Browsing by Author "Gürbüz, E."

Now showing 1 - 7 of 7

Evaluation of Clinical and Laboratory Findings in Patients Diagnosed With Covid-19
(Verduci International, 2023) Gürbüz, E.; Çelik, M.; Türkoğlu, S.; Elasan, S.; Yürektürk, Ş.; Sünnetçioğlu, M.
Objective: Coronavirus disease 2019 (COVID-19) is an infectious disease that can lead to condi-tions ranging from mild upper respiratory tract infection to severe clinical manifestations, such as respiratory and multiorgan failure. Thus, this study was aimed at evaluating the clinical and laboratory findings of the patients followed up for COVID-19 in our hospital. Patients and Methods: A total of 497 patients who were older than 18 years of age and had been diagnosed with COVID-19 were included in this study. Of the 497 patients diagnosed with COV-ID-19, 57.2% were male and 42.8% were female, and the mean age was 51.59±19.95 years. While the case-death rate was 9.2%, it was 36.8% in the intensive care unit. While lung involvement was detected in 72.2% of the patients, this rate was higher in the patients followed up in the ICU (98.8%). Results: In the laboratory tests, the leukocytosis, lymphopenia, thrombocytopenia, C-reactive pro-tein, alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, creatinine, cre-atine kinase, ferritin, procalcitonin, and D-dimer levels were higher in the deceased patients than in the surviving patients and were associated with mortality. The neutrophil/lymphocyte ratio was higher in the deceased patients when compared to the other patient groups, and it was also associated with increased mortality. Hypertension (8.6%) and diabetes mellitus (11.2%) were the most common underlying diseases in all of the patient groups. Conclusions: It was observed that the case-death rate was significantly higher in the ICU and mortality increased with advanced age. Moreover, comorbid factors were higher in patients who were followed up in the ICU and died. In the laboratory examinations, pathological findings were encoun-tered at a higher rate, especially in the patients who died. © 2023, Verduci International. All rights reserved.
Investigation of Coxiella Burnetii and Ehrlichia Canis by Molecular Methods in Ticks Removed From Patients Admitted To Hospital With Tick Bite Complaints
(ABADER (Adıyaman Bilimsel Arastırmalar Dernegi), 2021) Ekici, A.; Gürbüz, E.; Halidi, A.G.; Ünlü, A.H.; Aydemir, S.
Ticks have to suck blood from their hosts during their developmental stages, except for the egg period. They also transmit the pathogens to their host while feeding. A total of 100 ticks obtained from 42 female and 58 male patients admitted to a hospital were included in the study. After the morphological examination of the ticks, DNA extraction was performed. Conventional PCR for Coxiella burnetii and Nested-PCR for Ehrlichia canis were performed using species-specific primers. In the morphological examination, it was determined that all of the ticks belonged to the Ixodidae family and 95 (95%) were Rhipicephalus sanguineus and 5 (5%) were Ixodes ricinus species. C. burnetii was detected in 36 ticks and E. canis was found in 26 ticks out of 100 ticks included in the study. It was determined that 33 (91.67%) of the C. burnetii infected ticks were R. sanguineus and 3 (8.33%) were I. ricinus. It was also determined that 25 (96.15%) of the E. canis infected ticks were R. sanguineus and one (3.85%) was the I. ricinus. When the incidence of C. burnetii and E. canis was examined according to the place of residence of the patients, it was found that C. burnetii was seen at a higher rate in people living in rural areas and as a result of the statistical analysis, it was found that the difference was statistically significant. In conclusion, ticks pose a significant risk as vectors of C. burnetii and E. canis. © 2021, ABADER (Adıyaman Bilimsel Arastırmalar Dernegi). All rights reserved.
Investigation of Giardia Spp., Cryptosporidium Spp. and Cyclospora Cayetanensis in Samples Collected From Different Spring Waters Iğdır, Türkiye
(Galenos Publishing House, 2023) Akkaş, Ö.; Gürbüz, E.; Aydemir, S.; Şahin, M.; Ekici, A.
