Browsing by Author "Ersoz, Muhammet Eren"

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Biochemical Changes Associated With Temporomandibular Disorders
(Sage Publications Ltd, 2019) Demir, Canser Yilmaz; Ersoz, Muhammet Eren
Objective To assess vitamin D, parathyroid hormone, calcitonin, calcium, phosphorus and magnesium levels in patients with versus without temporomandibular disorders (TMDs). Methods This prospective observational study included patients with TMDs and age-matched healthy controls. TMDs were diagnosed via physical and radiologic examination, and serum levels of 25 (OH) vitamin D, parathyroid hormone, calcitonin, calcium, magnesium, and phosphorus were determined. The impact of age, sex and seasonal variations in serum 25 (OH) vitamin D levels was controlled by the inclusion of age, sex and date-matched control patients. Results The study included 100 patients, comprising 50 patients with TMDs and 50 control patients. No statistically significant between-group differences were found regarding age or sex. No statistically significant between-group differences were found in terms of serum 25 (OH) vitamin D, calcitonin, calcium, magnesium or phosphorus levels. Parathyroid hormone levels were statistically significantly higher in patients with TMDs versus healthy control patients. Conclusion In patients with temporomandibular disorders, increased parathyroid hormone levels in response to vitamin D deficiency was significantly more prominent. These data suggest that, in patients with temporomandibular disorders, vitamin D deficiency should be assessed and corrected.
Comparison of Enalapril, Candesartan and Intralesional Triamcinolone in Reducing Hypertrophic Scar Development: an Experimental Study
(Springer, 2018) Demir, Canser Yilmaz; Ersoz, Muhammet Eren; Erten, Remzi; Kocak, Omer Faruk; Sultanoglu, Yilmaz; Basbugan, Yildiray
The purpose of this study was to compare the effects of oral enalapril, an angiotensin-converting enzyme inhibitor (ACE-I), oral candesartan, an angiotensin receptor blocker (ARB), and intralesional corticosteroid treatments in reducing scar formation. Twenty male rabbits were divided into five study groups: A (sham), B (control), C (ACE-I), D (ARB) and E (intralesional corticosteroid). The rabbit ear hypertrophic scar model was used. The hypertrophic scars were photographed and analyzed with the program ImageJ quantitatively to determine the degree of collagen fibers. The scar elevation index (SEI) was calculated at the end of the 40th day. Tissue samples were stained with hematoxylin and eosin and Masson's trichrome and examined under light microscopy for the determination of fibroblast number, epithelization, vascularization, inflammation and fibrosis. The SEI was the highest in the control group with the highest number of fibroblasts under the epithelium. In the steroid group, the SEI was significantly lower than both the ACE-I (p: 0.02) and ARB (p: 0.001) groups. The density of type 1 collagen fibers was the lowest in the control group, whereas type 3 collagen fibers were highest in that group. The ACE-I and ARB groups were similar regarding densities of type 1 and type 3 collagen fibers. The density of type 1 collagen fibers was the highest in the steroid group, whereas the density of type 3 collagen fibers was the lowest in that group. Enalapril, candesartan and intralesional steroid therapies were all effective in reducing scar tissue development; however, enalapril and steroid groups revealed better results. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Groin Flap Experience in the Reconstruction of Soft Tissue Defects of the Hand
(Medknow Publications & Media Pvt Ltd, 2016) Yuce, Serdar; Oksuz, Mustafa; Ersoz, Muhammet Eren; Kocak, Omer Faruk; Kahraman, Ahmet; Isik, Daghan; Atik, Bekir
Objective: Pediculated groin flap has been playing an important role in hand reconstructive surgery for a long time. In this study, the cases where pediculated groin flap in the reconstruction of soft tissue defects of the hand was used are presented in terms of literature. Material and Methods: The cases included in the study where a groin flap was used for hand defects between 2010 and 2014 in the Plastic, Reconstructive, and Aesthetic Surgery Department. The age, gender, reason of defect, its localization, groin flap size, donor area closure method, flap separation time, other treatments, and complications were thoroughly examined. Results: Twenty-two groin flaps were used in 13 male and 7 females. It was used to close the amputated part in 8 patients as a result of finger amputation and degloving injury, in 3 patients as a result of hand and finger crush defect, in 1 patient as a result of burn finger defect, in 5 patients for extension contracture, and in 3 patients for flexion contracture due to burn sequel. Flap loss was not recorded in any of the cases. Conclusion: Pediculated groin flap is a good alternative that can be easily and safely used in suitable cases and has an important place in the reconstruction of hand defects.
