Browsing by Author "Demir, Canser Yilmaz"

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Biochemical Changes Associated With Temporomandibular Disorders
(Sage Publications Ltd, 2019) Demir, Canser Yilmaz; Ersoz, Muhammet Eren
Objective To assess vitamin D, parathyroid hormone, calcitonin, calcium, phosphorus and magnesium levels in patients with versus without temporomandibular disorders (TMDs). Methods This prospective observational study included patients with TMDs and age-matched healthy controls. TMDs were diagnosed via physical and radiologic examination, and serum levels of 25 (OH) vitamin D, parathyroid hormone, calcitonin, calcium, magnesium, and phosphorus were determined. The impact of age, sex and seasonal variations in serum 25 (OH) vitamin D levels was controlled by the inclusion of age, sex and date-matched control patients. Results The study included 100 patients, comprising 50 patients with TMDs and 50 control patients. No statistically significant between-group differences were found regarding age or sex. No statistically significant between-group differences were found in terms of serum 25 (OH) vitamin D, calcitonin, calcium, magnesium or phosphorus levels. Parathyroid hormone levels were statistically significantly higher in patients with TMDs versus healthy control patients. Conclusion In patients with temporomandibular disorders, increased parathyroid hormone levels in response to vitamin D deficiency was significantly more prominent. These data suggest that, in patients with temporomandibular disorders, vitamin D deficiency should be assessed and corrected.
Comparison of Enalapril, Candesartan and Intralesional Triamcinolone in Reducing Hypertrophic Scar Development: an Experimental Study
(Springer, 2018) Demir, Canser Yilmaz; Ersoz, Muhammet Eren; Erten, Remzi; Kocak, Omer Faruk; Sultanoglu, Yilmaz; Basbugan, Yildiray
The purpose of this study was to compare the effects of oral enalapril, an angiotensin-converting enzyme inhibitor (ACE-I), oral candesartan, an angiotensin receptor blocker (ARB), and intralesional corticosteroid treatments in reducing scar formation. Twenty male rabbits were divided into five study groups: A (sham), B (control), C (ACE-I), D (ARB) and E (intralesional corticosteroid). The rabbit ear hypertrophic scar model was used. The hypertrophic scars were photographed and analyzed with the program ImageJ quantitatively to determine the degree of collagen fibers. The scar elevation index (SEI) was calculated at the end of the 40th day. Tissue samples were stained with hematoxylin and eosin and Masson's trichrome and examined under light microscopy for the determination of fibroblast number, epithelization, vascularization, inflammation and fibrosis. The SEI was the highest in the control group with the highest number of fibroblasts under the epithelium. In the steroid group, the SEI was significantly lower than both the ACE-I (p: 0.02) and ARB (p: 0.001) groups. The density of type 1 collagen fibers was the lowest in the control group, whereas type 3 collagen fibers were highest in that group. The ACE-I and ARB groups were similar regarding densities of type 1 and type 3 collagen fibers. The density of type 1 collagen fibers was the highest in the steroid group, whereas the density of type 3 collagen fibers was the lowest in that group. Enalapril, candesartan and intralesional steroid therapies were all effective in reducing scar tissue development; however, enalapril and steroid groups revealed better results. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
The Effect of the Active Ingredient Thymoquinone on Flap Viability in Random Pattern Flaps in Rats
(Springer, 2016) Kocak, Omer Faruk; Bozan, Nazim; Oksuz, Mustafa; Yuce, Serdar; Demir, Canser Yilmaz; Bulut, Gulay; Ragbetli, Murat Cetin
Thymoquinone (TQ) is a plant extract that has been shown to have antioxidant, anti-inflammatory, angiogenic, antimicrobial, and anticarcinogenic effects. The aim of this study is to research how the use of TQ affects flap viability. 42 rats were placed into 6 groups, with 7 rats in each. A 3 x 10 cm McFarlane flap model was used on the test animals. The sham group had used neither surgical nor TQ treatment. The control group had surgery but no treatment afterwards. The preoperative TQ group was given oral doses of 2 mg/kg. TQ for 10 days preoperatively with no treatment after the surgical procedure. The postoperative TQ group received oral doses of 2 mg/kg TQ for 10 days after the surgical process. The preoperative + postoperative (pre + postoperative) TQ group was given oral doses of 2 mg/kg TQ for 10 days both preoperatively and postoperatively. Finally, the dimethylsulfoxide group received 10 mg/kg dimethylsulfoxide (DMSO) for 10 days both preoperatively and postoperatively. Ten days after surgery the findings were evaluated. The average rates of necrosis were found to be 29.7 % in the control group, 19.18 % in the preoperative TQ group, 13.05 % in the postoperative TQ group, 8.42 % in the pre + postoperative TQ group, and 29.03 % in the DMSO group. The experimental groups had better area measurement, histopathological, and electron microscopic results than the control group (All; p < 0.05). We believe that, because of its antioxidant, anti-inflammatory, and angiogenic properties, thymoquinone is an agent that can prevent ischemia-reperfusion damage and, therefore, prevent necrosis.