Objective: In this study, it was aimed to investigate the physical and chemical properties of different spring waters and parasitic factors with different methods. Methods: This study was carried out on 69 water samples collected from different spring waters in and around Iğdır Province in April and June 2021. The samples were analyzed by native-Lugol, modified acid-fast staining, and nested polymerase chain reaction (nPCR). In addition, altitude (meter) and pressure (mmHg) measurements were made at the point where the water samples were taken. Results: One or more parasites were detected in 27.5% of the 69 water samples examined. Only C. cayetanensis was found in 13% of the samples, only Cryptosporidium spp. in 10.1%, only Giardia spp. in 1.4%, only C. cayetanensis and Giardia spp. in 1.4%, only C. cayetanensis, Cryptosporidium spp., and Giardia spp. in 1.4%. Only Giardia spp. cyst (4.3%) was detected by the direct examination method. While C. cayetanensis and Cryptosporidium spp. oocysts were detected in 8.7% and 7.2% of the samples by the modified acid-fast staining method, C. cayetanensis was detected in 15.9% and Cryptosporidium spp. was detected in 11.6% of the samples by nPCR. When the C. cayetanensis and Cryptosporidium spp. positivity rates were compared according to the characteristics of the water, there was no statistical difference between the altitude, salinity, pH, mmHg, and temperature (kelvin) values, but a significant correlation was found between the amount of dissolved oxygen and Cryptosporidium spp. positivity (p=0.047). Conclusion: Cryptosporidium spp., C. cayetanensis, and G. intestinalis are important waterborne pathogens that can cause epidemics. It is our belief that in order to reduce the risk of contamination of these parasitic factors with spring waters, public awareness should be raised, infrastructures should be improved, and new water treatment techniques, such as ultraviolet, ozonation and monitoring systems, should be used. © 2023 Turkish Society for Parasitology.
Investigation of Intestinal and Blood Parasites in People Returning To Turkey With a History of Traveling Abroad During the Pandemic
(Galenos Publishing House, 2022) Ekici, A.; Gürbüz, E.; Ünlü, A.H.; Yıldız, R.; Aydemir, S.; Halidi, A.G.; Yılmaz, H.
Objective: To investigate intestinal and blood parasites in people who have a history of traveling abroad during the Coronavirus disease-2019 pandemic and returning to Turkey. Methods: In this study, 104 patients with gastrointestinal system and/or fever complaints who had traveled abroad during the pandemic period and returned to Turkey were included. Parasitic agents were investigated by taking blood and stool samples from the patients. Additionally, urine samples were obtained from patients with hematuria or dysuria with the suspicion of schistosomiasis. A direct microscopic examination, the Crypto-Giardia immunochromatographic test, and ELISA methods were used in the examination of the stool samples. In order to detect Plasmodium species, blood samples were examined by preparing both the rapid diagnostic test and thick drop and thin smear preparations. Results: One or more parasite species were detected in 38 (38.5%) of 104 patients included in the study. While intestinal parasites were detected in 16 (32%) of 50 patients who traveled to Iran and 16 (33.3%) of 48 patients who traveled to Northern Iraq, blood parasites were not found. Schistosoma mansoni was detected in all 5 of the patients with a history of traveling to Sudan. Plasmodium falciparum was detected in 1 patient who traveled to the African continent. Conclusion: It is vital to take precautions to prevent parasitic diseases, such as malaria and schistosomiasis, during travels to African countries. During travels to neighboring countries of Turkey, such as Northern Iraq and Iran, hygiene should be paid attention to, so as to prevent contracting intestinal parasitic diseases. In addition, it was concluded that people who plan to travel abroad should have information about the endemic parasitic diseases of the country that they are going to. © 2022 Turkish Society for Parasitology.
Investigation of Pneumocystis Jirovecii in Lung Cancer Patients With the Nested Pcr Method
(Galenos Publishing House, 2022) Halidi, A.G.; Ölçen, M.; Gürbüz, E.; Ekici, A.; Aydemir, S.; Yılmaz, H.
