Browsing by Author "Eroglu, Cennet Neslihan"
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Article Assessment of Prevalence and Volumetric Estimation of Possible Stafne Bone Concavities on Cone Beam Computed Tomography Images(Springer, 2020) Koc, Alaettin; Eroglu, Cennet Neslihan; Bilgili, ErsenObjectives Our study aimed to determine the prevalence and volumetric estimates of Stafne bone cavities (SBC) on cone beam computed tomography (CBCT) images. Methods This retrospective study, which involved the CBCT images of 1141 men and 1260 women with an age range of 10-90 years, aimed to determine the prevalence of SBCs and to calculate their volumes using the semi-automatic segmentation method. Results A total of 15 SBCs were diagnosed in 14 patients. Among the detected SBCs, 7.14% were found in a female patient and 92.86% were found in 13 male patients. Of the total number of SBCs, 6.67% were anteriorly located and 93.33% were posteriorly located. Bilateral SBCs had a prevalence of 0.04%; unilateral posterior SBCs 0.54% and anterior SBCs 0.04%. The mean SBC volume was calculated as 338.05 mm(3). Conclusions The results of our study showed that SBC is a rare anomaly. In contrast to two-dimensional imaging techniques, CBCT allows a precise determination of SBCs' pattern of impact on adjacent bony structures, relationship with the mandibular canal and dimensions.Article Clinical and Histological Evaluation of the Efficacy of Antimicrobial Photodynamic Therapy Used in Addition To Antibiotic Therapy in Pericoronitis Treatment(Elsevier Science Bv, 2018) Eroglu, Cennet Neslihan; Tunc, Serap Keskin; Erten, Remzi; Usumez, AshhanBackground: Although antimicrobial efficacy of photodynamic therapy has been studied several times, there is no study investigating its efficacy on pericoronitis. This study aimed to determine whether antimicrobial photodynamic therapy combined with antibiotic therapy is clinically and histologically superior to antibiotic therapy alone in pericoronitis treatment. Methods: Patients (n = 40) with pericoronitis were divided into two groups (20 patients for each) to receive either antibiotic + indocyanine green + 810 nm wavelength diode laser (antimicrobial photodynamic therapy group) or antibiotic alone. Initial biopsy samples were obtained from the affected tissue of the patients at their first presentation to the clinic before any intervention. The second biopsy samples were obtained on the 3rd day of treatment in both groups from the tissue part not biopsied before; tooth extraction was then performed. All tissue samples were histologically examined to assess inflammatory cell response. Patients' pain (using Visual Analogue Scale) and lymphadenopathy (presence or absence) were clinically evaluated in the first 3 days and on the 7th day of treatment. Results: In the antimicrobial photodynamic therapy group, 100% improvement was achieved regarding pain and lymphadenopathy at the end of the 7th day. Comparison of the inflammatory cell scores of the 2nd biopsy samples between the antibiotic alone and antimicrobial photodynamic therapy groups revealed a significant difference in favor of antimicrobial photodynamic therapy group. Conclusions: Antimicrobial photodynamic therapy combined with antibiotic therapy for pericoronitis treatment was found to be more successful as compared with the antibiotic therapy alone regarding clinical and histological outcomes.Article Clinical Evaluation of Single and Repeated Sessions of Photobiomodulation With Two Different Therapeutic Wavelengths for Reducing Postoperative Sequelae After Impacted Mandibular Third Molar Surgery: a Randomized, Double-Blind Clinical Study(Univ Sao Paulo Fac Odontologia Bauru, 2021) Yuksek, Mehmet Nuri; Eroglu, Cennet NeslihanThe effects of the number of photobiomodulation (PBM) sessions on the postoperative inflammatory process remain controversial. The current literature comparing single and repeated PBM sessions is limited. Objective: This study aimed to compare the effects of single and repeated PBM sessions, applied at two different therapeutic wavelengths within the infrared spectrum, on postoperative inflammatory response after impacted third molar tooth extraction. Methodology: This randomized, double-blind clinical study included 40 patients with bilateral impacted mandibular third molars (80 teeth). The patients were divided into two groups each including 20 subjects (40 teeth) to receive either single-session laser at 810 nm (20 teeth) and 940 nm (20 teeth) immediately after the surgery or repeated laser sessions at 810 nm (20 teeth) and 940 nm (20 teeth) (immediately after the surgery and on postoperative Day 1). Lasers at 940 nm (power density 0.5 Watt/cm2, energy density 4 J/cm2 for a time until