Browsing by Author "Ece, İ."

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Hyperlipidemia in Infant Case of Acute Monoblastic Leukemia
(Yuzuncu Yil Universitesi Tip Fakultesi, 2016) Ece, İ.; Dogan, M.; Akbayram, S.; Ceylan, N.; Demir, N.; Demirören, K.
Severe hyperlipidemia is a rare presentation usually associated with acute myeloid leukemia. 2-month-old girl complaining of discomfort. Her skin and conjunctivae were pale, abdominal distention and 5 cm hepatosplenomegaly were determined. Blood count revealed anemia (10 g/dL) and thrombocytopenia (41x109/L). Total leukocyte count was 24x109/L, and on blood smear, 58% blast and 42% lymphocytes were seen. Bone marrow aspirate revealed diffuse infiltration with blast cells consistent with acute monoblastic leukemia. Her plasma had a milky appearance. In the laboratory examination, triglyceride level was 1428 mg/dl, cholesterol level was 1291 mg/dl. This case report illustrate that the hematological malignancies may present with severe hypertriglyceridemia. © 2016, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Impact of Patent Ductus Arteriosus and Subsequent Therapy With Ibuprofen on the Release of S-100b and Oxidative Stress Index in Preterm Infants
(International Scientific Literature Inc., 2014) Demir, N.; Ece, İ.; Peker, E.; Kaba, S.; Ustyol, L.; Balahoroğlu, R.; Tuncer, O.
Background: Hemodynamically significant patent ductus arteriosus (hsPDA) leads to injury in tissues/organs by reducing perfusion of organs and causing oxidative stress. The purpose of this study was to evaluate the oxidant/antioxidant status in preterm infants with hsPDA by measuring the total antioxidant capacity and total oxidant status and to assess neuronal damage due to oxidant stress related to hsPDA.; Material/Methods: This prospective study included 37 low-birth-weight infants with echocardiographically diagnosed hsPDA treated with oral ibuprofen and a control group of 40 infants without PDA. Blood samples were taken from all infants, and than the total antioxidant capacity (TAC), total oxidant status (TOS), and S-100B protein levels were assessed and oxidative stress index was calculated before and after therapy.; Results: The mean pre-therapy TOS level and oxidative stress index (OSI) value of the patients with hsPDA were significantly higher, but TAC level was lower than in the control group. There were no statistically significant differences in the mean post-therapy values of TOS, TAC, OSI, and S-100B protein between the two groups.; Conclusions: hsPDA may cause cellular injury by increasing oxidative stress and damaging tissue perfusion; however the brain can compensate for oxidative stress and impaired tissue perfusion through well-developed autoregulation systems to decrease tissue injury. © Med Sci Monit 2014.
A Late Diagnosis of Vein of Galen Aneurysm in Newborn
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Demir, N.; Ece, İ.; Batur, A.; Peker, E.; Tuncer, O.
A Rare Cause of Metabolic Acidosis; Hypoplastic Left Heart Syndrome
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Demir, N.; Ece, İ.; Demirören, K.; Ceylan, N.; Peker, E.; Tuncer, O.
Metabolic acidosis is a common problem especially in newborns. Metabolic acidosis develops due to acid deposition rather than HCO3 loss in body fluids. It separates into two groups as anion gap normal and anion gap increased depending on anion gap level. Metabolic diseases, neonatal sepsis, congenital adrenal hyperplasia and congenital heart diseases should be thought with the observation of metabolic acidosis in a previously healthy infants. NaHCO3 infusion, renal replacement treatment and tamps like karbicarb, dichlora acetate, tromethamine are used for treatment of congenital heart diseases or lactic acidosis secondary to hypoxia. In this article we want to emphasize there are not only congenital metabolic illnesses under this non-response acidosis table but also there are congenital heart diseases which are in substantial rate. © 2015, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.