrations to 3 minimal alveolar concentration level. The maintenance of anaesthesia was provided with 2 minimal alveolar concentration agents in both groups until the end of the study. Electrocardiogram, heart rate and blood pressure were recorded as follows: before premedication, before induction, I and 3 min after the induction of anaesthesia, after the administration of vecuronium and after the tracheal intubation. The induction times and the complications were recorded. Measurements and results -The QTc interval was significantly more prolonged with desflurane than with sevoflurane at the first and third minute after the induction, and at the third minute after the administration of vecuronium.There were no significant differences in the QT dispersion between the two groups. Heart rate and blood pressure were found to be significantly higher in the desflurane group. Conclusion -The QTc interval was more prolonged with desflurane than sevoflurane, and QT dispersion was normal with both agents.