the cumulative energy on the device screen reaches 50 J from 0 J, in continuous mode, spot size 2.8 cm2) and at 810 nm (power density 0.14 Watt/cm2, energy density 4 J/cm2, for 30 seconds, in continuous mode, spot size 2.1 cm2) were applied intra- and extra-orally. Pain, swelling, and trismus were evaluated postoperatively. Results: No significant differences were determined between the groups on the evaluated parameters (p>0.05). Conclusion: Within the study limitations, in PBM, the effects of 810 nm and 940 nm and those of single and repeated applications were similar regarding pain, swelling and trismus. Immediate postoperative PBM could be preferred to repeated applications performed by point application within a 24-hour period.Article Comparison of Clinical Efficacies of Preoperatively Initiated Naproxen Sodium-Codeine Phosphate in Combination, Diclofenac Potassium, and Benzydamine Hydrochloride for Pain, Edema, and Trismus After Extraction of Impacted Lower Third Molar: a Randomized Double-Blind Study(W B Saunders Co-elsevier inc, 2018) Cigerim, Levent; Eroglu, Cennet NeslihanPurpose: The aim of this study was to compare the clinical efficacies of naproxen sodium-codeine phosphate in combination, benzydamine hydrochloride, and diclofenac potassium for pain, edema, and trismus after lower third molar extraction. Materials and Methods: Ninety healthy volunteers in whom impacted third molar extraction was indicated were randomly distributed into 3 groups. One hour before the tooth-extraction process, patients were administered one of the following drugs: naproxen sodium, 550 mg, and codeine phosphate, 30 mg, in a tablet; diclofenac potassium, 50 mg, in a coated pill; or benzydamine hydrochloride, 50 mg, in a coated pill. Pain assessment was conducted via a visual analog scale; edema assessment, by measuring the distances between predetermined facial landmarks; and trismus assessment, by measuring interincisal distance. Regarding rescue analgesics (paracetamol, 500 mg), the number and time of use by patients were recorded. Results: Naproxen sodium-codeine phosphate was more effective for pain, edema, and trismus than diclofenac potassium and benzydamine hydrochloride (P < .05). Benzydamine hydrochloride yielded similar clinical responses to diclofenac potassium (P > .05). No drug-related side effects were observed. Conclusions: Naproxen sodium-codeine phosphate constitutes the drug of choice after the extraction of a patient's impacted lower third molar. Benzydamine hydrochloride has similar efficacy to diclofenac potassium, and it can be used as a nonsteroidal anti-inflammatory analgesic drug. (C) 2017 American Association of Oral and Maxillofacial SurgeonsArticle Comparison of the Analgesic Efficacy of Spray and Tablet Flurbiprofen for Pain After Soft Tissue Surgery(Sociedade Brasileira de Pesquisa Odontologica, 2024) Eroglu, Cennet Neslihan; Yuksek, Mehmet Nuri; Elasan, Sadi; Mizrak, Yusuf Rodi; Karaca, BusraThe aim of this randomized clinical study was to assess the comparative efficacy of flurbiprofen in tablet and spray formulations for postoperative pain management in oral soft tissue wounds undergoing primary closure while investigating the feasibility of achieving optimal analgesia with reduced dosage and risk. Forty patients who underwent epulis fissuratum and frenulum excision for pre-prosthetic surgery were randomly assigned to receive either tablet or spray forms of flurbiprofen. The lesion dimensions were measured preoperatively, followed by excision and primary closure. The tablet group received oral tablets containing 100 mg of flurbiprofen twice daily, whereas the spray group received an oral spray containing 0.25% flurbiprofen, administered as two sprays thrice daily. Postoperative pain was assessed using the Numerical Rating Scale (NRS) until the 7th day. Lesion size, drug consumption, and rescue analgesic use were compared between the groups. There were no statistically significant differences in the lesion size between the groups. However, the mean NRS score in the spray group was significantly lower in the spray group compared to than that in the tablet group at 6th hour postoperatively (p = 0.037). Significant differences favoring the tablet group were observed in the first three doses of the drug (p = 0.001). No patients required rescue analgesics. The spray formulation of flurbiprofen demonstrated effective and safe pain relief in oral soft tissue wounds undergoing primary closure, with no reported adverse effects.Article Comparison of the Effects of Daily Single-Dose Use of Flurbiprofen, Diclofenac Sodium, and Tenoxicam on Postoperative Pain, Swelling, and Trismus: a Randomized Double-Blind Study(W B Saunders Co-elsevier inc, 2016) Kaplan, Volkan; Eroglu, Cennet