Browsing by Author "Gülhaş, Nurçin"

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    Comparison of the Effects of Dexmedetomidineremifentanil and Propofol-Remifentanil Combinations on Postoperative Cognitive Functions in Patients Undergoing Hysteroscopy: a Randomized Prospective Study
    (2019) Soyalp, Celaleddin; Gülhaş, Nurçin; Atasoy, Idris
    Aim: In the present study, we aimed to compare Dexmedetomidine-Remifentanil and Propofol-Remifentanil combinations in termsof postoperative cognitive functions in hysteroscopy attempts.Material and Methods: A total of 70 ASA I-II patients who were aged between 18 and 65 years were included in the study followingthe ethics committee approval. The patients were randomized into two groups (n=35), and standard routine monitoring were appliedto them. The sedation depth was evaluated with Ramsey Sedation Score (RSS) before and after the sedation; and cognitive functionsof the groups were evaluated with the Minimal Mental State Test (MMST).Propofol 1 mg/kg bolus 25-100 μg/kg/min infusion was administered to Group PR, and Dexmedetomidine 1 μg/kg bolus 0.4-0.7 μg/kg/h infusion dose was administered to Group DR. Remifentanil 0.25 μg/kg bolus 0.04 μg /kg/min infusion was administered to thegroups, and the groups were followed to ensure RSS≥4.Result: In cognitive functions, it was observed that there was significant regression in Group PR in postoperative period comparedto the preoperative period (p<0.05). The hemodynamic parameters were lower in Group DR than in Group PR at 5th, 10th and 15thminutes following the hysteroscopy (p<0.05). The Modified Aldrete Score in Group DR were high, and pain scores were lower (p<0.05).Satisfaction with the surgeon, patient and anesthetist scores were higher in Group DR. No respiratory depression was observed(p<0.05).Conclusion: We believe that administering Dexmedetomidine-Remifentanil combination in sedation in hysteroscopy ensures betterpostoperative cognitive function, recovery conditions, analgesia, and patient and surgeon satisfaction compared to the Propofol-Remifentanil combination.
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    Article
    Effects of Tracheal Intubation Without Muscle Relaxants on Postoperative Recovery Conditions in Patients With Obstructive Sleep Apnea: a Double-Blind Randomized Controlled Study
    (2019) Soyalp, Celaleddin; Gülhaş, Nurçin; Yüzkat, Nureddin; Tuncdemir, Yunus Emre
    Aim: We aimed to compare intubation with and without neuromuscular blocking agents with regard to intubation success,hemodynamic parameters, and postoperative recovery in Obstructive sleep apnea patients.Materials and Methods: The study included 60 patients with a STOP-Bang (Snoring, Tiredness during daytime, Observed apnea,high blood Pressure, Body mass index, Age, Neck circumference, Gender) score of ≥3. The patients were randomly divided into twogroups: (I) rocuronium group (Group E) and (II) remifentanil group (Group R). Group R received 4 mcg/kg remifentanil and Group Ereceived 0.6 mg/kg rocuronium and then the patients’ intubation difficulty scale scores and their responses to train-of-four (TOF)nerve stimulation, and postoperative recovery were evaluated in both groups.Results: The median time to recovery of the TOF ratio to 0 following anesthetic induction was significantly higher in Group Rcompared to Group E (p<0.001). The overall incidences of postoperative sore throat and hoarseness were remarkably high (p<0.002and p<0.001, respectively). The numbers of patients with relaxed vocal cords and complete jaw relaxation were significantly higherin Group E compared to Group R (p<0.001).Conclusion: The results indicated that rocuronium provides better intubation conditions and leads to less peri- and post-operativecomplications compared to remifentanil.