Browsing by Author "Dilek, FH"

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Atypical Fibroxanthoma of the Skin and the Lower Lip in Xeroderma Pigmentosum
(Wiley, 2000) Dilek, FH; Akpolat, N; Metin, A; Ugras, S
Xeroderma pigmentosum (XP) is a rare, usually autosomal recessive disorder related to DNA repair defects. Atypical fibroxanthoma (AFX) is a pleomorphic tumour that occurs infrequently on the limbs and trunk in children, We report a child with XP who presented with AFX of the facial skin and the lower lip, The diagnosis of AFX was confirmed using histological and immunohistochemical techniques. We discuss the possibility that ultraviolet-induced damage might be implicated in the pathogenesis of AFX.
The Effect of Lymphatic Blockage on the Amount of Endotoxin in Portal Circulation, Nitric Oxide Synthesis, and the Liver in Dogs With Peritonitis
(Springer verlag, 1999) Güler, O; Ugras, S; Aydin, M; Dilek, FH; Dilek, ON; Karaayvaz, M
This study was performed to investigate the effect of lymphatic blockage on the amount of endotoxin in portal venous blood, nitric oxide synthesis, the release of aspartate aminotransferase (AST) from the liver, hepatic damage, and survival in an experimental model of dogs with peritonitis, The dogs were divided into a control group (group 1), an unligated thoracic duct peritonitis group (group 2), and a ligated thoracic duct peritonitis group (group 3), Peritoneal fluid and blood from the portal vein and femoral artery were taken for peritoneal culture, endotoxin, and AST assay, respectively, and liver biopsies were performed to assess for hepatic damage and for nitric oxide assay, There was a higher bacteria count in the peritoneal fluid from group 3 than in that from group 2 (P < 0.0001), Bacteria grew in all of the blood cultures from the group 2 animals, but growth was seen only in blood cultures from four of the group 3 animals. The levels of endotoxin, nitrite, and AST levels in group 3 were significantly increased in comparison with those in group 2 (P < 0.0001), Extensive hepatocellular necrosis,vith hemorrhage was observed in the livers of the group 3 animals, and all of them died,within 48 h, The results of this study suggest that the blockage of lymph flow has a negative effect on liver and survival in dogs with peritonitis, and that hepatic damage is directly related to the amount of endotoxin to which the liver is exposed,
Free Hydatid Cyst Only Covered With Germinative Membrane Disrupted From Fibrotic Capsule in the Peritoneal Cavity: a Case Report
(Assoc Soc Scientifique Med Belges, 1998) Arslan, H; Sakarya, ME; Bozkurt, M; Dilek, FH; Yilmaz, Y; Dilek, ON; Er, R
Echinococcosis, an endemic disease on the Asian continent, is caused by ecinococcus granulosus and rarely ecinococcus alveolaris. Although it occurs frequently in the liver and the lung, it can be localized in all tissues and organs. The purpose of this study is to report a rare localization and the complication of hydatid cyst in the pelvis : it pushed forward and upward the urine bladder and there was bilateral hydroureteronephrosis causing uraemia because of outflow obstruction. To our knowledge, a similar case has not been published before in English literature.
Multicentric Tumor of the Esophagus and Its Clinical Significance; Case Report and Review of the Literature
(Acta Medical Belgica, 2001) Dilek, FH; Yalcinkaya, I; Dilek, ON; Akpolat, N
Simultaneous occurrence of the esophageal tumor at multiple sites in a single patient is unusual. Here in, we described a patient had three separate turnoral nodules with ulceration of the esophagus. Thorax CT scan, X-ray and endoscopy revealed the only two tumoral lesion at the lower esophagus. But, the other tumoral lesion at the upper part of the esophagus was detected at operation and histopathologic examination. The aspect of treatment was changed according to this new condition during the operation. We discussed the multicentric tumoral lesions of the esophagus in view of the literature.
Protection of Intestinal Anastomoses in Septic Environment With Peritoneal Graft and Polyglycolic Acid Mesh: an Experimental Study
(Assoc Soc Scientifique Med Belges, 1996) Dilek, ON; Bakir, B; Dilek, FH; Demirel, H; Yigit, MF
We carried out an experimental study in dogs to evaluate the outcome of large bowel anastomosis with 6 stitches (Group C, n:6) in a septic environment with protection by a polyglycolic acid (PGA) mesh (Group M, n:12) or peritoneal graft (Group P, n:12). Thirty dogs were used to compare the techniques. Two dogs in each group were re-operated after 3, 5, 7, 14, 28 and 90 days. They were evaluated for adhesion formation, lumen diameter (anastomotic index), clinical features, histologic appearance and quality of healing at the anastomotic sites. All dogs in group P and group M survived, whereas 2 dogs in the control group died of anastomotic leakage and 3 dogs were re-operated for anastomotic leakage and peritonitis. In group M, one dog was reoperated because of the anastomotic leakage and two dogs were reoperated because of the anastomotic stenosis. Also, 4 anastomoses showed evidence of moderate stenosis. In group P, three anastomoses were graded as minimal stenosis. Histopathologic evaluation showed more complete epithelization, less inflammation, and less adhesion in group P than group M. We could not find any study in the literature that described and compared both techniques. We report here the results of such a study.
Relapsing Polychondritis
(Karger, 1998) Özbay, B; Dilek, FH; Yalçinkaya, I; Gencer, M
In this article, we report on a 40-year-old man with relapsing polychondritis (RP) of the tracheobronchial tree without clinical manifestations of other systems including nasal septum and earlobe cartilage involvement. The illness was diagnosed histologically, and treatment with procaine penicillin was successful. RP is an unusual systemic disorder characterized by widespread inflammation and destruction of cartilage tissues. The main cause is usually autoimmune. In RP various clinical manifestations including nasal chondritis, arthritis, scleritis, damage to tracheal and bronchial cartilage, and aortic, cardiac, and renal involvement may occur. Isolated tracheobronchial involve ment is very rare. The diagnosis must be based on a combination of clinical and pathologic features. If diagnosed early, appropriate treatment may prevent life-threatening airway obstruction.