Browsing by Author "Dundar, Ilyas"

Now showing 1 - 20 of 22

Acute Segmental Testicular Infarction Caused by Covid-19 Disease: a Case Report and Current Literature Review
(Galenos Yayincilik, 2022) Demir, Murat; Dundar, Ilyas
Coronavirus disease-2019 (COVID-19) is known to cause sepsis-associated hypercoagulopathy. Thromboembolic complications affecting many systems associated with COVID-19 disease have been described in the literature. The direct effect of this virus on male urogenital organs and possible testicular damage is still being evaluated. Follow-up studies in recovering male patients are necessary to investigate the possibility of testicular damage. In this article, we aimed to present a 30-year-old patient who presented with acute testicular pain and was diagnosed with testicular infarction due to COVID-19 with ultrasonography and contrast-enhanced magnetic resonance imaging findings.
Anterior Cerebral Artery and Anterior Communicating Artery Variations: Assessment With Magnetic Resonance Angiography
(Elsevier Science inc, 2021) Yokus, Adem; Toprak, Nursen; Gunduz, Ali Mahir; Akdeniz, Huseyin; Akdemir, Zulkuf; Dundar, Ilyas; Arslan, Harun
BACKGROUND: Although anterior cerebral artery (ACA) and anterior communicating artery (AcomA) variations have been frequently investigated by contrast enhanced angiography, the number of studies performed with magnetic resonance angiography is quite low. Our aim in this study is to investigate ACA and AcomA variations with time of flight magnetic resonance angiography (TOF MRA). METHODS: Source and maximum intensity projection images of 581 adult patients (273 males, 308 females) who were scanned for intracranial arteries with the TOF MRA method were retrospectively analyzed. RESULTS: We found the typical configuration rate of the ACA and AcomA complex to be 40.6%. The most common structural anatomic variations out of typical configuration were AcomA aplasia (18.9%) and AcomA hypoplasia (17.9%), respectively. The least frequent variation that we found was duplicated AcomA (0.9%). When we examined gender comparatively, unilateral A1 segment aplasia was found to be higher in males and azygos ACA was found to be higher in females (P = 0.001 and P = 0.029, respectively). CONCLUSIONS: In this study, in which we used the TOF MRA technique, we detected high rates of anatomic variations of ACA and AcomA. This method, which is noninvasive, does not require contrast material and does not contain ionizing radiation, can be preferred especially in the evaluation of patients with kidney disease and contrast allergy.
Clinical Impacts of Juxtapapillary Duodenal Diverticulum Detected on Computed Tomography
(Bentham Science Publ Ltd, 2022) Dundar, Ilyas; Goya, Cemil; Hattapoglu, Salih; Ozkacmaz, Sercan; Ozgokce, Mesut; Turkoglu, Saim; Turko, Ensar
Background: Diverticula are commonly observed in the duodenum. Duodenal Diverticulum (DD) usually does not give symptoms throughout life and is diagnosed by coincidence. However, it may present with different symptoms in patients. Objective: This study aims to evaluate the prevalence of DD and Juxtapapillary Duodenal Diverticilium (JDD) and its association with other possible pathologies and to determine its clinical impact by using Computed Tomography (CT). Methods: This retrospective observational study, which was taken consecutively between the years of 2013-2020, was evaluated in the Radiology Department. The total number of cases was 4850 (male-2440; female-2410). CT images were evaluated by two experienced radiologists at the workstation. DD and JDD prevalence and clinical findings in the hospital registry system were examined. Results: The age of the patients included in the study ranged from 17 to 92 years (mean age 46.94 +/- 16.42). In patients with DD (female-130; male-101), mean age was 62.24 +/- 12.69 (21-92). The prevalence of DD was 4.76% (n=231). The prevalence of JDD was 4.02% (n=195) and increased with age (p<0.01). The average diameter of the JDD was measured as 23.29 +/- 8.22 (9.5-55.3) mm. A significant positive correlation was found between age and DD diameter (p=0.039). DDs were found most commonly 84.42% (n=195) in the second segment of the duodenum as JDD. In patients with JDD, the mean diameter of choledochus and wirsung canal were 6.7 +/- 2.4 (3-15.3) mm and 0.31 +/- 0.1 (0.1-6.5) mm respectively. The choledochal diameter was correlated with the JDD size (p - 0.004). Cholelithiasis (n 56), choledocholithiasis (n 20), cholecystitis (n=52), diverticulitis (n=15), duodenitis (n=37), pancreatitis (n=5) and hiatal hernia (n=60) with JDD were observed. Periampullary carcinoma was detected in one patient. Conclusion: Our study shows that cholelithiasis, choledocholithiasis, cholecystitis, diverticulitis, duodenitis, pancreatitis may be associated with JDD. Therefore, in contrast-enhanced abdominal CT scans taken for various reasons, investigation of the presence and characteristics of JDD and detection of pathologies that may be associated with JDD are important for patients to benefit from early diagnosis and treatment opportunities and to take precautions against possible complications.
