Browsing by Author "Deǧer, Y."

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Determination of the Status of Lipid Peroxidation and Antioxidants in Cattle Infected With Dictyocaulus Viviparus
(2008) Deǧer, S.; Deǧer, Y.; Ertekin, A.; Gül, A.; Biçek, K.; Ozdal, N.
Endoparasites cause significant economic losses and health problems in domestic animals. In this study, lipid peroxidation and the antioxidant status were investigated in the lung tissue taken from twenty cattle infected with Dictyocaulus viviparus and ten healthy cattle. Malondialdehyde superoxide dismutase, catalase, glutathione, vitamin C and beta-carotene were measured. In comparison to the control group, the concentration of MDA was high (p < 0.001), but the activities of Cu-Zn-SOD and CAT, and the concentration of GSH, vitamin C and beta-carotene were low (Cu-Zn-SOD, CAT, GSH, vitamin C, p < 0.001 and beta-carotene p < 0.05) in the parasite infected group. These results suggested that endoparasitic infection is among the major causes of oxidative stress. Lipid peroxidation was observed and the activities and concentrations of antioxidants systems were decreased in the lungs of cattle infected with Dictyocaulus viviparus.
The Effect of Draxxin Treatment on Blood Gases Levels of Montofon Calves With Pneumonia
(2010) Tanritanir, P.; Raǧbeth, C.; Deǧer, Y.; Ceylan, E.
The purpose of this study was to investigate examine changes in venous blood gases of Brown Swiss calves with pneumonia. For this purpose, 30 calves exhibiting having clinical sings of pneumonia and 20 healthy calves were used. Venous blood samples were collected from the healthy and diseased calves before and after treatment with Draxxin (tulathromycin-Pfizer) in order to determine pH, pCO2, pO2, tCO2 and HCO3 levels by Blood Gas Analyzer. Compared to the controls group, in the diseased animals, there was a significant increase of pCO2 and HCO3 levels, together with a significant decrease of pH and pO2 levels (p<0.05). One week after treatment, pH, pCO2 and HCO3 levels were significantly changed. Despite this change, these levels were still similar with other groups. Also, the venous blood pO2 level went back increased to be statistically the same as the healthy animals. The tCO2 level was not found statistically different among the three groups. It is concluded that pneumonia in calves impairs gas exchange, but that gas exchange improves rapidly after treatment. © 2010 Academic Journals Inc.
Lipid Peroxidation and Antioxidant Potential of Sheep Liver Infected Naturally With Distomatosis
(2008) Deǧer, Y.; Ertekin, A.; Deǧer, S.; Mert, H.
The aim of this study was to assess the effects of natural distomatosis infections on sheep liver malondialdehyde (MDA) concentration, activities of enzymatic antioxidants (glutathione peroxidase (GPx), superoxide dismutase (Cu, Zn-SOD), catalase (CAT)) and concentrations of non-enzymatic antioxidants (reduced glutathione (GSH), vitamin C, and beta-carotene). Eighteen Akkaraman sheep naturally infected with Fasciola sp and Dicrocoelium dentriticum (D. dentriticum) and ten healthy Akkaraman sheep were included in the study Liver samples for the analysis of MDA, GPx, Cu, Zn-SOD, CAT, GSH, vitamin C, and beta-carotene and blood samples for the measurement of alanine aminotransferase and aspartate aminotransferase were collected immediately after sheep in the two groups were slaughtered. The concentration of MDA and activity of GPx in the group with distomatosis were higher than in the control group (P < 0.001). However, the Cu, Zn-SOD, CAT activities and the GSH, vitamin C concentrations in the infected group were significantly lower than in the control group (P < 0.001). The serum beta-carotene was not found to be statistically different in the two groups (P > 0.05). ALT and AST serum activities of the group with distomatosis were significantly higher in comparison to the control group (P < 0.001). In this study it was demonstrated that lipid peroxidation increased and activities or/and concentrations of antioxidant compounds were significantly changed in the liver of sheep with distomatosis.