Browsing by Author "Genccelep, Musa"

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Congenital Colo-Vesico Fistula With Atresia Coli, Rectal Agenesis and Atresia Ani Report in Kid
(Ankara Univ Press, 2017) Yildirim, Serkan; Karasu, Abdullah; Genccelep, Musa; Cakmak, Gamze
The material of this case was a four days old male Coloured Angora Goat with congenital anomaly. The purpose of this study was to present findings of congenital colo-vesico-urethral fistula and atresia coli, rectal agenesis and atresia ani clinically, radiographically, macroscopically and histopathologically. According to the clinical examination; anus did not form, animal was dehydrated and not able to get to its feet and had abdominal tension. Besides, few amounts of unclear urine and meconium were present in preputium. By taking into consideration these findings, it was decided to make surgical operation on suspicion of fistula presence between gastrointestinal system and urinary bladder. The animal died during operation. Subsequent to necropsy, colon was swollen and observed at the cranial of pelvis ending bluntly. The blunt end of colon adhered to both urinary bladder and urethra. In order to diagnosis anomaly, samples were obtained from the region where fistulas were present. According to histopathological examination, fistula formation of colon separately to both urethra and urinary bladder was observed. Observing congenital of colo-vesico-urethral fistula, atresia coli, rectal agenesis and atresia ani all in one only in materials rare and may present a good sample for congenital anomaly cases.
The Determination of Radius-Ulna Closure Time of Growth Plates in Mohair Goat Kids by Radiography
(Elsevier Science Bv, 2012) Genccelep, Musa; Karasu, Abdullah; Alpdogan, Osman
In the study, it was aimed to determine the radius-ulna closure time of growth plates in mohair goat kids by radiography and find out the effects of elongation in related bones, shoulders height and gender on closure in accordance to months. The study was carried out in a total 30 kids; 15 being male and 15 female. Until the closure of growth plates of related bones is completed (35 months), radiographies of related bones were taken every month and shoulder heights were measured. Radiographies were taken in ML and LM positions. The lengths of bones seen in the radiogram were measured using negatoscope. Developmental stages of proximal and distal growth plates of radius-ulna were evaluated in four periods according to a modified method. First sign of the start of closure in all the plates among males and females was observed in the proximal plates of radius in the 5th month. In both genders, proximal plates of radius closed in 11-13th month, proximal plate of ulna closed in 25-32nd month, distal plates of radius closed in 33-35th month, distal plate of ulna closed in 34-35th month. As a result, while distal growth plates of radius-ulna closes later compared to proximal plate, it gives an impression that growth in these bones occur mainly in distal plates. One of the reason of the lowerness of shoulder height in the females compared to males, is could be due to early closure time of radius-ulna plates in females compared to males. (C) 2011 Elsevier B.V. All rights reserved.
The Effect of Xylazine Hcl Used in Repeated Sedations for Sheep on Biochemical and Clinical Values
(Kafkas Univ, veteriner Fakultesi dergisi, 2015) Karasu, Abdullah; Genccelep, Musa
The objective of the study is to determine the sedative effects of xylazine HCl administered to sheep in repeated fixed doses clinically and biochemically. Five Akkaraman breed rams identified to be clinically healthy were used in the study. Xylazine HCl was administered 4 times at a dose of 0.4 mg/kg intramuscular (fixed dose) with 4 day intervals to induce sedation. Rectal temperature, heart rate and respiratory rate along with rumen motility of all animals were evaluated before and after the administration. The depths of sedation and analgesia, control of reflexes along with various biochemical parameters were studied. The results showed that xylazine HCl led to change of less physiological parameters in the following administration in comparison with the first application. Whereas only moderate and deep sedation were observed in the first application on sheep; mild, moderate and deep sedation were observed in all remaining administration. The degree of analgesic effect was 0 during mild and moderate sedation periods whereas it was 1-2 during deep sedation period. It was concluded that repeated sedations of xylazine HCl administration reduce the degree of sedation in third and fourth administration in sheep.
Evaluation of Analgesic and Sedative Effects of Repeated and Increasing Doses of Xylazine Hcl in Sheep
(Polish Soc veterinary Sciences Editorial office, 2017) Genccelep, Musa; Karasu, Abdullah
The aim of the study was to investigate the sedative and analgesic biochemical and clinical effects of repeated and increasing doses of xylazine HCl in sheep. Five clinically healthy Akkaraman rams were used. Xylazine was administered intramuscularly at an initial dose of 0.4 mg/kg to induce sedation. The second, third and fourth doses were 20% larger than the previous dose, that is, 0.48, 0.57 and 0.68 mg/kg doses, respectively. They were administered intramuscularly four times at 4-day intervals. The rectal temperature, heart rate and respiratory rate, as well as the rumen motility of all animals, were evaluated before and after xylazine administration. The depths of sedation and analgesia and the control of reflexes, along with various biochemical parameters, were studied. Although the respiration rate increased until the 15th min, it approached the control value at the 30th min and decreased after the 45th min. Ruminal contractions progressively decreased from the 5th min to the 60th min. All levels of sedation were observed in all sheep. The degree of analgesic effect was 0 during mild and moderate sedation periods, and 1-2 during deep sedation. Of all biochemical parameters assessed, only the glucose concentration increased. It was therefore concluded that in order to obtain the same sedation level in sheep in the 4 days following an administration of xylazine, the previous dose should be increased by 20%.