Comparison of Computed Tomography Findings Between Adult and Pediatric Covid-19 Patients
(Bentham Science Publ Ltd, 2024) Dadali, Yeliz; Ozkacmaz, Sercan; Unlu, Erdal; Ozkacmaz, Ayse; Alparslan, Muhammed; Dundar, Ilyas; Goya, Cemil
Purpose: This study aims to compare chest computed tomography (CT) findings between adult and pediatric patients with coronavirus disease-19 (COVID-19) pneumonia. Materials and Methods: This study included 30 pediatric patients aged 1 to 17 years and 30 adult patients over 18 years of age with COVID-19 pneumonia confirmed by reverse transcriptase-polymerase chain reaction (RT-PCR) who have findings related to COVID-19 on Chest Computed Tomography. The CT findings of adult and pediatric patients were compared with a z-test. Results: Bilateral involvement (p:0.00056), involvement in all five lobes (p<0.00001), and central and peripheral involvement (p:0.01928) were significantly higher in the adult group compared to the pediatric group. In the pediatric group, the frequency of unilateral involvement (p:0.00056), involvement of solitary lobe (p:0.00132), and peripheral involvement (p: 0.01928) were significantly higher than in the adult group. The most common parenchymal finding in adults and pediatric patients was ground-glass opacities (100% and 83%, respectively). Among the parenchymal findings in adults, ground-glass opacities with consolidation (63%) were the second most common finding, followed by air bronchogram (60%) in adults, while in pediatric patients, halo sign (27%) and nodule (27%) were the second most common, followed by the ground-glass opacities with consolidation (23%). Conclusion: The CT findings of pediatric COVID-19 patients must be well-known as the course of the disease is usually less severe, and the radiological findings are uncertain when compared with adults.
Comparison of Medical Treatment Efficiency With Shear Wave Elastography Values of Thrombus in Patients With Lower Extremity Deep Vein Thrombosis
(Lippincott Williams & Wilkins, 2023) Ince, Suat; Ozgokce, Mesut; Ozkacmaz, Sercan; Dundar, Ilyas; Turko, Ensar; Ayyildiz, Veysel A.; Goya, Cemil
In lower-extremity deep vein thrombosis (DVT), thrombus age is essential for successful treatment. The aim of our study was to compare the shear wave elastography (SWE) values measured before treatment and achieved lumen patency after treatment in lower-extremity DVT patients with total occlusion. Patients diagnosed with DVT in the acute-subacute stage (<4 week) with total thrombosis in lower extremity were included in this prospective study. Shear wave elastography measurements were performed where the thrombus was most prominent and homogeneous. To evaluate patient response to treatment, lumen patency (partial [>25%] or total recanalization) was examined using color Doppler imaging in the first and third months posttreatment. Shear wave elastography values with and without patency were compared using an independent t test. Among 75 patients in this study, at the first-month color Doppler imaging examination, the SWE values were 1.77 +/- 0.49 (1.09-3.03) m/s in patients who achieved lumen patency (n = 42) and 2.21 +/- 0.54 (1.24-3.36) m/s in those who did not show lumen patency (n = 33). The difference between the groups' mean elastography value was statistically significant (P < 0.001). At the third-month examination, the SWE values were 1.76 +/- 0.46 (1.09-3.03) m/s in patients with lumen patency (n = 55) and 2.52 +/- 0.48 (1.74-3.36) in patients without lumen patency (n = 20). The difference between the 2 groups' mean elastography value was statistically significant (P < 0.001). We concluded that it is more difficult to achieve lumen patency in veins occluded by thrombus with higher elasto values, and endovascular interventional procedures should be considered during the initial treatment of high SWE value thrombosis.
