Browsing by Author "Demir, C.Y."

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The Association of Cigarette Smoking With Septorhinoplasty Satisfaction
(Yuzuncu Yil Universitesi Tip Fakultesi, 2024) Demir, C.Y.
Introduction: It has been reported in the literature that cigarette smoking is associated with otorhinolaryngological diseases. However, literature about the connection of smoking with septorhinoplasty satisfaction is limited. Considering its negative effects on health, I hypothesized that smoking may also negatively affect septorhinoplasty satisfaction. This study aimed to investigate if smoking is associated with septorhinoplasty satisfaction. Materials and Methods: In the present study, 53 cases with septorhinoplasty were divided into two groups: smokers and non-smokers. The groups were compared for individual and clinical features and septorhinoplasty satisfaction scores. A linear correlation between septorhinoplasty satisfaction and smoking was evaluated. In the assessment of septorhinoplasty satisfaction, the Turkish vers ion of the Rhinoplasty Outcomes Evaluation Questionnaire (ROE-T) was used. Results: The findings showed that two groups in the present study were similar in age (p=0.886), weight (p=0.099), height (p=0.433), BMI (p=0.257), working status (p=0.511), education levels (p=0.064), single/married (p=1.0), urban/rural (p=1.0), postoperative duration (p=0.985), and also septorhinoplasty satisfaction (p=0.432). The satisfaction scores had no significant correlations with age (p=0.832), weight (p=0.337), height (p=0.652), BMI (p=0.696), smoking intensity (p=0.435), and smoking duration (p=0. 551) scores considering all cases with septorhinoplasty. Only, a significant positive correlation was found between septorhinoplasty satisfaction and pos toperative duration (r: 0.361; p=0.008). Conclusion: There was no significant relationship between smoking on septorhinoplasty satisfaction. However, related literature is limited and inconsistent. Therefore, the association of smoking with septorhinoplasty results is worth further investigating. © 2024, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Medico-Legal Evaluation of Keloid Formation Following Prominent Ear Correction: Malpractice or Complication
(Romanian Legal Medicine Society, 2024) Demir, C.Y.; Hekimoglu, Y.; Asirdizer, M.
Prominent ears (=prominauris=) are anatomical auricular deformities that are seen in 5% of the population, are autosomal dominant in the white population, and have psychological negative effects, especially on young girls and boys in their social environments. Various surgical intervention methods have been defined and applied for the treatment of prominent ears. After these surgical interventions, some undesirable results may occur, one of which is hypertrophic scarring and keloid formation. In the case of the 42-year-old female presented in this article, a lawsuit was filed against the physician and the hospital alleging medical malpractice after excessive keloid formation following prominent ear correction. The case was evaluated in medical and medico-legal aspects, and it was decided that the undesirable outcome was a complication, contrary to the usual legal decisions in Turkey. As a result, it was thought that the establishment of a specific insurance system for the patient before surgical interventions will not only protect the patient in the event of an undesired outcome, but also reduce unfounded malpractice claims. © 2024 Romanian Society of Legal Medicine.
A New Alternative Flap in the Closure of Meningomyelocele Defects: Modified S Flaps
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Koçak, Ö.F.; Demir, C.Y.; Ersöz, M.E.; Özsular, Y.; Sultanoğlu, Y.; Aycan, A.; Akyol, M.E.
Back defects may occur after several factors such as cancer, trauma and pressure sores. These conditions are more frequent in adult group, whereas the etiological factor in newborn infants is usually meningomyelocele defects. The aim of this study is to define more reliable and easily applicable surgical technique for the closure of meningomy elocele defects. This study included a total of 15 infants who underwent operation with the diagnosis of meningomyelocele and were treated with a modified S flap at our clinic between January 2016 and January 2017. During surgery, two flaps with a random pattern planned from the healthy skin on the right and left side of the meningomyelocele defect were transposed to close the defect. The flap donor sites were primarily sutured by elevating the surrounding skin. The left-sided flap was designed with superior pedicle and the right one with inferior pedicle. Of the participants, 13 were females and two were males with a mean age of 3.2 (min-max: 1 to 16) days. The mean follow-up was 11.5 (min-max: 5 to 17) months. The mean defect size was 6.5×5 (min-max: 5×4 to 7×6) cm. The mean flap size was 6.5×2.9 cm for the flap planned from the left side and right side of the defect. Complication was observed only in one patients including partial necrosis. Our study results suggest that modified S flap is an easily applicable flap. The greatest advantage of this flap is the shortening of the operation time. However, the major disadvantage of this flap is the random pattern flap (absence of a known blood vessel). © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
The Possible Relationship Between the Palmaris Longus and Joint Hypermobility
(Verduci Editore s.r.l, 2024) Demir, C.Y.