Objective: Pneumocystis jirovecii (P. jirovecii) is an opportunistic pathogen in humans. Early diagnosis and optimal treatment of patients with P. jirovecii pneumonia (PJP) remains a key priority. This study investigated P. jirovecii in patients with lung cancer using the nested-polymerase chain reaction (PCR) method and examined the relationship between P. jirovecii and clinical findings. Methods: The study included 60 patients with lung cancer and 30 patients without lung cancer. The bronchoalveolar lavage (BAL) fluid samples of these 90 individuals were taken for diagnostic purposes in the University of Health Sciences Turkey, Van Training and Research Hospital, Clinic of Chest Diseases. Patient information was recorded. After DNA isolation from the BAL fluid samples taken from patients, the nested-PCR protocol for amplification of mtLSUrRNA in P. jirovecii was performed. Results: P. jirovecii DNA was detected in 40 (66.67%) of the lung cancer patients included in the study and in six (20%) patients without lung cancer, that is, in 46 (51.11%) patients. The rate of nested-PCR positivity in the lung cancer group was significantly higher than that in the non-lung cancer group (p=0.0001). Additionally, a statistically significant correlation was found between anorexia and weight loss, fever and sputum P. jirovecii positivity in patients with lung cancer (p<0.005). Conclusion: These findings suggest that lung cancer patients should be evaluated for PJP. © 2022 Turkish Society for Parasitology.
Investigation of Publication Trends and Hot Topics on Onchocerciasis Between 2000 and 2022
(University of Tabriz, 2023) Alkan, S.; Gürbüz, E.; Aydemir, S.
This study aimed to use bibliometric tools to investigate onchocerciasis research conducted worldwide between 2000 and 2022. This bibliometric study was carried out using the Scopus database. The analysis unit was the documents conducted on onchocerciasis between 2000 and 2022. The data obtained after the last evaluations were transferred to VOSviewer (VOSviewer 1.6.19 for Microsoft Windows systems) and biblioshiny (bibliometrix R package) programs for analysis. The present results showed that 1026 documents on onchocerciasis were indexed in the Scopus database between 2000 and 2022. 2554 authors have published this literature, and the annual growth rate was 1.34 %. Forty-one articles were published in 2000, and after 2014, there was an increase in the number of articles. The most publications were published in 2018 (n = 82). PLOS Neglected Tropical Diseases (n = 97) and Parasites & Vectors (n = 46) published the most publications on onchocerciasis. Most of the publications were published by authors from the United States (n = 341), the United Kingdom (n = 228), Cameroon (n = 150), Nigeria (n = 132), and Germany (n = 120). The documents originating from the United States (n = 2372) had the highest citation numbers. The onchocerciasis research landscape between 2000 and 2022 is outlined in this report. Furthermore, the analysis offers an enhanced comprehension of the trends in onchocerciasis development over the previous 23 years, which might serve as a scientific benchmark for subsequent research. © 2023, Published by University of Tabriz.
A Ruptured Cystic Echinococcosis in the Gallbladder and Intra/Extrahepatic Biliary Tract, Radiological and Surgical Imaging Findings
(Galenos Publishing House, 2023) Türkoğlu, S.; Ekici, A.; Turgut Çoban, L.; Dündar, İ.; Okyay, O.; Gürbüz, E.
Cystic echinococcosis is a common parasitic infestation that can still cause serious complications in endemic areas. Intrabiliary rupture is a well-defined complication, but rupture into the gallbladder is rare. The disease may present with cholecystitis and cholangitis. Clinicians and radiologists working in the emergency room will find the management of the disease much easier if they become familiar with the clinical and radiological findings of the cyst. In this article, a 28-year-old male admitted to the emergency department with acute abdominal pain who was examined for suspected acute cholecystitis and diagnosed with a rupture of the hydatid intra/extrahepatic bile ducts and gallbladder is presented. Our aim is to present the clinical findings and surgical images of the case (ultrasonography, computed tomography, magnetic resonance imaging) and compare them with the literature. © 2023, Galenos Publishing House. All rights reserved.