Deep Learning in Distinguishing Pulmonary Nodules as Benign and Malignant
(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2024) Akinci, Muhammed Bilal; Ozgokce, Mesut; Canayaz, Murat; Durmaz, Fatma; Ozkacmaz, Sercan; Dundar, Ilyas; Goya, Cemil
Background: Due to the high mortality of lung cancer, the aim was to find convolutional neural network models that can distinguish benign and malignant cases with high accuracy, which can help in early diagnosis with diagnostic imaging. Methods: Patients who underwent tomography in our clinic and who were found to have lung nodules were retrospectively screened between January 2015 and December 2020. The patients were divided into two groups: benign (n=68; 38 males, 30 females; mean age: 59 +/- 12.2 years; range, 27 to 81 years) and malignant (n=29; 19 males, 10 females; mean age: 65 +/- 10.4 years; range, 43 to 88 years). In addition, a control group (n=67; 38 males, 29 females; mean age: 56.9 +/- 14.1 years; range, 26 to 81 years) consisting of healthy patients with no pathology in their sections was formed. Deep neural networks were trained with 80% of the three-class dataset we created and tested with 20% of the data. After the training of deep neural networks, feature extraction was done for these networks. The features extracted from the dataset were classified by machine learning algorithms. Performance results were obtained using confusion matrix analysis. Results: After training deep neural networks, the highest accuracy rate of 80% was achieved with the AlexNET model among the models used. In the second stage results, obtained after feature extraction and using the classifier, the highest accuracy rate was achieved with the support vector machine classifier in the VGG19 model with 93.5%. In addition, increases in accuracy were noted in all models with the use of the support vector machine classifier. Conclusion: Differentiation of benign and malignant lung nodules using deep learning models and feature extraction will provide important advantages for early diagnosis in radiology practice. The results obtained in our study support this view.
Does Contrast-Enhanced Computed Tomography Raise Awareness in the Diagnosis of the Invisible Side of Celiac Disease in Adults
(Springer, 2022) Goya, Cemil; Dundar, Ilyas; Ozgokce, Mesut; Turko, Ensar; Ozkacmaz, Sercan; Durmaz, Fatma; Hattapoglu, Salih
Purpose This study aimed to evaluate the diagnosis and determine major and minor criteria of celiac disease (CD) with the malabsorption patterns (MABP) in the small intestine and colon on computed tomography (CT) and additional CT findings. Methods This retrospective study was conducted with 116 patients diagnosed with CD, 14 CD patients recovering with treatment, and 35 control patients with non-CD. All patients had CT examinations and histopathological diagnoses. The sensitivity, specificity, PPV, NPV, and accuracy values of each CT finding defined in the literature were statistically evaluated. According to the patient and control groups, the numerical values of the findings and the sensitivity and specificity values were measured according to this cut-off value. The distribution of CT findings according to pathological Marsh data was evaluated in CD patients. Results Sensitivity and specificity were found to be higher in small bowel MABP findings, mesenteric hypervascularity, and increased SMV/aorta diameter. There was a numerically significant difference in MDCT findings between the control and pathological Marsh groups. In the ROC analysis performed in terms of the total numerical values of each MDCT finding observed between the groups, it was found that there were more than 7 MDCT findings, 100% sensitivity, and 92% specificity. The presence of four major and three minor criteria or three major and four minor criteria were considered significant. Conclusions Being aware of CT findings below the iceberg that may suggest CD in abdominal CT examinations performed in patients with atypical clinical and malabsorption findings or other nonspecific findings may prevent diagnostic delay and unnecessary procedures. [GRAPHICS] .
Efficacy of Shear Wave Elastography in Malignity Assessment of Thyroid Nodules With Atypia of Undetermined Significance and Comparison With Ti-Rads
(Bayrakol Medical Publisher, 2022) Durmaz, Fatma; Ozgokce, Mesut; Ozkacmaz, Sercan; Dundar, Ilyas; Alay, Murat; Goya, Cemil; Kotan, Mehmet Cetin
Aim: The aim of this study is to investigate the effectiveness of shear wave elastography (SWE) in the differentiation of benign-malignant thyroid nodules diagnosed with atypia of undetermined significance (AUS) and to compare with the American College of Radiology (ACR)-thyroid imaging reporting and data system (TIRADS). Material and Methods: This monocentric study comprised 52 patients (9 males; 43 females) who were diagnosed with AUS by thyroid FNAB. All patients included in the study had gray scale ultrasound (US) and SWE images. The mean SWE value was calculated for each nodule, and TIRADS scores were determined based on the US. The obtained data were compared based on the histopathological result in patients who had undergone surgical treatment, and based on the cytology result in patients followed-up by FNAB, for the differentiation of benign and malignant nodules. Results: Nineteen patients were found to have malignant nodules and 33 had benign nodules. The mean SWE was 2.89 +/- 0.51 (2.30-3.92) and 2.91 +/- 0.48 (2.16- 3.79) in the malignant and benign cases, respectively. The results of independent T-tests between the two groups were insignificant (p=0.89). TIRADS 2-3 (total 29 patients) nodules were considered possibly benign, and TIRADS 4-5 (total 23 patients) possibly malign, the sensitivity, specificity, positive predictive and negative predictive value of TIRADS were identified 100%, 87.9%, 82.6% and 100%, respectively, when compared with the pathology results. Discussion: There was no significant difference in SWE values in the differentiation of malignant-benign thyroid nodules with AUS. However, the ACR-TIRADS criteria still maintain their importance.