Effect of Using the Suction Above Cuff Endotracheal Tube (Sacett) on Postoperative Respiratory Complications in Rhinoplasty: a Randomized Prospective Controlled Trial
(Dove Medical Press Ltd, 2019) Yuzkat, Nureddin; Demir, Canser Yilmaz
Background: The Suction Above Cuff Endotracheal Tube (SACETT) has a dorsal port above the cuff designed to enable the continuous or intermittent suctioning of secretions from the subglottic space. Thus, it facilitates the suctioning of excessive secretions above the cuff and around the glottis. Objectives: In this study, we investigated the effect of the using the SACETT on laryngospasm and postoperative complications in rhinoplasty operations. Methods: This randomized controlled clinical trial enrolled 132 patients undergoing rhinoplasty. The patients were randomly divided into two groups: Suction above Cuff Endotracheal Tube (n=66; Group SA) and classic endotracheal tube (n=66; Group C). Complications following general anesthesia were statistically analyzed among the two groups. Results: The incidence of postoperative laryngospasm (p=0.02) and respiratory complications was found to be lower in Group SA than in Group C. In addition, the incidence of agitation (p=0.035), postoperative nausea, and vomiting (PONV) (p=0.041), which required antiemetic drug administration, swallowing difficulty (p=0.012), and sore throat (p=0.027) were found to be lower in Group SA than in Group C. Conclusion: We suggest that using the SACETT in rhinoplasty reduces the incidence of postoperative respiratory complications as well as the incidence of agitation, sore throat, swallowing difficulty, and PONV.
Effects of Menstrual Cycle Phases on Preoperative Anxiety: a Randomized Prospective Observational Trial
(Bayrakol Medical Publisher, 2020) Yuzkat, Nureddin; Soyalp, Celaleddin; Demir, Canser Yilmaz; Kilic, Mehmetlig; Gulhas, Nurcin
Aim: Women experience physical and psychological changes as a result of their menstrual cycle. This study aimed to investigate whether the menstrual cycle had any effect on the preoperative anxiety experienced by women who were scheduled to have an operation. Material and Method: One hundred female patients who were scheduled to undergo a septorhinoplasty, and who met the inclusion criteria, were enrolled in the present study. The patients were divided into two groups according to the phase of their menstrual cycle: Group F (follicular phase) and Group L (luteal phase). The patients' anxiety level was measured preoperatively using the State-Trait Anxiety Inventory Scale. The patients' heart rate and blood pressure measurements were performed preoperatively as well as at 1 min, 5 min, and 10 min after intubation. Results: The preoperative anxiety scores of the patients in the luteal phase (41.14) were statistically significantly higher than those of the patients in the follicular phase (36.04). The blood pressure, heart rate, and peripheral oxygen saturation values were found to be similar between the two groups. Discussion: We believe that preoperative anxiety is higher during the luteal phase of the menstrual cycle than during the follicular phase, but the hemodynamic data were similar in both phases.