OBJECTIVE: The palmaris longus (PL) contributes to the palmar fascia, wrist flexion, hand muscle balance, and pinch strength. Also, PL is used as a graft source. So, PL’s presence is helpful for joint stability and grafting. On the other hand, joint hypermobility (JH) is associated with many complaints and disorders. Considering the adverse effects of JH and benefit-based evolution, the genesis rather than agenesis of PL can be expected in JH. Herein, it was hypothesized that PL might be together with JH, and individuals with PL may have higher scores of JH than those without. PATIENTS AND METHODS: Between June 2023 and October 2023, 200 participants (F/M: 1/1) were included in the study. The Schaeffer’s test and the Beighton scores were used to assess PL and JH, respectively. The participants were divided into two bilateral groups according to the presence or absence of PL. Then, the groups were compared for demographics and Beighton scores. Subgroup analyses were also done by considering gender. RESULTS: No significant differences were found between PL (+) and PL (-) groups considering females+males in age (p=0.559), gender (p=0.517), weight (p=0.375), height (p=0.061), work status (p=0.229), Beighton score (p=0.893), and JH (p=1.0). No significant differences were found between PL (+) and PL (-) groups considering females only in age (p=0.871), weight (p=0.189), height (p=0.127), work status (p=0.200), Beighton score (p=0.727), and JH (p=1.0). No significant differences were found between PL (+) and PL (-) groups considering males only in age (p=0.370), weight (p=0.981), height (p=0.400), BMI (p=0.601), work status (p=0.145), Beighton score (p=0.757), and JH (p=1.0). Conclusions: According to the results of this study, no relationship was found between PL and JH. However, this is the first study on the topic and has some limitations. © 2024 Verduci Editore s.r.l. All rights reserved.
Serum Levels of Oxidative Stress Indicators and Antioxidant Enzymes in Bell Palsy
(Medquest Communications LLC, 2018) Bozan, N.; Kocak, Ö.F.; Demir, C.Y.; Dinc, M.E.; Avc, K.; Demir, H.; Kroglu, A.F.
We conducted a prospective study to comparatively evaluate serum levels of malondialdehyde, an oxidative stress indicator, and the antioxidant enzymes glutathione, catalase, and superoxide dismutase in patients with Bell palsy. Our study population was made up of 30 patients with Bell palsy-15 men and 15 women, aged 25 to 68 years (mean: 50.4)-who were seen in the Department of Otorhinolaryngology at a tertiary care medical center. For comparison purposes, we recruited 26 healthy age- And sex-matched controls-16 men and 10 women, aged 40 to 67 years (mean: 54.3). Serum samples were obtained from all participants before the initiation of steroid treatment to the Bell palsy patients. A correlation was sought between demographic data and serum levels of malondialdehyde, glutathione, catalase, and superoxide dismutase. We found that the serum level of malondialdehyde was significantly higher in the Bell palsy group and that the levels of glutathione, catalase, and superoxide dismutase were all significantly lower (p < 0.001 for all comparisons). Correlation analysis revealed that only superoxide dismutase levels were positively correlated with age (r = 0.347, p = 0.009). We suggest that oxidative stress and antioxidant mechanisms may be involved in the pathogenesis of Bell palsy. In this context, serum levels of malondialdehyde, glutathione, catalase, and superoxide dismutase may serve as biomarkers in the diagnosis and follow-up of Bell palsy. Confirmation of the validity, reliability, and reproducibility of these findings necessitates further prospective, randomized clinical trials in larger populations. © 2018 Medquest Communications LLC. All rights reserved.
Thiol/Disulphide Homeostasis and Oxidative Stress in Patients With Peripheral Facial Paralysis
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Demir, C.Y.; Bozan, N.; Kocak, O.F.; Cokluk, E.; Sultanoglu, Y.; Ersoz, M.E.
The main pathophysiological mechanism responsible from the peripheral facial paralysis (PFP) is the ischemia, inflammation and swelling of the facial nerve. The purpose of the present study was to assess the oxidative stress parameters including the thiol/disulphide homeostasis in patients with peripheral facial paralysis. A total of 32 patients with PFP and 32 healthy controls were recruited in this cross-sectional study. Serum samples were compared for thiol/disulphide homeostasis (TDH), total oxidant status (TOS), total antioxidant capacity (TAC), paraoxonase (PON), stimulated paraoxonase (SPON), arylesterase (ARES), ceruloplasmin (CLP), myeloperoxidase (MPO), and catalase (CAT) levels. There were no significant differences between PFP patients and the control group regarding age and gender distribution. Remarkably, TOS (p=0.034), CAT (p<0.001), ARES (p<0.001), native thiol (p<0.001), total thiol (p<0.001), and native thiol/total thiol ratio (p<0.001) were significantly higher in the control group. In contrast, serum ceruloplasmin level (p=0.005) as well as disulphide/native thiol (%) (p=0.001) and disulphide/total thiol (%) (p<0.001) ratios were found to be higher in PFP patients compared to the control group. Thiol/disulphide homeostasis that was suggested as a useful indicator of oxidant/antioxidant imbalance may be a practical marker in diagnosis and follow-up of PFP. Further studies are warranted to determine the effects of nutritional and therapeutic approaches for normalization of oxidative stress in treatment and prevention of PFP. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.