The Efficiency of Acoustic Radiation Force Impulse (Arfi) Elastography in the Differentiation of Renal Cell Carcinoma and Oncocytoma
(Bentham Science Publ Ltd, 2024) Ozgokce, Mesut; Dundar, Ilyas; Durmaz, Fatma; Ozkacmaz, Sercan; Kankilic, Nazim A.; Aslan, Rahmi; Akinci, M. Bilal
Purpose This study is to investigate the effectiveness of Acoustic Radiation Force Impulse (ARFI) elastography in differentiating radiologically similar renal cell carcinoma (RCC) and oncocytoma in solid masses of the kidney. Methods The patients with solid renal mass histopathological diagnosed after excision or tru-cat biopsy who underwent a preoperative ARFI elastography of the lesion during a 4-year period were included in this study. Preoperative shear wave velocity (SWV) values were measured in all the lesions. SWV results of RCCs and oncocytomas were compared by an independent t-test, and cut-off, sensitivity and specificity values were calculated. Results Forty-two of the 60 patients included in the study were men (70%) and, 18 were women (30%), and the mean age was 59.7 +/- 14 (27-94) years. Among 46 RCCs (76.6%), 23 and 14 oncocytomas, 5 (23.4%) were located in the right kidney (p:0.34722). Mean SWV values were found to be significantly higher in RCCs (2.87 +/- 0.74 (0.96-4.14) m/s) than oncocytomas (1.83 +/- 0.78 (0.80-3.76) m/s) (p <0.001). In the ROC analysis, a cut-off value of 2.29 m/s was found to havean 80.4% sensitivity and a 78.6% specificity for the discrimination of RCCs from oncocytomas. Conclusion ARFI elastography measurements may be useful in distinguishing RCC and oncocytomas that may have similar solid radiological imaging features.
The Efficiency of Diffusion-Weighted Magnetic Resonance Imaging in the Differentiation of Malign and Benign Cavitary Lung Lesions
(Lippincott Williams & Wilkins, 2023) Durmaz, Fatma; Ozgokce, Mesut; Aydin, Yener; Yildiz, Hanifi; Ozkacmaz, Sercan; Dundar, Ilyas; Goya, Cemil
Purpose:The present study investigates the diagnostic efficiency of apparent diffusion coefficient (ADC) values in differentiating between malignant and benign cavitary lesions on diffusion-weighted magnetic resonance imaging (DWI). Materials and Methods:This prospective study included 45 consecutive patients identified with a cavitary lung lesion with a wall thickness of >= 5 mm on thoracic computed tomography in our clinic between 2020 and 2022, and who underwent thoracic DWI within 1 week of their original computed tomography. ADC measurements were made on DWI by drawing a region of interest manually from the cavity wall, away from the lung parenchyma in the axial section where the lesion was best demonstrated. The patients were then classified into benign and malignant groups based on the pathology or clinico-radiologic follow-up. Results:The sample included 29 (64.4%) male and 16 (35.6%) female patients, with a mean age of 59.06 +/- 17.3 years. Included in the study were 1 patient with 3 and 3 patients with 2 cavitary lesions each, with a total for the sample of 50 cavitary lesions. There were 23 (46%) malignant and 27 (54%) benign cavitary lung lesions. The mean ADC value (x10(-3) mm(2)/s) of the malignant and benign cavitary lesions was 0.977 +/- 0.522 (0.511 to 2.872) and 1.383 +/- 0.370 (0.930 to 2.213), respectively. The findings were statistically significant using an independent samples t test (P=0.002). The mean wall thickness of the malignant and benign lesions was 12.47 +/- 5.51 mm (5 to 25 mm) and 10.11 +/- 4.65 mm (5 to 22 mm), respectively. Although malignant cavities had a higher mean wall thickness than benign cavities, the difference was statistically insignificant (P=0.104). Conclusion:A significant difference was identified between the ADC values measured in DWI of the malignant and benign cavitary lung lesions. DWI, a noninvasive and rapid imaging method, can provide useful information for the differential diagnosis of cavitary lesions and can minimize unnecessary biopsies.
