Browsing by Author "Gül, A"

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Bcg Vaccination To Prevent Implantation of Endometriosis
(Elsevier Sci Ireland Ltd, 2001) Gül, A; Yasar, T; Ugras, S
To investigate whether BCG vaccination can prevent endometrial implantation in a rat model. Forty sexually mature virgin Wistar-Albino rats weighing 185-215 g were randomly assigned (double-blind) to two groups. The first group (n = 20) were injected with BCG 3 weeks before endometrial implantation to the eye. The second group (n = 20) with BCG not injected before endometrial implantation was the control. Photobiomicroscopy observation was done weekly and 6 weeks post endometrial implantation all eyes were investigated histologically. Five implants grew in the anterior surface of the iris of the first (vaccinated) group and 17 in the second (control) group. The difference was statistically significant. Systemic prophylaxis with BCG can exert an inhibitory effect on endometrial transplantation. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
A Case of Successful Six Consecutive Deliveries in a 41-Year Woman With Uhl's Anomaly
(Elsevier Ireland Ltd, 2003) Güler, N; Demirbag, R; Eryonucu, B; Gül, A
Uhl's anomaly, or parchment right ventricle is a myocardial disorder of unknown cause that mainly involves the right ventricle. Uhl's anomaly may represent a cause of right heart dilatation, failure, and premature sudden death due to ventricular arrhythmias. Although most of the cases of Uhl's anomaly end fatally in infancy or childhood, a limited number of cases have been reported in advanced ages. Also, in pregnant women, this situation increases the risk to both mother and baby and requires special management. This is the first report of six successful consecutive gestations and vaginal deliveries without special managements in a patient with Uhl's anomaly. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
Effects of Methylene Blue, Indigo Carmine Solution and Autologous Erythrocyte Suspension on Formation of Adhesions After Injection Into Rats
(Journals of Reproduction Fertility Ltd, 2000) Gül, A; Kotan, Ç; Dilek, I; Gül, T; Tas, A; Berktas, M
The aim of this study was to determine whether autologous erythrocyte suspension can be used as a dye for evaluation of tubal patency and whether it has any advantages over methylene blue or indigo carmine solutions. Reproductively healthy female nulliparous Wistar Albino rats (n = 30), aged 6 months, mass 165-195 g, were assigned randomly to three groups. Rats received a 1 mi i.p. injection of 5% (w/v) methylene blue solution (methylene blue group: n = 10), 5% (w/v) indigo carmine solution (indigo carmine group: n = 10) or 5% (v/v) fresh autologous erythrocyte suspension (autologous erythrocyte group: n=10). At 4 weeks after injection, a small sterile opening was made in the peritoneal cavity of each rat. The cavity was rinsed once with TCM-199 to collect macrophages. The rinsed peritoneal contents were cultured overnight to evaluate macrophage activation. The peritoneal opening was expanded for evaluation of adhesion formation. Only one rat from the autologous erythrocyte group had intra-peritoneal adhesions (score 2), whereas all rats in the methylene blue group (score 1: n = 1; score 2: n = 4; score 3: n = 4; and score 4: n = 1) and seven rats in the indigo carmine group (score 1: it = 1; score 2: n = 2; score 3: n = 3; and score 4: n = 1) had intra-abdominal adhesions. Macrophage activity was observed in the cultured peritoneal contents collected from the methylene blue and indigo carmine groups but not from the autologous erythrocyte group. Adhesion formation could be due to macrophage activation caused by methylene blue and indigo carmine solutions. These results indicate that tubal patency can be observed by laparoscopy using autologous erythrocyte suspension The results of this study are believed to be the first to indicate that a patient's own erythrocyte suspension could be used during observation of tubal patency by laparoscopy. However, further studies are required.
The Prevalence of Eimeria Species in Goats in Van
(Tubitak Scientific & Technological Research Council Turkey, 2003) Deger, S; Gül, A; Ayaz, E; Biçek, K
This study was carried out to determine Eimeria infection in goats in nine different districts in Van province in Turkey. Faecal samples (approximately 3-5 g) were obtained from the rectums of 242 goats. The samples were examined by Sheather's sugar flotation technique and determined microscopically for the presence of oocysts. Eimeria species were identified following sporulation of faeces in a thin layer of 2.5% potassium dichromate for one or two weeks at 25 degreesC. All samples were later examined for identification of Eimeria species. Nine different species of Eimeria oocysts were detected in 73.6% of the goats. These species were E. arloingi (40.9%), E christensini (34.3%), E. alijevi (32.6%), E. pallida (31.0%), E. hirci (30.2%), E. ninakohliyakimovae (29.8%), E. jolchijevi (26.0%), E. apsheronica (5.8%), and E. punctata (0.8%). Mixed infections were widespread (66.9%). Clinical eimeriosis was not observed.
The Prevalences of Helminth Species According To Faecal Examination in Equids in Different Cities in Turkey
(Scientific Technical Research Council Turkey, 2003) Gül, A; Deger, S; Ayaz, E
The faeces of 464 horses and 110 donkeys were collected and examined by the flotation, sedimentation and Baermenn-Wetzel methods in a parasitology laboratory. The examinations showed that 327 of 464 (70.5%) horses and 85 of 110 (77.3%) donkeys were infected with the following species: in horses, Strongylidae sp. 62.7%. Strongyloides westeri 5.8%, Parascaris equorum 3.2%, Anoplocephalidae sp. 2.4 %, Fasciola hepatica 0.9%, Oxyuris equi 0.6%, and Paranoplocephala mamillana 0.2%; and in donkeys; Strongylidae sp. 72.7%, Strongyloides westeri 13.6%, Parascaris equorum 2.7%, Fasciola hepatica 0.9%, Oxyuris equi 0.9% and Dicrocoelium dendriticum 0.9%.
