Browsing by Author "Egeli, E"

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Effects of Topical Mitomycin on Inner Ear
(Tohoku Univ Medical Press, 2002) Çankaya, H; Egeli, E; Kuntsal, L; Ozbek, H; Icli, M
QANKAYA, H., EGELI, E., KUNTSAL, L., OZBEK, H. and ICLI, M. Effects of Topical Mitomycin on Inner Ear: A Light and Electron Microscopic Study. Tohoku J. Exp. Med., 2002, 197 (2), 81-86 - Providing maintenance of myringotomy patency without use of ventilation tubes in the treatment of secretory otitis media has been one of the important study areas. For this reason, laser and Mitomycin C (MMC) are used together in experimental studies. But there has been no ultrastructural studies concerning whether leakage of MMC to middle ear during application of this procedure has an ototoxic effect or not and if so, to what extent. In this study, we searched the ultrastructural changes which occurred in the middle ear by direct applications of MMC to the middle ear for different time durations. The study was carried out over thirty adult guinea pigs without ear diseases. Bilateral myringotomy was performed and MMC was applied only to the right middle ear of each guinea pig. The first group received MMC once for 10 minutes, the second group received it once for 20 minutes, and the third group took it each day for 10 minutes during a one week period. The left ears of the samples were accepted as the control group. On the 8th day, sacrification was carried out. After electron and light microscopy examination, significant changes in the inner ear were observed in the third group though no significant change was observed for the first and the second groups. As a result it was concluded that the application of MMC to the middle ear once for a short duration causes no toxic effect on the inner ear. - mitomycin; secretory otitis media; myringotomy; ototoxicity; inner ear. (C) 2002 Tohoku University Medical Press.
Hearing Loss Caused by Lightning Strike: Case Report and Review of the Literature
(B C decker inc, 2002) Cankaya, H; Egeli, E; Evliyaoglu, Z
Is Aspiration Necessary Before Tympanostomy Tube Insertion
(Lippincott Williams & Wilkins, 1998) Egeli, E; Kiris, M
Aspiration of middle ear fluid after myringotomy is performed routinely, although investigators imply a cause-and-effect relationship between suction noise and acoustic trauma. This prospective randomized study investigated if aspiration was necessary. Fifty-one myringotomies and 50 tympanostomy tube insertions were performed on 27 patients. A suction instrument was utilized in 24 ears and was not used in 27 ears. In a follow-up period, no difference was observed between the two groups. The authors did not establish that aspiration is indeed harmful, but tympanostomy tube insertion can be performed without suctioning middle ear effusion.
Laryngeal Amyloidosis -: a Rare Cause of Laryngocele
(Elsevier Science inc, 2002) Çankaya, H; Egeli, E; Ünal, Ö; Kiris, M
Laryngocele may be defined as an abnormal dilatation of the saccule of the ventricle and its pathogenesis is uncertain. We report a laryngocele caused by amyloidosis localized to larynx in a 60-year-old male patient. We would like to mention that amyloidosis should be evaluated in the etiology of patients diagnosed as having a laryngocele. (C) 2002 Elsevier Science Inc. All rights reserved.
Pneumatization of the Concha Inferior as a Cause of Nasal Obstruction
(int Rhinologic Soc, 2001) Çankaya, H; Egeli, E; Kutluhan, A; Kiris, M
Chronic nasal obstruction is a common disorder. Hypertrophy of the inferior turbinates is responsible for nasal obstruction more frequently than it is commonly thought. A pneumatized inferior turbinate has recently been described as a cause for nasal obstruction and only two cases have been reported until now. Inferior nasal turbinate develops by endochondral ossification of components of the mesethmoid and ectethmoid. The chondral framework of the inferior turbinate consists of a double lamella and two separate ossification centers that develop between the fifth and seventh month of fetal life. The separate ossification centers meet by the eighth fetal month. During ossification, the inferior turbinate detaches from the ectethmoid and becomes an independent bony structure. During that time the epithelium may misinvaginate into double lamellas and such double lamellas formed by the inferior turbinate may become persistent. A patient was referred to our clinic with headaches and nasal obstruction. A CT scan was performed which showed that the right lower concha was pneumatized. The headache of the patient disappeared after partial resection of the the lower and middle turbinate.
Use of the Laryngeal Mask To Evaluate a Laryngeal Web
(Springer verlag, 1999) Çankaya, H; Kati, I; Egeli, E; Demirel, CB