Efficiency of Diffusion-Weighted Mri for Differentiating Radiologically Similar Simple and Type I Hydatid Cysts of the Liver
(Sage Publications Ltd, 2022) Dundar, Ilyas; Ozgokce, Mesut; Durmaz, Fatma; Ozkacmaz, Sercan; Turkoglu, Saim; Goya, Cemil
Background Determining the nature of purely cystic hepatic lesions is essential because different kinds have different follow-ups, treatment options, and complications. Purpose To explore the potential of apparent diffusion coefficient (ADC) values of diffusion-weighted imaging (DWI) for the differentiation of type I hydatid cysts (HC) and simple liver cysts (SLC), which have similar radiological appearances. Material and Methods This single-center prospective study was conducted during 2016-2019. Round, homogenous, anechoic liver cysts >1 cm were classified according to at least two years of imaging follow-up, radiological features, serology, as well as puncture aspiration injection reaspiration procedure and pathology results. ADC values of 95 cysts (50 type I HCs and 45 SLCs) were calculated on DWI. The differences in ADC values were analyzed by independent t-test. Results Of 51 patients, 28 were female, 23 were male (mean age 32.07 +/- 22.95 years; age range 5-82 years). Mean diameter of 45 SLCs was 2.59 +/- 1.23 cm (range 1.2-7.6 cm) and ADC(mean) value was 3.03 +/- 0.47 (range 2.64-5.85) while mean diameter of 50 type I HCs was 7.49 +/- 2.95 cm (range 2.8-14 cm) and ADC(mean) value was 2.99 +/- 0.29 (range 2.36-3.83). There was no statistically significant difference in ADC values between type I HCs and SLCs Conclusion Some studies report that ADC values of type I HCs are statistically significantly lower than those of SLCs. Others suggest no significant difference. In our study with a higher number of cases, using ADC parameters similar to those in previous studies, we did not find any statistically significant difference.
Evaluation of Celiac Disease With Uniphasic and Multiphasic Dynamic Mdct Imaging
(Springer, 2021) Goya, Cemil; Dundar, Ilyas; Ozgokce, Mesut; Turkoglu, Saim; Turko, Ensar; Ozkacmaz, Sercan; Almali, Necat
Purpose An analysis of dynamic contrast MRI has been shown to provide valuable information about disease activity in Crohn's disease and Celiac disease (CD). However, there are no reports of dynamic multi-detector computer tomography use in patients with CD. The aim of this study is to determine and compare the perfusion dynamics of the patients treated with control subjects and the perfusion dynamics in patients with untreated CD, using dynamic contrast in MDCT and compare studying contrast dynamics in Marsh types as well. Methods In this retrospective study, uniphasic and multiphasic MDCT, untreated, treated, incompatible CD patients and healthy control group duodenum wall thickness and HU values were compared in terms of patient groups and modified Marsh types. Result In dynamic CT, the highest contrast curve was observed in the untreated group and Marsh type 1. While the contrast curve of the untreated and non-compliant patients increased rapidly and showed wash out, the type 4 contrast curve was observed, whereas the treated and control group slowly increased type 5 contrast curve. In the contrast-enhanced CT in the venous phase, in the ROC analysis between Marsh 1-2 and Marsh 3a-c, the sensitivity was 97% and the specificity was 87% when the cut off was taken as 4.45 mm for wall thickness (p: 0.005). Conclusion Contrast-enhanced single-phase and dynamic MDCT imaging in CD patients may be useful in evaluating the inflammatory and pathological process in the small intestine. [GRAPHICS] .
