Browsing by Author "Erdoğan, E."

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The Association of Left Ventricular End-Diastolic Pressure and Acute Left Ventricular End-Diastolic Pressure Change With Miyocardial Blush Grade and St Segment Resolution in Stemi Patients Undergoing Primary Percutaneous Intervention
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Çap, M.; Erdoğan, E.; Karagöz, A.; Doğan, C.; Acar, R.D.; Unkun, T.; Ozdemir, N.
Elevated left ventricular end-diastolic pressure (LVEDP) is associated with adverse outcomes among those patients with ST-elevation myocardial infarction (STEMI).We aim to investigate the acute change of LVEDP in patients with STEMI and the relationship between LVEDP and early reperfusion parameters, such as ST-segment resolution (STR%) and myocardial blush grade (MBG). A total of 51 consecutive patients with STEMI who had undergone successful primary percutaneous coronary intervention (pPCI) with TIMI flow grade 3 were included in the study. LVEDP measurements were performed at the beginning (pre-pPCI LVEDP) and end of (post-pPCI LVEDP) the pPCI. MBG was defined after a successful pPCI; STR% was calculated 60 minutes after pPCI. The mean pre-pPCI LVEDP was 22.1 ± 4.8 mmHg and the post-pPCI LVEDP was 19.4 ± 4.8 mmHg. There was a mean 2.7±1.8 mmHg decrease in LVEDP values after pPCI which was statistically significant (95% CI -3.2, -2.2, p value< 0.001). Post-pPCI LVEDP median value was 19 mmHg. The patients were divided into two groups according to median value: There were 26 (51%) patients with post-pPCI LVEDP≤ 19 mmHg and 25 (49%) patients with post-pPCI LVEDP> 19 mmHg. STR% and MBG were significantly different between the two groups (p= 0.03 and p= 0.01). Post-pPCI LVEDP had a moderate negative correlation with MBG (r= -0.438) and STR% (r= -0.501). In this study, we demonstrated that primary PCI might substantially reduce the LVEDP level. Moreover, the LVEDP levels achieved after PCI might be associated with myocardial reperfusion, assessed by STR% on ECG and MBG during angiography. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
An Automated User-Friendly Software for Fast Computation of Blood Flow Velocity From Coronary Angiographic Images
(SAGE Publications Inc., 2025) Çap, M.; Karaduman, M.; Zhou, T.; Erdoğan, E.; Tanboğa, İ.H.; Tufaro, V.; Bourantas, C.V.
Thrombolysis in myocardial infarction frame count enables assessment of coronary flow but cannot measure coronary flow velocity (CFV), which is needed to examine microvascular function. To overcome this limitation, we introduce a semi-automated software for fast CFV computation using contrast bolus tracking techniques in angiography and compare its performance against experts. The study included patients undergoing coronary angiography. Two experts measured the CFV using the number of frames, segment length, and frame rate. Measurements were repeated for shorter segments and different projections, and their estimations were compared with the software. In total, 123 patients (152 vessels) were included. The software had excellent reproducibility in measuring CFV (intraclass correlation coefficient (ICC) =.995), which was superior to experts (ICC =.946) and provided similar estimations irrespective of the segment length (ICC =.992); conversely, the experts overestimated CFV in short segments. The reproducibility of the experts and the software was moderate when comparing CFV measurements in different projections (first expert vs software ICC =.807, second expert vs software ICC =.790, first expert vs second expert ICC =.885). The software provides reproducible CFV estimations that are close to experts’ estimations. Further validation against wire-based functional techniques is needed to examine its potential in assessing microvascular function. © The Author(s) 2025.
Impact of Youtube Platform in the Realm of Interventional Cardiology Techniques Such As: Double Kissing Crush
(Yuzuncu Yil Universitesi Tip Fakultesi, 2021) Ozkalaycı, F.; Erdoğan, E.
