Browsing by Author "Ertekin, A."

Now showing 1 - 4 of 4

Determination of the Status of Lipid Peroxidation and Antioxidants in Cattle Infected With Dictyocaulus Viviparus
(2008) Deǧer, S.; Deǧer, Y.; Ertekin, A.; Gül, A.; Biçek, K.; Ozdal, N.
Endoparasites cause significant economic losses and health problems in domestic animals. In this study, lipid peroxidation and the antioxidant status were investigated in the lung tissue taken from twenty cattle infected with Dictyocaulus viviparus and ten healthy cattle. Malondialdehyde superoxide dismutase, catalase, glutathione, vitamin C and beta-carotene were measured. In comparison to the control group, the concentration of MDA was high (p < 0.001), but the activities of Cu-Zn-SOD and CAT, and the concentration of GSH, vitamin C and beta-carotene were low (Cu-Zn-SOD, CAT, GSH, vitamin C, p < 0.001 and beta-carotene p < 0.05) in the parasite infected group. These results suggested that endoparasitic infection is among the major causes of oxidative stress. Lipid peroxidation was observed and the activities and concentrations of antioxidants systems were decreased in the lungs of cattle infected with Dictyocaulus viviparus.
Effect of Nettle Herb on the Levels of Trace Elements in Rabbits Induced With Dimethylbenzanthracene
(Asian Journal of Chemistry, 2011) Celikezen, F. C.; Ertekin, A.; Turel, I.; Oto, G.
In this study, the effects of nettle herb on the levels of trace elements in rabbits induced with 7,12-dimethylbenzanthracene were studied. Twenty one female New Zealand rabbits were used in the study. The rabbits were divided into three groups. Experiment period was designated as 150 days. The dimethyl sulfoxide (10%) solution with the dosage of 0.5 mL/kg/day was applied in the control group and 7,12-dimethylbenzanthracene dissolved in dimethyl sulfoxide (10 %) solution was applied as 0.5 mL/kg/day in the 7,12-dimethylbenzanthracene group. In addition to 7,12-dimethylbenzanthracene, the extract of nettle herb was applied as 0.2 mL/kg/day to the other group. The blood samples were taken in the end of the experiment. It was determined that there were varying decreases in all tissues of zinc and manganese levels in the 7,12-dimethylbenzanthracene applied group in comparison with the control data, whereas there were increases in all tissues of iron and copper levels. On the other hand, while zinc concentration decreased in all tissues in the nettle herb + 7,12-dimethylbenzanthracene group, manganese, iron and copper concentrations showed an increase in all tissues.
Investigation of the Lipid Peroxidation, Antioxidant Enzymes, Antioxidant Vitamins, Oxidation Products of Nitric Oxide and Some Biochemical Parameters in Chicken With Infectious Bursal Disease (Ibd)
(Eugen Ulmer Gmbh Co, 2016) Ertekin, A.; Yildirim, B. A.; Yildirim, S.; Yildirim, F.; Tutuncu, M.
In the current study, lipid peroxidation, antioxidant enzymes, antioxidant vitamins, oxidation products of nitric oxide and some biochemical parameter levels in chicken with infectious bursal disease were investigated. Thirty chicken were used in the study, 7 in a control group of healthy individuals and the other 23 chickens were infected naturally. The level of advanced oxidation protein products (AOPP) was not affected by the treatment. Vitamin C (P<0.01), nitrite (P<0.01), catalase (P<0.001) and superoxide dismutase (P<0.001) levels were significantly decreased. The levels of malondialdehyde and nitrate increased significantly (P<0.001), while the amounts of ALT (P<0.05) and Albumin (P<0.001) decreased. We also found that changes in glucose, AST, triglyceride and total protein levels were not affected. On the other hand, increases in the levels of LDL (P<0.01), cholesterol and HDL (P<0.05) were significant.
Lipid Peroxidation and Antioxidant Potential of Sheep Liver Infected Naturally With Distomatosis
(2008) Deǧer, Y.; Ertekin, A.; Deǧer, S.; Mert, H.
The aim of this study was to assess the effects of natural distomatosis infections on sheep liver malondialdehyde (MDA) concentration, activities of enzymatic antioxidants (glutathione peroxidase (GPx), superoxide dismutase (Cu, Zn-SOD), catalase (CAT)) and concentrations of non-enzymatic antioxidants (reduced glutathione (GSH), vitamin C, and beta-carotene). Eighteen Akkaraman sheep naturally infected with Fasciola sp and Dicrocoelium dentriticum (D. dentriticum) and ten healthy Akkaraman sheep were included in the study Liver samples for the analysis of MDA, GPx, Cu, Zn-SOD, CAT, GSH, vitamin C, and beta-carotene and blood samples for the measurement of alanine aminotransferase and aspartate aminotransferase were collected immediately after sheep in the two groups were slaughtered. The concentration of MDA and activity of GPx in the group with distomatosis were higher than in the control group (P < 0.001). However, the Cu, Zn-SOD, CAT activities and the GSH, vitamin C concentrations in the infected group were significantly lower than in the control group (P < 0.001). The serum beta-carotene was not found to be statistically different in the two groups (P > 0.05). ALT and AST serum activities of the group with distomatosis were significantly higher in comparison to the control group (P < 0.001). In this study it was demonstrated that lipid peroxidation increased and activities or/and concentrations of antioxidant compounds were significantly changed in the liver of sheep with distomatosis.