Browsing by Author "Gençcelep, M"

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Changes in Certain Biochemical Parameters of Arterial Blood and Cerebrospinal Liquor of Sheep Anaesthetised by Isoflurane and Halothane
(Mezogazda Kiado Kft, 2004) Mercan, N; Atasoy, N; Gençcelep, M; Tas, A
The authors performed biochemical examinations of twenty sheep's arterial blood and cerebrospinal liquor (CSL) to establish the changes caused by inhalation anaesthetics (halothane and isoflurane). Ten animals were anaesthetised by isoflurane (1.5 v/v%) and ten of them by halothane (1 v/v%). Blood samples were taken from a. femoralis and the CSL samples by lumbosacral punction before the anaesthesia (BA), during anaesthesia (DA) and after anaesthesia (AA). From the blood samples pH, pCO(2), pO(2) SAT and HCO3 ion and from the CSL glucose, Na, K and Cl ion-concentration were measured. There were no significant changes (p>0.05) during isoflurane narcosis except CSL glucose content, which was significant (p<0.05). During halothane narcosis pCO(2) and pO(2) DA (p<0.01), HCO3 ion DA (p<0.001), and AA (p<0.05) changed significantly. The results show that sheep tolerate isoflurane better than halothane, because isoflurane did not have unfavourable effects on blood and CSL parameters.
The Effects of Inhalation Anaesthetics (Halothane and Isoflurane) on Certain Clinical and Haematological Parameters of Sheep
(Elsevier Science Bv, 2004) Gençcelep, M; Atasoy, N; Tas, A
In the study, 16 Morkaraman ewes were anaesthetised with 1% halothane (n = 8) and with 1.5% isoflurane (n = 8). Significant differences in respiration rate (P < 0.05) and rectal temperature (P < 0.01) during anaesthesia and total number of WBC (P < 0.05) after anaesthesia for the two treatment groups were recorded. Haematological parameters decreased compared to the values recorded before anaesthesia in both groups. However, the values (WBC, RBC, platelet counts, haemoglobin counts, PCV) were within the physiological limits. All values obtained 24 h following anaesthesia were similar to the values obtained before anaesthesia. Although the chirurgical anaesthesia was conducted with low levels of halothane, the animals recovered earlier from isoflurane than halothane anaesthesia. Isoflurane can be recommended in ewes as it caused a small alteration in the haemotological parameters during anaesthesia and recorded a shorter recovery time. (C) 2003 Elsevier B.V. All rights reserved.
The Effects of Inhalation Anaesthetics Made With Halothane and Isoflurane on Some Biochemical Parameters in Sheep
(Mezogazda Kiado Kft, 2002) Atasoy, N; Gündüz, H; Gençcelep, M; Karakaya, C; Mercan, N
This study was undertaken to determine the effects of halothane and isoflurane on the functions of different organs. A total of 20 sheep were used as material. Ten of them were anaesthetized with halothane (1%) and the other 10 with isoflurane (1.5%). Blood samples were taken from v. jugularis before (BA), during (DA) and after anaesthesia (AA). Sera were collected and analysed for glucose, BUN, creatinine, total bilirubin, AST, ALT, amylase, LDH, CK, CK-MB, ALP, Ca, Na, K and Cl. The effects of the anaesthetics on the parameters were evaluated statistically. These parameters did not change significantly in isoflurane anaesthesia (p>0.05), but in halothane anaesthesia glucose (DA) (p<0.05), creatinine (AA) (p<0.01) and AST (AA) (p<0.05) levels changed significantly. It was concluded that isoflurane can be tolerated better than halothane by sheep and its application did not have destructive effects on the metabolism of pancreas, kidney, liver and muscle.
The Efficacy of Cloxacillin and Micanfin in Multifactorial Conjunctivitis Treatment in Van Cats
(M H Schaper Gmbh Co Kg, 2003) Akkan, HA; Ilhan, Z; Karaca, M; Tütüncü, M; Gençcelep, M; Gülhan, T
This study was performed on 121 Van Cats at the Van Cat Research Center of the Yucuncu YiI University. Out, of 121 cats 20 showed an uni- or bilateral conjunctivitis. The animals were of both sex aging between 1-9 years. The following symptoms were observed in 20 cats with conjunctivitis: serous or seromucous lacrimation, hyperemia and oedema in the conjunctiva and desquamation around their eyes. Hair samples together with hair follicules were taken from comissura medialis and used for bacteriologial and fungal culture. After cultivation, Staphylococcus spp. in 19 cats, Streptococcus spp. in 7 cats and Microsporum spp. in 2 cats were isolated. All the bacteria detected were sensitivite to cloxacillin and to some other antibiotics according to the antibiogram. Cloxacillin (Optidox opht. pom., Sanovel) was applied to both eyes of the all 20 cats. After drug application, 18 cats out of 20 (90%) showed recovery signs starting from 24 hours to 72 hours. However, clinical signs in two cats (10 %) had not disappeared at all. 1.72 hours after drug application, hair samples were taken again for bacteriological analysis. With the exception of these two samples collected from the cats with no clinical improvement, the other 18 samples did not show any bacterial growth. The 2 cats recovered after a second cloxacillin application. The conjunctivitis symptoms disappeared and bacteriological tests made 144 hours after the treatment were negative. After bacteriological elimination, the vaccine Micanfin (Micanfin flk. BioVeta) against Microsporum canis was injected intra-muscularly twice at 14 days intervals. Allergic reactions were not observed on the cats after vaccination. Fungal agents couldn't also be detected 25 and 40 days after vaccination. As a result; cloxacillin was an effective antibiotic in the conjunctivitis caused by Staphylococcus spp., and Streptococcus spp. and Micanfin can safely be used in Van cats without any side effect.