Internet has become a widely used resource for obtaining medical information. However, the quality of information on online platforms is still debated. Our goal is to evaluate YouTube video platform regarding its' usefulness and reliability in terms of teaching the steps of Double kissing crush (DK-crush) technique. “DK-crush”, “DK-crush stenting technique”, “DK-crush technique” were the key words queried on the search bar of http://www.YouTube.com. All the videos were screened and those videos in English and Turkish and those videos without voice yet involves the explanation of DK-Crush technique were included. Each video was scored according to the reference article in which the steps of the technique were explained in detail. According to the steps in the reference article, the videos were scored. One point was given for each step shown and 0 for those steps that are not demonstrated, therefore the "total DK-crush step score" (TDCS) was calculated for each video. Our aim was to evaluate the compatibility of the videos with the reference article. In addition, it was aimed to evaluate videos with HONcode, JAMA benchmark and modified DISCERN tools which are instruments to evaluate the reliability, credibility and quality of the medical information served on the internet. A total of 26 videos met inclusion criteria and were included in the analysis. The median number of views of the videos was 1037 (IQR 194 to 4930) with a median duration of 8.55(IQR 3.19 to 15.2). The median number of the criteria consistent with the reference criteria was 12 (IQR 9,25 to 12), most videos met all the essential criteria and have certain amount of correlation with the scoring systems. Although most videos were compatible with the reference technique, we found mild correlation between modified Discern score and total DK-Crush step score. Furthermore when comparing the number of views, likes, duration of video, HONcode score and the total DK-crush step score(TDCS) were likely to be higher in the videos downloaded or presented by individuals with academic degrees.( p:0.004,p:0.02, p:0.02, p:0.02, p:0.03 respectively). All of the videos on DK crush was prepared by healthcare professionals yet not all the uploaders or presenters in the videos have academic titles. Those videos in which DK-Crush technique was performed and presented by those with academic degrees are likely to be more instructive according to our results. Compared to the reference publication, most videos were compatible in terms of fitting the procedural steps of DK-crush. Among all videos HONcode and JAMA score has no correlation with DK-Crush step scores, yet modified Discern has mild correlation with total DK-crush step score. © 2021, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Medikal Sempatektomi Yapılan Sıçanlarda Duktus Deferens Histomorfolojisi ve Epididimal Sperm Değerlendirmesi
(2002) Erdoğan, E.; Göçer, F.; Rağbetli, M. Ç.; Odabaş, Ö.; Özbek, H.; Aydınlıoğlu, A.
Bu çalışmamızda medikal sempatektomi yapılan sıçanlarda duktus deferensteki histomorfolojik değişikliklerle, kaput ve kauda epididimisteki sperm konsantrasyon ve hareketliliğindeki değişimin araştırılmasını amaçladık. Çalışmada 18'i çalışma grubunda ve 12'si kontrol grubunda olmak üzere toplam 30 adet erişkin Spraque-Dawley erkek sıçan kullanıldı. Çalışma grubuna 15 gün süreyle düşük doz (10mg/kg/gün) intraperitoneal guanethidin (CIBA), kontrol grubuna ise serum fizyolojik enjeksiyonu yapıldı. 15. günde eter anestezisi altında bilateral orşiepididimektomi yapıldı. Her iki grupta sağ taraftan çıkarılan spesimenler epididimal sperm hücresi sayımında, sol taraf ise vaz deferensin histomorfolojik incelemesinde kullanıldı. Kaput ve kaudadaki sperm sayıları çalışma grubunda kontrole göre daha düşük olmakla birlikte istatistiksel olarak anlamlı değildi (p>0.05). Her iki grup sperm hareketliliği yönünden karşılaştırıldığında hem kaput hem de kaudal sperm hücreleri arasında fark yoktu (p>0.05). Bu sonuçlara karşın sempatektomili grupta duktus deferens kas tabakası ve epitel yüksekliğinde azalma ve tümenlerinde genişleme gözlenmiştir. Sempatektomi yapılan sıçanlarda kaput ve kauda epididimisteki sperm yoğunluğu ve hareketliliğinde değişiklik saptanmazken duktus deferens histomorfolojisinde anlamlı değişiklikler bulunmuştur.