Browsing by Author "Erbin, A."

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A Prospective Analysis of the Efficacy and Safety of Caudal Block for Transrectal Ultrasound Guided Prostate Biopsy in Patients With Anorectal Disorders
(Yuzuncu Yil Universitesi Tip Fakultesi, 2024) Aslan, R.; Günes, H.Y.; Erbin, A.; Eryilmaz, R.; Sevim, M.; Ertaş, K.; Taken, K.
In this study, the efficacy and safety of the caudal block technique for transrectal ultrasonography-guided biopsy (Trus-guided biopsy) in patients with anorectal problems were investigated. A total of 31 consecutive patients with anal-rectal problems underwent prostate needle biopsy. All patients included in the study were examined by an experienced general surgeon, and the presence of anorectal problems was confirmed. The majority of patients (61%) were referred from the outer center to our clinic beca use a biopsy could not be performed due to severe pain felt during rectal probe insertion despite local anesthesia (topical prilocaine or lidocaine cream). A 12-core biopsy protocol was applied to all patients under the caudal block. Pain perception was se parately assessed during caudal anesthesia, probe insertion, and sampling stages using a visual analog scale (VAS) score. The mean age was 64.1 ± 9.1 years. The mean VAS score during caudal anesthesia was 1.8 ± 0.81. At probe insertion, the mean VAS score was 1,44 ± 012. During the needle penetration into prostate tissue and sampling, the mean VAS score was 2.44± 013. All of the patients did not state any bothersome pain at any stage. We did not find any complications related to the anesthesia method. Topical creams and/or periprostatic nerve block (PNB) do not provide adequate analgesia in patients with anorectal disorders undergoing Trus-guided biopsy. Caudal block technique can be performed effectively and reliably in this selected patient group. © 2024, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Relationship Between Serum Asymmetrical Dimethylarginine Level and Urolithiasis
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Yazici, O.; Aydin, K.; Temizkan, S.; Narter, F.; Erbin, A.; Kafkasli, A.; Sarıca, K.
In the present prospective clinical human study, we focused on researching whether or not there is a difference between metabolic syndrome (MS) positive/negative and renal stone disease (SD) positive/negative patients with regard to asymmetrical dimethylarginine (ADMA) serum levels to clarify the possible effect of endothelial cell dysfunction on renal SD. We included 76 patients (17 males and 59 females) who were admitted to the endocrinology and urology outpatient clinic between December 2014 and February 2018. Patients were segregated into 4 groups; group 1; MS (–) SD (-), group 2; MS (–) SD (+), group 3; MS (+) SD (-) and group 4; MS (+) SD (+). Patients’ age, sex, medical history, and anthropometric measurements were recorded. Endothelial dysfunction was assessed with serum ADMA levels. The mean age was 40.1 ± 11.4 years (range: 18–59). There was a statistically significant difference between groups for mean homocysteine, uric acid and BMI values. However, there was no statistically sign ificant difference between groups for mean CRP, age and creatinine values. The mean ADMA value was 152 ± 77 (range: 51–445). There was no statistically significant difference between groups for the mean ADMA values. These results showed that studies must focus on MS components separately from each other and sex distribution between patients must be homogeneous or different sexes must be examined separately. In addition, stone compositions of patients enrolled in the study must be known to arrive at more trustworthy and worthwhile results. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.