Browsing by Author "Eren, B."

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Effects of Age and Co-Morbidities on Complication Rate in Surgical Treatment of Lumbar Degenerative Diseases: a Prospective Clinical Study
(Yuzuncu Yil Universitesi Tip Fakultesi, 2023) Tufan, A.; Aktaş, Ö.Y.; Eren, B.; Doruk, E.; Gulec, I.; Taş, A.; Guzey, F.K.
Surgery for lumbar degenerative diseases is increasingly more common due to ageing of the population. There were conflicting results on effects of complication rates of ageing and presence of comorbidities in these o perations in literature. Presence of systemic co-morbidities, smoking, body mass index (BMI), American Society of Anaesthesiologists score, length of hospital before and after operation and in intensive care unit (ICU), number of decompressed levels (nD), addition of instrumentation, operation time, blood loss, presence of transfusion, surgical and systemic complications seen during the operation and during one month after operation, and requirement of a new operation were recorded in 277 patients (61.6±8.8 years of age, male/female ratio 78/199) operated for lumbar degenerative diseases between 2014 and 2016. Total 96 out of 277 patients (34.6%) had complications and 1 patient died. The most frequent complications were dural tear (36 cases, 12.9%), wound problems without infection (34 cases, 12.2%), screw malposition (15 cases, 5.4%), and systemic complications (21 cases, 7.5%). The risk factors were diabetes mellitus (DM) for major complications, BMI and nD for minor complications, and nD for systemic complications. All other factors including age did not affect the complication rate. Regression analyses revealed that the only efficient factor was BMI for presence of overall and minor complications. It was found that the advanced age did not cause to increase complication rates. The efficient factors for complication rates were DM, BMI and nD. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Treatment and Outcomes of Patients With Metastatic Spinal Cord Compression: a Double-Center Study
(NLM (Medline), 2023) Aycan, A.; Eren, B.; Tas, A.; Celik, S.; Karagoz Guzey, F.; Kuyumcu, F.; Aycan, N.
OBJECTIVE: Spinal metastases may only affect the bone tissue and result in spinal instability or may additionally result in epidural compression, leading to neurological deficits. Surgery has emerged as a popular method in treating metastatic epidural spinal cord compression (MESCC) due to the advances in surgical techniques and instrumentation. In this study, we evaluated patients with MESCC regarding neurological status, pain status, and survival rates, and presented our experience managing MESCC. PATIENTS AND METHODS: Clinical and radiographic records of 53 patients diagnosed with MESCC between January 2011 and March 2017 were retrospectively evaluated. The study included patients with a pathological diagnosis of primary cancer, those who complained of spinal metastasis, and those who had indications of MESCC on Magnetic Resonance Imaging (MRI). Bone structure and spinal stability were evaluated using assessed Computed Tomography (CT), and metastatic spread was considered using assessed Positron Emission Tomography (PET) in suitable cases. For each patient, the presence of a tumor compressing the spinal cord, age, gender, preoperative, and postoperative American Spinal Injury Association scores (ASIA), Tokuhashi prognostic score (TPS), affected spinal segment, pathological diagnosis, preoperative, and postoperative Visual Analog Scale (VAS), the status of spinal stability, follow-up period, and complications were evaluated. RESULTS: Forty-five patients (82.2% of them were women) underwent surgery with a mean age of 58.29 ± 15.14 years. The most frequent type of primary tumor was multiple myeloma (33.9%), followed by lung (24.6%), gastric (7.5%), and prostate (5.7%). The most common site of metastasis was the thoracic region (43.4%), followed by lumbar (24.5%), multiple (24.5%), and cervical (5.7%). The analysis indicated that a significant difference was found between the survival rates of the TPS categories. CONCLUSIONS: Common symptoms of MESCC include spinal pain and neurological deficit below the level of the injury. Prompt surgical treatment followed by oncological treatment leads to significant neurological recovery, more prolonged survival, pain relief, and improved quality of life in patients with a short survival time. Oncological treatments, including radiotherapy (RT), should be recommended after surgical treatment.