Genotyping of Echinococcus Granulosus Human Isolates Obtained From the Puncture, Aspiration, Injection, and Re-Aspiration (Pair) Process in Türkiye
(Iranian Scientific Society Medical Entomology, 2023) Akkas, Onder; Ozgokce, Mesut; Aydemir, Selahattin; Dundar, Ilyas; Ekici, Abdurrahman
Background: Echinococcus granulosus is spread by the excretion of cystic organs into the environment. The dog is infected via eating the cystic organ. It then contaminates the environment with eggs of E. granulosus, which are infective to humans and animals. We aimed to determine the E. granulosus genotypes that cause infection in humans in the Van region, Turkiye.Methods: Sixty patients between 18 and 100 years of age, who underwent the puncture, aspiration, injection, re-aspiration (PAIR) procedure in the Department of Radiodiognastics of Van Yuzuncu Yil University, Van, Turkiye were included in the study. PAIR fluids were examined microscopically and DNA was isolated from the fluids. After DNA isolation, polymerase chain reaction (PCR) was performed using primers that amplify the E. granulosus NADH dehydrogenase subunit 1 (NAD1) gene region. After sequence analysis of the PCR amplicons, Basic Local Alignment Search Tool (BLAST) was performed.Results: In the microscopic examination, protoscolex or hook was detected in 42 (70%) of the samples. DNA was successfully extracted from all of the cyst fluids containing protoscolex and hook, and the NAD1 gene region was PCR-amplified. After using BLAST, all of the samples were determined to be an E. granulosus sensu stricto G1 genotype. Sequence comparison revealed that four (9.5%) isolate sequences showed single nucleotide polymorphism (SNP). Sequences of isolates with SNP submitted to the GenBank with accession numbers OR565864 to OR565867.Conclusion: E. granulosus s.s. G1 genotype, known as sheep strain, is common in human hydatid disease in the Van region of Turkiye.
Hidradenitis Suppurativa Accompanying Crohn's Disease With Multifocal Abscess
(2016) Arslan, Harun; Batur, Abdussamet; Alpaslan, Muhammed; Dundar, Ilyas; Durmaz, Fatma
Multifokal absesi olan yaşlı bir hastada Crohn hastalığı ve hidradenitis süpürativa birlikteliği sunmayı amaçladık. 81yaşındakadınhastaöksürük,kilokaybı,kasık bölgesinde kötü kokulu cerahat akıntısı ve çok sayıda ağrılışişlik şikayetleri ile başvurdu. Bilgisayarlıtomografide tüm gastrointestinal sistemde, subkutanöz alanda, mediastinal-hiler ve axiller bölgelerde multifokal abse odakları saptandı. Subkutanöz abse odağından alınan biyopsi sonucu hidradenitis süpürativa, kolonoskopide intestinal traktan alınan biyopsi sonucu Crohn hastalığıolarak geldi. Crohn hastalığı ve hidradenitis süpürativa birlikteliğinin farkındaolmakveyetersiztedaviyiönlemekiçingastrointestinalsisteminiyiaraştırılmasıbüyükönemtaşımaktadır.
Proposal for an Index for Predicting the Success of Sleeve Gastrectomy: a Pilot Study
(Mary Ann Liebert, inc, 2019) Celik, Sebahattin; Sumer, Aziz; Yavuz, Alpaslan; Zarbaliyev, Elbrus; Dundar, Ilyas
Background: Determining the relationship between remnant gastric volume (RGV) following laparoscopic sleeve gastrectomy (LSG) and the percentage of excess weight loss (%EWL) remains a challenge. The components of RGV appear to play a much more important role than total RGV. We aimed to determine whether there is an optimal ratio between the components of RGV with respect to %EWL and to develop a statistical model to predict %EWL. Materials and Methods: This was a multicentric prospective observational cross-sectional study conducted between 2014 and 2016 with a minimum of 2 years of follow-up. Two university-affiliated hospitals participated in this study. Patients who underwent LSG as treatment for obesity were enrolled in the study. Those who did not consent to postoperative computed tomography (CT) or whose postoperative CT images were not technically suitable for calculating volumes were excluded. Patients whose follow-up was incomplete were also excluded. Out of a total of 82 patients, 63 completed follow-ups and met the inclusion criteria. By dividing RGV into its components (the antrum and body parts), volumetric measurements were made using a novel CT-based software program. RGV was divided by the antrum volume to yield a ratio that we termed the "Sleeve Coefficient" (SC). Taking SC as an independent variable, nonlinear regression analysis was performed to determine the best model for curve estimation of %EWL. The radiologists who measured the RGV components were blinded to the outcomes. Results: The participants were primarily female (56F/7M), with a mean age of 35.9 (+/- 11.9) and a mean preoperative body mass index of 44.8 (+/- 7.4). The best fitted model for predicting %EWL in the second year was the cubic model. In the second year following LSG, the mean %EWL was 76.1% (+/- 18.2%). There was no significant correlation between total remnant volume and %EWL. Optimal %EWL was obtained when the mean SC was 3.3 +/- 1.5 (95% CI: 2.94-3.72). Conclusions: The ratio between RGV and antral (rather than total remaining stomach) volume appears to be of greater importance and utility in predicting %EWL and in managing LSG candidates. The proposed SC should be validated by further studies.