NeslihanPurpose: The aim of the present study was to compare the effects of daily single-dose use of flurbiprofen, diclofenac sodium, and tenoxicam on pain, swelling, and trismus that occur after surgical extraction of impacted wisdom teeth using local anesthesia. Materials and Methods: The present study included 3 groups with 30 patients in each group. Those volunteering to participate in this double-blind randomized study (n = 90) were selected from a patient population with an indication for extraction of impacted wisdom teeth. Group 1 patients received 200 mg flurbiprofen, group 2 patients received 100 mg diclofenac sodium, and group 3 patients received 20 mg tenoxicam. All doses were once a day, starting preoperatively. Pain was evaluated postoperatively at 1, 2, 3, 6, 8, and 24 hours and at 2 and 7 days using a visual analog scale (VAS). For comparison with the preoperative measurements, the patients were invited to postoperative follow-up visits 2 and 7 days after extraction to evaluate for swelling and trismus. The statistical analysis was performed using descriptive statistics in SAS, version 9.4 (SAS Institute, Cary, NC), software. Statistical analysis of the pain, swelling, and trismus data was performed using the Kruskal-Wallis, Dunn, and Wilcoxon-Mann-Whitney U tests. The statistical level of significance was accepted at P =.05 and power of 0.80. Results: Clinically, tenoxicam showed better analgesic and anti-inflammatory efficacy compared with diclofenac sodium and, in particular, flurbiprofen. Although the VAS scores in the evaluation of pain showed statistically significant differences at 2 days, no statistically significant difference was found for swelling and trismus. Conclusions: Our study evaluated the analgesic and anti-inflammatory effects with a daily single dose of flurbiprofen, diclofenac sodium, and tenoxicam. Daily 20 mg tenoxicam can be accepted as an adequate and safe option for patients after a surgical procedure. (C) 2016 American Association of Oral and Maxillofacial Surgeons.Article Comprehensive Analysis of Bone Tissue in Extraction Sockets of Third Molars After Leukocyte and Platelet Rich Fibrin and Photobiomodulation Applications(Springer Heidelberg, 2024) Demirok, Sevgi Ozan; Eroglu, Cennet Neslihan; Koc, AlaettinObjectivesThe aim of this study was to compare leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation (PBM) applications, which have been repeatedly reported to be superior to control groups, in terms of pain, soft tissue and bone healing in tooth extraction sockets.Materials and methodsThis double-blind, randomized clinical study was completed with 34 patients, who had an indication for extraction of their bilaterally impacted teeth. The right and left teeth of the patients were randomly divided into L-PRF and PBM groups. L-PRF group was treated with the blood product centrifuged for 12 min at 2700 rpm, and the PBM group was treated with a diode laser at different points for 60 s with a wavelength of 940 nm in repeated sessions. Postoperative pain was evaluated using Visual Analogue Scale (VAS), soft tissue healing with Landry Index (LI), tissue healing in the distal region of mandibular second molar by probing depth measurement, and bone healing via panoramic x-ray using the Image J program.ResultsNo statistically significant difference was found for any variable compared between the groups.ConclusionL-PRF and PBM applications provide similar support in the healing of extraction sockets. Nevertheless, the advantages and disadvantages of both methods determine their usage areas.Clinical relevanceWhile L-PRF is advantageous in the early healing of extraction sockets, PBM may be preferred in terms of bone trabeculation in the long term.Article Effectiveness of Single Session of Low-Level Laser Therapy With a 940nm Wavelength Diode Laser on Pain, Swelling, and Trismus After Impacted Third Molar Surgery(Mary Ann Liebert, inc, 2016) Eroglu, Cennet Neslihan; Tunc, Serap KeskinIntroduction: In low-level laser therapy (LLLT), applications are generally performed in repetitive sessions using wavelengths of around 800nm, at which the depth of penetration of laser is greater. The present study aimed to investigate the effects of LLLT with a 940nm diode laser, which was performed extraorally on all the primarily and secondarily affected areas immediately after surgery in a single session, on pain, swelling, and trismus that occurred after impacted tooth extraction. Materials and methods: Thirty-five outpatients with similarly impacted lower third molars on both sides were selected. The teeth of patients were removed in two separate operations. Postoperatively, the patients received laser therapy with energy of 4J/cm(2) on one side and