Browsing by Author "Erdogan, Songul"

Now showing 1 - 2 of 2

Comparative Clinical Efficiency of Resveratrol, Allopurinol, and Resveratrol Plus Allopurinol in Canine Visceral Leishmaniasis
(Amer veterinary Medical Assoc, 2025) Erdogan, Songul; Erdogan, Hasan; Ural, Kerem; Pasa, Serdar; Gultekin, Mehmet; Balikci, Canberk; Gunal, Ismail
Objective To assess the clinical and immunological effectiveness of resveratrol alone or combined with allopurinol for treating canine visceral leishmaniasis (CVL). Methods This study included 50 dogs, 30 diagnosed with CVL and 20 healthy controls. Dogs were classified based on their treatment regime (receiving resveratrol [200 mg/dog/d] and/or allopurinol [10 mg/kg/d]). Clinical scores, antileishmanial antibody titers, and routine blood parameters were evaluated on days 0, 15, and 30 after treatment. Results Dogs treated with the combination therapy showed the most substantial improvements, with a 75.77% reduction in clinical scores and an 81.25% reduction in antibody titers. Dogs receiving allopurinol exhibited a 56.25% reduction in clinical scores, while those treated with resveratrol showed a 42.82% reduction. Antibody titers were less signifi-cantly reduced in the resveratrol group (67.5%) compared to the allopurinol group (45%). Conclusions Combining resveratrol with allopurinol enhances the therapeutic efficacy for CVL, leading to significant clinical im-provements and reductions in antibody titers. Resveratrol alone also demonstrates promising anti-leishmanial effects. Clinical Relevance Resveratrol, either alone or in combination with allopurinol, offers a feasible and effective alternative for improving clinical outcomes in CVL. Its incorporation into standard protocols may enhance treatment strategies in veterinary medicine.
Feasibility of Clear-Up Strips in the Diagnosis of Demodex and Sarcoptes Mites
(Health & Environment Assoc, 2019) Ayan, Adnan; Erdogan, Songul; Ural, Kerem; Erdogan, Hasan; Gul, Gizem
In the present study, it was aimed to compare the atraumatic Nivea nasal clear-up (NNC) band and traumatic deep skin scraping test (DSST) for the diagnosis of Demodex canis or Sarcoptes scabiei in dogs. A total of 12 specimens were collected from six dogs diagnosed with demodicosis (n=5) or sarcoptic mange infestation (n=1) between September-December 2016 with both techniques. The total number of mites in demodectic dogs with two different methods (NNC) band and DSST were 286 and 159, respectively. In addition, only four eggs were identified with DSST, while 16 adult mites and eight eggs were identified with (NNC) band in a dog with sarcoptic mange. When both technical comparative interpretations are made, it can be said that (NNC) band might be a method which can easily be used in the diagnosis of both diseases and might be used more frequently than DSST. In addition, the atraumatic formation of the application may increase satisfaction of the patient owner.