Browsing by Author "Güven, A.S."

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Alström Syndrome Associated With Cerebral Involvement: an Unusual Presentation
(TIP ARASTIRMALARI DERNEGI, 2006) Yilmaz, C.; Çaksen, H.; Yilmaz, N.; Güven, A.S.; Arslan, D.; Cesur, Y.
Alström syndrome (AS) is a rare autosomal recessive disorder, characterized by retinal degeneration, progressive hearing impairment, truncal obesity and non-insulin dependent diabetes mellitus. A 6-year-old girl was admitted with aphasia, deafness, strabismus, abdominal distention, and weakness on the right body side. The physical and laboratory examination revealed psychomotor retardation, right hemiparesis, sensorioneural hearing loss, aphasia, eye and teeth abnormalities, hyperpigmentation, truncal obesity, hepatosplenomegaly, severe iron deficiency anemia, delayed bone age, and cerebral hemiatrophy. Based on these abnormal findings she was diagnosed as AS. According to our knowledge this is the first case of AS with cerebral involvement. This last finding may be a component of the syndrome.
A Case of Benzydamine Hcl Intoxication
(2006) Doǧan, M.; Yilmaz, C.; Çaksen, H.; Güven, A.S.
Benzydamine HCl is a nonsteroidal anti-inflammatory drug (NSAID) and is available in mouthwash, dermal cream, aerosol and vaginal douche preparations, besides other compounds administered orally or by otic drops. Acute poisoning with benzydamine HCL is associated with agitation, hallucinations, seizures and rarely somnolence. In this study, we reported a rare case of benzydamine poisoning in a girl who presented with somnolence and visual hallucinations one hour after taking five benzydamine HCL dragees orally equal with 14.7 mg/kg for suicide. An 11 years old girl was brought to our hospital because of visual hallucinations. About 1,5 hours before the admission, she received five benzydamine HCL dragees orally for suicide. Visual hallucinations appeared one hour after ingestion of the drug. She especially mentioned to see snakes and her relatives such as her father who was not in the hospital. On laboratory examination complete blood count, serum electrolytes, renal and liver function tests were normal. The patient was hospitalized with the diagnosis of acute benzydamine HCl intoxication. Gastric lavage was performed and activated charcoal (1 g/kg/dose four doses daily) was given. The hallucinations were resolved and she became symptom and sign free two hours after hospitalization. We suggest that if a patient is presented with somnolence and visual hallucinations, drug intoxication should be considered in the differential diagnosis.
Cranial Ct/Mri Findings in Children With Acute Herpes Simplex Encephalitis
(IOS Press, 2007) Çaksen, H.; Ünal, Ö.; Yilmaz, C.; Güven, A.S.; Özen, Ö.
In this study, cranial computerized tomography (CT) and/or magnetic resonance imaging (MRI) findings were investigated in nine children with acute herpes simplex encephalitis (HSE). HSE was confirmed by polymerase chain reaction. Our purpose was to evaluate the diagnostic value of CT and MRI in the diagnosis of HSE and to determine the widespread of the cranial abnormalities in HSE in childhood. Cranial CT was examined in all children and found to be normal in four children. Cranial MRI was examined in seven children, of whom, three was normal. Temporal involvement was diagnosed in only two children. Our findings revealed that the range of cranial involvement was fairly variable in childhood HSE; aside from typical temporal involvement, cranial images may be normal or widespread involvement including basal ganglia, thalamus, frontal and parietal lobes may be seen in children with HSE. © 2007 IOS Press. All rights reserved.