Inferior Pedicle Reduction Mammoplasty With or Without Tourniquet: a Comparative Study
(Springer, 2017) Demir, Canser Yilmaz; Sultanoglu, Yilmaz; Kocak, Omer Faruk; Ersoz, Muhammet Eren
To compare the perioperative findings of inferior pedicle reduction mammoplasty (IPRM) performed with or without a tourniquet. This study was carried out in the plastic and reconstructive surgery department at a tertiary care center on a total of 42 consecutive women scheduled for IPRM. Patients in Group I (n = 21) underwent surgery using a tourniquet, whereas patients in Group II (n = 21) were operated on without a tourniquet. Levels of hemoglobin (Hb), hematocrit (Hct), Hct/Hb ratio, and platelet counts were noted preoperatively and on postoperative 24th and 48th h. Numbers of surgical pads and gauze sponges completely used and dripping with blood were recorded. Duration of operation, the amount of breast tissue excised on both sides, and fluid collected in hemovac drains on 48th h after operation were documented. In Group I, the operative time was significantly shorter (p < 0.001), and numbers of gauze sponges and surgical pads were fewer (p < 0.001 for both). Hemoglobin levels were significantly higher in Group I on postoperative 24th (p = 0.002) and 48th h (p = 0.007). Similarly, hematocrit levels in Group I were higher than those of Group II on postoperative 24th (p = 0.004) and 48th h (p = 0.009). We determined that use of a tourniquet significantly reduced the operative time and blood loss during IPRM. Therefore, our preliminary results support that tourniquet usage is practical and safe, and it may also improve the cost-effectiveness of the procedure.
Is There a Role for Oxidative Stress in Temporomandibular Joint Disorders
(W B Saunders Co-elsevier inc, 2018) Demir, Canser Yilmaz; Kocak, Omer Faruk; Bozan, Nazim; Ersoz, Muhammet Eren; Demir, Halit
Purpose: Data on the role of oxidative stress in temporomandibular joint (TMJ) disorders are limited. This study compared serum levels of oxidative stress indicators and antioxidant enzymes in patients with TMJ disorders. Patients and Methods: In this prospective study, patients with TMJ disorders and healthy controls were compared for descriptive characteristics (age and gender) and serum levels of malondialdehyde (MDA), an oxidative stress marker, and antioxidant enzymes catalase (CAT), glutathione (GSH), and superoxide dismutase (SOD). Results: This study included 32 patients with TMJ disorders and 32 healthy controls. There were no differences between the 2 groups for age (P =.98) and gender (P =.599). MDA levels were higher in the TMJ disorders group than in the control group (P <.001), whereas serum levels of CAT, SOD, and GSH were significantly higher in the control group (P <.001 for all comparisons). There was no correlation between age or gender and MDA, SOD, CAT, and GSH levels in the TMJ disorders or control group. Conclusion: Oxidative stress markers might have promising potential as biomarkers in the diagnostic strategy and therapeutic targets of TMJ disorders. (C) 2017 American Association of Oral and Maxillofacial Surgeons
Spontaneous Flexor Tendon Rupture Developed in Neurofibromatosis
(Medknow Publications & Media Pvt Ltd, 2014) Yuce, Serdar; Kocak, Omer Faruk; Sultanoglu, Yilmaz; Ersoz, Muhammet Eren; Isik, Daghan
Neurofibromatosis is a disease with an autosomal dominant inheritance pattern and it affects different organ systems. In neurofibromatosis cases, cases with a spontaneous flexor tendon rupture depending on intratendinous neurofibroma proliferation in hand were reported. In our study, tendon rupture in the hand of 34-year-old female patient with neurofibromatosis was presented. Unlike literature in this case, we are of opinion that the disease has degenerative effect instead of neurofibroma mass effect of tendon rupture.
Use With Tissue Expander Face, Scalp and Neck Reconstruction
(Modestum Ltd, 2015) Yuce, Serdar; Oksuz, Mustafa; Ersoz, Muhammet Eren; Kahraman, Ahmet; Isik, Daghan; Atik, Bekir
The tissue expander has found widespread use in reconstructive surgery. The donor area is needed, the recipient site with similar characteristics (color, thickness, hair follicle) features, minimal scarring and leads to donor site morbidity. In our study, presented face, scalp and neck reconstruction results obtained with the use of expander. The face, scalp and neck areas expander was used to evaluate patients in the Plastic, Reconstructive and Aesthetic Surgery Department of Yuzuncu Yil University. Age, gender, expander indication, defect or scar area localization, expander residential area, expander shape, volume, valve location (internal-external), expansion time, major and minor complications were reviewed. 30 number expanders were used in 17 patients (8 male, 9 female patients). Expanders were used burn sequelae in 14 patients, tumor-related defects in 2 patients and due to giant hairy nevus in 1 patient. The expanders are scalp (19 cases), face (3 cases), supraclaviculer (7 cases) and the neck (1 case) has to be placed. In 4 of 17 patients (three major and one minor) complications were encountered. Use the expander is a good option especially in the reconstruction of soft tissue defects in the head and neck region.