Effects of Normovolemic Hemodilution on Survival of Skin Flaps: an Experimental Study
(int Scientific Literature, inc, 2018) Demir, Canser Yilmaz
Background: The aim of this study was to investigate the effects of various ratios of hemodilution on the survival of McFarlane's skin flaps. Material/Methods: An experimental study was performed on 42 adult male Wistar rats (weighing 260 to 305 g) allocated to a control group without any volume loss and to 6 study groups with hemodilution ratios of 5%, 10%, 15%, 20%, 25%, and 30%. In all subjects, random-pattern McFarlane's skin flaps were uniformly elevated and re-sutured to the donor sites. The amount of necrosis was evaluated on the 7th day postoperatively and compared among the groups. Results: The amounts of flap necrosis in the groups with 5%, 10%, 15%, and 20% hemodilution ratios were significantly lower than that of the control group (p<0.001). In the 25% and 30% hemodilution groups, although there was less necrosis than in the control group, the differences were not statistically significant. Hematocrit levels, which initially decreased in conjunction with the hemodilution ratios, returned to normal levels on the 7th day after the operation. Conclusions: Our results indicated that 20% or less of the total blood volume loss that may be compensated by the normo-volemic hemodilution with dextran can improve flap survival.
Fournier Gangrene: Association of Mortality With the Complete Blood Count Parameters
(Lippincott Williams & Wilkins, 2018) Demir, Canser Yilmaz; Yuzkat, Nureddin; Ozsular, Yavuz; Kocak, Omer Faruk; Soyalp, Celaleddin; Demirkiran, Hilmi
Background: The authors studied the alterations in mean platelet volume, neutrophil-to-lymphocyte ratio, and red blood cell distribution width values together with the platelet count in hospitalized patients diagnosed with Fournier gangrene to determine their association with disease prognosis. Methods: Records of patients diagnosed with Fournier gangrene were analyzed retrospectively. Results: Seventy-four patients (49 men and 25 women) with a mean age of 57.60 +/- 15.34 years (range, 20 to 95 years) were included. Sixty-eight participants were discharged and six died during follow-up. In the discharged group, during hospitalization, there was a trend downward in neutrophil-to-lymphocyte ratio and mean platelet volume values, whereas platelet count increased significantly. In the nonsurvivor group, the neutrophil-to-lymphocyte ratio and mean platelet volume after first debridement and at the end of hospitalization were significantly higher; platelet counts at admission, after the first debridement, and at the end of hospitalization were significantly lower compared with the survivor group (p < 0.05). In correlation analysis, mortality rate was negatively correlated with platelet count at admission and after first debridement and positively correlated with the neutrophil-to-lymphocyte ratio and mean platelet volume after first debridement. Regarding the receiver operating characteristic curve analyses, a platelet count of 188,500/mu l at admission and 196,000/mu l after the first debridement, a neutrophil-to-lymphocyte ratio of 13.71, and a mean platelet volume of 9.25 fl after the first debridement were defined as the cutoff levels having the best sensitivities and specificities. Conclusions: This study suggests that platelet count at admission and platelet count, mean platelet volume, and neutrophil-to-lymphocyte ratio after first debridement and during discharge may be included among the prognostic scores of Fournier gangrene. The authors defined some threshold values that can be used during patient follow-up. Larger prospective studies are warranted to determine the exact role of those parameters in the prognosis of Fournier gangrene.