Radiological Evaluation of Response To Treatment in Hepatobiliary Fascioliasis
(Elsevier Espana Slu, 2022) Goya, Cemil; Ozkacmaz, Sercan; Ozgokce, Mesut; Turko, Ensar; Dundar, Ilyas; Durmaz, Fatma
Purpose: In this study, we aimed to evaluate the computed tomography (CT) findings of Fasciola hepatica infestations on initial and follow-up imagings after treatment, and also to describe the role of CT during diagnosis. Methods: In this retrospective study, patients with a diagnosis of fascioliasis by clinical and laboratory examination who underwent initial and follow-up contrast-enhanced abdominal CT scans after treatment (a single oral dose of 10 mg/kg Triclabendazole) were included. The CT scans were evaluated regarding liver and spleen sizes, portal and splenic vein diameters, involved hepatic segment numbers and involvement patterns, the presence of focal perihepatic hyperdensity, gallbladder wall thickening, dilatation of the intrahepatic biliary tract, periportalright subdiaphragmatic lymphadenopathy, hepatic subcapsular and intra-abdominal bleeding, and perihepatic/intraabdominal free fluid. Initial (pre-treatment) and post-treatment CT scans (average 25 months after the treatment) were compared with for these features. Results: A total of 36 patients with a mean age of 39.28 +/- 14.64 [15-83] years, were included in this study. After treatment, marked improvement in liver parenchymal involvement, biliary and hepatic subcapsular hematoma were detected and focal perihepatic hyperdensity, free intraperitoneal fluid disappeared. Conclusion: Contrast-enhanced abdominal CT can be used in the diagnosis and posttreatment follow-up of fascioliasis. Awareness of intrahepatic/extrahepatic lesions and all the complications of fascioliasis can greatly aid the diagnosis and also evaluation of the response to treatment. (C) 2021 Elsevier Espana, S.L.U. All rights reserved.
Radiological Evidence of Testicular Damage in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Sonoelastography's Potential Role
(Lippincott Williams & Wilkins, 2023) Dundar, Ilyas; Ozkacmaz, Sercan; Demir, Murat; Ozgokce, Mesut; Durmaz, Fatma; Ozkacmaz, Ayse; Goya, Cemil
This preliminary study aimed to evaluate the possible damage to the male reproductive system that the severe acute respiratory syndrome coronavirus 2 virus causes by quantitatively measuring and comparing the tissue stiffness of the testis and epididymis with acoustic radiation force impulse sonoelastography in patients who have COVID-19 with a healthy control group. This prospective study was conducted between February and July 2021 with 65 cases. We used sonoelastography to evaluate male patients 18 years or older, who had applied to the urology clinic with nontesticular complaints, and were found to not have any underlying testicular pathology after a clinical-laboratory evaluation. The clinical-laboratory imaging findings and reverse transcription-polymerase chain reaction test results of all patients diagnosed with COVID-19 were reviewed from the hospital database. We measured the shear wave velocity values of the epididymis and the testes of 31 proven severe acute respiratory syndrome coronavirus 2 patients and 34 healthy subjects and compared them with an independent t test. For the patient and control group subjects, the mean age was 37.55 & PLUSMN; 13.08 (23-71) and 40.5 & PLUSMN; 16.25 (18-81) years, respectively. The mean shear wave velocity values of the left-right and bilateral testes and epididymis of the patient group were statistically substantially higher (P < 0.05) than in the control group. In the receiver operating characteristic analysis, when the cutoff values for the bilateral testes and epididymis were determined as 1.39 and 1.64 m/s, respectively, the AUC was 77% to 73.4%, the sensitivity was 87% to 74%, and the specificity was 65% to 62%. Our findings show that testicular and epididymal tissue stiffness increased in patients with COVID-19. We recommend adding sonoelastography to urogenital examinations of male reproductive system in patients who are recovering from COVID-19.