A Field Study on Rational Choice of Medication: the Use of Tilmicosin and Cefquinome in Ovine Footrot Treatment
(Univ Zulia, Facultad Ciencias veterinarias, 2024) Yildiz, Ferit; Genccelep, Musa
In veterinary medicine, it is extremely important to use drugs that will not put human health at risk. In the treatment of animal diseases, the preference of drugs that accumulate in muscle tissue (meat) and are excreted from the body with milk because they create low treatment costs poses a public health and food safety risk. Veterinarians and animal breeders should pay attention to the use of drugs that do not leave residues in animal foods in the treatment of diseases of animals whose meat is eaten. With this study, it was aimed to reveal the healing time of Tilmicosin, which passed to milk and Cefquinome, which is not passed to milk are used in the treatment of footrot, especially in sheep raised for meat and milk, and what are the costs (medicine, labor, etc.) of both drugs to animal owners. The study was conducted on 80 sheep with footrot from sheep raised in Mud, T & uuml;rkiye in 2020-21. As a result of field observations, anamnesis and clinical examinations, sheep with footrot were divided into two groups in equal numbers. One group was administered Cefquinome (1 mL50 kg-1 im. every 24 hours -h-, 3 applications), while the other group was administered Tilmicosin (1 mL30 kg-1sc.-1 sc. 48 h later, 2 applications) and the animals were observed for 10 day (d). In the Cefquinome group, footrot could be treated at a rate of 90% on the 4 th d and did not bring additional costs to the animal owners. It has been concluded that Cefquinome should be preferred in treatment in terms of animal health, food safety and public health due to its high treatment success, easy application in pasture conditions, and the availability of milk during treatment.
Prevention of Wrap Disruption After Antireflux Surgery: an Experimental Study
(Nobel Ilac, 2015) Ilce, Zekeriya; Ozaydin, Ismet; Iskender, Abdulkadir; Aydin, Metin; Kisli, Erol; Genccelep, Musa
Objective: The worst complication after a fundoplication is the disruption of the fundic wrap which is the main cause of recurrent gastro-esophageal reflux. The purpose of this experimental study is to seek for an alternative technique to prevent wrap-breakdown. Material and Method: The experiments were carried out on thirty canine subjects those were randomly allocated into 3 groups for performance of a Nissen procedure. Silk sutures were used for construction of the fundic wrap in Group I, silk sutures and fibrin glue were used in Group II and only fibrin glue was used in Group III for the same purpose. Operation durations were noted as minutes. The break-down force of the fundic wrap was measured and recorded. The results were recorded as kg and statistical examinations were performed by SPSS 13.0 statistical software program. The intergroup comparisons were performed with Kruskal-Wallis and Mann-Whitney U tests. p was significant at <0.05 Results: No post-operative complications were observed and all the animals survived until the post-operative 2nd month when they were euthanized and the wrap break-down forces were determined. The break-down force was 11.2 kg in Group I, 17.3 kg in Group II, and 11.5 kg in Group III. The difference between group I and II, with group III was statistically significant (p<0.05). But group I and III was not statistically significant (p>0.05). Operation times were 47.9 in Group I, 53.2 in Group II and 28.38 minutes in Group III. Operation times were significantly longer in Group II than in Group I and III (p<0.05), and significantly shorter in Group III than in Groups I and II (p<0.05). Conclusion: We believe that, application of the fibrin glue together with the conventional suturing technique in construction of the fundoplication may prevent wrap-breakdown after the Nissen antireflux procedure.
Serum Retinol, Alpha-Tocopherol, Cholecalciferol, and Some Mineral Levels in Ruminants With Congenital Digestive and Urogenital System Anomalies1
(Revista Pesquisa veterinaria Brasileira, 2024) Karasu, Abdullah; Genccelep, Musa; Kayikci, Caner; Kuscu, Yagmur
This study aimed to investigate the relationship between serum vitamin and mineral levels and congenital defects in digestive and urogenital system anomalies in calves, lambs, and kids. The study material consisted of 13 calves, 15 lambs, 10 kids clinically and radiologically diagnosed with congenital digestive and urogenital system anomalies and 10 newborn clinically healthy calves, 10 lambs, and 10 kids. Congenital defects were diagnosed by clinical and radiological examination. Blood samples were collected from all animals, and sera were extracted for biochemical analysis. Vitamins A, D, and E, calcium, phosphorus, sodium, potassium, chlorine, magnesium, copper, iron, zinc, selenium, and manganese levels were measured in serum samples. Penile urethral diverticulum in kids, atresia ani, atresia ani with vaginal fistula in lambs, and atresia ani and atresia coli defects in calves were determined. Copper levels were higher, and zinc levels were lower in kids with penile urethral diverticulum compared to the control group. Vitamin A levels were lower in lambs with digestive system anomalies compared to the control group. Meanwhile, copper levels were higher in lambs with digestive system anomalies. Vitamin A and D levels were lower in calves with digestive system anomalies compared to the control group. There was no difference in the levels of the other parameters compared to the control group. In conclusion, insufficient serum vitamin A levels may play a role in the etiopathogenesis of congenital intestinal atresia in calves and lambs. Therefore, we believe that parenteral vitamin A administration to the mother, especially in the last trimester of pregnancy in regions with continental climates and poor green vegetation, would be beneficial. Further research should be conducted to determine the role of vitamin A in the etiopathogenesis of congenital atresia ani and coli.