Browsing by Author "Demirören, K."

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Assessment of Cardiac Functions in Infants With Cow's Milk Allergy
(International Scientific Literature Inc., 2014) Ece, I.; Demirören, K.; Demir, N.; Uner, A.; Balli, S.
Background: Cow's milk allergy is the most common food allergy in children, with rates estimated at 1.9% to 4.9%. Clinical phenotypes of cow's milk allergy are varied and involve 1 or more target organs, with the main targets being the skin, respiratory system, and gastrointestinal tract. To date, no studies have investigated detailed cardiac function in children with cow's milk allergy. The current study aimed to investigate cardiac function in infants with cow's milk allergy. Material/Methods: We studied 42 infants with cow's milk allergy and 30 age- and sex-matched healthy subjects. Cardiac functions were evaluated by M-mode, pulsed-wave, and tissue Doppler echocardiography. Results: There were no significant differences in ejection fraction or mitral and tricuspid annular plane systolic excursion between the 2 groups. Pulsed-wave Doppler-derived E/A ratios in mitral and tricuspid valves were similar in both groups. Ea/Aa ratios in the left ventricle posterior wall and right ventricle free wall were lower in patients with cow's milk allergy than in the control group. The E/Ea ratio in the left ventricle, isovolumic relaxation time, deceleration time, and right and left ventricular myocardial performance indices were higher in patients in the study group. Conclusions: Our study identified reduced early diastolic tissue Doppler velocities in infants with cow's milk allergy. © Med Sci Monit, 2014.
Hyperlipidemia in Infant Case of Acute Monoblastic Leukemia
(Yuzuncu Yil Universitesi Tip Fakultesi, 2016) Ece, İ.; Dogan, M.; Akbayram, S.; Ceylan, N.; Demir, N.; Demirören, K.
Severe hyperlipidemia is a rare presentation usually associated with acute myeloid leukemia. 2-month-old girl complaining of discomfort. Her skin and conjunctivae were pale, abdominal distention and 5 cm hepatosplenomegaly were determined. Blood count revealed anemia (10 g/dL) and thrombocytopenia (41x109/L). Total leukocyte count was 24x109/L, and on blood smear, 58% blast and 42% lymphocytes were seen. Bone marrow aspirate revealed diffuse infiltration with blast cells consistent with acute monoblastic leukemia. Her plasma had a milky appearance. In the laboratory examination, triglyceride level was 1428 mg/dl, cholesterol level was 1291 mg/dl. This case report illustrate that the hematological malignancies may present with severe hypertriglyceridemia. © 2016, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Massive Gastrointestinal Bleeding Due To Vitamin K Deficiency in a Newborn
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Demir, N.; Peker, E.; Demirören, K.; Kaba, S.; Tuncer, O.
Early hemorrhagic disease of the newborn is a disease resulting from vitamin K deficiency, developing within the first 24 hours after birth. The disease may develop in babies born to mothers treated with anticonvulsants and antituberculous drugs, and sometimes as an idiopathic state despite prophylaxis with vitamin K. In this article, a case of early hemorrhagic disease in a newborn, presenting with a course of abundant gastrointestinal bleeding, has been discussed, who was born to mother with no risk factors and no history of drug use during pregnancy, with the disease onset in the first 24 hrs after birth despite administration of 1 mg vitamin K. With this article, we intended to point out that idiopathic early hemorrhagic disease may develop in newborns. © 2015, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
A Rare Cause of Jaundice in a Case: Hydatid Cyst Infestation
(Yuzuncu Yil Universitesi Tip Fakultesi, 2016) Demirören, K.; Ağengin, K.; Avcı, V.; Bilici, S.
Although the most common cause of obstructive jaundice is viral infections, there are some rare disorders which can cause this picture. We present a 15-year-old girl, admitted with an obstructive jaundice. Her laboratory tests including viral infections were normal. The diagnosis of hydatid cyst was performed with both ultrasonography and indirect hemagglutination assay. The patient was operated on and hydatid cyst was seen to be ruptured into the choledochus. In conclusion, nonviral causes of hepatitis are less common, but must be considered in the differential diagnosis. An important complication of hydatid disease is rupture to biliary tree. This situation may cause obstructive jaundice. © 2016, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
A Rare Cause of Metabolic Acidosis; Hypoplastic Left Heart Syndrome
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Demir, N.; Ece, İ.; Demirören, K.; Ceylan, N.; Peker, E.; Tuncer, O.
Metabolic acidosis is a common problem especially in newborns. Metabolic acidosis develops due to acid deposition rather than HCO3 loss in body fluids. It separates into two groups as anion gap normal and anion gap increased depending on anion gap level. Metabolic diseases, neonatal sepsis, congenital adrenal hyperplasia and congenital heart diseases should be thought with the observation of metabolic acidosis in a previously healthy infants. NaHCO3 infusion, renal replacement treatment and tamps like karbicarb, dichlora acetate, tromethamine are used for treatment of congenital heart diseases or lactic acidosis secondary to hypoxia. In this article we want to emphasize there are not only congenital metabolic illnesses under this non-response acidosis table but also there are congenital heart diseases which are in substantial rate. © 2015, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.