no laser energy was applied to the other side (placebo side). Swelling, trismus, and subjective assessment of pain on a visual analog scale were evaluated and compared between the laser-treated and placebo sides. Results: There was no statistically significant difference in pain, swelling, or trismus between the sides (Mann-Whitney U test p>0.05). However, according to the clinical outcomes, swelling and trismus were less in the laser-treated side than in the placebo side. Conclusions: A single-session LLLT that would be applied with a diode laser immediately after impacted tooth extraction might help patients to be less affected by postoperative trismus and swelling.Article Removal of Epulis Fissuratum by Er,cr:ysgg Laser in Comparison With the Conventional Method(Mary Ann Liebert, inc, 2015) Eroglu, Cennet Neslihan; Tunc, Serap Keskin; Elasan, SadiObjective: The present study aimed to compare clinical outcomes during the recovery period after soft tissue surgery performed by an erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser with those after surgery with the conventional method, in which a scalpel was used. Methods: A total of 44 epulis fissuratum removal surgeries were performed in 30 healthy volunteers using either an Er,Cr:YSGG laser (laser group) or a scalpel (conventional group), with the same number of lesions in each group. Both groups were controlled postoperatively on days 2, 7, 14, and 30. The visual analog scale (VAS) pain scores of the patients and healing, erythema, and suppuration in the surgical area were recorded with scores between 0 and 3. Total wound surface was measured by a ruler according to the Bates-Jensen Wound Assessment Tool. Results: The results of the present study demonstrated that there were no significant differences between the conventional group using analgesic and the laser group in terms of the VAS scores (p=0.744) and edema (p=0.206). Evaluation of wound surface revealed healing without any problem as of the 2nd day at a rate of 82% in the laser group and 59% in the conventional group. Conclusions: In conclusion, Er,Cr:YSGG laser was superior to scalpel regarding clinical outcomes, and led to a difference in the use of analgesic and local anesthetic.Article Soft Tissue Schwannomas of the Hard Palate and the Mandibular Mentum(Hindawi Ltd, 2017) Eroglu, Cennet Neslihan; Tunc, Serap Keskin; Gunhan, OmerSchwannomas are benign, slow growing, encapsulated tumours that originate from the Schwann cells. Intraoral schwannomas are rare, and most of these tumours involve the tongue. They are rarely located in the hard palate or in the facial soft tissue. Herein, we present the clinical and histological features as well as the prognoses of two male patients with schwannoma, one of which was localized to the hard palate and the other to the facial soft tissue around the mandibular mentum and caused swelling.Article Treatment of Aphthous Ulcers With Photodynamic Therapy: a Randomized Controlled Clinical Study(Elsevier, 2024) Eroglu, Cennet Neslihan; Feslihan, Erkan; Karaca, Busra; Elasan, SadiBackground: This study aims to assess whether photodynamic therapy (PDT) offers a clinically effective alternative for treating oral aphthous ulcers, contributing to the ongoing quest for methods to expedite their treatment process amidst the limited understanding of their etiology. Materials and Method: The study involved thirty volunteers with aphthous ulcers, split equally between a control group and a PDT group. Patients in the PDT group received laser treatment using Indocyanine green upon admission, while the control group received no intervention. Lesion diameter was measured at presentation and on the 3rd, 5th, and 7th days for all patients, with wound healing assessed on the 7th day. Additionally, pain levels were evaluated using the Visual Analog Scale (VAS) preoperatively and on the 1st, 3rd, 5th, and 7th days for the PDT group, and on the corresponding days for the control group. Results: Lesion diameters in the PDT group showed a significant reduction over time (p p = 0.001), particularly from preoperative to final measurements. The control group also exhibited a decrease, albeit slower (p = 0.001). The 7th-day healing scores favored the PDT group significantly (p p = 0.012). VAS scores in the PDT group decreased significantly over time (p p = 0.001), indicating pain reduction. A similar trend was observed in the control group, albeit slower. Between-group differences in healing data and pain data were statistically significant. Conclusion: PDT proves effective in reducing aphthous ulcer diameters and pain intensity, facilitating faster healing than the control group. These results advocate for PDT as a viable treatment option for aphthous lesions.