Fournier's Gangrene: Causes, Presentation and Survival of Sixty-Five Patients
(Professional Medical Publications, 2016) Taken, Kerem; Oncu, Mehmet Resit; Ergun, Muslum; Eryilmaz, Recep; Demir, Canser Yilmaz; Demir, Murat; Gunes, Mustafa
Objective: To report our experience with Fournier's Gangrene (FG) over the past eight years and evaluate the predisposing factors which affect the mortality. Methods: Sixty-five patients who were admitted to emergency surgical unit of our institution presenting with FG between January 2006 and August 2014 were included. The anatomical site of infective gangrene, predisposing factors, etiological factors, and outcomes were retrospectively reviewed. Results: Our cases included 8 women and 57 men. The average age of men was 51 +/- 13.9 (range 19-75) and the average age of women was 63 +/- 10.5 (range 52-76). Average hospitalization time was 9.2 +/- 6.6 days (range 5-25) days. The most frequent comorbid disease was diabetes mellitus and the most frequent etiology was perianal abscess. Colostomy was performed in 11 patients, orchidectomy in two patients, cystostomy in two patients. Notably, all of the 8 (12.3%) patients who died from FG had diabetes and low socioeconomic status. A total of six patients who died required more than one surgical debridement. Conclusions: Fournier's gangrene is a severe surgical emergency, with a high mortality rate. Low socioeconomic status, diabetes and more than one debridement play a major role in mortality and morbidity.
An Ideal Flap Alternative for Closure of Myelomeningocele Defects: Dorsal Intercostal Artery Perforator Flap
(Lippincott Williams & Wilkins, 2016) Kocak, Omer Faruk; Demir, Canser Yilmaz
Background:Dorsal intercostal artery perforator (DICAP) flap is an ideal flap to be used for posterior trunk defects since it leads to lower donor-site morbidity and shorter operative times, offers easy surgical planning, and uses a reliable and easily identifiable artery.Materials and Methods:The study retrospectively reviewed 52 patients with meningomyelocele defects that were closed with DICAP flap between January 2007 and May 2015.Surgical Technique:Each of the 4th to 12th posterior intercostal arteries can be used as dorsal perforators. The dominant direct cutaneous perforators derive from the 4th, 5th, 6th, 10th, and 11th posterior intercostal arteries. These perforators are located 5cm medial to the spinous processes of the thoracic vertebrae and can be easily identified.Conclusion:Dorsal intercostal artery perforator flap is a reliable flap alternative for the defects seen in neonates, including myelomeningocele, oncologic resections, burn defects, and radiation burns since it is a thin flap and offers easy surgical planning and shorter operative times.
Inferior Pedicle Reduction Mammoplasty With or Without Tourniquet: a Comparative Study
(Springer, 2017) Demir, Canser Yilmaz; Sultanoglu, Yilmaz; Kocak, Omer Faruk; Ersoz, Muhammet Eren
To compare the perioperative findings of inferior pedicle reduction mammoplasty (IPRM) performed with or without a tourniquet. This study was carried out in the plastic and reconstructive surgery department at a tertiary care center on a total of 42 consecutive women scheduled for IPRM. Patients in Group I (n = 21) underwent surgery using a tourniquet, whereas patients in Group II (n = 21) were operated on without a tourniquet. Levels of hemoglobin (Hb), hematocrit (Hct), Hct/Hb ratio, and platelet counts were noted preoperatively and on postoperative 24th and 48th h. Numbers of surgical pads and gauze sponges completely used and dripping with blood were recorded. Duration of operation, the amount of breast tissue excised on both sides, and fluid collected in hemovac drains on 48th h after operation were documented. In Group I, the operative time was significantly shorter (p < 0.001), and numbers of gauze sponges and surgical pads were fewer (p < 0.001 for both). Hemoglobin levels were significantly higher in Group I on postoperative 24th (p = 0.002) and 48th h (p = 0.007). Similarly, hematocrit levels in Group I were higher than those of Group II on postoperative 24th (p = 0.004) and 48th h (p = 0.009). We determined that use of a tourniquet significantly reduced the operative time and blood loss during IPRM. Therefore, our preliminary results support that tourniquet usage is practical and safe, and it may also improve the cost-effectiveness of the procedure.
