Browsing by Author "Ece, I."

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Assessment of Cardiac Functions in Fetuses of Gestational Diabetic Mothers
(Mary Ann Liebert Inc., 2015) Balli, S.; Pac, F.A.; Ece, I.; Oflaz, M.B.; Kibar, A.E.; Kandemir, O.
Assessment of Cardiac Functions in Infants With Cow's Milk Allergy
(International Scientific Literature Inc., 2014) Ece, I.; Demirören, K.; Demir, N.; Uner, A.; Balli, S.
Background: Cow's milk allergy is the most common food allergy in children, with rates estimated at 1.9% to 4.9%. Clinical phenotypes of cow's milk allergy are varied and involve 1 or more target organs, with the main targets being the skin, respiratory system, and gastrointestinal tract. To date, no studies have investigated detailed cardiac function in children with cow's milk allergy. The current study aimed to investigate cardiac function in infants with cow's milk allergy. Material/Methods: We studied 42 infants with cow's milk allergy and 30 age- and sex-matched healthy subjects. Cardiac functions were evaluated by M-mode, pulsed-wave, and tissue Doppler echocardiography. Results: There were no significant differences in ejection fraction or mitral and tricuspid annular plane systolic excursion between the 2 groups. Pulsed-wave Doppler-derived E/A ratios in mitral and tricuspid valves were similar in both groups. Ea/Aa ratios in the left ventricle posterior wall and right ventricle free wall were lower in patients with cow's milk allergy than in the control group. The E/Ea ratio in the left ventricle, isovolumic relaxation time, deceleration time, and right and left ventricular myocardial performance indices were higher in patients in the study group. Conclusions: Our study identified reduced early diastolic tissue Doppler velocities in infants with cow's milk allergy. © Med Sci Monit, 2014.
Effects of Carvedilol Therapy on Cardiac Autonomic Control, Qt Dispersion, and Ventricular Arrhythmias in Children With Dilated Cardiomyopathy
(International Scientific Literature Inc., 2013) Oflaz, M.B.; Balli, S.; Kibar, A.E.; Ece, I.; Akdeniz, C.; Tuzcu, V.
Background: The purpose of this study was to examine the effects of carvedilol therapy on autonomic control of the heart and QT-interval dispersion (QTd) among children with idiopathic dilated cardiomyopathy (DCM) whose symptoms were not adequately controlled with standard congestive heart failure therapy. Material/Methods: Patients with DCM who were treated with carvedilol were enrolled in the study. All patients had undergone carvedilol therapy in addition to standard therapy for at least 6 months. Clinical, echocardiographic, and electrocardiographic parameters, and 24-h Holter records of patients were retrospectively evaluated before and after carvedilol treatment. Results: A total 34 patients (mean age: 7.4±4.3 years) with DCM were analyzed in the study. The median follow-up period was 9.5 months. After the 6 months of carvedilol therapy the clinical score significantly improved, left ventricular ejection fraction (LVEF) and fractional shortening (LVFS) significantly increased, and left ventricle enddiastolic dimensions and end-systolic dimensions significantly decreased. There were statistically significant increases in mean SDNN, SDANN, rMSSD, and pNN50 (p=0.002, p=0.001, p=0.008, and p=0.026, respectively). After the carvedilol therapy, SDNN was correlated with the clinical score, heart rate, LVEF, LVFS, and total premature ventricular contractions (PVCs). In addition, rMSSD and pNN50 were correlated with heart rate, LVEF and LVFS. A significant reduction was observed in QTc-minimum, QTc-maximum, and QTd values (434.9±40.7 vs. 416.1±36.5, 497.8±43.6 vs. 456.3±41.7, 58.6±17.1 vs. 49.3±15.6; p<0.001, p=0.001, and p=0.008, respectively). QTd was significantly related to PVCs (r=0.62, p=0.02). Conclusions: We conclude that the addition of carvedilol to standard therapy can improve clinical symptoms and heart rate variability, and reduce in arrhythmia markers in children with DCM. © Med Sci Moni.
Efficacy and Safety of Rectal Ibuprofen for Ductus Arteriosus Closure in Very Low Birth Weight Infants
(Springer, 2016) Demir, N.; Peker, E.; Ece, I.; Balahoroglu, R.; Tuncer, O.
Is Kawasaki Disease a Side Effect of Vaccination as Well
(OMICS Publishing Group, 2014) Ece, I.; Akbayram, S.; Demiroren, K.; Uner, A.
Different subtypes of vasculitis have been reported after vaccination in adults. However, only one case of Kawasaki disease in an infant after hepatitis B vaccination has been described. We report a case of Kawasaki disease in a 2 month-old infant who developed the Kawasaki disease 1 day after receiving his first dose of diphtheria tetanus-acellular pertussis, Haemophilus b and pneumococcal conjugate vaccine. © 2014 Ece I et al.
A Male Newborn With Simpson-Golabi Syndrome, Presenting With Metopic Synostosis, Anal Atresia, and Total Anomalous Pulmonary Venous Return
(Medecine Et Hygiene, 2014) Demir, N.; Peker, E.; Ece, I.; Kaba, S.; Dogan, M.; Tuncer, O.
A male newborn with Simpson-Golabi-Behmel syndrome, presenting with metopic synostosis, anal atresia, and total anomalous pulmonary venous return: Simpson-Golabi-Behmel syndrome is a clinical condition described by Simpson, characterized with multiple congenital anomalies and caused by Glypican 3 (GPC3) mutations of the X-linked gene. Typical findings such as overgrowth, hypoplastic changes of hands and feet, visceromegaly, cleft palate and macrocephalic distinctive facial features and multiple organ anomalies might be observed. GPC3 mutation is claimed to generally cause metopic synostosis. This case was reported because even though a lot of anomalies accompanying Simpson-Golabi-Behmel syndrome had been noticed, combination of metopic synostosis, has not been reported before.