Browsing by Author "Duz, R."

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Effects of Lowered Dialysate Sodium on Left Ventricle Function and Brain Natriuretic Peptide in Maintenance of Hemodialysis Patients
(Sage Publications Ltd, 2017) Akyol, A.; Akdag, S.; Asker, M.; Gumrukcuoglu, H. A.; Duz, R.; Demirel, K. C.; Begenik, H.
Introduction: Impaired diastolic flow is characterized by decreased left ventricular (LV) filling diastole, abnormal LV distensibility, or delayed relaxation. B-Type natriuretic peptide (BNP) is an indicator of various cardiovascular diseases and body volume status. The aim of this study was to determine whether the lowering of dialysate sodium (Na) levels is effective on LV systolic and diastolic parameters and BNP in the maintenance of hemodialysis patients. Materials and Methods: The study included 49 chronic hemodialysis patients. Left atrium (LA) diameter and LV ejection fraction, LV systolic and diastolic diameter, deceleration time (DT), pulmonary artery pressure (PAP), inferior vena cava diameter (IVCD), early diastolic transmitral flow (E) and late diastolic transmitral flow (A) velocities, E/A ratio, isovolumic relaxation time, peak early diastolic velocity (E), late diastolic velocity (A) of tissue Doppler mitral annulus, and flow propagation velocity of mitral inflow (V-p) were measured before and 6 months after hemodialysis with low Na dialysate. Results: Six months after low Na hemodialysis, a decrease was observed in echocardiographic parameters such as PAP and IVCD (p < 0.05, p < 0.001, and p < 0.001, respectively). However, a significant difference was not observed in LA diameter. In LV diastolic measurement of E and A waves, E/A ratio, DT, V-p, septal E and A, and lateral E and A exhibited significant improvement by low Na HD. BNP level was significantly reduced (p < 0.001). Conclusions: Lowered dialysate Na concentration improves PAP, IVCD, and LV diastolic properties assessed by mitral inflow filling, tissue Doppler velocity, and mitral inflow velocity propagation.
Evaluation of Cardiology Consultations During the Covid-19 Pandemic Period
(Yuzuncu Yil Universitesi Tip Fakultesi, 2021) Babat, N.; Duz, R.; Karaduman, M.; Tuncer, M.
In this study, we scientifically examined the consultations of the patients being hospitalized from the other departments to the cardiology department during Coronavirus Disease 2019 (COVID-19) pandemia. Consultations to the cardiology department between 01 April-31 May 2020 and 01 April-31 May 2019 were discussed. Demographic characteristics and reasons of consultations were compared. A different approach was f ollowed in COVID-19 patients diagnosed with compared to patients in other clinics. The rate of consulted patients in 2019 year was 14.4% (866/5989). Its rate in 2020 year was found as 18.5% (462/2486) (p: <0.001). A statistically significant difference was obtained in both groups. The use of drugs prolonging the Qt, preoperative and increase in cardiac enzymes were found statistically significant in terms of the consultations (p: <0.001-<0.001-0.003-0.016, respectively). Face to face interviews were made in 29% (33/114) of the patients who were consulted from COVİD-19 clinics. In 71% (81/114) patients, electrocardiography (ECG) s were evaluated digitally. In this study, although there was a decrease in the number of hospitalized patients during the COVİD-19 pandemia, we observed an increase in the number of patients being consulted to cardiology clinic. The relationship between COVİD-19 disease and cardiovascular diseases and drugs being used in the treatment increased the workload of the cardiology clinic during the pandemic period. © 2021, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Platelet-To Ratio May Predict the Severity of Calcific Aortic Stenosis
(International Scientific Literature Inc., 2015) Akdag, S.; Akyol, A.; Asker, M.; Duz, R.; Gumrukcuoglu, H.A.
Background: Platelet-to-lymphocyte ratio (PLR) is an emerging inflammatory indicator which is closely associated with adverse cardiovascular events. Therefore, we aimed to investigate the relationship between PLR and the severity of calcific aortic stenosis (AS). Material/Methods: The study was designed as a retrospective study. A total of 86 consecutive patients with calcific AS were divided into two groups as mild-to-moderate AS and severe AS according to the transaortic mean pressure gradient. PLR levels were calculated from the complete blood count (CBC). Results: Platelet to lymphocyte ratio was significantly higher in severe and mild-to-moderate AS groups when compared to the control subjects (151±31.2, p<0.001, 138±28.8 vs. 126±26.5, p=0.008, respectively). In the subgroup analysis of AS patients, PLR was found to be higher in the severe AS group compared to mild-to-moderate group (p<0.001). A significant correlation was found between PLR and transaortic mean pressure gradient in patients with AS (r=0.421, p<0.001). Conclusions: Our study results demonstrated that increased PLR correlates with the severity of calcific AS. © Med Sci Monit, 2015.
Post Covid-19 Evaluation of Patients With Cardiac Complaints by Using Echocardiography
(Yuzuncu Yil Universitesi Tip Fakultesi, 2024) Duz, R.; Çoldur, R.; Babat, N.
The aim of the study was to evaluate the presenting complaint, cardiovascular sequelae prevalence and type and demographic characteristics of patients who had no previous disease and had cardiac complaints after COVID-19, and to show the presence of cardiac sequelae objectively by evaluating every patient without chronic diseases by echocardiography and electrocardiography. In this study, we evaluated symptomatic patients by using echocardiography. In this study, there were included patients who recovered from COVID-19 disease and presented to the cardiology outpatient clinics. These patients were divided into two groups: those presenting within the first 30 days after recovery and those presenting between 30 and 60 days after recovery. Thirty patients who had not had COVID-19 before, who applied to the cardiology outpatient clinics, were selected as the control group. The rate of dizziness, palpitations, chest pain and blood pressure dysregulation did not differ si gnificantly between group I(patients presenting within 30 days after recovery), group II(patients presenting between 30 and 60 days after recovery), and group III(control group) (p> 0.05). Dyspnea rate in group I was significantly higher than group II and group III. There was a difference between groups in left ventricular ejection fraction. In group III, sPAP ≥ 35 mmHg ratio was significantly lower than group I and group II (p <0.05). sPAP ≥ 35 mmHg ratio did not differ significantly (p> 0.05) between group I and group II. While dyspnea was an important complaint in the first periods, it decreased over time. In addition, it was observed that right ventricular functions and left ventricular diastolic functions improved over time. It is noteworthy that there are more patients with pericardial effusion compared to the control group, which shows us that the inflammation process is continuing. © 2024, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.