Is There a Role for Oxidative Stress in Temporomandibular Joint Disorders
(W B Saunders Co-elsevier inc, 2018) Demir, Canser Yilmaz; Kocak, Omer Faruk; Bozan, Nazim; Ersoz, Muhammet Eren; Demir, Halit
Purpose: Data on the role of oxidative stress in temporomandibular joint (TMJ) disorders are limited. This study compared serum levels of oxidative stress indicators and antioxidant enzymes in patients with TMJ disorders. Patients and Methods: In this prospective study, patients with TMJ disorders and healthy controls were compared for descriptive characteristics (age and gender) and serum levels of malondialdehyde (MDA), an oxidative stress marker, and antioxidant enzymes catalase (CAT), glutathione (GSH), and superoxide dismutase (SOD). Results: This study included 32 patients with TMJ disorders and 32 healthy controls. There were no differences between the 2 groups for age (P =.98) and gender (P =.599). MDA levels were higher in the TMJ disorders group than in the control group (P <.001), whereas serum levels of CAT, SOD, and GSH were significantly higher in the control group (P <.001 for all comparisons). There was no correlation between age or gender and MDA, SOD, CAT, and GSH levels in the TMJ disorders or control group. Conclusion: Oxidative stress markers might have promising potential as biomarkers in the diagnostic strategy and therapeutic targets of TMJ disorders. (C) 2017 American Association of Oral and Maxillofacial Surgeons
Mean Platelet Volume, Red Cell Distribution Width, and Neutrophil-To Ratio Before and After Surgery in Patients With Carotid Body Tumors
(Lippincott Williams & Wilkins, 2017) Bozan, Nazim; Kocak, Omer Faruk; Dinc, Mehmet Emre; Demir, Canser Yilmaz; Turan, Mahfuz; Kiroglu, Ahmet Faruk
Objective: Carotid body tumors (CBTs) are rare hypervascular benign tumors that originate from the paraganglia at the carotid bifurcation. The red cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), and mean platelet volume (MPV) may serve as markers in inflammatory, cardiovascular, and neoplastic diseases. However, their prognostic value in CBTs is unknown. The purpose of this study was to assess the leukocyte count, MPV, RDW, and NLR before and after surgery in patients with CBTs. Methods: This retrospective trial included data from 80 patients with CBTs and 65 age-matched healthy controls. The leukocyte, neutrophil, lymphocyte and platelet counts, RDW, and MPV were extracted and NLR was calculated from the complete blood count results of participants. Results: The leukocyte and neutrophil counts as well as RDW levels were significantly increased in patients with CBTs compared with healthy controls (P = 0.005, P = 0.003, and P = 0.026; respectively). Patients with CBTs had lower lymphocytes counts (P = 0.241) and higher NLRs (P = 0.054); however, the difference was statistically insignificant. Moreover, no statistically significant difference was detected between groups in terms of platelet counts and MPV levels. Furthermore, the leukocyte count, platelet numbers, MPV, RDW, and NLR levels in patients with CBTs were not statistically significant after surgery (all; P> 0.05). Conclusion: This is the first study that documents the increased RDW levels and leukocyte count in patients with CBTs. The combined use of RDW and the leukocyte count along with other clinical assessments can be used as a biomarker for CBTs. Further clinical trials with larger cases series are required to determine the actual predictive roles of these systemic biomarkers.
Operative and Prognostic Parameters Associated With Elective Versus Emergency Surgery in a Retrospective Cohort of Elderly Patients
(Springer, 2019) Soyalp, Celaleddin; Yuzkat, Nureddin; Kilic, Mehmet; Akyol, Mehmet Edip; Demir, Canser Yilmaz; Gulhas, Nurcin
AimTo evaluate operative and prognostic parameters associated with elective versus emergency surgery in a retrospective cohort of elderly patients.MethodsA total of 533 geriatric patients (aged65 years, median age: 73.0 years, 50.7% were females) who underwent either elective surgery (n=285) or emergency surgery (n=248) were included in this study. Data on patient demographics, co-morbid disorders, type of surgery and anesthesia, American Society of Anesthesiologists (ASA) physical status (PS) classification, length of hospital stay, length of ICU stay, hospitalization outcome, prognosis (survivor, non-survivor) were obtained from medical records.ResultsEmergency surgery group was associated with higher prevalence of ASA-PS III (48.8 vs. 25.6%, p<0.001) and ASA-PS IV (19.0 vs. 0.4%, p<0.001) categories and higher mortality rates (20.6 vs. 4.9% vs. p<0.001) when compared to the elective surgery group. ASA-PS IV category was associated with oldest patient age (median 82.0 vs. 71.0years for ASA-PS I and II, p<0.001 for each and versus 75.0years for ASA-PS III, p<0.05) and highest mortality rate (35.4 vs. 3.4% for ASA-PS I, 6.0% for ASA-PS II and 16.5% for ASA-PS III, p<0.001) as compared with other categories.ConclusionIn conclusion, our findings in a retrospective cohort of elderly surgical patients revealed high prevalence of co-morbidities, predominance of ASA-PS II or ASA-PS III classes and an overall in-hospital mortality rate of 12.2%. Emergency as compared with elective surgery seems to be associated with older age, male gender, ASA-PS III and IV classes, higher likelihood of postoperative ICU transfer and higher mortality rates.