Repair of Large Incisional Hernias With Multiple Small Relaxing Incisions Technique
(Assoc Soc Scientifique Med Belges, 2000) Kotan, Ç; Gül, A
We report our results in repairing wide incisional hernial defects without using any prosthetic synthetic material, but expanding rectus sheaths by multiple small, 8 to 10 mm, relaxing incisions. In this way, hernial defect becomes smaller and fascial flaps are sutured to each other in an overlapping manner. These relaxing incisions are filled with collagenous connective tissue, and consequently do not cause any abdominal wall weakness. This procedure was performed on 32 patients with hernial defect of 4 x 4 cm to 15 x 15 cm. Mean hospital stay was 6, 8 days. In the follow-up period ranging from 5 to 42 months, no patient presented reccurence of the hernia. Rectus diastasis occurred in one patient who had been operated five times previously. Wound complication such as infection, seroma, haematoma developed in 9 of the patients, and were successfully treated by wound drainage and administration of appropriate antibiotic therapy. The findings of this study led us to conclude that the technique can be used in the repair of incisional hernias as an alternative technique.
Transverse Uterine Incision Non-Closure Versus Closure
(Wiley, 2000) Gül, A; Simsek, Y; Ugras, S; Gül, T
Subject. This study was designed to investigate whether the non-closure of the layers of the uterus during low transverse cesarean section would result in healing and have advantage on closure. Material and method. Thirty pregnant ewes randomly divided into two groups. Each group included 15 ewes. Each ewe was anesthetized at para-vertebral region with the injection of 20 ml Prilocine 2%. Following left transverse abdominal incision, a transverse incision was made on the uterus and lambs were delivered. In the first group, uterine incision line was left open. In the second group, uterine incision line was sutured with no. 1 Chromic catgut by Schimiden technique. In both groups, all layers of abdominal wall except skin were sutured as en-bloc with Vicryl(R) no. 2, by continuous suture technique. Skin was sutured with no. 00 silk interrupted sutures. The ewes were slaughtered four months after cesarean section. A coworker was asked to open the abdominal cavities, and score the intra-abdominal adhesions. Tissues taken from incision line of each uterus were fixed in 10% neutral buffered-formalin and were embedded in paraffin-block. Sections were cut and stained with hematoxylin-eosin. A pathologist, who knew nothing about the study, evaluated all sections, and reported the findings. Strident's t test was used for comparison of mean ewe age, gestational age, and mean operation time of the two groups. Z test was used for comparing the ratio of the two groups by means of histopathological findings. Results. No cervical dilatation and delivery of the placenta were seen during the four week follow up period. The average operating time was significantly less for the non-closure group (48.07+/-3.83 minutes) than for the closure group (62.53+/-6.57 minutes; p=0.001). The ranges of myometrial necrosis (100% versus 13.3%; p=0.001) and endometriosis (53.3% versus 00.0%: p=0.001) were significantly higher for closure group than for non-closure group. Conclusion. It was found that non-closure layers of the uterus along low transverse cesarean incision proves to have no adverse effect on immediate and late postoperative period in ewes. Our data showed that non-closure of all layers of the uterus results in significantly less muscular necrosis and endometriosis than closure group. We suggest that lower uterine incision can be left unclosed or, at least, simple closure can be preferable instead of vigorous locking technique.
Transverse Uterine Incision Non-Closure Versus Closure
(Elsevier Science Bv, 2000) Gül, A; Kotan, Ç; Ugras, S; Alan, M; Gül, T
This study was conducted to test the hypothesis that non-closure of all layers of the uterus during low transverse cesarean section is not associated with increased intra-operative or immediate and late postoperative complication. Eleven pregnant dogs underwent cesarean section for the evaluation of non-closure and closure of all layers of the uterus on immediate or early and late postoperative complication and the effect of suture in tissue. Statistical analysis was performed using Student's t-test for continuous variables and analysis for qualitative variables. Significance was defined as P < 0.05. The ranges of wound infection, other morbidity, and mortality were similar between the groups. The average operating time was significantly less for the non-closure group (71.00 +/- 7.11 min) than for the closure group (92.00 +/- 6.12 min; P < 0.005). Adhesion was significantly less (P < 0.001) for the non-closure group than for the closure group. The ranges of myometrial necrosis (5/5: 100% versus 0/5: 00%; P < 0.001) and fibrosis (2/5. 40% versus 0/5: 00%; P < 0.01) were significantly higher for the closure group than for the open group. It was found that non-closure of all layers of the uterus at low transverse cesarean incision had no adverse effect on immediate and late postoperative complication in dogs. Our data show that non-closure of all layers of the uterus at low transverse cesarean incision results in significantly less muscular necrosis and fibrosis than in the closure group. We suggest that non-closure and/or at least non-vigorous locking bur very simple closure of all layers of the uterus at low transverse cesarean incision may be preferential in appropriate cases. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.