Browsing by Author "Demirel, CB"

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Comparison of Propofol and Sevoflurane for Laryngeal Mask Airway Insertion
(Tohoku Univ Medical Press, 2003) Kati, I; Demirel, CB; Huseyinoglu, UA; Silay, E; Yagmur, C; Coskuner, I
In this study, we compared haemodynamic changes, laryngeal mask airway (LMA) insertion time, and complications in patients anesthetized by inhalation of sevoflurane with those of intravenous induction with propofol. One hundred patients, aged between 20-40 years were enrolled in this study. Group I received propofol (2.5 mg/kg IV) and group 2 received sevoflurane (6% + 50% N2O + 50% O-2) by inhalation using the tidal volume technique. LMA insertion time was found to be significantly longer in sevoflurane group than in propofol group. Mean arterial blood pressure was significantly lower within each group after induction in comparison to before induction values. In both groups, the LMA was successfully inserted in all patients. The quality of anaesthesia according to patients was significantly higher in the propofol group (80%) than in sevoflurane group (30%). Odor perception was significantly higher in sevoflurane group (84%) than in propofol group (38%). Apnoea was significantly higher in propofol group (40%) than in sevoflurane group (0%). Sevoflurane is an alternative to propofol for induction of anaesthesia and has a lower incidence of apnoea. Other complication rates are not higher than which propofol but the longer duration of induction time is a disadvantage. (C) 2003 Tohoku University Medical Press.
The Effects of Halothane and Sevoflurane on Qt Dispersion
(Acta Cardiologica, 1999) Güler, N; Bilge, M; Eryonucu, B; Kati, I; Demirel, CB
QT dispersion is defined as the difference between QT (max) and QT (min) in the 12-lead surface EGG. It has been shown to reflect regional variations in ventricular repolarisation and is significantly greater in patients with arrhythmic events than in those without them. The aim of this study was to examine the effects of halothane and sevoflurane on QT and QTc dispersion during inhalational induction of anaesthesia. The effects on QT and QTc dispersion of halothane and sevoflurane have been investigated during induction of anaesthesia. Forty-six ASA (American Society of Anaesthesiologists) physical status I-II patients, aged 16-50 years, undergoing general anaesthesia were randomly allocated to receive either halothane or sevoflurane. The mean baseline values for QT and QTc dispersion were not significantly different between the two groups (P > 0.05). QT dispersion was increased with halothane compared with baseline values (50 +/- 16 ms vs. 29 +/- 9 ms, P < 0.01) and after sevoflurane compared with baseline (48 +/- 15 vs. 33 +/- 8 ms, P < 0.01). Also, QTc dispersion was increased with halothane compared with baseline values (48 +/- 13 ms vs. 31 +/- 9 ms, P < 0.001) and after sevoflurane compared with baseline (50 +/- 14 vs. 40 +/- 11 ms, P < 0.01). The QTc interval did not change by both sevoflurane (443 +/- 7 vs. 431 +/- 21 ms, P > 0.05) and halothane (419 +/- 33 vs. 431 +/- 19 ms, P > 0.05) compared with baseline. Both halothane and sevoflurane cause myocardial repolarisation abnormalities in man in terms of increased QTc dispersion. This may be relevant in the aetiology of arrhythmias in patients during anaesthesia with halothane or sevoflurane.
The Effects of Volatile Anesthetics on the Q-Tc Interval
(W B Saunders Co, 2001) Güler, N; Kati, I; Demirel, CB; Bilge, M; Eryonucu, B; Topal, C
Objective: To examine the effects of halothane, isoflurane, and sevoflurane on Q-Tc interval (corrected for heart rate) during inhalation induction of anesthesia. Design: Prospective, double-blind, randomized study. Setting: Departments of Cardiology and Anesthesiology in a university hospital. Participants: Patients undergoing noncardiac surgery. Interventions: A total of 65 American Society of Anesthesiologists physical status I-II patients, aged 16 to 50 years, undergoing general anesthesia, were randomly allocated to receive halothane, isoflurane, or sevoflurane. Measurements and Main Results: The time to reach the predetermined end-tidal concentrations of 3 minimum alveolar concentration was 6 to 10 minutes. When compared with preinduction values, heart rate decreased after halothane (p < 0.01) and sevoflurane (p < 0.05) administration; in contrast, heart rate increased after induction of anesthesia with isoflurane (p < 0.05). The mean QRS intervals were not significantly changed after halothane, isoflurane, or sevoflurane. The Q-Tc interval was increased with isoflurane compared with baseline (465 +/- 23 441 +/- 18 msec, p < 0.01), not changed with sevoflurane (441 +/- 17 434 +/- 19 ms, p > 0.05), and shortened with halothane (426 +/- 23 nu 445 +/- 21 msec, p < 0.01). Conclusions: Sevoflurane or halothane may be preferred to isoflurane patients with conditions that are known to induce a prolonged Q-Tc interval. The effects of Q-Tc interval changes resulting from different anesthetic agents on morbidity and the incidence of arrhythmias during anesthesia warrant further investigation. Copyright (C) 2001 by W.B. Saunders Company.
Mutism as a Complication of Total Intravenous Anesthesia by Propofol -: Reply
(Lippincott Williams & Wilkins, 2003) Kati, I; Demirel, CB; Anlar, O; Hüseyinoglu, UA; Silay, E; Elcicek, K; Elcicek, K.
An Unusual Complication of Total Intravenous Anesthesia
(Lippincott Williams & Wilkins, 2003) Kati, I; Demirel, CB; Anlar, O; Hüseyinoglu, UA; Silay, E; Elcicek, K
We report a case of mutism secondary to total IV anesthesia with propofol, as an unusual complication that we have not found in the literature. Pulse oximetry may produce skin damage after the administration of photosensitizing chemotherapeutic drugs. Surgery must often be performed in near darkness during photodynamic therapy. Limiting the duration of pulse oximetry and rotating sites allowed successful use of pulse oximetry in a long anesthetic during which verteporphin was administered.
Use of the Laryngeal Mask To Evaluate a Laryngeal Web
(Springer verlag, 1999) Çankaya, H; Kati, I; Egeli, E; Demirel, CB