Prevention of Emergence Agitation With Ketamine in Rhinoplasty
(Springer, 2018) Demir, Canser Yilmaz; Yuzkat, Nureddin
Background Emergence agitation (EA), defined as restlessness, disorientation, excitation, and/or inconsolable crying, is a common phenomenon during early recovery from general anesthesia. In this study, we aimed to determine the (1) EA incidence after rhinoplasty operations in adults; (2) the effects of ketamine administered at sub-anesthetic doses just 20 min before the end of the surgery in rhinoplasty operations on agitation level, postoperative pain, side effects, and complications; and (3) to determine the risk factors for EA in adults after rhinoplasty. Materials and Methods Totally 140 patients scheduled to undergo elective rhinoplasty were enrolled in this prospective study. Patients were equally and randomly divided into two groups: saline group (control group) (n = 70) and ketamine group (n = 70). Twenty minutes before surgery completion, 1 ml saline was administered via the intravenous (i.v.) route to the saline group, while 0.5 mg/kg ketamine was administered via i.v. patients in the ketamine group. The emergence agitation level of the patients was evaluated using the Richmond Agitation-Sedation Scale just after extubation and in the post-anesthesia care unit (PACU). For postoperative pain evaluation, the Numerical Rating Scale (NRS) was scored (from 0 to 10) every 10 min until the patients were discharged from PACU. Results EA incidence in the control group was as high as 54.3%, while in the ketamine group it was 8.6% just after extubation (p < 0.001). In the PACU, EA incidence was 28.6% in the control group, while none of the patients had EA in the PACU in the ketamine group (p < 0.001). Male gender, severe pain (NRS >= 5), and smoking were defined as significant risk factors for EA both after extubation and during follow-ups in the PACU (p < 0.001). Conclusions Emergence agitation after rhinoplasty is a common complication, likely disturbing operative outcomes in adults. Ketamine at sub-anesthetic doses is highly effective in preventing EA. Further, larger-scale prospective studies are warranted to determine preventive measures for EA development in rhinoplasty.
Reply: Fournier Gangrene: Association of Mortality With the Complete Blood Count Parameters
(Lippincott Williams & Wilkins, 2019) Demir, Canser Yilmaz
Serum Levels of Heavy Metals in Patients With Bell's Palsy: a Case-Control Study
(Springer, 2024) Bozan, Nazim; Kocak, omer Faruk; Demir, Canser Yilmaz; Avci, Koray; Erdag, Omer; Turan, Mahfuz; Demir, Halit
Purpose The exact etiology of Bell's palsy (BP) remains unknown, while its potential etiopathology includes neuritis and inflammation-related demyelination as in optic neuritis. It has been reported that disruption of heavy metal homeostasis may be associated with the inflammatory process of optic neuritis; therefore, heavy metals may be involved in the pathogenesis of facial nerve neuritis. In this study, we aimed to investigate serum levels of heavy metals including essential elements [iron (Fe), zinc (Zn), copper (Cu), cobalt (Co), and manganese (Mn)], and nonessential elements [lead (Pb) and cadmium (Cd)] in patients with BP.Methods The study included 25 patients with BP and 31 healthy volunteers. For each participant, serum levels of essential and nonessential elements were measured using the atomic absorption spectrophotometer method.Results Serum levels of essential elements were significantly lower in the patient group compared to the control group (p < 0.001, for each). Serum levels of Pb increased in the patient group compared to the control group although no significant difference was achieved (p = 0.105). In contrast, serum Cd levels increased significantly in the patient group compared to the control group (p < 0.001).Conclusion Our findings suggest that decreased essential and increased nonessential elements may be associated with BP and thus, serum concentrations of these elements should be taken into account in BP. Studies are warranted to determine the role of these elements in treatment of BP.