Renal Alveolar Echinococcosis Mimicking Renal Neoplasm With Brain Metastasis
(Springer india, 2021) Dundar, Ilyas; Ozgokce, Mesut; Durmaz, Fatma; Demir, Feyza
Alveolar echinococcosis is a rare parasitic disease that is endemic to the northern hemisphere in many parts of the world. Humans are coincidental intermediate hosts infected after eating contaminated food, including fruits and vegetables or being in contact with foxes or dogs. Although most alveolar echinococcal infections are localized to the liver, the larvae may spread to other organs by regional extension or distant metastasis along hematogenous or lymphatic pathways. The liver and lungs are the most commonly affected organs. Alveolar echinococcosis involving the kidneys is very rare. Parasitic infection causes granulomatous response on the host immune system. These lesions may be misdiagnosed as malignant neoplasms. Imaging modalities such as MRI provide useful diagnostic information for the accurate diagnosis of alveolar echinococcosis. In this case, we aimed to present radiological imaging and pathological findings of alveolar echinococcosis mimicking renal cell carcinoma of the right kidney with brain metastasis in a 40-year-old male patient with right lumbar pain.
The Role of Computed Tomography Hounsfield Unit Values in the Differentiation of Benign and Malignant Cavitary Lung Lesions Computed Tomography Hu Values in the Differentiation of Cavitary Lung Lesions
(Bayrakol Medical Publisher, 2021) Dundar, Ilyas; Ozgokce, Mesut; Durmaz, Fatma; Ayyildiz, Veysel Atilla; Yildiz, Hanifi; Turko, Ensar; Goya, Cemil
Aim: This study aims to investigate the rote of Hounsfield unit (HU) values measured by contrast-enhanced computed tomography (CT) in the differentiation of benign and malignant cavitary lesions (CLs), which are frequently encountered in the lung parenchyma. Material and Methods: In this retrospective descriptive study approved by the relevant ethics committee, thoracic CT records taken for various reasons between 2019 and 2021 were scanned from the hospital database. According to the demographic characteristics and histopathological results, the patients were divided into benign and malignant groups. The HU values of 24 patients with CLs were measured by CT and the averages were calculated. HU values were compared by independent t-test. Results: Of the 24 patients, 20 were mate (83.3%) and 4 were female (16.7%), and the mean age was 59.98 +/- 16.65 (22-78) years. There were a total of 34 cavitary lung lesions in these 24 patients, including 18 benign (52.94%) and 16 malignant (47.06%) lesions. The mean age of 13 patients (54.17%) with benign etiology was 51.62 +/- 18.79 (22-78) and the mean size of all benign lesions was 30.05 +/- 9.51 (16-53) mm. The mean age of the 11 patients (45.83%) with malignant etiology was 68.55 +/- 6.56 (57-78) and the mean size of all malignant lesions was 39.25 +/- 23.45 (13-95) mm. The mean HU values of the 18 benign and 16 malignant CLs were 32.11 +/- 12.25 (15-60) and 63.88 +/- 24.5 (15-109), respectively, representing a statistically significant difference (p=0.001). In receiver operating characteristic curve analysis, the area under the curve was 86.8%, and when the cut-off was determined as 41.5, the sensitivity was 87.5% and the specificity was 88.9%. Discussion: We think that HU density values measured from the CL wall by contrast-enhanced CT may be useful in the differentiation of frequently detected benign and malignant CLs, which have similar radiological imaging findings.
Three-Dimensional Computed Tomographic Examination of Pelvic Cavity in Van Cats and Its Morphometric Investigation
(Wiley, 2020) Yilmaz, Osman; Soyguder, Zafer; Yavuz, Alpaslan; Dundar, Ilyas
This study was carried out to determine the morphometric values of the pelvic cavity, the cranial and caudal pelvic aperture by three-dimensional (3D) reconstruction of the images obtained by computed tomography in adult Van Cats and to show the differences between these indicators in both genders. A total of 16 adult Van Cats, eight male and eight female, were used in the study. Animals were anesthetized with ketamine-xylazine combination and were scanned by computerized tomography. Images of the pelvic cavity were obtained. Three-dimensional reconstruction of the pelvis was performed with three-dimensional modelling program. Measurements of the diameters of the pelvic cavity, the cranial and caudal pelvic aperture were calculated from these images, and statistical analyzes were performed. Three-dimensional modelling of the pelvic cavity of Van Cats were examined between males and females. The results showed that there were significant (p < .05) differences between measurement of the pelvic inclination, the medial transverse diameter, the caudal transverse diameter and the angle between ischiatic arch. In addition, the correlations between age and weight were found statistically significant (p < .05) with the dorsal transverse diameter, the intermediate transverse diameter and the caudal transverse diameter in males. On the other hand, the correlations of age were statistically significant (p < .01) with the cranial pelvic aperture and the caudal pelvic aperture in females. In conclusion, some biometric values of pelvic cavity were observed to be statistically different in Van Cats.