Browsing by Author "Gelincik, Ibrahim"

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Intralesional Bleomycin for Angiolymphoid Hyperplasia
(Amer Medical Assoc, 2007) Akdeniz, Necmettin; Koesem, Mustafa; Calka, Oemer; Bilgili, Serap Gunes; Metin, Ahmet; Gelincik, Ibrahim
Left Ovarian Gonadoblastoma With Yolk Sac Tumor in a Young Woman
(Medknow Publications, 2010) Gelincik, Ibrahim; Ozen, Sueleyman; Bayram, Irfan
Gonodoblastomas with ovarian germ cell tumors other than dysgerminoma coexists very rarely with yolk sac tumor (YST). Because of this rarity, we report a case of gonadoblastoma with YST. An 18-year-old female patient was admitted to our hospital with an abdomino-pelvic mass. Ultrasonographical examinations revealed a 15X14 cm heterogenous pelvic mass with calcific foci in the left adnexal area. Macroscopically, the resected mass was oval and measured 18X15X15 cm and weighed 3150 gm. Histological examination showed both gonadoblastic and YST areas. There were many gonadoblastic nests in the subcapsular areas of the tumor. The gonadoblastic nests were composed of large and small cells. The YST areas showed enteric differentiation and numerous hyaline globules. Immunohistochemical examination may help in the diagnosis of these gonadoblastoma with YST.
Relationship of Pcna, C-Erbb2 and Cd44s Expression With Tumor Grade and Stage in Urothelial Carcinomas of the Bladder
(E-century Publishing Corp, 2014) Yildirim, Ayhan; Kosem, Mustafa; Sayar, Ilyas; Gelincik, Ibrahim; Yavuz, Alparslan; Bozkurt, Aliseydi; Bayram, Irfan
In the present study, the intention was to reveal the relationship of histological grade and stage with c-erbB2, CD44s, and PCNA immunoreactivity in bladder urothelial carcinomas (UC). In our study, we evaluated 46 items of transurethral resection material of patients submitted by YYU Faculty of Medicine, Main Department of Pathology, with a mass revealed in their bladder after clinical and radiological studies at our laboratories and who were diagnosed with urothelial carcinomas. PCNA, c-erbB2, and CD44s were applied in an immunohistochemical manner comprised from nine low-malignant potential papillary urothelial neoplasia, 23 low-grade papillary urothelial carcinoma, and 14 high-grade papillary urothelial carcinoma. Immunostaining was scored according to the percentage of positive cells. The immunohistochemical study demonstrated that the c-erbB2 and PCNA staining ratio increased when an increase occurred in stage and grade. The CD44s staining ratio decreased. C-erbB2, PCNA, and CD44s appear to be a useful marker in the assessment of the prognosis and treatment options in urothelial carcinomas.