Browsing by Author "Ege, Bilal"

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Ankaferd Kanama Durdurucunun Donör Bölgede Yara İyileşmesi Üzerine Etkisinin İncelenmesi
(2023) Altındal, Dicle; Çalışır, Metin; Talmaç, Ahmet Cemil; Ege, Bilal
Amaç: Bu çalışmanın amacı, serbest dişeti grefti (SDG) cerrahisi sonrası palatinal donör alanda Ankaferd Kanama Durdurucu (AKD) kullanımının etkisini değerlendirmektir. Gereç ve Yöntemler: Toplam 12 hasta (24 palatal bölge) çalışmaya dahil edildi. Her hastada donör bölgeler rasgele iki gruba ayrıldı. Test grubuna AKD+kollajen ped uygulandı. Kontrol grubuna ise sadece kollajen ped uygulandı. Kanama, tam epitelizasyon, duyarlılık, ağrı skoru, alınan analjezik sayısı, yara boyutu, Landry, Turnbull ve Howley (LTH) indeksi ve doku kalınlığı (DK) açısından donör sahalar değerlendirildi. Bulgular: İntraoperatif kanama bakımından kontrol grubunda anlamlı şekilde daha fazla hastada (n=9) kanama gözlenirken; test grubunda hiçbir hastada kanama gözlenmedi (p=0.000). Test grubunda 14. günde daha yüksek tam epitelizasyon varlığı (33.3%) tespit edilmesine rağmen, epitelizasyon bakımından gruplar arasında anlamlı bir farklılık tespit edilmedi. Gruplar arasında ağrı skorları, analjezik kullanımı, yara boyutu, LTH indeksi ve DK bakımından anlamlı bir farklılık tespit edilmedi. Zamanlar arasındaki değişim miktarı incelendiğinde sadece 21. gün ile 6. hafta arasındaki DK’daki değişim, istatistiksel olarak anlamlı bulundu (p=0,028). Sonuç: Çalışmamızda SDG cerrahisi sonrasında AKD kullanımının intraoperatif kanama, kısa dönem tam epitelizasyon ve uzun dönem DK’da olumlu etkisinin olduğu ancak erken dönem yara iyileşmesi, postoperatif ağrı ve analjezik tüketimi konusunda tek başına kollajen süngere üstünlük sağlayamadığı söylenebilir.
The Effect of Ozone Gas on Il-1β and Il-10 Levels of Gingival Crevicular Fluid in Aggressive Periodontitis Patients
(Taylor & Francis inc, 2019) Calisir, Metin; Talmac, Ahmet Cemil; Ege, Bilal; Poyraz, Omer; Dumlupinar, Ebru
Although the use of ozone therapy in dentistry has become widespread, the number of controlled clinical trials evaluating its effectiveness in periodontal therapy is limited. The aim of this study was to evaluate the efficacy of ozone treatment, that is used in concert with scaling and root planning (SRP), on clinical periodontal parameters and to analyze its effect on cytokine levels of GCF in aggressive periodontitis patients. Totally, 27 patients with aggressive periodontitis were randomly selected into groups of treatment with either subgingival SRP followed by application of ozone with a periodontal probe (SRP+ozone) or subgingival SRP followed by irrigation with serum irrigation (SRP-control). The following parameters were evaluated at baseline (T0), and 6 weeks (T1): plaque index (PI); gingival index (GI); probing pocket depth (PPD), clinical attachment loss (CAL), GCF volume, GCF Interleukin-1 beta (IL-1 beta), and GCF Interleukin-10 (IL-10) cytokine levels. There was a significant difference in terms of clinical periodontal parameters before and after treatment in both groups. When comparing between groups, there was no significant difference between the treatment methods after 6 weeks with respect to the PI, PPD, CAL, and GCF IL-10 levels. In contrast, GI, GCF volume, and GCF IL-1 beta levels were statistically significantly different between the two groups at the 6th week after treatment. Application of ozone as an adjunctive therapy to SRP was shown to provide a statistically significant improvement in treatment results compared to SRP plus serum irrigation.
Effect of Submucosal Dexamethasone on Postoperative Pain, Swelling and Trismus After Periodontal Surgery: a Randomized Clinical Study
(Springer Heidelberg, 2024) Altindal, Dicle; Alsafadi, Anas; Alshujaa, Basem; Talmac, Ahmet Cemil; Ege, Bilal; Calisir, Metin; Alpaslan, Nazli Zeynep
Objective The aim of this study is to evaluate the effectiveness of submucosal 8 mg (2 mL) dexamethasone (DEX) on postoperative pain, swelling, chewing efficiency, trismus, healing, and discomfort after periodontal flap surgery (PFS). Methods In this randomized controlled split-mouth study, 25 patients underwent PFS in the mandible, whereby postoperative, submucosal DEX was injected to the surgical field to the test group and submucosal normal saline was applied to the control group. Pain was evaluated using the Visual Analogue Scale (VAS) and the 101-point numeric rate scale in the first 8 h after PFS and on the 2nd, 3rd, 4th, and 7th days, whereas swelling, chewing efficiency, trismus, healing, discomfort and analgesic consumption were evaluated preoperatively on the 1st, 2nd and 7th days. Results In the intergroup evaluation, the VAS-7th hour value of the test group was lower than the control group(p < 0.05). On the 1st day, it was observed that there was less swelling and more chewing efficiency in the test group than in the control group(p < 0.05). When time-dependent changes were examined, the decrease in mouth opening due to trismus in the control group was greater than that in the test group on the 1st and the 2nd days compared to the preoperative period(p < 0.05). Finally, postoperative healing, discomfort, and analgesic consumption were similar between groups. Conclusion Within the limits of this study, the submucosal DEX may be an effective protocol in the management of pain, swelling, and trismus after PFS. Clinical relevance Our findings shed light on the possible effects of DEX after PFS. Trial registration This study was registered on ClinicalTrials.gov (NCT06119893).