Serum Magnesium Concentration in Patients With Bell's Palsy: a Case-Control Study
(Sage Publications inc, 2024) Demir, Canser Yilmaz; Bozan, Nazim
Introduction: Some conditions such as hyperglycemia, preeclampsia, migraine, inflammation, oxidative stress, and peripheral neuropathy are associated with magnesium deficiency and Bell's palsy. To date, however, studies have not addressed serum magnesium concentration in patients with Bell's palsy. In this article, we hypothesized that these patients may have a decreased serum magnesium concentration compared to healthy controls. Materials and Methods: In the study, a total of 24 patients with Bell's palsy and 24 healthy individuals matched were investigated. Atomic absorption spectrometry was used to determine serum magnesium concentration. The groups were then statistically compared for demographics and serum magnesium concentration. Results: No significant differences were found between Bell's palsy patients and healthy controls in age (P = .846), sex (P = 1.0), and body mass index (P = .410). However, patients with Bell's palsy had significantly lower serum magnesium levels (mu g/dL) compared to healthy controls [11.44 +/- 1.54 (8.9-15.8)] versus [27.35 +/- 2.82 (24.3-36.2); (P < .001)]. Conclusions: Our results suggest an association between decreased serum magnesium concentration and Bell's palsy. However, this is the first study on the topic and its limitations should be considered.
Serum Magnesium Levels in Patients With Deep Neck Space Abscess: a Case-Control Study
(Sage Publications inc, 2024) Demir, Canser Yilmaz; Bozan, Nazim
Objective: Deep neck space abscess (DNSA) is a serious infection associated with immune response. Magnesium has fundamental multifunctions in the body. Its insufficiency is involved in imm & uuml;ne weakness and susceptibility to infectious diseases. The present study addressed serum magnesium status in patients with DNSA. Herein, we hypothesized that patients with DNSA may have decreased serum magnesium concentration. Materials and Methods: In the study, 23 patients with DNSA and 23 matched healthy individuals were included. The atomic absorption spectrometry was used to measure serum magnesium concentration. The groups were compared statistically for demographics and serum magnesium concentration. Results: Patients with DNSA and healthy controls were statistically similar in age (p = .625), gender (p = 1.0), and smoking status (p = 1.0). However, patients with DNSA had significantly decreased serum magnesium concentration (mu g/dL) than healthy controls [25.23 +/- 4.98 (19.9-42.2) versus 31.98 +/- 5.36 (26.8-40.8)], (p < .001). Conclusion: This study demonstrated that decreased serum magnesium concentration is associated with DNSA. It is the first report on the research topic, and may inspire future studies.
Supraclavicular Dermo-Muscular Agenesis in an Infant With Gorlin-Goltz Syndrome
(Lippincott Williams & Wilkins, 2018) Demir, Canser Yilmaz; Kocak, Omer Faruk
Gorlin-Goltz syndrome (GGS) is generally characterized by the dysplasia of the skin, skeletal system, and connective tissue. In this paper, a 40-day-old baby presented with dermal and muscular agenesis on the right supraclavicular region and clinically diagnosed with GGS will be reported. To the best of the authors' knowledge, this is the first report of GGS in the literature accompanied by muscular agenesis and also this is the youngest patient diagnosed with GGS.